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| 1 | Micro RNAs in colorectal cancer:Role in metastasis and clinical perspectives显示文摘Colorectal cancer(CRC)is the third most common malignancy and the third leading cause of cancer related deaths in the United States.Almost 90%of the patients diagnosed with CRC die due to metastases.Micro RNAs(mi RNAs)are evolutionarily conserved molecules that modulate the expression of their target genes post-transcriptionally,and they may participate in various physiological and pathological processes including CRC metastasis by influencing various factors in the human body.Recently,the role mi RNAs play throughout the CRC metastatic cascade has gain attention.Many studies have been published to link them with CRC metastasis.In this review,we will briefly discuss metastatic steps in the light of mi RNAs,along with their target genes.We will discuss how the aberration in the expression of mi RNAs leads to the formation of CRC by effecting the regulation of their target genes.As mi RNAs are being exploited for diagnosis,prognosis,and monitoring of cancer and other diseases,their high tissue specificity and critical role in oncogenesis make them new biomarkers for the diagnosis and classification of cancer as well as for predicting patients’outcome.Mi RNA signatures have been identified for many human tumors including CRC,and mi RNA-based therapies to treat cancer have been emphasized lately.These will also be discussed in this review. | Shan Muhammad Kavanjit Kaur Rui Huang Qian Zhang Paviter Kaur Hamza Obaid Yazdani Muhammad Umar Bilal Jiang Zheng Liu Zheng Xi-Shan Wang | 2014 | World Journal of Gastroenterology2014，20，45： | 13 |
| 2 | Retreatment of a patient who presented with synchronous multiple primary colorectal carcinoma: report of a case显示文摘It is well known that one-stage resection of synchronous multiple primary colorectal carcinoma is an ideal choice if the patient's physical condition is not bad. Detailed examination of the whole intestinal tract is very important for patients with colorectal cancer, which could prevent patients from receiving repeat treatment to a great extent. We present a case report of a patient with synchronous primary colorectal cancer. Because pre-or intra-operative examination is not sufficient at his first consultation, the patient had undergone multiple operations after receiving chemotherapy, radiotherapy and intestinal stent insertion, which results in peritoneal adhesions formation. The preoperative placement of prophylactic ureteral catheters facilitated recognition of ureters in operation that assure the prevention of ureteral injuries. If not aware of the importance of detailed preoperative examination and standardized treatment can lead to wrong treatment as in this case. Prophylactic ureteral catheters might assist in their immediate recognition. | Zheng Jiang Shan Muhammad Xishan Wang | 2013 | Chinese Journal of Cancer Research2013，25，4： | 6 |
| 3 | Highly efficient and selective photocatalytic dehydrogenation of benzyl alcohol for simultaneous hydrogen and benzaldehyde production over Ni-decorated Zn_(0.5)Cd_(0.5)S solid solution显示文摘Photocatalytic conversion of solar energy into hydrogen and high value-added fine chemicals has attracted increasing attention. Herein, we demonstrate an efficient photocatalytic system for simultaneous hydrogen evolution and benzaldehyde production by dehydrogenation of benzyl alcohol over Nidecorated Zn_(0.5)Cd_(0.5)S solid solution under visible light. The photocatalytic system shows an excellent hydrogen production rate of 666.3 μmol h^(-1) with high stability. The optimal apparent quantum yield of52.5% is obtained at 420 nm. This noble-metal-free photocatalytic system displays much higher activity than pure Zn_(0.5)Cd_(0.5)S and Pt-loaded Zn_(0.5)Cd_(0.5)S solid solution. Further studies reveal that the metallic Ni nanocrystals play an important role in accelerating the separation of photogenerated charge carriers and the subsequent cleavage of α-C–H bond during dehydrogenation of benzyl alcohol. | Lei Zhang Daochuan Jiang Rana Muhammad Irfan Shan Tang Xin Chen Pingwu Du | 2019 | Journal of Energy Chemistry2019，28，3： | 5 |
