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| 1 | Role of autophagy in the pathophysiology of nonalcoholic fatty liver disease:A controversial issue显示文摘Autophagy is a mechanism involved in cellular homeostasis under basal and stressed conditions delivering cytoplasmic content to the lysosomes for degradation to macronutrients.The potential role of autophagy in disease is increasingly recognised and investigated in the last decade.Nowadays it is commonly accepted that autophagy plays a role in the hepatic lipid metabolism.Hence,dysfunction of autophagy may be an underlying cause of non-alcoholic fatty liver disease.However,controversy of the exact role of autophagy in the lipid metabolism exists:some publications report a lipolytic function of autophagy,whereas others claim a lipogenic function.This review aims to give an update of the present knowledge on autophagy in the hepatic lipid metabolism,hepatic insulin resistance,steatohepatitis and hepatic fibrogenesis. | Wilhelmus J Kwanten Wim Martinet Peter P Michielsen Sven M Francque | 2014 | World Journal of Gastroenterology2014，20，23： | 17 |
| 2 | Extended surgical resection for xanthogranulomatous cholecystitis mimicking advanced gallbladder carcinoma: A case report and review of literature显示文摘Xanthogranulomatous 胆汁(XGC ) 是胆囊的破坏煽动性的疾病,很少包含邻近的机关并且模仿国王先进胆囊癌。诊断在病理学的检查以后仅仅通常是可能的。46 42 岁的女人被指我们包含肝核,正确的肝脑叶,恰好结肠的弯曲,和十二指肠的怀疑的胆囊癌症的中心。刷细胞学获得了由内视镜后退胆管造影术(ERC ) 出现了高级发育异常。病人经历了团的在团体切除术,由正确叶切除术,正确的半结肠切除术,和部分十二指肠的切除术组成。出人意料地揭示的病理学的检查一 XGC.Only,为有邻近的机关的直接参与的 XGC 的扩大外科的切除术的六个案例到目前为止被报导了。在这些情况中,与癌给 XGC 的可能的共存,恶意不能被排除,甚至在细胞学和 intraoperative 冰冻切片调查以后。在结论,由于源于在另外的方面上包围机关的高度好攻击的煽动性的侵略的一个方面和可能的复杂并发症上的胆囊癌的差的预后,它似乎这些案例应该被当作恶性瘤直到不那样证明。临床医生们应该包括 XGC 在之中可能微分在肝核群众诊断。 | Antonino Spinelli Guido Schumacher Andreas Pascher Enrique Lopez-Hanninen Hussain Al-Abadi Christoph Benckert Igor M Sauer Johann Pratschke Ulf P Neumann Sven Jonas Jan M Langrehr Peter Neuhaus | 2006 | World Journal of Gastroenterology2006，12，14： | 13 |
| 3 | Assessment of stable coronary artery disease by cardiovascular magnetic resonance imaging: Current and emerging techniques显示文摘Coronary artery disease(CAD) is a leading cause of death and disability worldwide. Cardiovascular magnetic resonance(CMR) is established in clinical practice guidelines with a growing evidence base supporting its use to aid the diagnosis and management of patients with suspected or established CAD. CMR is a multi-parametric imaging modality that yields high spatial resolution images that can be acquired in any plane for the assessment of global and regional cardiac function, myocardial perfusion and viability, tissue characterisation and coronary artery anatomy, all within a single study protocol and without exposure to ionising radiation. Advances in technology and acquisition techniques continue to progress the utility of CMR across a wide spectrum of cardiovascular disease, and the publication of large scale clinical trials continues to strengthen the role of CMR in daily cardiology practice. This article aims to review current practice and explore the future directions of multi-parametric CMR imaging in the investigation of stable CAD. | James RJ Foley Sven Plein John P Greenwood | 2017 | World Journal of Cardiology2017，9，2： | 6 |
