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| 1 | Current status of intravenous tissue plasminogen activator dosage for acute ischaemic stroke:an updated systematic review显示文摘The optimal dose of recombinant tissue plasminogen activator(rtPA)for acute ischaemic stroke(AIS)remains controversial,especially in Asian countries.We aimed to update the evidence regarding the use of low-dose versus standard-dose rtPA.We performed a systematic literature search across MEDLINE,Embase,Cochrane Central Register of Controlled Trials(CENTRAL),PsycINFO and Cumulative Index to Nursing and Allied Health Literature(CINAHL)from inception to 22 August 2016 to identify all related studies.The outcomes were death or disability(defined by modified Rankin Scale 2-6),death,and symptomatic intracerebral haemorrhage(sICH).Where possible,data were pooled for meta-analysis with ORs and corresponding 95% CIs by means of random-effects or fixed-effects meta-analysis.We included 26 observational studies and 1 randomised controlled trial with a total of 23210 patients.Variable doses of rtPA were used for thrombolysis of AIS in Asia.Meta-analysis shows that low-dose rtPA was not associated with increased risk of death or disability(OR 1.13,95% CI 0.95 to 1.33),or death(OR 0.86,95% CI 0.74 to 1.01),or decreased risk of sICH(OR 1.06,95% CI 0.65 to 1.72).The results remained consistent when sensitivity analyses were performed including only low-dose and standard-dose rtPA or only Asian studies.Our review shows small difference between the outcomes or the risk profile in the studies using low-dose and/or standard-dose rtPA for AIS.Low-dose rtPA was not associated with lower risk of death or disability,death alone,or sICH. | Xia Wang Shoujiang You Shoichiro Sato Jie Yang Cheryl Carcel Danni Zheng Sohei Yoshimura Craig S Anderson Else Charlotte Sandset Thompson Robinson John Chalmers Vijay K Sharma | 2018 | Stroke & Vascular Neurology2018,3,1: | 10 |
| 2 | Aclivation of the precursor of gelatinase A/72 KD type Ⅳ colleguenase/MMP-2 in lung carcinomas correlates with the expression of membrane-type matrix metalloproteinase and with lymph node metastasis显示文摘 | Tokurku M Sato H Murakami S | 1995 | Int J Cancer1995,,: | 5 |
| 3 | An automated spring-loaded needle for endoscopic ultrasound-guided abdominal paracentesis in cancer patients显示文摘AIM: To evaluate the feasibility of using an automatedspring-loaded needle device for endoscopic ultrasound(EUS)-guided abdominal paracentesis(EUS-P) to see if this would make it easier to puncture the mobile and lax gastric wall for EUS-P.METHODS: The EUS database and electronic medical records at Fukushima Medical University Hospital were searched from January 2001 to April 2011. Patients with a history of cancer and who underwent EUS-P using an automated spring-loaded needle device with a 22-gauge puncture needle were included. The needle was passed through the instrument channel and advanced through the gastrointestinal wall under EUS guidance into the echo-free space in the abdominal cavity and ascitic fluid was collected. The confirmed diagnosis of malignant ascites included positive cytology and results from careful clinical observation for at least 6 mo in patients with negative cytology. The technical success rate, cytology results and complications were evaluated.RESULTS: We found 11 patients who underwent EUS-P with an automated spring-loaded needle device. In 4 cases, ascites was revealed only with EUS but not in other imaging modalities. EUS-P was done in 7 other cases because there was minimal ascitic fluid and no safe window for percutaneous abdominal aspiration. Ascitic fluid was obtained in all cases by EUS-P. The average amount aspirated was 14.1 mL(range 0.5-38 mL) and that was sent for cytological exam. The etiology of ascitic fluid was benign in 5 patients and malignant in 6. In all cases, ascitic fluid was obtained with the first needle pass. No procedure-related adverse effects occurred.CONCLUSION: EUS-P with an automated springloaded needle device is a feasible and safe method for ascites evaluation. | Rei Suzuki Atsushi Irisawa Manoop S Bhutani Takuto Hikichi Tadayuki Takagi Goro Shibukawa Ai Sato Masaki Sato Tsunehiko Ikeda Ko Watanabe Jun Nakamura Srinadh Annangi Kazuhiro Tasaki Katsutoshi Obara Hiromasa Ohira | 2014 | World Journal of Gastrointestinal Endoscopy2014,6,2: | 3 |