| 4 | Assessing soil nitrous oxide emission as affected by phosphorus and nitrogen addition under two moisture levels显示文摘Agricultural soils are deficient of phosphorus(P) worldwide. Phosphatic fertilizers are therefore applied to agricultural soils to improve the fertility and to increase the crop yield. However, the effect of phosphorus application on soil N_2O emissions has rarely been studied. Therefore, we conducted a laboratory study to investigate the effects P addition on soil N_2O emissions from P deficient alluvial soil under two levels of nitrogen(N) fertilizer and soil moisture. Treatments were arranged as follows: P(0 and 20 mg P kg^(–1)) was applied to soil under two moisture levels of 60 and 90% water filled pore space(WFPS). Each P and moisture treatment was further treated with two levels of N fertilizer(0 and 200 mg N kg^(–1) as urea). Soil variables including mineral nitrogen(NH_4^+-N and NO_3~–-N), available P, dissolved organic carbon(DOC), and soil N_2O emissions were measured throughout the study period of 50 days. Results showed that addition of P increased N_2O emissions either under 60% WFPS or 90% WFPS conditions. Higher N_2O emissions were observed under 90% WFPS when compared to 60% WFPS. Application of N fertilizer also enhanced N_2O emissions and the highest emissions were 141 μg N_2O kg^(–1) h^(–1) in P+N treatment under 90% WFPS. The results of the present study suggest that P application markedly increases soil N_2O emissions under both low and high soil moisture levels, and either with or without N fertilizer application. | Bashir Ullah Muhammad Shaaban HU Rong-gui ZHAO Jin-song LIN Shan | 2016 | Journal of Integrative Agriculture2016，15，12： | 2 |
| 5 | Surface texture evaluation of additively manufactured metallic cellular scaffolds for acetabular implants using X.ray computed tomography显示文摘The surface topography of acetabular implants plays a key role in providing cell attachment and proliferation.The measurement and characterisation of the surface texture of the cellular scaffold layer on the acetabular cup are very difficult due to the 3D nature of scaffold geometry.It is proposed to use X-ray computed tomography(XCT)to measure the surface texture of an electron beam melting-produced titanium acetabular cup.The surface texture of its cellular scaffold is evaluated using the newly developed 3D surface texture parameters,which allows surface characterisation on 3D triangular mesh surfaces.Four commonly used height parameters,i.e.the arithmetical mean height Sa,the root mean square height Sq,the skewness Ssk and the kurtosis Sku,are calculated from surface patches extracted from the XCT scanned triangular mesh surface.In addition,the surface peak density and pit density,which are more related to cell communication and proliferation,are estimated based on the 3D watershed segmentation.The Wolf pruning with an empirical threshold 12μm is used to control the over-segmentation. | Shan Lou Luca Pagani Wenhan Zeng Muhammad U.Ghori Xiangqian Jiang Paul J.Scott | 2019 | Bio-Design and Manufacturing2019，2，2： | 1 |
| 6 | Isolation and charac- terization of the Shiga toxin gene (stx ) - bearing Escherichia coli 0157 and non - O157 from retail meats in Shandong Province, Chi- na, and characterization of the O157 - derived stx2 phages 显示文摘 | Koitabashi T Shan C Muhammad K | 2008 | J Food Prot2008，71，4： | 1 |
| 7 | Study on accuracy of 1 - degree i)EM versus topographic complexity using GIS zonal analysis显示文摘 | Jie Shan Muhammad Zaheer and Ejaz Hussain | 2000 | Journal of Surveying Engineering2000，129，2： | 1 |
| 8 | Mass propagation of Bougainvillea spectabilis through shoot tip culture 显示文摘 | SHAN S T ZAMIR R MUHAMMAD T | 2006 | Pak J Bot2006，38，4： | 1 |
| 9 | Factors affecting the distribution of microplastics in soils of China显示文摘Microplastics(MPs)are found worldwide in high abundance,posing a potential threat to ecosystems.Despite the ubiquity of MPs in the environment,very little is known about the regional distribution of MPs and underlying factors affecting this distribution in the field,which likely include human activity,but also features of the environment itself.Here,out of a total of 1157 datapoints investigated in 53 Chinese studies,9.68%datapoints were removed as outliers in the heterogeneity analysis.This review revealed that the abundance of MPs was highly heterogeneous.In addition,microplastic(MP)distribution maps based on China demonstrated that the highest abundance of MPs tended to occur near large rivers and