维普中文期刊产品整合服务
823篇 您的检索式:作者名="SUBHASH"
    题名 作者 年代 出处 被引量
1玉米产量及构成因子主效和上位性QTL的全基因组扫描分析显示文摘在此前构建的含174个分子标记的连锁图基础上,新增31个分子标记,并利用统计分析的方法对基因型数据进行检测,剔除基因型明显有误的数据,构建了共包含205个分子标记,平均间距为11.2 cM,覆盖玉米全基因组10条染色体的分子标记连锁图.基于统计学的基因型数据检测,能显著提高连锁图构建的准确性.结合一年两点6个重复的田间实验,利用软件R/qtl进行主效和上位性QTL分析,同时利用多区间作图法(MIM)验证主效QTL和主效QTL互作的真实性和位置.通过MIM方法,检测到控制产量、行粒数、行数和百粒重的主效QTL分别为5,5,7和5个,分别能解释35.3%,37.4%(含1个互作QTL),61.5%和39.7%的遗传变异;除行粒数的2个QTL之间存在显著性互作之外,其他性状的主效QTL之间都没有检测到显著性互作存在.同时,还检测到24个上位性互作QTL,这些OTL涉及的位点几乎分布于所有10条染色体.这些互作QTL以主效QTL与无显著效应基因座之间的互作居多,对所有4个性状而言比例接近三分之二.这也说明主效QTL除了单独起作用之外还可以通过与其他没有显著效应的基因座之间互作来影响性状表达.结果表明,上位性QTL在玉米产量性状的遗传中可能与主效QTL一样也起着重要的作用.严建兵 汤华 黄益勤 郑用琏 Subhash Chander 李建生 2006科学通报2006,51,12:23
2Comparative clinical trial of S-pantoprazole versus racemic pantoprazole in the treatment of gastro-esophageal reflux disease显示文摘AIM: To compare the effi cacy and tolerability of S-pan- toprazole (20 mg once a day) versus racemic Panto- prazole (40 mg once a day) in the treatment of gastro- esophageal reflux disease (GERD). METHODS: This multi-centre, randomized, double-blind clinical trial consisted of 369 patients of either sex suf- fering from GERD. Patients were randomly assigned to receive either one tablet (20 mg) of S-pantoprazole once a day (test group) or 40 mg racemic pantoprazole once a day (reference group) for 28 d. Patients were evaluated for reduction in baseline on d 0, GERD symptom score on d 14 and 28, occurrence of any adverse effect during the course of therapy. Gastrointestinal (GI) endoscopy was performed in 54 patients enrolled at one of the study centers at baseline and on d 28. RESULTS: Signifi cant reduction in the scores (mean and median) for heart burn (P < 0.0001), acid regurgitation (P < 0.0001), bloating (P < 0.0001), nausea (P < 0.0001) and dysphagia (P < 0.001) was achieved in both groups on d 14 with further reduction on continuing the therapy till 28 d. There was a statistically signifi cant difference in the proportion of patients showing improvement in acid regurgitation and bloating on d 14 and 28 (P = 0.004 for acid regurgitation; P = 0.03 for bloating) and heart burn on d 28 (P = 0.01) between the two groups, with a higher proportion in the test group than in the refer- ence group. Absolute risk reductions for heartburn/acid regurgitation/bloating were approximately 15% on d 14 and 10% on d 28. The relative risk reductions were 26%-33% on d 14 and 15% on d 28. GI endoscopy showed no signifi cant difference in healing of esophagitis (P = 1) and gastric erosions (P = 0.27) between the two groups. None of the patients in either group reported any adverse effect during the course of therapy.CONCLUSION: In GERD, S-pantoprazole (20 mg) is more effective than racemic pantoprazole (40 mg) in improving symptoms of heartburn, acid regurgitation, bloating and equally effective in healing esophagitis and gastric erosions. The relative risk reduction is 15%-33%. Both drugs are safe and well tolerated.Vikas G Pai Nitin V Pai Hemant P Thacker Jaisingh K Shinde Vijay P Mandora Subhash S Erram 2006World Journal of Gastroenterology2006,12,37:19
