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1887篇 您的检索式:作者名="Picard"
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13D bioactive composite scaffolds for bone tissue engineering显示文摘Bone is the second most commonly transplanted tissue worldwide,with over four million operations using bone grafts or bone substitute materials annually to treat bone defects.However,significant limitations affect current treatment options and clinical demand for bone grafts continues to rise due to conditions such as trauma,cancer,infection and arthritis.Developing bioactive three-dimensional(3D)scaffolds to support bone regeneration has therefore become a key area of focus within bone tissue engineering(BTE).A variety of materials and manufacturing methods including 3D printing have been used to create novel alternatives to traditional bone grafts.However,individual groups of materials including polymers,ceramics and hydrogels have been unable to fully replicate the properties of bone when used alone.Favourable material properties can be combined and bioactivity improved when groups of materials are used together in composite 3D scaffolds.This review will therefore consider the ideal properties of bioactive composite 3D scaffolds and examine recent use of polymers,hydrogels,metals,ceramics and bio-glasses in BTE.Scaffold fabrication methodology,mechanical performance,biocompatibility,bioactivity,and potential clinical translations will be discussed.Gareth Turnbull Jon Clarke Frederic Picard Philip Riches Luanluan Jia Fengxuan Han Bin Li Wenmiao Shu 2018Bioactive Materials2018,3,3:40
2从法国公共电力企业的视角看大数据带来的挑战和机遇显示文摘大数据、数据分析、数据科学,以及与数据相关的创新技术正广泛应用在各领域企业的技术研发和商业模式中。其中,基于大数据的应用和决策制定是能源企业的核心发展方向,大数据和数据分析也是智能电网的核心内容之一。广泛地说,数据及其相关应用是技术创新和附加价值的载体,对企业的战略发展以及创新产品和服务的开发至关重要。因此,大量数据的产生和新一代信息系统的开发为国际能源大舞台的参与者们提供了新的可能性和商机。文章首先概述大数据的相关背景,然后介绍法国电力集团研究院在大数据领域的相关研究工作,最后对下一步的研究工作进行了展望。Marie-Luce PICARD 潘旭阳 2015电网技术2015,39,11:13
3针刺治疗偏头痛60例急性期临床疗效评价显示文摘目的:观察针刺治疗偏头痛的临床疗效。方法:针刺主穴率谷、头维、太阳、风池,并辨证选穴治疗偏头痛60例,所有的观察对象均在治疗前、治疗后0.5、2、4、24、72h分别进行4分量表(4-point scale)和视觉模拟量表(visual ana-logue scale,VAS)的测评,以观察治疗前后各时间段患者偏头痛程度的变化。结果:治疗后各时间段比治疗前4 pointscale与VAS评分差异有统计学意义(P<0.01),评分明显改善。结论:针刺治疗偏头痛72h内症状明显缓解,近期疗效显著。王舒 陈祥芳 郭琳 樊小农 丁晓蓉 David Picard 石学敏(指导) 2006辽宁中医杂志2006,33,11:10
4针刺预防治疗偏头痛59例临床疗效观察显示文摘[目的]观察针刺治疗偏头痛的预防治疗疗效。[方法]演针刺主穴率谷、头维、太阳、风池,并辨证选穴治疗偏头痛60例,所有的观察对象均在治疗前、治疗后3个月和治疗后6个月时分别进行偏头痛失能评价(MIDAS)测评,以观察治疗前后各时间段患者偏头痛疼痛程度的变化。[结果]治疗后3个月与治疗后6个月比治疗前MIDAS评价均有改善,差异有极显著性意义(P<0.01);治疗后6个月与治疗后3个月比较,差异无显著性意义(P>0.05)。[结论]治疗后3个月与6个月症状改善明显,6个月与3个月相比没有明显差别。针刺对偏头痛具有较好的预防治疗作用。陈祥芳 樊小农 刘健 郭琳 郭丽 石学敏 David Picard 2007天津中医药2007,24,1:7
5针刺治疗60例急性期偏头痛疗效观察显示文摘郭丽 樊小农 陈祥芳 郭琳 刘健 David Picard 石学敏 2006上海针灸杂志2006,25,11:7
6Prospective evaluation of the Sedation-Agitation Scale for adult critically ill patients显示文摘Richard R. Riker Jean T. Picard Gilles L. Fraser 1999Critical Care Medicine1999,,7:5
7Sensory quality of meat from eight different types of cattle in relation with their biochemical characteristics显示文摘The present study compared eight breeds of cattle differing in gender(heifers, bulls and steers) to determine associations between muscle characteristics and meat sensory qualities of the Longissimus thoracis muscle. Animal types differed in all the muscle characteristics and sensory qualities. Many correlations among muscle characteristics and among sensory qualities were consistent for most animal types. Isocitrate dehydrogenase(ICDH) activities allowed discrimination of muscles with respect to myosin heavy chain(My HC)-I proportions for all animal types. Lactate dehydrogenase(LDH) and phosphofructokinase(PFK) activities were positively correlated for most animal types. Overall liking was correlated with beef flavour and abnormal flavour in all animal types and with global tenderness for all animal types except for Charolais cross breed steers. For all animal types except for Angus×Friesian heifers, beef flavour and abnormal flavour were negatively correlated. Overall liking was not correlated with juiciness. PFK, ICDH and citrate synthase(CS) activities were strongly associated with tenderness, beef flavour and overall liking when average values for all animal types were used. However, associations between muscle characteristics and sensory qualities within animal types were weak and inconsistent.M Gagaoua E M C Terlouw D Micol J-F Hocquette A P Moloney K Nuernberg D Bauchart A Boudjellal N D Scollan R I Richardson B Picard 2016Journal of Integrative Agriculture2016,15,7:3