central land affected by the intersection of two monsoons.The model-fitting and previous studies showed that MP abundance in China was correlated with longitude,agricultural mulching film usage per capita,temperature,and precipitation.However,due to the heterogeneity of MPs and the low matching degree between the current environmental data and the sampling points,this pattern was not as evident as reported in any single study.Factors affecting the distribution of MPs can not be captured by linear relationships alone,and systematic selection of suitable environmental factors and further model optimization are needed to explore the cause of MP pollution in soil.Overall,this review revealed an uneven distribution of MPs and serves as a reference for model prediction to assess and control plastic pollution in natural soil environments. | Yin Liu Matthias CRillig Quan Liu Jingjing Huang Muhammad Amjad Khan Xiaohui Li Qin Liu Qingqing Wang Xuesong Su Linyi Lin Yang Bai Genmao Guo Yi Huang Yong Sik Ok Shan Hu Junfeng Wang Honggang Ni Qing Huang | 2023 | Frontiers of Environmental Science & Engineering2023，17，9： | 1 |
| 10 | Numerical Simulation for Bioconvection of Unsteady Stagnation Point Flow of Oldroyd-B Nanofluid with Activation Energy and Temperature-Based Thermal Conductivity Past a Stretching Disk显示文摘A mathematical modeling is explored to scrutinize the unsteady stagnation point flow of Oldroyd-B nanofluid under the thermal conductivity and solutal diffusivity with bioconvection mechanism.Impacts of Joule heating and Arrhenius activation energy including convective boundary conditions are studied,and the specified surface temperature and constant temperature of wall(CTW)are discussed.The consequences of thermal conductivity and diffusivity are also taken into account.The flow is generated through stretchable disk geometry,and the behavior of non-linear thermal radiation is incorporated in energy equation.The partial differential equations governing the fluid flow in the structure is reduced into dimensionless nonlinear ODEs by applying suitable similarity variables.The obtained system of non-dimensional nonlinear ODEs is treated numerically with the help of bvp4c solver in Matlab under shooting algorithm.The impact of various prominent parameters on velocity profile,thermal profile,volumetric nanoparticle concentration and microorganism distribution is depicted in graphical form.The numerical outcomes for skin friction coefficient,heat transfer rate,Sherwood number as well as microorganism density number versus various parameters are listed in the tables.The results show that fluid velocity is reduced by increasing buoyancy ratio parameter,while the fluid flow increases with mixed convective parameter.The temperature profile is enhanced with the amount of nonlinear thermal radiation and temperature dependent thermal conductivity.Furthermore,concentration profiles of nanoparticles have opposite behavior for Brownian motion coefficient and thermophoresis diffusion parameter,and it is noticed that by varying Peclet number the microorganisms profile is declined.The proposed study is useful to control and optimize heat transfer in industrial applications. | Muhammad Sami Rashad Haihu Liu Shan Ali Khan | 2022 | Computer Modeling in Engineering & Sciences2022，，1： | 0 |
| 11 | 磁性多孔四氧化三铁/聚(甲基丙烯酸甲酯-co-二乙烯基苯)微球的制备、表征及其去除罗丹明B的应用研究(英文)显示文摘目的:通过悬浮聚合法合成含有Fe3O4磁性核的多孔聚合物微球,研究不同单体比例、致孔剂类型及用量对所合成磁性微球的形貌影响以发现最佳反应条件,最终将所合成的磁性多孔微球应用于从水溶液中去除阳离子染料罗丹明B,并证明成功。方法:1.通过改进的悬浮聚合法合成了磁性多孔四氧化三铁/聚(甲基丙烯酸甲酯-co-二乙烯基苯);2.通过红外及能谱表征产物的组成,使用扫描电镜及透射电镜表征产物的表面及内部形貌,通过热失重分析表征产物的聚合物包覆率,通过X射线粉末衍射表征产物的晶型,使用压汞法表征产物的多孔性及孔结构,利用超导量子干涉仪测定产物的磁性能;3.通过紫外分光光度法验证产物对于罗丹明B的吸附及其效果。结论:1.通过改进的悬浮聚合法成功合成磁性多孔四氧化三铁/聚(甲基丙烯酸甲酯-co-二乙烯基苯);2.表面聚合物的包覆并不影响四氧化三铁的晶型;3.产物的形貌及孔结构受到单体甲基丙烯酸甲酯与致孔剂二乙烯基苯的比例、致孔剂类型及用量等多方面影响;4.所合成的产物对于罗丹明B有很好的吸附效果,同时具有很好的重复利用性;5.所合成的聚合物在废水中重金属的去除、酶固定化、药物的靶向释放及生物分离等方面都有潜在应用价值。 | Jie SHAN Li WANG Hao-jie YU Yu-lei TAI Muhammad AKRAM | 2015 | Journal of Zhejiang University-Science A(Applied Physics & Engineering)2015，16，8： | 0 |