3部分充液罐车内液体晃动的瞬态响应分析显示文摘针对部分充液罐车转向或制动过程中罐体内液体的晃动问题,建立了液罐车内液体晃动的三维力学模型,通过与准静态模型以及罐体内液体晃动的试验结果进行对比,验证了模型的有效性。研究了防波板的几何参数(开孔的大小、形状及位置等)对液体瞬态晃动时的载荷转移及晃动力的影响。评估了防波板不同的几何参数下,作用在罐体端面以及单个防波板上的力。发现了在中等或高充液比的情况下,在防波板和罐体端面或者相邻防波板之间的密闭空间将产生很大的空气压力。研究结果表明,防波板的几何参数对液体载荷的载荷转移量、晃动产生的作用力以及俯仰力矩均有很大的影响。空气压力可以减小液体的载荷的纵向转移量,从而抑制液体的晃动,提高车辆的制动性能。王琼瑶 蒋开洪 Subhash Rakheja 上官文斌 2018振动与冲击2018,37,17:15
4Bitter melon: a panacea for inflammation and cancer显示文摘Nature is a rich source of medicinal plants and their products that are useful for treatment of various diseases and disorders. Momordica charantia, commonly known as bitter melon or bitter gourd, is one of such plants known for its biological activities used in traditional system of medicines. This plant is cultivated in all over the world, including tropical areas of Asia, Amazon, east Africa, and the Caribbean and used as a vegetable as well as folk medicine. All parts of the plant, including the fruit, are commonly consumed and cooked with different vegetables, stir-fried, stuffed or used in small quantities in soups or beans to give a slightly bitter flavor and taste. The plant is reported to possess anti-oxidant, anti-inflammatory, anti-cancer, anti-diabetic, anti-bacterial, anti-obesity, and immunomodulatory activities. The plant extract inhibits cancer cell growth by inducing apoptosis, cell cycle arrest, autophagy and inhibiting cancer stem cells. The plant is rich in bioactive chemical constituents like cucurbitane type triterpenoids, triterpene glycosides, phenolic acids, flavonoids, essential oils, saponins, fatty acids, and proteins. Some of the isolated compounds(Kuguacin J, Karaviloside XI, Kuguaglycoside C, Momordicoside Q-U, Charantin, α-eleostearic acid) and proteins(α-Momorcharin, RNase MC2, MAP30) possess potent biological activity. In the present review, we are summarizing the anti-oxidant, anti-inflammatory, and anti-cancer activities of Momordica charantia along with a short account of important chemical constituents, providing a basis for establishing detail biological activities of the plant and developing novel drug molecules based on the active chemical constituents.Prasad R. Dandawate Dharmalingam Subramaniam Subhash B. Padhye Shrikant Anant 2016Chinese Journal of Natural Medicines2016,14,2:14
5双超越离合器式电磁馈能阻尼器原型机试验测试与分析显示文摘在对双超越离合器式电磁馈能阻尼器的前期研究基础上,试制了该阻尼器的原型机,并对谐波激励下原型机的频谱响应特性和阻尼响应特性进行了分析。通过对原型机的测试,证明了该结构方案的可行性,同时还证实了利用转动惯量分力,在被动模式下实现'high-low'半主动阻尼方法的正确性,并为展开对双超越离合器结构的进一步研究奠定了基础。于长淼 王伟华 Subhash Rakheja 王庆年 2012吉林大学学报(工学版)2012,42,2:13
6高油和普通玉米自交系类胡萝卜素和生育酚含量的比较分析显示文摘建立了利用高效液相色谱法同时测定玉米籽粒类胡萝卜素和生育酚各组分含量的技术体系,分析了112份黄色胚乳玉米自交系的类胡萝卜素和生育酚含量,其中包括32份高油自交系和80份在生产上广泛应用的普通玉米自交系。结果表明,不同自交系间存在广泛的变异,各组分含量变幅最大的是α-生育酚,含量相差达162倍;变幅最小的是δ-生育酚,含量相差也接近4倍。类胡萝卜素各组分含量在高油和普通玉米自交系之间并没有显著差异,但普通玉米的变异范围更为广泛;高油玉米生育酚各组分含量显著高于普通玉米,其中γ-生育酚、α-生育酚和总生育酚含量的均值分别是普通玉米均值的2.4、2.5和2.4倍。尽管供试的高油玉米材料仅32份,但其生育酚的某些组分比普通玉米具有更广泛的遗传变异。这为进一步的玉米高油、高维生素A原、高维生素E,即'三高'品质成分育种提供了有益参考。周毅 付志远 李青 徐淑兔 CHANDER Subhash 杨小红 李建生 严建兵 2009作物学报2009,35,11:12
7罐体横截面形状对液罐车侧倾稳定性影响分析显示文摘提出液罐车罐体截面形状设计方法,研究液罐横截面形状对半挂式液罐车侧倾稳定性影响,分析广泛使用的圆形截面液罐、改进的椭圆截面液罐及锥形截面液罐特点。提出两种改进的液罐截面形状,给出液罐中液体晃动产生的侧向力、侧倾力矩准静态条件的计算方法。以6轴半挂式液罐车为例计算液罐车模型的侧翻阈值、变道时横向负载转移及侧倾角响应峰值。基于准静态、动态两类指标分析该半挂式液罐车装载不同截面液罐时侧倾稳定特性。结果表明,两种改进的液罐截面形状可在较大充液比范围内提高液罐车侧倾稳定性。陈益苞 Subhash Rakheja 上官文斌 2016振动与冲击2016,35,6:12
