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| 1 | 人食管和贲门癌前病变的细胞增生生物学指标研究显示文摘采用增生细胞核抗原(PCNA),Ki-67和溴脱氧尿啶嘧核苷(BudR)标记的S期细胞的三种生物学指标,测定人食管和贲门粘膜活检上皮正常和不同程度的癌前病变细胞增生状况。食管粘膜上皮从正常到基底细胞增生,上述指标变化幅度不大,但从基底细胞增生到间变时,PCNA和Ki-67阳性细胞数明显升高。贲门随上皮病变的加重,PCNA和Ki-67阳性细胞逐渐升高。在同一类病变,PCNA和Ki-67阳性细胞数几乎是BudR的2倍。结果提示三种指标均与食管和贲门上皮病变进展程度有关,能比较客观地评价其细胞增生动力学状况。PCNA可能是一种简便易行,特别适宜研究大范围人群细胞增生状况的生物学指标。 | 王立东 周琦 高珊珊 邢莹 李启驹 刘保池 裘宋良 Chung S.Yang | 1995 | 河南医科大学学报1995，30，2： | 7 |
| 2 | 食管和贲门癌前病变癌基因c-erbB_2、c-myc和cyclin D_1的表达研究显示文摘为了解食管和贲门癌变的分子生物学发生基础,采用免疫组化技术测定人食管和贲门正常上皮和癌前病变组织的癌基因蛋白c-erbB2,c-myc和cyclinD1的表达状况。研究对象来自食管癌高发区河南辉县。结果:在食管,未观察到c-erbB2的阳性表达(0/54);而c-myc和cyclinD1的阳性表达率分别为25%(6/24)和82%(94/115)。贲门上皮c-erbB2和c-myc的阳性表达率分别为73%(16/26)和78%(31/40),均明显高于食管组织的表达。贲门组织cyclinD1的阳性表达率为78%(31/40),但是,随着贲门上皮病变加重,cyclinD1的阳性表达率呈现下降趋势。提示同一地区食管和贲门癌前病变发生存在不同的分子学改变;食管和贲门癌变的不同阶段可能由多种癌基因参与作用;c-erbB2可能是贲门癌变的重要分子学变化。 | 王立东 周琦 李永欣 邢莹 刘保池 裘宋良 Susan Goldstein Stephenie T Shi Jun Y.Hong Chung S.Yang | 1995 | 河南医科大学学报1995，30，2： | 7 |
| 3 | The Soft X-ray Imager(SXI)on the SMILE Mission显示文摘The Soft X-ray Imager(SXI)is part of the scientific payload of the Solar wind Magnetosphere Ionosphere Link Explorer(SMILE)mission.SMILE is a joint science mission between the European Space Agency(ESA)and the Chinese Academy of Sciences(CAS)and is due for launch in 2025.SXI is a compact X-ray telescope with a wide field-of-view(FOV)capable of encompassing large portions of Earth’s magnetosphere from the vantage point of the SMILE orbit.SXI is sensitive to the soft X-rays produced by the Solar Wind Charge eXchange(SWCX)process produced when heavy ions of solar wind origin interact with neutral particles in Earth’s exosphere.SWCX provides a mechanism for boundary detection within the magnetosphere,such as the position of Earth’s magnetopause,because the solar wind heavy ions have a very low density in regions of closed magnetic field lines.The sensitivity of the SXI is such that it can potentially track movements of the magnetopause on timescales of a few minutes and the orbit of SMILE will enable such movements to be tracked for segments lasting many hours.SXI is led by the University of Leicester in the United Kingdom(UK)with collaborating organisations on hardware,software and science support within the UK,Europe,China and the United States. | S.Sembay A.L.Alme D.Agnolon T.Arnold A.Beardmore A.Belén Balado Margeli C.Bicknell C.Bouldin G.Branduardi-Raymont T.Crawford J.P.Breuer T.Buggey G.Butcher R.Canchal J.A.Carter A.Cheney Y.Collado-Vega H.Connor T.Crawford N.Eaton C.Feldman C.Forsyth T.Frantzen G.Galgóczi J.Garcia G.Y.Genov C.Gordillo H-P.Gröbelbauer M.Guedel Y.Guo M.Hailey D.Hall R.Hampson J.Hasiba O.Hetherington A.Holland S-Y.Hsieh M.W.J.Hubbard H.Jeszenszky M.Jones T.Kennedy K.Koch-Mehrin S.Kögl S.Krucker K.D.Kuntz C.Lakin G.Laky O.Lylund A.Martindale J.Miguel Mas Hesse R.Nakamura K.Oksavik N.