| 12 | Feasibility and physics potential of detecting ^(8)B solar neutrinos at JUNO显示文摘The Jiangmen Underground Neutrino Observatory(JUNO)features a 20 kt multi-purpose underground liquid scintillator sphere as its main detector.Some of JUNO's features make it an excellent location for^8B solar neutrino measurements,such as its low-energy threshold,high energy resolution compared with water Cherenkov detectors,and much larger target mass compared with previous liquid scintillator detectors.In this paper,we present a comprehensive assessment of JUNO's potential for detecting^8B solar neutrinos via the neutrino-electron elastic scattering process.A reduced 2 MeV threshold for the recoil electron energy is found to be achievable,assuming that the intrinsic radioactive background^(238)U and^(232)Th in the liquid scintillator can be controlled to 10^(-17)g/g.With ten years of data acquisition,approximately 60,000 signal and 30,000 background events are expected.This large sample will enable an examination of the distortion of the recoil electron spectrum that is dominated by the neutrino flavor transformation in the dense solar matter,which will shed new light on the inconsistency between the measured electron spectra and the predictions of the standard three-flavor neutrino oscillation framework.IfDelta m^(2)_(21)=4.8times10^(-5);(7.5times10^(-5))eV^(2),JUNO can provide evidence of neutrino oscillation in the Earth at approximately the 3sigma(2sigma)level by measuring the non-zero signal rate variation with respect to the solar zenith angle.Moreover,JUNO can simultaneously measureDelta m^2_(21)using^8B solar neutrinos to a precision of 20% or better,depending on the central value,and to sub-percent precision using reactor antineutrinos.A comparison of these two measurements from the same detector will help understand the current mild inconsistency between the value of Delta m^2_(21)reported by solar neutrino experiments and the KamLAND experiment. | Angel Abusleme Thomas Adam Shakeel Ahmad Sebastiano Aiello Muhammad Akram Nawab Ali Fengpeng An Guangpeng An Qi An Giuseppe Andronico Nikolay Anfimov Vito Antonelli Tatiana Antoshkina Burin Asavapibhop João Pedro Athayde Marcondes de André Didier Auguste Andrej Babic Wander Baldini Andrea Barresi Eric Baussan Marco Bellato Antonio Bergnoli Enrico Bernieri David Biare Thilo Birkenfeld Sylvie Blin David Blum Simon Blyth Anastasia Bolshakova Mathieu Bongrand Clément Bordereau Dominique Breton Augusto Brigatti Riccardo Brugnera Riccardo Bruno Antonio Budano Max Buesken Mario Buscemi Jose Busto Ilya Butorov Anatael Cabrera Hao Cai Xiao Cai Yanke Cai Zhiyan Cai Antonio Cammi Agustin Campeny Chuanya Cao Guofu Cao Jun Cao Rossella Caruso Cédric Cerna Jinfan Chang Yun Chang Pingping Chen Po-An Chen Shaomin Chen Shenjian Chen Xurong Chen Yi-Wen Chen Yixue Chen Yu Chen Zhang Chen Jie Cheng Yaping Cheng Alexander Chepurnov Davide Chiesa Pietro Chimenti Artem Chukanov Anna Chuvashova Gérard Claverie Catia Clementi Barbara Clerbaux Selma Conforti Di Lorenzo Daniele Corti Salvatore Costa Flavio Dal Corso Christophe De La Taille Jiawei Deng Zhi Deng Ziyan Deng Wilfried Depnering Marco Diaz Xuefeng Ding Yayun Ding Bayu Dirgantara Sergey Dmitrievsky Tadeas Dohnal Georgy Donchenko Jianmeng Dong Damien Dornic Evgeny Doroshkevich Marcos Dracos Frédéric Druillole Shuxian Du Stefano Dusini Martin Dvorak Timo Enqvist Heike Enzmann Andrea Fabbri Lukas Fajt Donghua Fan Lei Fan Can Fang Jian Fang Marco Fargetta Anna Fatkina Dmitry Fedoseev Vladko Fekete Li-Cheng Feng Qichun Feng Richard Ford Andrey Formozov Amélie Fournier Haonan Gan Feng Gao Alberto Garfagnini Alexandre Göttel Christoph Genster Marco Giammarchi Agnese Giaz Nunzio Giudice Franco Giuliani Maxim Gonchar Guanghua Gong Hui Gong Oleg Gorchakov Yuri Gornushkin Marco Grassi Christian Grewing Maxim Gromov Vasily Gromov Minghao Gu Xiaofei Gu Yu Gu Mengyun Guan Nunzio Guardone Maria Gul Cong Guo Jingyuan Guo Wanlei Guo Xinheng Guo Yuhang Guo Paul Hackspacher Caren Hagner Ran Han Yang Han Miao He Wei He Tobias Heinz Patrick Hellmuth Yuekun Heng Rafael Herrera Daojin Hong YuenKeung Hor Shaojing Hou Yee Hsiung Bei-Zhen Hu Hang Hu Jianrun Hu Jun Hu Shouyang Hu Tao Hu Zhuojun Hu Chunhao Huang Guihong Huang Hanxiong Huang Qinhua Huang Wenhao Huang Xingtao Huang Yongbo Huang Jiaqi Hui Wenju Huo Cédric Huss Safeer Hussain Antonio Insolia Ara Ioannisian Daniel Ioannisyan Roberto Isocrate Kuo-Lun Jen Xiaolu Ji Xingzhao Ji Huihui Jia Junji Jia Siyu Jian Di Jiang Xiaoshan Jiang Ruyi Jin Xiaoping Jing Cécile Jollet Jari Joutsenvaara Sirichok Jungthawan Leonidas Kalousis Philipp Kampmann Li Kang Michael Karagounis Narine Kazarian Amir Khan Waseem Khan Khanchai