8The role and significance of Magnesium in modern day research-A review显示文摘Magnesium is one of the largely available elements in the earth’s crust. It has a low structural density with high specific strength. This unique material property has forced an increase in the use of magnesium and its alloys in various applications pertaining to industrial sector,automobiles, aerospace and biomedical. Since magnesium is a highly reactive metal, it is prone to higher rate of corrosion as compared to its counterparts. Thus, it is essential to analyze the corrosion behavior of magnesium and its alloys in its applications. An appropriate process is to be followed in the design and development of magnesium alloys which overcome the limitations of magnesium and enhance the desired material properties in accordance to their applications. This review paper summarizes the importance of magnesium and its material properties. The influence of various alloying elements on the mechanical properties of magnesium is reviewed. The broad classification of Mg alloys and their behavioral trends are detailed. The corrosion behavior of magnesium and the influence of corrosion products on the material characteristics of magnesium, in aqueous medium, are discussed. The manufacturing techniques of magnesium alloys along with the secondary techniques are also covered. The various applications and the limitations of magnesium in these applications are covered. A complete section is dedicated towards detailing the recent trends of magnesium(Mg) alloys, i.e., the biodegradable nature and applications of Mg alloys. The influence of biocorrosion on Mg alloys and techniques to overcome it have been deliberated. This paper provides a thorough review on recent developments of magnesium with respect to engineering applications.S V Satya Prasad S B Prasad Kartikey Verma Raghvendra Kumar Mishra Vikas Kumar Subhash Singh 2022Journal of Magnesium and Alloys2022,10,1:11
9Virological course of hepatitis A virus as determined by real time RT-PCR: Correlation with biochemical, immunological and genotypic profiles显示文摘瞄准:承担肝炎 A 的分析,并且相关病毒的负担,丙氨酸 aminotransferase (中高音) ,和有病毒血的持续时间的病毒的遗传型有控制调停房间的免疫的 CD4 (+)/ CD8 (+) 淋巴细胞人口的这些参数。方法:房间计数用用荧光在乙二胺四乙酸小瓶收集的新鲜全血被执行激活的房间 sorter。肝炎 A 病毒(HAV ) RNA 从血浆液被提取,抄录进 cDNA 并且由实时聚合酶链反应确定了并且是 genotyped 的颠倒。结果:在 11 个病人之中, 10 能完全被分析。这些, 3 有严重尖锐肝炎(s -- 啊) 并且剩余物有自我限制尖锐肝炎 A (啊哈) ,在第 4 d 上与有暴发性的疾病(脑病等级 IV ) 的一个病人一起死。中高音水平在啊哈两个都是显著地更高的(1070.9 +/- 894.3;P = 0.0014 ) 并且 s -- 啊(1713.9 +/- 886.3;P = 0.001 ) 与正常控制相比(23.6 +/- 7.2 ) 。在 s 的前凝血酶时间 -- 啊病人(21.0 +/- 2.0;P = 0.02 ) 比在啊哈显著地高(14.3 +/- 1.1;P = 0.44 ) 。在啊哈病人的 CD4 (+)/CD8 (+) 比率(1.17 +/- 0.11;P = 0.22 ) 并且 s -- 啊(0.83 +/- 0.12;P = 0.0002 ) 比在正常健康控制(1.52 ) 看低。有的自我限制盒子达到顶点在分析的开始的病毒的负担当时在 s -- 啊病人这发生在第 15 或第 30 d。在敏锐、严格的组,一耐心的各个属于遗传型 IA,与仍然是 8 个盒子属于遗传型 IIIA。唯一的暴发性的肝的失败大小写属于遗传型 IA。在自我限制感染的全部功课期间收集的 HAV 病毒的负担和中高音价值直接为 s 被相关,但是这不是事实 -- 啊病人。结论:基于小规模的研究, s 的固执地更高的病毒的负担 -- 啊可能由于减少的细胞免疫和溶血。病毒血的持续时间依赖于主人,当病毒的遗传型没在 AVH 和 s 的临床的结果有明显的角色 -- 啊盒子。Zahid Hussain Bhudev C Das Syed A Husain Sunil K Polipalli Tanzeel Ahmed Nargis Begum Subhash Medhi Alice Verghese Mohammad Raish Apiradee Theamboonlers Yong Poovorawan Premashis Kar 2006World Journal of Gastroenterology2006,12,29:10