Østgaard H.Ottacher R.Ottensamer C.Pagani S.Parsons P.Patel J.Pearson G.Peikert F.S.Porter T.Pouliantis B.H.Qureshi W.Raab G.Randal A.M.Read N.M.M.Roque M.E.Rostad C.Runciman S.Sachdev A.Samsonov M.Soman D.Sibeck S.Smit J.Søndergaard R.Speight S.Stavland M.Steller TianRan Sun J.Thornhill W.Thomas K.Ullaland B.Walsh D.Walton C.Wang S.Yang | 2024 | Earth and Planetary Physics2024，8，1： | 4 |
| 4 | Methods for a blind analysis of isobar data collected by the STAR collaboration显示文摘In 2018,the STAR collaboration collected data from^(96)_(44)Ru+^(96)_(44)Ru and^(96)_(40)Zr+^(96)_(40)Zr at√^(S)NN=200 Ge V to search for the presence of the chiral magnetic effect in collisions of nuclei.The isobar collision species alternated frequently between 9644 Ru+^(96)_(44)Ru and^(96)_(40)Zr+^(96)_(40)Zr.In order to conduct blind analyses of studies related to the chiral magnetic effect in these isobar data,STAR developed a three-step blind analysis procedure.Analysts are initially provided a'reference sample'of data,comprised of a mix of events from the two species,the order of which respects time-dependent changes in run conditions.After tuning analysis codes and performing time-dependent quality assurance on the reference sample,analysts are provided a species-blind sample suitable for calculating efficiencies and corrections for individual≈30-min data-taking runs.For this sample,species-specific information is disguised,but individual output files contain data from a single isobar species.Only run-by-run corrections and code alteration subsequent to these corrections are allowed at this stage.Following these modifications,the'frozen'code is passed over the fully un-blind data,completing the blind analysis.As a check of the feasibility of the blind analysis procedure,analysts completed a'mock data challenge,'analyzing data from Au+Au collisions at√^(S)NN=27 Ge V,collected in 2018.The Au+Au data were prepared in the same manner intended for the isobar blind data.The details of the blind analysis procedure and results from the mock data challenge are presented. | J.Adam L.Adamczyk J.R.Adams J.K.Adkins G.Agakishiev M.M.Aggarwal Z.Ahammed I.Alekseev D.M.Anderson A.Aparin E.C.Aschenauer M.U.Ashraf F.G.Atetalla A.Attri G.S.Averichev V.Bairathi K.Barish A.Behera R.Bellwied A.Bhasin J.Bielcik J.Bielcikova L.C.Bland I.G.Bordyuzhin