Khosonthongkee Patrick Kinz Denis Korablev Konstantin Kouzakov Alexey Krasnoperov Svetlana Krokhaleva Zinovy Krumshteyn Andre Kruth Nikolay Kutovskiy Pasi Kuusiniemi Tobias Lachenmaier Cecilia Landini Sébastien Leblanc Frederic Lefevre Liping Lei Ruiting Lei Rupert Leitner Jason Leung Demin Li Fei Li Fule Li Haitao Li Huiling Li Jiaqi Li Jin Li Kaijie Li Mengzhao Li Nan Li Nan Li Qingjiang Li Ruhui Li Shanfeng Li Shuaijie Li Tao Li Weidong Li Weiguo Li Xiaomei Li Xiaonan Li Xinglong Li Yi Li Yufeng Li Zhibing Li Ziyuan Li Hao Liang Hao Liang Jingjing Liang Jiajun Liao Daniel Liebau Ayut Limphirat Sukit Limpijumnong Guey-Lin Lin Shengxin Lin Tao Lin Jiajie Ling Ivano Lippi Fang Liu Haidong Liu Hongbang Liu Hongjuan Liu Hongtao Liu Hu Liu Hui Liu Jianglai Liu Jinchang Liu Min Liu Qian Liu Qin Liu Runxuan Liu Shuangyu Liu Shubin Liu Shulin Liu Xiaowei Liu Yan Liu Alexey Lokhov Paolo Lombardi Claudio Lombardo Kai Loo Chuan Lu Haoqi Lu Jingbin Lu Junguang Lu Shuxiang Lu Xiaoxu Lu Bayarto Lubsandorzhiev Sultim Lubsandorzhiev Livia Ludhova Fengjiao Luo Guang Luo Pengwei Luo Shu Luo Wuming Luo Vladimir Lyashuk Qiumei Ma Si Ma Xiaoyan Ma Xubo Ma Jihane Maalmi Yury Malyshkin Fabio Mantovani Francesco Manzali Xin Mao Yajun Mao Stefano MMari Filippo Marini Sadia Marium Cristina Martellini Gisele Martin-Chassard Agnese Martini Davit Mayilyan Axel Müller Ints Mednieks Yue Meng Anselmo Meregaglia Emanuela Meroni David Meyhöfer Mauro Mezzetto Jonathan Miller Lino Miramonti Salvatore Monforte Paolo Montini Michele Montuschi Nikolay Morozov Pavithra Muralidharan Massimiliano Nastasi Dmitry VNaumov Elena Naumova Igor Nemchenok Alexey Nikolaev Feipeng Ning Zhe Ning Hiroshi Nunokawa Lothar Oberauer Juan Pedro Ochoa-Ricoux Alexander Olshevskiy Domizia Orestano Fausto Ortica Hsiao-Ru Pan Alessandro Paoloni Nina Parkalian Sergio Parmeggiano Teerapat Payupol Yatian Pei Nicomede Pelliccia Anguo Peng Haiping Peng Frédéric Perrot Pierre-Alexandre Petitjean Fabrizio Petrucci Luis Felipe Piñeres Rico Oliver Pilarczyk Artyom Popov Pascal Poussot Wathan Pratumwan Ezio Previtali Fazhi Qi Ming Qi Sen Qian Xiaohui Qian Hao Qiao Zhonghua Qin Shoukang Qiu Muhammad Rajput Gioacchino Ranucci Neill Raper Alessandra Re Henning Rebber Abdel Rebii Bin Ren Jie Ren Taras Rezinko Barbara Ricci Markus Robens Mathieu Roche Narongkiat Rodphai Aldo Romani Bedřich Roskovec Christian Roth Xiangdong Ruan Xichao Ruan Saroj Rujirawat Arseniy Rybnikov Andrey Sadovsky Paolo Saggese Giuseppe Salamanna Simone Sanfilippo Anut Sangka Nuanwan Sanguansak Utane Sawangwit Julia Sawatzki Fatma Sawy Michaela Schever Jacky Schuler Cédric Schwab Konstantin Schweizer Dmitry Selivanov Alexandr Selyunin Andrea Serafini Giulio Settanta Mariangela Settimo Muhammad Shahzad Vladislav Sharov Gang Shi Jingyan Shi Yongjiu Shi Vitaly Shutov Andrey Sidorenkov FedorŠimkovic Chiara Sirignano Jaruchit Siripak Monica Sisti Maciej Slupecki Mikhail Smirnov Oleg Smirnov Thiago Sogo-Bezerra Julanan Songwadhana Boonrucksar Soonthornthum Albert Sotnikov Ondrej Sramek Warintorn Sreethawong Achim Stahl Luca Stanco Konstantin Stankevich DušanŠtefánik Hans Steiger Jochen Steinmann Tobias Sterr Matthias Raphael Stock Virginia Strati Alexander Studenikin Gongxing Sun Shifeng Sun Xilei Sun Yongjie Sun Yongzhao Sun Narumon Suwonjandee Michal Szelezniak Jian Tang Qiang Tang Quan Tang Xiao Tang Alexander Tietzsch Igor Tkachev Tomas Tmej Konstantin Treskov Andrea Triossi Giancarlo Troni Wladyslaw Trzaska Cristina Tuve Stefan van Waasen Johannes van den Boom Guillaume Vanroyen Nikolaos Vassilopoulos Vadim Vedin Giuseppe Verde Maxim Vialkov Benoit Viaud Cristina Volpe Vit Vorobel Lucia Votano Pablo Walker Caishen Wang Chung-Hsiang Wang En Wang Guoli Wang Jian Wang Jun Wang Kunyu Wang Lu Wang Meifen Wang Meng Wang Ruiguang Wang Siguang Wang Wei Wang Wenshuai Wang Xi Wang Xiangyue Wang Yangfu Wang Yaoguang Wang Yi Wang Yifang Wang Yuanqing Wang Yuman Wang Zhe Wang Zheng Wang Zhimin Wang Zongyi Wang Apimook Watcharangkool Lianghong Wei Wei Wei Yadong Wei Liangjian Wen Christopher Wiebusch Steven Chan-Fai Wong Bjoern Wonsak Diru Wu Fangliang Wu Qun Wu Wenjie Wu Zhi Wu Michael Wurm Jacques Wurtz Christian Wysotzki Yufei Xi Dongmei Xia Yuguang Xie Zhangquan Xie Zhizhong Xing Benda Xu Donglian Xu Fanrong Xu Jilei Xu Jing Xu Meihang Xu Yin Xu Yu Xu Baojun Yan Xiongbo Yan Yupeng Yan Anbo Yang Changgen Yang Huan