10Emergence of nanotechnology in the oil and gas industry:Emphasis on the application of silica nanoparticles显示文摘The application of nanotechnology in the oil and gas industry is on the rise as evidenced by the number of researches undertaken in the past few years.The quest to develop more game-changing technologies that can address the challenges currently facing the industry has spurred this growth.Several nanoparticles,of different sizes and at different concentrations,have been used in many investigations.In this work,the scope of the study covered the application of nanotechnology in drilling and hydraulic fracturing fluids,oilwell cementing,enhanced oil recovery(which includes transport study,and foam and emulsion stability),corrosion inhibition,logging operations,formation fines control during production,heavy oil viscosity reduction,hydrocarbon detection,methane release from gas hydrates,and drag reduction in porous media.The observed challenges associated with the use of nanoparticles are their stability in a liquid medium and transportability in reservoir rocks.The addition of viscosifier was implemented by researchers to ensure stability,and also,surface-treated nanoparticles have been used to facilitate stability and transportability.For the purpose of achieving better performance or new application,studies on synergistic effects are suggested for investigation in future nanotechnology research.The resulting technology from the synergistic studies may reinforce the current and future nanotechnology applications in the oil and gas industry,especially for high pressure and high temperature(HPHT)applications.To date,majority of the oil and gas industry nanotechnology publications are reports of laboratory experimental work;therefore,more field trials are recommended for further advancement of nanotechnology in this industry.Usually,nanoparticles are expensive;so,it will be cost beneficial to use the lowest nanoparticles concentration possible while still achieving an acceptable level of a desired performance.Hence,optimization studies are also recommended for examination in future nanotechnology research.Muili Feyisitan Fakoya Subhash Nandlal Shah 2017Petroleum2017,3,4:10
11带弹性膜的部分充液罐车罐体内液体横向晃动的瞬态响应分析显示文摘针对部分充液罐车转向过程中罐体内液体的晃动问题,提出了一种新型抑制液体晃动的阻尼装置:弹性膜。建立了相应的罐体内带弹性膜的流体-弹性膜耦合动力学模型,并通过实验验证了模型的有效性。通过计算仿真方法研究了弹性膜及其预应力的大小对液体瞬态时的晃动力和载荷转移量的影响。研究结果表明:弹性膜能限制液体的晃动幅值,从而减小液体晃动时对罐体壁面产生的侧倾力矩;弹性膜增大了液体横向晃动的固有频率,使液体横向晃动的固有频率远离了液罐车的紧急转向频率,从而避免了液罐车紧急转向时共振现象的发生。王琼瑶 Subhash Rakheja 上官文斌 2019振动与冲击2019,38,5:10
