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| 1 | Intratumoral dendritic cell vaccin ation elicits potent tumoricidal im munity against malignant glioma in rats显示文摘Dendritic cells(DC)are attractive candidates for innovative cancer immunotherapy by virtu e of their ability to function as powe rful antigen presenting cells and elicit potent antitumor cytotoxic immune r esponses.With the aim of generating antitumor immunity,the authors sought to enhance in vivo tum or antigen presentation by using an i ntratumoral DC vaccination strateg y in the setting of partially irradiated intracranial brain tumo rs.Fisher rats,implanted with 9L gliomas in the right corpus striatum,w ere treated with freshly cultured,unpulsed syngeneic DC inoculated directly into the tumor bed.Intracranially inoculated DCs were found to drain to ipsilateral deep cervical lymph nodes.This was a ssociated with increased local and s ystemic antitumor cytoxicity,as evidenced by robust infiltration of treated tumors with CD4and CD8T ce lls as well as by increased IFN-gamma protein and message levels in in vitr o restimulated splenic lymphocytes.DC therapy resulted in prolonged survival and immunity to s ubsequent intracranial tumor re-ch allenge.These results demonstrate the viability of intratumoral DC vaccination as an effectiv e therapeutic strategy for intracra nial glioma. | Ehtesham M Kabos P Gutierrez MA Samoto K Black KL Yu JS | 2003 | 癌症2003，22，7： | 8 |
| 2 | Treatment of intracranial glioma with in situ interferon-gamma and tumor necrosis factor-alpha gene transfer 显示文摘 | Ehtesham M Samoto K Kabos P | 2002 | Cancer Gene Ther2002，9，11： | 1 |
| 3 | Colon cacer screening by a new test:a prospective study of asymptomatic population显示文摘 | Samoto K Muratani M Ogawa J | 1993 | Proc AM ASSOC Cancer Res1993，32，： | 1 |
| 4 | Expression of vascular endothelial growth factor and its possible relation with neovascularization in human brain tumors 显示文摘 | Ikezaki K Ono M | 1995 | Cancer Res1995，55，： | 1 |
| 5 | Diagnosis of discoid lateral meniscus of the knee on MR imaging 显示文摘 | Samoto N Kozuma M Tokuhisa T | 2002 | Magn Reson Imaging2002，20，1： | 1 |
| 6 | Improvement of the off-flavor of soy protein isolate by removing oil-body associated proteins and polar lipids显示文摘 | SAMOTO M MIYAZAKI C KANAMOR J | 1998 | Bioscience Biotechnology Biochemistry1998，62，5： | 1 |
| 7 | Abundant proteins associated with lecithin in soy protein isolate显示文摘 | Samoto M Maebuchi M Miyazaki C | 2007 | Food Chemistry2007，102，1： | 1 |
| 8 | Expression of vascμlar endothelial growth factor and its possible relation with neovascμlarization in human brain tumors显示文摘 | Samoto K Ikozaki K Ono M | 1995 | Cancer Res1995，55，： | 1 |
| 9 | Substantially complete removal of three major allergenic soybean proteins (Gly m Bd 30K,Gly m Bd 28K,and the alpha subunit of conglycinin) from soy protein by using a mutant soybean,Tohoku 124显示文摘 | Samoto M Fukuda Y Takahashi K | 1997 | Biosci Biotech Biochem1997，61，： | 1 |
| 10 | Abundant proteins associated with lecithin in soy protein isolate显示文摘 | SAMOTO M MAEBUCHI M CHIAKI M | 2007 | Agric Food Chem2007，102，1： | 1 |
| 11 | Substantially complete removal of the 34 kDa allergenic soybean protein,Gly m Bd 30K,from soy milk of a mutant lacking with alpha-and alpha′-subunits of conglycinin显示文摘 | Samoto M Takahashi K Fukuda Y | 1996 | Biosci Biotech Biochem1996，60，： | 1 |
| 12 | Diagnosis of discoid lateral meniscus of the knee on MR imaging 显示文摘 | Samoto N Kozuma M Tokuhisa T | 2002 | Magn Reson Imaging2002，20，： | 1 |
| 13 | Soybean allergens and hypoallergenic soybean products 显示文摘 | Ogawa T Samoto M Takahashi K | 2000 | Nutritional Science and Vitaminology2000，46，6： | 1 |
| 14 | Abundant proteins associated with lecithin in soy protein isolate显示文摘 | Samoto M Maebuchi M Miyazaki C etal | 2007 | Food Chemistry2007，102，1： | 1 |
| 15 | Expression of vascular endothelial growth factor and its possible relation with neovascularization in human brain tumors显示文摘 | SAMOTO K IKEZAKI K ONO M | 1995 | Cancer Res1995，55，5： | 1 |
| 16 | Substantial complete removal of three major allergenic soybean proteins ( Gly m Bd 30K,Gly m Bd 28K,and the a - subunit of -conglycinin )from soy protein by using a mutant soybean, Tohoku 124 显示文摘 | Samoto M Fukuda Y Takahashi K | 1997 | Biosci Biotech Biochem1997，61，12： | 1 |
| 17 | Soybean allergens and hypoallergenic soybean products 显示文摘 | Ogawa T Samoto M Takahashi Koji | 2000 | Nutr Sci Vitamino2000，46，： | 1 |
| 18 | Expression of vascular endothelial growth factor and its possible relation with neovascularization in human brain tumors 显示文摘 | Samoto K Ikozaki K Ono M | 1995 | Cancer Res1995，55，： | 1 |
| 19 | Soybean allergens and hypoallergenic soybean products显示文摘 | Ogawa A Samoto M Takahashi K | 2000 | Journal of Nutrition Science Vitaminol2000，46，： | 1 |
| 20 | Expression of vascular endothelial growth factor and its possible relation with neovascularzation in human brain tumors显示文摘 | Samoto K Ikezaki K Ono M | 1995 | Cancer Res1995，55，5： | 1 |
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