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| 1 | Intratumoral dendritic cell vaccin ation elicits potent tumoricidal im munity against malignant glioma in rats显示文摘Dendritic cells(DC)are attractive candidates for innovative cancer immunotherapy by virtu e of their ability to function as powe rful antigen presenting cells and elicit potent antitumor cytotoxic immune r esponses.With the aim of generating antitumor immunity,the authors sought to enhance in vivo tum or antigen presentation by using an i ntratumoral DC vaccination strateg y in the setting of partially irradiated intracranial brain tumo rs.Fisher rats,implanted with 9L gliomas in the right corpus striatum,w ere treated with freshly cultured,unpulsed syngeneic DC inoculated directly into the tumor bed.Intracranially inoculated DCs were found to drain to ipsilateral deep cervical lymph nodes.This was a ssociated with increased local and s ystemic antitumor cytoxicity,as evidenced by robust infiltration of treated tumors with CD4and CD8T ce lls as well as by increased IFN-gamma protein and message levels in in vitr o restimulated splenic lymphocytes.DC therapy resulted in prolonged survival and immunity to s ubsequent intracranial tumor re-ch allenge.These results demonstrate the viability of intratumoral DC vaccination as an effectiv e therapeutic strategy for intracra nial glioma. | Ehtesham M Kabos P Gutierrez MA Samoto K Black KL Yu JS | 2003 | 癌症2003，22，7： | 8 |
| 2 | Treatment of intracranial glioma with in situ interferon-gamma and tumor necrosis factor-alpha gene transfer 显示文摘 | Ehtesham M Samoto K Kabos P | 2002 | Cancer Gene Ther2002，9，11： | 1 |
| 3 | Comparative results of conservative treatments for isolated anterior talofibular ligament (ATFL) injury and injury to both the ATFL and calcaneofibular ligament of the ankle as assessed by subtalar arthrography显示文摘 | Norihiro Samoto Kazuya Sugimoto Takanori Takaoka Tadashi Fujita Chikara Kitada Yoshinori Takakura | 2007 | Journal of Orthopaedic Science2007，，1： | 1 |
| 4 | Colon cacer screening by a new test:a prospective study of asymptomatic population显示文摘 | Samoto K Muratani M Ogawa J | 1993 | Proc AM ASSOC Cancer Res1993，32，： | 1 |
| 5 | Increased expression of Bcl-2 protein in human uterine leiomyoma and its up-regulation by progesterone显示文摘 | Matsuo H Maruo T Samoto T | 1997 | J Clin Endocrinol Metab1997，82，1： | 1 |
| 6 | Expression of vascular endothelial growth factor and its possible relation with neovascularization in human brain tumors 显示文摘 | Ikezaki K Ono M | 1995 | Cancer Res1995，55，： | 1 |
| 7 | Diagnosis of discoid lateral meniscus of the knee on MR imaging 显示文摘 | Samoto N Kozuma M Tokuhisa T | 2002 | Magn Reson Imaging2002，20，1： | 1 |
| 8 | Treatment of mouse limb ischemia with an integrative hypoxia-responsive vector expressing the vascular endothelial growth factor gene 显示文摘 | Yasumura E G Stilhano R S Samoto V Y | 2012 | PLoS One2012，7，33： | 1 |
| 9 | Improvement of the off-flavor of soy protein isolate by removing oil-body associated proteins and polar lipids显示文摘 | SAMOTO M MIYAZAKI C KANAMOR J | 1998 | Bioscience Biotechnology Biochemistry1998，62，5： | 1 |
| 10 | Abundant proteins associated with lecithin in soy protein isolate显示文摘 | Samoto M Maebuchi M Miyazaki C | 2007 | Food Chemistry2007，102，1： | 1 |
| 11 | Expression of vascμlar endothelial growth factor and its possible relation with neovascμlarization in human brain tumors显示文摘 | Samoto K Ikozaki K Ono M | 1995 | Cancer Res1995，55，： | 1 |
| 12 | Substantially complete removal of three major allergenic soybean proteins (Gly m Bd 30K,Gly m Bd 28K,and the alpha subunit of conglycinin) from soy protein by using a mutant soybean,Tohoku 124显示文摘 | Samoto M Fukuda Y Takahashi K | 1997 | Biosci Biotech Biochem1997，61，： | 1 |
| 13 | Abundant proteins associated with lecithin in soy protein isolate显示文摘 | SAMOTO M MAEBUCHI M CHIAKI M | 2007 | Agric Food Chem2007，102，1： | 1 |
| 14 | Substantially complete removal of the 34 kDa allergenic soybean protein,Gly m Bd 30K,from soy milk of a mutant lacking with alpha-and alpha′-subunits of conglycinin显示文摘 | Samoto M Takahashi K Fukuda Y | 1996 | Biosci Biotech Biochem1996，60，： | 1 |
| 15 | A rapid PCR-aided selection of a rice line containing the Rf-1 gene which is involved in restoration of the cytoplasmic male sterility显示文摘 | Norio Ichikawa Noaki Kishimoto Akiko Inagaki Atsushi Nakamura Yoko Koshino Yumi Yokozeki Masaaki Oka Shiro Samoto Hiromori Akagi Kenichi Higo Choyu Shinjyo Tatsuhito Fujimura Hiroaki Shimada | 1997 | Molecular Breeding1997，，3： | 1 |
| 16 | Up - regulation by progesterone of proliferating cell nuclear antigen and epider- mal growth factor expression in human uterine leiomyoma显示文摘 | Shimomura Y Matsuo H Samoto T | 1998 | J Clin Endoerinol Metah1998，83，： | 1 |
| 17 | Increased expression of Bacl - 2 protein in human uterine leiomyoma and its up - regulation by progestion 显示文摘 | Matsuo H Maruo T Samoto T | 1997 | Clin endoerinol Metab1997，82，1： | 1 |
| 18 | Prostaglandin E2 stimulates bone sialoprotein (BSP) expression through cAMP and fi- breblast growth factor 2 response elements in the proximal promoter of the rat BSP gene 显示文摘 | Samoto H Shimizu E Matsuda - Honjyo Y | 2003 | J Biol Chem2003，31，28： | 1 |
| 19 | Comparative results of conservative treatments for isolated anterior talofibular ligament (ATFL) injury and injury to both the ATFL and calcaneofi bular ligament of the ankle as assessed by subtalar arthrography显示文摘 | Samoto N Sugimoto K Takaoka T | 2007 | J Orthop Sci2007，12，1： | 1 |
| 20 | Diagnosis of discoid lateral meniscus of the knee on MR imaging 显示文摘 | Samoto N Kozuma M Tokuhisa T | 2002 | Magn Reson Imaging2002，20，： | 1 |
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