| 4 | Gut microbiota disturbance during antibiotic therapy: a multi-omic approach显示文摘 | Ana Elena Pérez-Cobas María José Gosalbes Anette Friedrichs Henrik Knecht Alejandro Artacho Kathleen Eismann Wolfgang Otto David Rojo Rafael Bargiela Martin von Bergen Sven C Neulinger Carolin D?umer Femke-Anouska Heinsen Amparo Latorre Coral Barbas Jana | 2013 | Gut2013，，11： | 2 |
| 5 | Enhancement of intrinsic tumor cell radiosensitivity induced by a selective cyclooxygenase-2 inhibitor显示文摘 | Sven P Luke M | 2000 | Clin Cancer Res2000，，6： | 1 |
| 6 | IL-2-and CD25-dependent immunoregulatory mechanisms in the homeostasis of T cell subsets 显示文摘 | Sven L Carsten K Giuseppe P | 2009 | Journal of Allergy and Clinical Immunology2009，123，4： | 1 |
| 7 | On the assembly of experimental setups in virtual laboratory environments 显示文摘 | Chang Chenhung Eshe P Sven K | 2008 | ASME International Mechanical Engineering Congress and Exposition Proceedings2008，7，： | 1 |
| 8 | Bovine β-defensins: identification and characterization of novel bovine β-defensin genes and their expression in mammarygland tissue显示文摘 | Susanne R Kay E Sven P | 2004 | Mammalian Genome2004，15，10： | 1 |
| 9 | New developments in the diagnosis of bloodstream infections显示文摘 | Remco P H Peters Michiel A van Agtmael Sven A Danner | 2004 | Infectious Diseases2004，4，12： | 1 |
| 10 | Designing Payments for Environmental Services in Theory and Practice: An Overview of the Issues 显示文摘 | Stefanie E Stefano P Sven W | 2008 | Ecological Economics2008，65，： | 1 |
| 11 | Rapid diagnosis of bacterial meningitis by real-time PCR and fluorescence in situ hybridization显示文摘 | SVEN P ANDREAS E BARBARA S | 2005 | J Clin Microbiol2005，43，7： | 1 |
| 12 | IL -2 and CD25 dependentimmunoregulatory mechanisms in the homeostasis of T - cell subsets显示文摘 | Sven L Carsten K Giuseppe P | 2009 | J Allergy and Clin Immunol2009，123，4： | 1 |
| 13 | Enhancement of intrinsic tumor cell radiosensitivity induced by a selective cyclooxygenase-2 inhibitor 显示文摘 | CORDULA P P SVEN P | 2000 | Clin Cancer Res2000，6，6： | 1 |
| 14 | Management and outcome of patients with combined bile duct and hepatic arterial injuries after laparoscopic cholecystectomy显示文摘 | Sven C Schmidt Ulz Settmacher Jan M Langrehr P Neuhaus | 2004 | Surgery2004，，6： | 1 |
| 15 | RFID tags for identifying and verifying agrochemicals in food traceability systems显示文摘 | Peers Sven Gasparin C P Blackburn D W K etal | 2009 | Precision Agric2009，，10： | 1 |
| 16 | The sensitivity and specificity of nonmydriatic digital stereoscopic retinal Imagine in detecting diabetic retinopathy显示文摘 | JEHANARA A THOMAS P SVEN ERIC B | 2006 | Diabetes Care2006，29，10： | 1 |
| 17 | Shallow drilling of seafloor hydrothermal systems using the BGS rockdrill 显示文摘 | Sven P Peter M H Thomas K | 2005 | Marine Georesources and Geotechnology2005，，23： | 1 |
| 18 | Methods for Testing and Analyzing Lithium-Ion Battery Cells intended for Heavy-Duty Hybrid Electric Vehicles显示文摘 | Svens P | 2014 | 2014，，： | 1 |
| 19 | Random Forests as a Tool for Ecohydrological Distribution Modelling显示文摘 | Jan P Bernard D B Niko E C V Roeland S Sven D Piet D B Willy H | 2007 | Ecological Modelling2007，207，24： | 1 |
| 20 | MR ima-ging, single-photon emission CT, and neurocognitive performance after mild traumatic brain injury显示文摘 | PAUL A M H SVEN Z S MARINUS J P G | 2001 | American Journal of Neuroradiology2001，22，3： | 1 |
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