J.D.Brandenburg A.V.Brandin J.Butterworth H.Caines M.Calderon de la Barca Sanchez D.Cebra I.Chakaberia P.Chaloupka B.K.Chan F-H.Chang Z.Chang N.Chankova-Bunzarova A.Chatterjee D.Chen J.Chen J.H.Chen X.Chen Z.Chen J.Cheng M.Cherney M.Chevalier S.Choudhury W.Christie X.Chu H.J.Crawford M.Csanad M.Daugherity T.G.Dedovich I.M.Deppner A.A.Derevschikov L.Didenko X.Dong J.L.Drachenberg J.C.Dunlop T.Edmonds N.Elsey J.Engelage G.Eppley S.Esumi O.Evdokimov A.Ewigleben O.Eyser R.Fatemi S.Fazio P.Federic J.Fedorisin C.J.Feng Y.Feng P.Filip E.Finch Y.Fisyak A.Francisco L.Fulek C.A.Gagliardi T.Galatyuk F.Geurts A.Gibson K.Gopal X.Gou D.Grosnick W.Guryn A.I.Hamad A.Hamed S.Harabasz J.W.Harris S.He W.He X.H.He Y.He S.Heppelmann S.Heppelmann N.Herrmann E.Hoffman L.Holub Y.Hong S.Horvat Y.Hu H.Z.Huang S.L.Huang T.Huang X.Huang T.J.Humanic P.Huo G.Igo D.Isenhower W.W.Jacobs C.Jena A.Jentsch Y.Ji J.Jia K.Jiang S.Jowzaee X.Ju E.G.Judd S.Kabana M.L.Kabir S.Kagamaster D.Kalinkin K.Kang D.Kapukchyan K.Kauder H.W.Ke D.Keane A.Kechechyan M.Kelsey Y.V.Khyzhniak D.P.Kikoła C.Kim B.Kimelman D.Kincses T.A.Kinghorn I.Kisel A.Kiselev M.Kocan L.Kochenda L.K.Kosarzewski L.Kramarik P.Kravtsov K.Krueger N.Kulathunga Mudiyanselage L.Kumar S.Kumar R.Kunnawalkam Elayavalli J.H.Kwasizur R.Lacey S.Lan J.M.Landgraf J.Lauret A.Lebedev R.Lednicky J.H.Lee Y.H.Leung C.Li C.Li W.Li W.Li X.Li Y.Li Y.Liang R.Licenik T.Lin Y.Lin M.A.Lisa F.Liu H.Liu P.Liu P.Liu T.Liu X.Liu Y.Liu Z.Liu T.Ljubicic W.J.Llope R.S.Longacre N.S.Lukow S.Luo X.Luo G.L.Ma L.Ma R.Ma Y.G.Ma N.Magdy R.Majka D.Mallick S.Margetis C.Markert H.S.Matis J.A.Mazer N.G.Minaev S.Mioduszewski B.Mohanty I.Mooney Z.Moravcova D.A.Morozov M.Nagy J.D.Nam Md.Nasim K.Nayak D.Neff J.M.Nelson D.B.Nemes M.Nie G.Nigmatkulov T.Niida L.V.Nogach T.Nonaka A.S.Nunes G.Odyniec A.Ogawa S.Oh V.A.Okorokov B.S.Page R.Pak A.Pandav Y.Panebratsev B.Pawlik D.Pawlowska H.Pei C.Perkins L.Pinsky R.L.Pinter J.Pluta J.Porter M.Posik N.K.Pruthi M.Przybycien J.Putschke H.Qiu A.Quintero S.K.Radhakrishnan S.Ramachandran R.L.Ray R.Reed H.G.Ritter O.V.Rogachevskiy J.L.Romero L.Ruan J.Rusnak N.R.Sahoo H.Sako S.Salur J.Sandweiss S.Sato W.B.Schmidke N.Schmitz B.R.Schweid F.Seck J.Seger M.Sergeeva R.Seto P.Seyboth N.Shah E.Shahaliev P.V.Shanmuganathan M.Shao A.I.Sheikh W.Q.Shen S.S.Shi Y.Shi Q.Y.Shou E.P.Sichtermann R.Sikora M.Simko J.Singh S.Singha N.Smirnov W.Solyst P.Sorensen H.M.Spinka B.Srivastava T.D.S.Stanislaus M.Stefaniak D.J.Stewart M.Strikhanov B.Stringfellow A.A.P.Suaide M.Sumbera B.Summa X.M.Sun X.Sun Y.Sun Y.Sun B.Surrow D.N.Svirida P.Szymanski A.H.Tang Z.Tang A.Taranenko T.Tarnowsky J.H.Thomas