8Frequent amplification of a chr19q13.41 microRNA polycistron in aggressive primitive neuroectodermal brain tumors显示文摘Li M Lee KF Lu Y Clarke I Shih D Eberhart C Collins VP Van Meter T Picard D Zhou L Boutros PC Modena P Liang ML Scherer SW Bouffet E Rutka JT Pomeroy SL Lau CC Taylor MD Gajjar A Dirks PB Hawkins CE Huang A. 2009中国神经肿瘤杂志2009,7,4:3
9NeuroAid (MLC601) versus piracetam in the recovery of post-infarct homonymous hemianopsia显示文摘In the clinic,the natural recovery rate of homonymous hemianopsia caused by occipital lobe infarction is low.At present,ideal therapeutic effects of piracetam for improving visual field defects following homonymous hemianopsia do not exist.The present randomized,controlled study compared the effects of NeuroAid (MLC601) versus piracetam for improving visual field defects in post-infarct homonymous hemianopsia patients matched for age and sex.After 3 months of treatment with NeuroAid (MLC601) or piracetam,visual field defects were significantly improved,compared with prior to treatment (P < 0.001).After treatment with MLC601,relative reduction of right and left visual field defects was 45% and 45.7%,respectively,while relative reduction after treatment with piracetam was 32.7% and 30.3%,respectively.These findings suggested that MLC601 was superior to piracetam for reducing visual field defects in homonymous hemianopsia patients.Kavian Ghandehari Zahra Izadi Mood Saeed Ebrahimzadeh David Picard Yue Zhang 2011Neural Regeneration Research2011,6,6:3
10风土营销:葡萄酒旅游经济显示文摘探讨在葡萄酒业中旅游如何作为战略营销工具用于品牌推广,并从多角度论证葡萄酒旅游成功的运营模式。基于在全球主要葡萄酒产地的比较研究可知,通过为游客提供戏剧性、仪式性的休闲旅游环境,葡萄酒生产商及分销商可以成功塑造并提升葡萄酒产品品牌形象。David Picard Catarina Moreira 撒露莎 2017中南民族大学学报(人文社会科学版)2017,37,1:2
11卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景 缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 2017国际脑血管病杂志2017,25,5:2
12水滑石复配氢氧化铝对氯丁橡胶阻燃性能和力学性能的影响显示文摘采用机械共混法制备了水滑石(LDH)/氢氧化铝(ATH)/白炭黑填充的氯丁橡胶(CR)复合材料,考察了LDH用量对CR基复合材料硫化特性、填料分散性、热稳定性、力学性能和阻燃性能的影响。结果表明:与未加LDH的试样相比,添加LDH后CR混炼胶的交联程度和硫化速率下降。当LDH质量份为5份时,体系具有较好的填料分散性。随着LDH用量的增加,CR/ATH/LDH/白炭黑硫化胶的拉伸强度略微下降,定伸应力先下降后升高,热氧稳定性和氧指数不断提高,特别是当LDH质量份超过10份以后,CR硫化胶的热释放速率峰值以及总释放热均维持在较低水平。赵盛钦 李建兴 毛园珍 赵树高 Loïc PICARD Laina GUO 王鹤 2021青岛科技大学学报(自然科学版)2021,42,6:2
13Fine Particle Monolayers Made by a Mobile Dynamic Thin Laminar Flow (DTLF) Ddevice 显示文摘PICARD G 1998Langmuir1998,14,13:1
14Cytological effects of cellulases in the parasitism of Phytophthora parasitica by Pythium oligandrum显示文摘Picard K Tirilly Y Benhamou N 2000Applied and Environmental Microbiology2000,66,10:1
15Evaluation de la disponibilite des acides amines; choix raisonne dune methode显示文摘Laplace J P Darcy-vrillon B Picard M 1985J Rech Porcine Fr1985,17,:1
16Sirt1 regulates insulin secretion by repressing UCP 2 in pancreatic beta cells显示文摘Bordone L Motta MC Picard F 2006PLoS Biol2006,4,2:1
17Correlation between ribosomal DNA polymorphism and electrophoretic enzyme polymorphism in Yerslnia显示文摘Picard-Pasquier N Picard B Heeralal S 1990J Gen Microbiol1990,136,:1
18Agircuhural sector and industrial agglomeration 显示文摘Pierre M Picard Zeng Dao-Zhi 2005Journal of Development Economics2005,,77:1
19Supplemental studies for cardiovascular risk assessment in safety pharmacology:a critical overview显示文摘Picard S Goineau S Guillaume P Henry J Hanouz JL Rouet R 2011Cardiovasc Toxicol2011,11,4:1
20Opportunities for predicting and manipulating beef quality显示文摘HOCQUETTE J F BOTREAU R PICARD B 2011Meat Science2011,92,:1
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