Yang Jie Yang Lei Yang Xiaoyu Yang Yifan Yang Haifeng Yao Zafar Yasin Jiaxuan Ye Mei Ye Ugur Yegin Frédéric Yermia Peihuai Yi Xiangwei Yin Zhengyun You Boxiang Yu Chiye Yu Chunxu Yu Hongzhao Yu Miao Yu Xianghui Yu Zeyuan Yu Chengzhuo Yuan Ying Yuan Zhenxiong Yuan Ziyi Yuan Baobiao Yue Noman Zafar Andre Zambanini Pan Zeng Shan Zeng Tingxuan Zeng Yuda Zeng Liang Zhan Feiyang Zhang Guoqing Zhang Haiqiong Zhang Honghao Zhang Jiawen Zhang Jie Zhang Jingbo Zhang Peng Zhang Qingmin Zhang Shiqi Zhang Tao Zhang Xiaomei Zhang Xuantong Zhang Yan Zhang Yinhong Zhang Yiyu Zhang Yongpeng Zhang Yuanyuan Zhang Yumei Zhang Zhenyu Zhang Zhijian Zhang Fengyi Zhao Jie Zhao Rong Zhao Shujun Zhao Tianchi Zhao Dongqin Zheng Hua Zheng Minshan Zheng Yangheng Zheng Weirong Zhong Jing Zhou Li Zhou Nan Zhou Shun Zhou Xiang Zhou Jiang Zhu Kejun Zhu Honglin Zhuang Liang Zong Jiaheng Zou | 2021 | Chinese Physics C2021，45，2： | 0 |
| 13 | Numerical computation of Brownian motion and thermophoresis effects on rotational micropolar nanomaterials with activation energy显示文摘The current article investigates the numerical study of the micropolar nanofluid flow through a 3D rotating surface.This communication may manipulate for the aim such as the delivery of the drug,cooling of electronic chips,nanoscience and the fields of nanotechnology.The impact of heat source/sink is employed.Brownian motion and thermophoresis aspects are discussed.The rotating sheet with the impacts of Darcy-Forchheimer law is also scrutinized.Furthermore,the influence of activation energy is analyzed in the current article.The numerical analysis is simplified with the help of befitted resemblance transformations.The succor of the shooting algorithm with built-in solver bvp4c MATLAB software is used for the numerical solution of nonlinear transformed equations.The consequences of different physical factors on the physical engineering quantities and the subjective fields were examined and presented.According to outcomes,it can be analyzed that the flow profile declined with the rotational parameter.It is observed that angular velocity diminishes via a larger porosity parameter.Furthermore,the temperature gradient is declined via a larger magnitude of the Prandtl number.The heat transfer is enhanced in the occurrence of Brownian motion.The activations energy parameter causes an increment in the volumetric concentration field.Moreover,the local Nusselt number is reduced via a greater estimation of the porosity parameter. | Hassan Waqas Shan Ali Khan Bagh Ali Dong Liu Taseer Muhammad Enran Hou | 2023 | Propulsion and Power Research2023，12，3： | 0 |
| 14 | Anthropological analyses of 30 insertion/deletion autosomal markers in five major ethnic groups of Pakistan显示文摘We investigated the forensic efficacy of the 30 insertion/deletion(Indel)markers included in the Qiagen Investigator■DIPplex kit in 529 Pakistani individuals from five major subpopulations in Pakistan(Punjabi,Pashtun,Sindhi,Saraiki,and Baloch).In the Sindhi population,the distribution of HLD81 and HLD97 alleles deviated from Hardy-Weinberg equilibrium after Bonferroni correction.The combined match probability ranged from 2.0E-12(Pashtun and Baloch)to 1.0E-12(Sindhi),and the mean paternity exclusion power varied from 0.995(Punjabi,Sindhi,and Saraiki)to 0.996(Pashtun and Baloch).The high combined power of discrimination(0.99999999999997)and low combined match probability(1.7E-12)for all subpopulations studied support the utility of the 30 Indel markers for forensic identification in the studied subpopulations.The allele frequencies of the Indel markers in the Pakistani subpopulations were compared with those from 18 other populations.The results show that the populations clustered according to geography.The subpopulations investigated in this work showed a close genetic relationship with others from Pakistan,as well as with South Central Asian and Middle Eastern populations.The results suggest that the Investigator■DIPplex kit can be useful as a supplementary tool for human identification in the five Pakistani subpopulations investigated in this study. | Muhammad Adnan Shan Julie Mechlenborg Rebecca Roen Claus Bosting Niels Morling | 2022 | Forensic Sciences Research2022，7，2： | 0 |