A.R.Timmins D.Tlusty M.Tokarev C.A.Tomkiel S.Trentalange R.E.Tribble P.Tribedy S.K.Tripathy O.D.Tsai Z.Tu T.Ullrich D.G.Underwood I.Upsal G.Van Buren J.Vanek A.N.Vasiliev I.Vassiliev F.Videbæk S.Vokal S.A.Voloshin F.Wang G.Wang J.S.Wang P.Wang Y.Wang Y.Wang Z.Wang J.C.Webb P.C.Weidenkaff L.Wen G.D.Westfall H.Wieman S.W.Wissink R.Witt Y.Wu Z.G.Xiao G.Xie W.Xie H.Xu N.Xu Q.H.Xu Y.F.Xu Y.Xu Z.Xu Z.Xu C.Yang Q.Yang S.Yang Y.Yang Z.Yang Z.Ye Z.Ye L.Yi K.Yip Y.Yu H.Zbroszczyk W.Zha C.Zhang D.Zhang S.Zhang S.Zhang X.P.Zhang Y.Zhang Y.Zhang Z.J.Zhang Z.Zhang Z.Zhang J.Zhao C.Zhong C.Zhou X.Zhu Z.Zhu M.Zurek M.Zyzak STAR Collaboration Abilene | 2021 | Nuclear Science and Techniques2021，32，5： | 3 |
| 5 | In vivo neuronal and astrocytic activation in somatosensory cortex by acupuncture stimuli显示文摘Acupuncture is a medical treatment that has been widely pra cticed in China for over 3000 years,yet the neural mechanisms of acupuncture are not fully understood.We hypothesized that neurons and astrocytes act independently and synergistically under acupuncture stimulation.To investigate this,we used two-photon in vivo calcium reco rding to observe the effects of acupuncture stimulation at ST36(Zusanli)in mice.Acupuncture stimulation in peripheral acupoints potentiated calcium signals of pyramidal neurons and astrocytes in the somatosensory cortex and resulted in late-onset calcium transients in astrocytes.Chemogenetic inhibition of neurons augmented the astrocytic activity.These findings suggest that acupuncture activates neuronal and astrocytic activity in the somatosensory co rtex and provide evidence for the involvement of both neurons and astrocytes in acupuncture treatment. | Xiao-Yue Chang Kai Chen Tong Cheng Pui To Lai Li Zhang Kwok-Fai So Edward S.Yang | 2022 | Neural Regeneration Research2022，17，11： | 2 |
| 6 | 人贲门癌WAF-1基因和P53肿瘤抑制基因表达的初步研究显示文摘采用免疫组织化学方法,初步观察34例手术切除后的贲门癌组织WAF-1基因蛋白(P21)的表达状况并与P53肿瘤抑制基因蛋白的免疫组化结果进行比较。贲门癌组织P21免疫组化阳性率为74%;癌细胞P21免疫反应强度与正常细胞相似。 | 王立东 周琦 高珊珊 杨光育 Chung S.Yang | 1995 | 河南医科大学学报1995，30，2： | 2 |
| 7 | 人食管和贲门癌前病变和癌组织P40上皮特异性蛋白表达的研究显示文摘利用鼠单克隆抗体7E(12)H(12),对人食管和贲门正常粘膜上皮,癌前病变和癌组织的P40上皮特异性蛋白表达进行比较研究。结果表明,食管和贲门上皮P40蛋白的表达和分布明显不同。贲门柱状上皮P40蛋白的免疫反应强度和发生率明显高于鳞状上皮(相差8倍)。食管固有腺上皮细胞也出现较强的P40蛋白免疫反应性。在贲门组织中,P40蛋白免疫反应62%发生在细胞浆;21%发生在细胞核;17%同时发生在胞浆和胞核。而在食管,其反应全部在胞浆。随着病变的加重,食管和贲门P40蛋白的表达均出现增高的趋势。 | 王立东 周琦 陈玉龙 周芸 刘保池 裘宋良 Theresa Smith Koron M.Das Chung S.Yang | 1995 | 河南医科大学学报1995，30，2： | 2 |
