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6篇 您的检索式:作者名="Sebastian Stintzing"
    题名 作者 年代 出处 被引量
1Hepatocellular carcinoma: Therapeutic advances in signaling,epigenetic and immune targets显示文摘Hepatocellular carcinoma(HCC)remains a global medical burden with rising incidence due to chronic viral hepatitis and non-alcoholic fatty liver diseases.Treatment of advanced disease stages is still unsatisfying.Besides first and second generation tyrosine kinase inhibitors,immune checkpoint inhibitors have become central for the treatment of HCC.New modalities like epigenetic therapy using histone deacetylase inhibitors(HDACi)and cell therapy approaches with chimeric antigen receptor T cells(CAR-T cells)are currently under investigation in clinical trials.Development of such novel drugs is closely linked to the availability and improvement of novel preclinical and animal models and the identification of predictive biomarkers.The current status of treatment options for advanced HCC,emerging novel therapeutic approaches and different preclinical models for HCC drug discovery and development are reviewed here.Daniel Neureiter Sebastian Stintzing Tobias Kiesslich Matthias Ocker 2019World Journal of Gastroenterology2019,25,25:4
2Clinical relevance of EGFR- and KRAS-status in colorectal cancer patients treated with monoclonal antibodies directed against the EGFR显示文摘Volker Heinemann Sebastian Stintzing Thomas Kirchner Stefan Boeck Andreas Jung 2008Cancer Treatment Reviews2008,,3:3
3Early tumor shrinkage in patients with metastatic colorectal cancer receiving first-line treatment with cetuximab combined with either CAPIRI or CAPOX: An analysis of the German AIO KRK 0104 trial显示文摘Dominik P. Modest Ruediger P. Laubender Sebastian Stintzing Clemens Giessen Christoph Schulz Michael Haas Ulrich Mansmann Volker Heinemann 2013Acta Oncologica2013,,5:2
4Clinical relevance of EGFR- and KRAS-status in colorectal cancer patients treated with monoclonal antibodies directed against the EGFR显示文摘Volker Heinemann Sebastian Stintzing Thomas Kirchner Stefan Boeck Andreas Jung 2008Cancer Treatment Reviews2008,,3:1
5Different capabilities of morphological pattern formation and its association with the expression of differentiation markers in a xenograft model of human pancreatic cancer cell lines显示文摘Daniel Neureiter Steffen Zopf Arno Dimmler Sebastian Stintzing Eckhart G. Hahn Thomas Kirchner Christoph Herold Matthias Ocker 2005Pancreatology . 2005 (4-5)2005,,:1
6Early tumor shrinkage in metastatic colorectal cancer: Retrospective analysis from an irinotecan‐based randomized first‐line trial显示文摘Clemens Giessen Ruediger P. Laubender Ludwig Fischer von Weikersthal Andreas Schalhorn Dominik P. Modest Sebastian Stintzing Michael Haas Ulrich R. Mansmann Volker Heinemann 2013Cancer Sci2013,,6:1
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