| 15 | Efficacy of bioactive compounds of Chaihu(Radix Bupleuri Chinensis)on glaucomatous optic atrophy through interleukin-6/hypoxia inducible factor-1αsignal pathway显示文摘OBJECTIVE:To investigate the bioactive compounds of Chaihu(Radix Bupleuri Chinensis)(RB)on glaucomatous optic atrophy(GOA),and to study the pharmacological mechanism.METHODS:We collected information on the bioactive compounds of RB from the Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform(TCMSP).Targets related to bioactive compounds and GOA were also obtained.Gene Ontology(GO),Kyoto Encyclopedia of Genes and Genomes(KEGG)pathway and network analyses were performed to investigate the potential mechanism of RB against GOA.Subsequently,the main bioactive compounds of RB and targets of GOA were docked by Autodock software.Moreover,a GOA model of retinal ganglion cells(RGCs)induced by cobalt chloride was established to verify the effect of RB on GOA.RESULTS:There were 17 main bioactive compounds and 46 key targets were screened as potential players in GOA.The compound-target network mainly contained 17 compounds and 46 corresponding targets,and the key targets consisted of interleukin-6(IL-6),hypoxia inducible factor-1α(HIF1A),Caspase-3,estrogen receptor alpha(ESR1),MYC proto-oncogene(MYC),and vascular endothelial growth factor A(VEGFA).Forty-nine significantly enriched GO terms,and 134 KEGG signaling pathways were identified(P<0.05),including HIF-1,tumor necrosis factor,VEGF,prolaction,and other signaling pathways.Molecular docking results showed that the main bioactive compounds of RB exhibited the strongest binding activity with IL-6.Furthermore,experimental validation showed that the RB extract inhibited the activity and promoted apoptosis of RGCs in a dose-dependent manner.The RB extract also suppressed the expression of Bax,Caspase-3,and Caspase-9 and regulated malonaldehyde,superoxide dismutase,and glutathione peroxide by inhibiting the IL-6/HIF-1αsignaling pathway.CONCLUSIONS:The present study provided insights into the mechanism of RB on GOA.RB mainly reverses GOA by inhibiting the IL-6/HIF-1αsignaling pathway. | YANG Xirui ZHAO Hui SHAN Muhammad DONG Feixue ZHANG Dandan WANG Jixue YUAN Xingxing | 2023 | Journal of Traditional Chinese Medicine2023，43，6： | 0 |
| 16 | Retained placenta: Do we have any option?显示文摘Retained placenta is a known cause of post-partum haemorrhage and maternal mortality. A recent systemic review has confirmed that the incidence of retained placenta had increased all over the world, which is more common in developed countries. Failure of retroplacental myometrium contraction is the main cause of retained placenta. Maternal age greater than 35 years, grandmultipara, preterm labor, history of previous retained placenta, and caesarean section were the risk factors for retained placenta. Manual removal of the placenta has been the treatment of choice. Attempts had been made by clinician and researchers to find a safe, effective and reliable method to avoid the need for surgical intervention. The efficacy and safety of prostaglandin, nitroglycerin or acupuncture in the management of retained placenta are yet to be further evaluated. Nonetheless, till date only intraumbilical vein oxytocin has been studied extensively but with varied success. More randomized clinical trials are needed to address this issue. However, if immediate manual placenta removal service is unavailable, a trial of intra-umbilical vein oxytocin 100 IU at a totalvolume of at least 40 m L while preparing for transfer to a tertiary center or theatre may result in spontaneous expulsion of the placenta. | Pei Shan Lim Nor Azlin Mohamed Ismail Nur Azurah Abd Ghani Nirmala Chandralega Kampan Aqmar Suraya Sulaiman Beng Kwang Ng Kah Teik Chew Abdul Kadir Abdul Karim Muhammad Abdul Jamil Mohd Yassin | 2014 | World Journal of Obstetrics and Gynecology2014，3，3： | 0 |