| 8 | Measurement of away-side broadening with self-subtraction of flow in Au+Au collisions at √sNN=200 GeV显示文摘High transverse momentum(pT)particle production is suppressed owing to the parton(jet)energy loss in the hot dense medium created in relativistic heavy-ion collisions.Redistribution of energy at low-to-modest pT has been difficult to measure,owing to large anisotropic backgrounds.We report a data-driven method for background evaluation and subtraction,exploiting the away-side pseudorapidity gaps,to measure the jetlike correlation shape in Au+Au collisions at √sNN=200 GeV in the STAR experiment.The correlation shapes,for trigger particles pT>3GeV/c and various associated particle pT ranges within 0.5 | L.Adamczyk J.R.Adams J.K.Adkins G.Agakishiev M.M.Aggarwal Z.Ahammed I.Alekseev D.M.Anderson A.Aparin E.C.Aschenauer M.U.Ashraf F.G.Atetalla A.Attri G.S.Averichev V.Bairathi K.Barish A.Behera R.Bellwied A.Bhasin J.Bielcik J.Bielcikova L.C.Bland I.G.Bordyuzhin J.D.Brandenburg A.V.Brandin J.Butterworth H.Caines M.Calderón de la Barca Sánchez D.Cebra I.Chakaberia P.Chaloupka B.K.Chan F-H.Chang Z.Chang N.Chankova-Bunzarova A.Chatterjee D.Chen J.H.Chen X.Chen Z.Chen J.Cheng M.Cherney M.Chevalier S.Choudhury W.Christie X.Chu H.J.Crawford M.Csanád M.Daugherity T.G.Dedovich I.M.Deppner A.A.Derevschikov L.Didenko X.Dong J.L.Drachenberg J.C.Dunlop T.Edmonds N.Elsey J.Engelage G.Eppley S.Esumi O.Evdokimov A.Ewigleben O.Eyser R.Fatemi S.Fazio P.Federic J.Fedorisin C.J.Feng Y.Feng P.Filip E.Finch Y.Fisyak A.Francisco L.Fulek C.A.Gagliardi T.Galatyuk F.Geurts A.Gibson K.Gopal D.Grosnick W.Guryn A.I.Hamad A.Hamed S.Harabasz J.W.Harris S.He W.He X.H.He S.Heppelmann S.Heppelmann N.Herrmann E.Hoffman L.Holub Y.Hong S.Horvat Y.Hu H.Z.Huang S.L.Huang T.Huang X.Huang T.J.Humanic P.Huo G.Igo D.Isenhower W.W.Jacobs C.Jena A.Jentsch Y.JI J.Jia K.Jiang S.Jowzaee X.Ju E.G.Judd S.Kabana M.L.Kabir S.Kagamaster D.Kalinkin K.Kang D.Kapukchyan K.Kauder H.W.Ke D.Keane A.Kechechyan M.Kelsey Y.V.Khyzhniak D.P.Kikoła C.Kim B.Kimelman D.Kincses T.A.Kinghorn I.Kisel A.Kiselev M.Kocan L.Kochenda L.K.Kosarzewski L.Kramarik P.Kravtsov K.Krueger N.Kulathunga Mudiyanselage L.Kumar S.Kumar R.Kunnawalkam Elayavalli J.H.Kwasizur R.Lacey S.Lan J.M.Landgraf J.Lauret A.Lebedev R.Lednicky J.H.Lee Y.H.Leung C.Li W.Li W.Li X.Li Y.Li Y.Liang R.Licenik T.Lin Y.Lin M.A.Lisa F.Liu H.Liu P.Liu P.Liu T.Liu X.Liu Y.Liu Z.Liu T.Ljubicic W.J.Llope R.S.Longacre N.S.Lukow S.Luo X.Luo G.L.Ma L.Ma R.Ma Y.G.Ma N.Magdy R.Majka D.Mallick S.Margetis C.Markert H.S.Matis J.A.Mazer N.G.Minaev S.Mioduszewski B.Mohanty I.Mooney Z.Moravcova D.A.Morozov M.Nagy J.D.Nam Nasim Md K.Nayak D.Neff J.M.Nelson D.B.Nemes M.Nie G.Nigmatkulov T.Niida L.V.Nogach T.Nonaka A.S.Nunes G.Odyniec A.Ogawa S.Oh V.A.Okorokov B.S.Page R.Pak