12Anti-inflammatory and anti-arthritic activity of type-A procyanidine polyphenols from bark of Cinnamomum zeylanicum in rats显示文摘Type-A procyanidine polyphenols(TAPP)are reported to have immunomodulatory and anti-inflammatory potential in vitro.The objective of present work is to evaluate potential of TAPP extracted from Cinnamon(Cinnamomum zeylanicum)bark in animal models of inflammation and rheumatoid arthritis in rats.Carrageenan-induced rat paw edema(CPE)and adjuvant induced established arthritis(AIA),in rats were used as the experimental models for inflammation and arthritis respectively.Analgesic activity was evaluated in Randall–Selitto assay in AIA rats.TAPP showed significant anti-inflammatory effect at dose of 4,8 and 25 mg/kg,p.o.but not at 2 mg/kg,p.o.dose in CPE model.The dose of 8 mg/kg,p.o.was selected for the evaluation of anti-arthritic activity in AIA model.TAPP(8 mg/kg,p.o.,daily from day-12 to day-21)treatment in established arthritic rats showed significant reversal of changes induced in AIA with respect to body weight drop(cachexia),ankle diameter,arthritic score,serum C-reactive protein(CRP)levels.Moreover,TAPP was found to be non-ulcerogenic as compared to AIA control rats.However,TAPP did not show analgesic effect on AIA-induced pain as seen in Randall–Selitto assay.In conclusion,TAPP showed disease-modifying potential in animal models of inflammation and arthritis in rats.©2013 Beijing Academy of Food Sciences.Production and hosting by Elsevier B.V.All rights reserved.Sachin Vetal Subhash L.Bodhankar Vishwaraman Mohan Prasad A.Thakurdesai 2013Food Science and Human Wellness2013,2,2:8
13动力总成悬置系统隔振率的计算方法显示文摘基于动力总成为刚体的假设,根据A车型悬上、悬下点的加速度的实测值,建立了动力总成激励力的识别方法。由动力总成激励力计算结果,和悬下点IPI数据,给出了悬上、悬下点加速度和悬置的隔振率的计算方法。B车型的动力总成与A车型相同,但悬置系统与车身不同。由建立的模型计算了B车型悬置系统悬上点加速度,与实测值进行了对比分析,证明了动力总成激励力识别模型的有效性。利用识别的动力总成激励力,和测试得到的B车型悬下点的IPI参数,计算得到了B车型各个悬置的隔振率,与实测结果的对比分析证明了该研究建立的悬置隔振率计算方法的有效性。该研究识别得到的动力总成的激励力,可以用于评价动力总成振动。根据动力总成的激励力和悬下点的IPI参数,计算得到的悬置的隔振率,为悬置系统的优化设计提供了分析方法。罗国海 上官文斌 秦武 李利平 叶必军 Subhash Rakheja 2019振动与冲击2019,38,14:8
14Naringin ameliorates acetic acid induced colitis through modulation of endogenous oxido-nitrosative balance and DNA damage in rats显示文摘The aim of this study was to evaluate the effect of naringin on experimentally induced inflammatory bowel disease in rats.Naringin(20,40 and 80 mg/kg) was given orally for 7 days to Wistar rats before induction of colitis by intrarectal instillation of 2 mL of 4%(v/v) acetic acid solution.The degree of colonic mucosal damage was analyzed by examining mucosal damage,ulcer area,ulcer index and stool consistency.Intrarectal administration of 4%acetic acid resulted in significant modulation of serum alkaline phosphatase,lactate dehydrogenase,superoxide dismutase(SOD),glutathione(GSH),malondialdehyde(MDA) and myeloperoxidase(MPO) content along with colonic nitric oxide(NO),xanthine oxidase(XO) level and protein carbonyl content in the colonic tissue as well as in blood.Naringin(40 and 80 mg/kg) exerted a dose dependent(P < 0.05) ameliorative effect,as it significantly increased hematological parameter as well as colonic SOD and GSH.There was a significant(P < 0.05)and dose dependant inhibition of macroscopical score,ulcer area along with colonic MDA,MPO activity by the7 days of pretreatment of naringin(40 and 80 mg/kg).Biochemical studies revealed a significant(P < 0.05) dose dependant inhibition in serum alkaline phosphatase(ALP) and lactate dehydrogenase(LDH) levels by pretreatment of naringin.Increased levels of colonic NO,XO,protein carbonyl content and DNA damage were also