| 4 | Delayed neuronal death in the CA1 pyramidal cell layer of the gerbil hippocampus following transient ischemia is apoptosis显示文摘 | Nitatori T Sato N Waguri S | 1995 | J Neurosci1995,15,: | 2 |
| 5 | Transfection of p27 (Kip1) threonine residue 187 mutant type gene, which is not influenced by ubiquitin-mediated degradation,induces cell cycle arrest in oral squamous cell carcinoma cells显示文摘 | Kudo Y Kitajima S Sato S | 2002 | Oncology2002,63,4: | 2 |
| 6 | Targeted Disruption of Cbfa1 Results in a Complete Lack of Bone Formation owing to Maturational Arrest of Osteoblasts显示文摘 | T Komori H Yagi S Nomura A Yamaguchi K Sasaki K Deguchi Y Shimizu R.T Bronson Y.-H Gao M Inada M Sato R Okamoto Y Kitamura S Yoshiki T Kishimoto | 1997 | Cell1997,,5: | 2 |
| 7 | 尿酸是正常高值血压发展为高血压的一个重要危险标志物显示文摘正常高值血压常发展为高血压,是一个与心血管病和脑卒中高死亡率和高发病率相关的事件。然而,正常高值血压发展成高血压的危险因素仍不清楚。研究者采用年龄(52.1±11.0)岁日本成年高血压患者3584例(2081例为男性)的资料进行前瞻性群体研究,研究对象在2004年被发现处于正常高值血压阶段,并在2009年重新进行检查。 | 黄洁 叶鹏 Kuwabara M Hisatome I Niwa K Hara S Roncal-Jimenez CA Bjornstad P Nakagawa T Andres-Hernando A Sato Y Jensen T Garcia G Rodriguez-Iturbe B Ohno M Lanaspa MA Johnson RJ | 2017 | 中华高血压杂志2017,25,12: | 2 |
| 8 | Protective effect of taurine against renal interstitial fibrosis of rats induced by cisplatin显示文摘 | Sato S Yamate J Saito T | 2002 | Naunyn Schmiedebergs Arch Pharmacol2002,365,: | 2 |
| 9 | Radiation Lobectomy: time-dependent analysis of future liver remnant volume in unresectable liver cancer as a bridge to resection显示文摘 | Michael Vouche Robert J. Lewandowski Rohi Atassi Khairuddin Memon Vanessa L. Gates Robert K. Ryu Ron C. Gaba Mary F. Mulcahy Talia Baker Kent Sato Ryan Hickey Daniel Ganger Ahsun Riaz Jonathan Fryer Juan Carlos Caicedo Michael Abecassis Laura Kulik Riad S | 2013 | Journal of Hepatology2013,,: | 2 |
| 10 | 显示文摘 | Sato S | 1986 | Chemical Physics Letters1986,123,12: | 2 |
| 11 | Expression ofperoxisome proliferator-activated receptor (PPAR)gamma in gastric cancer and inhibitory effects of PPAR gamma agonists显示文摘 | Sato H Ishihara S Kawashima K | 2000 | Br J Cancer2000,83,: | 2 |
| 12 | Ketonization of carboxylic acids over CeO2-based composite oxides显示文摘 | Nagashima O Sato S Takahashi R | 2005 | Journal of Molecular Catalysis A: Chemical2005,227,12: | 1 |
| 13 | Visible-light sensitization of TiO2 photocatalysts by wet-method n doping显示文摘 | Sato S Nakamura R Abe S | 2005 | Appl Catal A2005,284,: | 1 |
| 14 | Feasibility of magnetic liposomes as a targeting device for drug 显示文摘 | Kiwada H Sato J Yamada S | 1986 | Chem Pharm Bull1986,34,: | 1 |
| 15 | Tako-tsubo-like left ventricular dysfunction with ST-segment elevation:a novel cardiac syndrome mimicking acute myocardial Infarction显示文摘 | Kurisu S Sato H Kawagoe T | 2002 | Am Heart J2002,143,: | 1 |
| 16 | Rhodium(I)-or ruthenium(II)-catalyzed direct coupling of vinyl ketones with aldehydes and the subsequent reduction to give aldol derivatives anti-selectively显示文摘 | Sato S Matsuda L Shibata M | 1989 | J Organomet Chem1989,377,: | 1 |
| 17 | Properties of two VEGF receptors, Flt-1 and KDR, in signal transduction 显示文摘 | Sato Y Kanno S Oda N | 2000 | Ann NY Acad Sci2000,902,: | 1 |
| 18 | Preparation and properties of salt-induced gel of whey protein显示文摘 | NAKAMURA M SATO K KOIZUMI S | 1995 | Journal of Japanese Society of Food Science and Technology1995,42,1: | 1 |
| 19 | Growth factor-induced phosphorylation of sterol regulatory element-bind ing proteins inhibits sumoylation, thereby stimulating the ex pression of their target genes,low density lipoprotein uptake, and lipid synthesis显示文摘 | Arito M Horiba T Hachimura S Inoue J Sato R | 2008 | J Biol Chem2008,283,15: | 1 |
| 20 | Fabrication of high -- quality opal films with controllable thickness 显示文摘 | Gu Z Z Fujishima A Sato S | 2002 | Chem Mater2002,14,2: | 1 |