A.Pandav Y.Panebratsev B.Pawlik D.Pawlowska H.Pei C.Perkins L.Pinsky R.L.Pintér J.Pluta J.Porter M.Posik N.K.Pruthi M.Przybycien J.Putschke H.Qiu A.Quintero S.K.Radhakrishnan S.Ramachandran R.L.Ray R.Reed H.G.Ritter O.V.Rogachevskiy J.L.Romero L.Ruan J.Rusnak N.R.Sahoo H.Sako S.Salur J.Sandweiss S.Sato W.B.Schmidke N.Schmitz B.R.Schweid F.Seck J.Seger M.Sergeeva R.Seto P.Seyboth N.Shah E.Shahaliev P.V.Shanmuganathan M.Shao A.I.Sheikh F.Shen W.Q.Shen S.S.Shi Q.Y.Shou E.P.Sichtermann R.Sikora M.Simko J.Singh S.Singha N.Smirnov W.Solyst P.Sorensen H.M.Spinka B.Srivastava T.D.S.Stanislaus M.Stefaniak D.J.Stewart M.Strikhanov B.Stringfellow A.A.P.Suaide M.Sumbera B.Summa X.M.Sun X.Sun Y.Sun Y.Sun B.Surrow D.N.Svirida P.Szymanski A.H.Tang Z.Tang A.Taranenko T.Tarnowsky J.H.Thomas A.R.Timmins D.Tlusty M.Tokarev C.A.Tomkiel S.Trentalange R.E.Tribble P.Tribedy S.K.Tripathy O.D.Tsai Z.Tu T.Ullrich D.G.Underwood I.Upsal G.Van Buren J.Vanek A.N.Vasiliev I.Vassiliev F.Videbæk S.Vokal S.A.Voloshin F.Wang G.Wang J.S.Wang P.Wang Y.Wang Y.Wang Z.Wang J.C.Webb P.C.Weidenkaff L.Wen G.D.Westfall H.Wieman S.W.Wissink R.Witt Y.Wu Z.G.Xiao G.Xie W.Xie H.Xu N.Xu Q.H.Xu Y.F.Xu Y.Xu Z.Xu Z.Xu C.Yang Q.Yang S.Yang Y.Yang Z.Yang Z.Ye Z.Ye L.Yi K.Yip H.Zbroszczyk W.Zha C.Zhang D.Zhang S.Zhang S.Zhang X.P.Zhang Y.Zhang Y.Zhang Z.J.Zhang Z.Zhang Z.Zhang J.Zhao C.Zhong C.Zhou X.Zhu Z.Zhu M.Zurek M.Zyzak | 2020 | Chinese Physics C2020，44，10： | 2 |
| 9 | Molecular targets for the cancer preventive activity of tea polyphenols显示文摘 | Chung S.Yang Joshua D.Lambert ZheHou JihyeungJu GangLu XinpeiHao | 2006 | Mol Carcinog2006，，6： | 1 |
| 10 | Dynamic Scoring:Alternative Financing Schemes显示文摘 | Leeper E S.Yang | | 0，，： | 1 |
| 11 | Alleviating effects and mechanisms of action of large-leaf yellow tea drinking on diabetes and diabetic nephropathy in mice显示文摘Our previous study found that large-leaf yellow tea(LYT)had interesting hypoglycemic activity in high-fat diet-induced obese mice and highly safety in healthy mice. To study the anti-diabetic potential of LYT, the present study further investigated the preventive effects and mechanisms of action of LYT administration on diabetes and diabetic nephropathy in high-fat diet plus streptozotocin-induced diabetic mice. Results showed that LYT infusions(1/100 and 1/50, m/V)as drinking fluid for 4 weeks reduced diabetic polydipsia and polyuria, enhanced glucose tolerance and insulin sensitivity, and lowered fasting blood glucose level. The underlying mechanisms involve downregulation of gluconeogenesis(lower protein levels of TXNIP and FBP and enzyme activity of