significantly decreased by naringin pretreatment.The findings of the present investigation propose that naringin has an anti-inflammatory,anti-oxidant and anti-apoptotic potential effect at colorectal sites as it modulates the production and expression of oxidative mediators such as MDA,MPO,NO and XO,thus reducing DNA damage.Venkatashivam Shiva Kumar Anuchandra Ramchandra Rajmane Mohammad Adil Amit Dattatraya Kandhare Pinaki Ghosh Subhash Laxman Bodhankar 2014The Journal of Biomedical Research2014,28,2:8
15一种基于聚合酶链式反应检测SNP的方法显示文摘SNP是具有广泛利用潜力的第3代分子标记,本文旨在开发一种利用PCR技术快速检测SNP的方法。设计思路是:根据已知SNP位点设计2条特异正向引物,其最后一个碱基分别与已知SNP的2个碱基相同,同时在1条引物的5′端添加1段20 bp左右的其他物种的特异序列(如细菌DNA序列),然后选择1条合适的反向引物;最后同时加入3条引物,通过梯度PCR选择合适的退火温度进行PCR反应。利用这一方法成功将玉米的ZDS基因定位在玉米第7染色体短臂7.02 Bin。这种检测SNP的方法设计简单,费用低廉,尤其适合SNP标记的分子标记连锁图构建或者基因定位。郑艳萍 Chander Subhash 杨小红 周俊青 李建生 严建兵 2006中国农业大学学报2006,11,3:7
16Development of polyvinylpyrrolidone/paclitaxel self-assemblies for breast cancer显示文摘The goal of this investigation was to develop and demonstrate a polymer/paclitaxel selfassembly(PTX-SA) formulation. Polymer/PTX-SAs were screened based on smaller size of formulation using dynamic light scattering analysis. Additionally, fluorescence microscopy and flow cytometry studies exhibited that polyvinylpyrrolidone(PVP)-based PTX-SAs(PVP/PTX-SAs) had superior cellular internalization capability in MCF7 and MDA-MB-231 breast cancer cells. The optimized PVP/PTXSAs exhibited less toxicity to human red blood cells indicating a suitable formulation for reducing systemic toxicity. The formation of PVP and PTX self-assemblies was confirmed using fluorescence quenching and transmission electron microscopy which indicated that the PVP/PTX-SAs were spherical in shape with an average size range of 53.81 nm as detected by transmission electron microscopy(TEM).FTIR spectral analysis demonstrates incorporation of polymer and paclitaxel functional groups in PVP/PTX-SAs. Both proliferation(MTS) and clonogenic(colony formation) assays were used to validate superior anticancer activity of PVP/PTX-SAs in breast cancer cells over paclitaxel. Such superior anticancer activity was also demonstrated by downregulation of the expression of pro-survival protein(Bcl-x L), upregulation of apoptosis-associated proteins(Bid, Bax, cleaved caspase 7, and cleaved PARP)and β-tubulin stabilization. These results support the hypothesis that PVP/PTX-SAs improved paclitaxel delivery to cancer cells.Pallabita Chowdhury Prashanth K.B.Nagesh Sheema Khan Bilal B.Hafeez Subhash C.Chauhan Meena Jaggi Murali M.Yallapu 2018Acta Pharmaceutica Sinica B2018,8,4:7
17Identification of unconditional and conditional QTL for oil, protein and starch content in maize显示文摘Oil, protein and starch are key chemical components of maize kernels. A population of 245 recombinant inbred lines(RILs) derived from a cross between a high-oil inbred line, By804, and a regular inbred line, B73, was used to dissect the genetic interrelationships among oil, starch and protein content at the individual QTL level by unconditional and conditional QTL mapping. Combined phenotypic data over two years with a genetic linkage map