| 17 | Effect of fineness of ash on pozzolanic properties and acid resistance of sugarcane bagasse ash replaced cement mortars显示文摘This paper addresses the potential use of Sugar Cane Bagasse Ash(SCBA)as a pozzolanic material for partial cement replacement in concrete mixtures.Cement mortars containing SCBA having five different particle size distributions at a replacement rate of 20%by weight were used to study the chemical and physical pozzolanic properties of SCBA.The durability of SCBA replaced mortars was also evaluated.SCBA with 0%retained on sieve No.325 was used to replace 20%by weight of cement and create mortar specimens that were subjected to sulfuric acid attack of varying concentrations(1%–3%by weight of water).The tested samples were observed to check visual distortion,mass loss,and compressive strength loss at 1,7,14,28,and 56 d of acidic exposure,and the results were compared to those for the control sample,that was lime water cured,at the same ages.The SCBA sets were found to meet the requirements for pozzolan class N specified by ASTM C 618.Mortars containing SCBA with 0%or 15%retention produced better compressive strength than the control mortars after 28 d.Additionally,X-ray fluorescence and X-ray diffraction analysis showed that the SCBA had favorable chemical properties for a pozzolanic material.Furthermore,SCBA replaced samples at all ages showed improved resistance against acidic attack relative to that of the control mortars.Maximum deterioration was seen for 3%concentrated solution.This study’s findings demonstrated that SCBA with an appropriate fineness could be used as a pozzolanic material,consistently with ASTM C 618. | Shan E ALI Rizwan AZAM Muhammad Rizwan RIAZ Mohamed ZAWAM | 2022 | Frontiers of Structural and Civil Engineering2022，16，10： | 0 |
| 18 | Comparative Study of the Effects of Nano ZnO and CuO on the Biodegradation,Biocompatibility,and Antibacterial Properties of Micro-arc Oxidation Coating of Magnesium Alloy显示文摘This research systematically examined the degradation,antibacterial effects,and biocompatibility of micro-arc oxidation(MAO)coatings with nano CuO and ZnO on extruded Mg alloys.Both copper(Cu)and Zinc(Zn)possess antibacterial properties.The findings demonstrated that adding ZnO will appreciably reduce the degradation rate of MAO-coating alloy due to the self-sealing micro holes.CuO+MAO coating exhibited excellent antibacterial performance,with an antibacterial rate of over 90%within 6 h co-cultured with Staphylococcus aureus.Similarly,the antibacterial rate of ZnO+MAO coating reached 90%after 12 h co-culture.Cytotoxicity test using MG63 cell indicated that the incorporation of CuO and ZnO did not notably affect the cell viability rate of the coating.Moreover,after 14 days of culture,the CuO+MAO and ZnO+MAO coated samples exhibited higher alkaline phosphatase(ALP)activity than the MAO-coated and uncoated samples,suggesting favorable osteogenic properties. | Ying Shen Xianfeng Shan Iniobong P.Etim Muhammad Ali Siddiqui Yang Yang Zewen Shi Xuping Su Junxiu Chen | 2024 | Acta Metallurgica Sinica(English Letters)2024，37，2： | 0 |
| 19 | Micro RNAs in colorectal cancer显示文摘Introduction In 2008 over 1.2 million new cases along with 608 700 estimated CRC-associated deaths have occurred.In China,where it is now the third most common malignancy and the fifth leading cause of cancer-related death,the incidence of CRC is still increasing even with the improvements in the standard of living and changes in lifestyle.Despite improvements in | Shan Muhammad Kavanjit Kaur 王锡山 | 2013 | 中华结直肠疾病电子杂志2013，2，5： | 0 |
| 20 | Mild hyperthermia-enhanced chemo-photothermal synergistic therapy using doxorubicin-loaded gold nanovesicles显示文摘Gold nanovesicles(GVs) with unique plasmonic property and large cavity hold great potential as a stimuli-responsive nanocarrier to deliver drugs for efficient tumor chemotherapy and other therapies synergistically.Herein,we developed doxorubicin-loaded gold nanovesicles(DGVs),offering infrared thermal(IRT) and photoacoustic(PA) dual-modal imaging guided mild hype rthermia-enhanced chemophotothermal cancer synergistic therapy.The DGVs are self-assembled by gold nanoparticles modified with amphiphilic copolymer in a predetermined concentration of doxorubicin through film rehydration method.Under the influence of laser excitation,the as-prepared DGVs exhibited good photothermal effect,which triggered the structural disruption of GVs and thus,allowed the efficient release of encapsulated DOX to enhance cell uptake for fluorescence imaging and tumor chemotherapy,respectively.In addition,DGVs also showed a strong PA and IRT signals in vivo.Our study demonstrated the potential of DGVs as stimuli-responsive drug delivery systems and cancer theranostics. | Zhuoting Deng Chao Jiang Muhammad Rizwan Younis Shan Lei Yaling He Haoxing Zheng Peng Huang Jing Lin | 2021 | Chinese Chemical Letters2021，32，8： | 0 |
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