constructed using 236 markers, nine, five and eight unconditional QTL were detected for oil, protein and starch content, respectively. Some QTL for oil, protein and starch content were clustered in the same genomic regions and the direction of their effects was consistent with the sign of their correlation. In conditional QTL mapping, 37(29/8) unconditional QTL were not detected or showed reduced effects, four QTL demonstrated similar effects under unconditional and conditional QTL mapping, and 17 additional QTL were identified by conditional QTL mapping. These results imply that there is a strong genetic relationship among oil, protein and starch content in maize kernels. The information generated in the present investigation could be helpful in marker-assisted breeding for maize varieties with desirable kernel quality traits.Yuqiu Guo Xiaohong Yang Subhash Chander Jianbing Yan Jun Zhang Tongming Song Jiansheng Li 2013The Crop Journal2013,1,1:7
18Observer-based Adaptive Optimal Control for Unknown Singularly Perturbed Nonlinear Systems With Input Constraints显示文摘This paper introduces an observer-based adaptive optimal control method for unknown singularly perturbed nonlinear systems with input constraints. First, a multi-time scales dynamic neural network(MTSDNN) observer with a novel updating law derived from a properly designed Lyapunov function is proposed to estimate the system states. Then, an adaptive learning rule driven by the critic NN weight error is presented for the critic NN, which is used to approximate the optimal cost function. Finally, the optimal control action is calculated by online solving the Hamilton-Jacobi-Bellman(HJB)equation associated with the MTSDNN observer and critic NN.The stability of the overall closed-loop system consisting of the MTSDNN observer, the critic NN and the optimal control action is proved. The proposed observer-based optimal control approach has an essential advantage that the system dynamics are not needed for implementation, and only the measured input/output data is needed. Moreover, the proposed optimal control design takes the input constraints into consideration and thus can overcome the restriction of actuator saturation.Simulation results are presented to confirm the validity of the investigated approach.Zhijun Fu Wenfang Xie Subhash Rakheja Jing Na 2017IEEE/CAA Journal of Automatica Sinica2017,4,1:6
19剪式悬架座椅等效刚度阻尼的计算与分析显示文摘推导了座椅悬架的等效刚度和等效阻尼,建立了座椅-座椅悬架-人体耦合二自由度理论简化模型,计算分析了系统的传递函数。在建立的模型的基础上,讨论了座椅悬架结构的变化对系统响应的影响,讨论了弹簧倾角、阻尼器倾角,以及连杆的长度和倾角对座椅悬架系统等效刚度及其变化、等效阻尼和传递函数的影响。所建立的理论模型,可为进行座椅悬架结构的优化设计提供分析模型。水奕洁 Subhash Rakheja 上官文斌 2016振动与冲击2016,35,19:5
20Preoperative radiotherapy versus selective postoperative chemoradiotherapy in patients with rectal cancer (MRC CR07 and NCIC-CTG C016): a multicentre, randomised trial显示文摘David Sebag-Montefiore Richard J Stephens Robert Steele John Monson Robert Grieve Subhash Khanna Phil Quirke Jean Couture Catherine de Metz Arthur Sun Myint Eric Bessell Gareth Griffiths Lindsay C Thompson Mahesh Parmar 2009The Lancet2009,,9666:5
返回顶部 每页显示:
共42页 首页 上一页 第1页 下一页 末页 /42 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费