FBP), upregulation of lipid catabolism(higher protein levels of CPT-1α and PPARα), downregulation of lipogenesis(lower protein level of SREBP-1), and modification of the structure and abundance of gut microbiota to modulate metabolic homeostasis. Moreover, LYT administration prevented diabetic nephropathy, possibly due to reduced glucose-caused osmotic diuresis and lowered levels of renal PKC-β2, NLRP3 as well as membrane PKC-α, AQP2 and glycosylated AQP2 proteins. Taken together, LYT exhibits the activities in alleviating diabetic symptoms, ameliorating glucose and lipid dysmetabolism and fatty liver, and preventing diabetic nephropathy in diabetic mice. These activities may be explored for the prevention and treatment of diabetes in humans. | Guangshan Zhao Jianyuan Teng Ruixia Dong Qiuyan Ban Lian Yang Kang Du Yifei Wang Hanlin Pu Chung S.Yang Zhe Ren | 2023 | Food Science and Human Wellness2023，12，5： | 1 |
| 12 | Targeting DNA repair pathways to overcome cancer drug resistance显示文摘DNA damage response and DNA repair pathways are evolutionarily conserved from prokaryotes to eukaryotes to protect the host from genomic instability.Dysregulation of proteins involved in these pathways in mammalian cells increases genomic alterations leading to genomic instability,a well-established hallmark of cancer^([1,2]).However,our understanding of the signaling pathways to repair DNA damage in cancers has grown exponentially over the last decades. | Robert C.A.M.van Waardenburg Eddy S.Yang | 2021 | Cancer Drug Resistance2021，4，4： | 1 |
| 13 | An Optimal Product Mix for Hedging Longevity Risk in Life Insurance Companies: The Immunization Theory Approach显示文摘 | Jennifer L.Wang H.C.Huang Sharon S.Yang Jeffrey T.Tsai | 2010 | Journal of Risk and Insurance2010，，2： | 1 |
| 14 | High‐dose glucose‐insulin‐potassium treatment reduces myocardial apoptosis in patients with acute myocardial infarction显示文摘 | L.Zhang L.Zhang Y. H.Li H. Y.Zhang M. L.Chen M.‐M.Gao A. H.Hu H. S.Yang H. S.Yang | 2005 | European Journal of Clinical Investigation2005，，3： | 1 |
| 15 | Sideband suppression in time-modulated linear arrays by the differential evolution algorithm显示文摘 | S.Yang Y.B.Gan A.Qing | | 0，，01： | 1 |
| 16 | Corrigendum to 'Dark tea: A popular beverage with possible medicinal application' [Chinese Herbal Medicines 15 (2023) 33-36]显示文摘When this paper was first published,the authors'name Miamoiao Lea was incomplete.The corrected author name has been shown above.The authors would like to apologise for any inconvenience caused. | Hongjing Pan Miaomiao Le Chunnian He Chung S.Yang Tiejun Ling | 2023 | Chinese Herbal Medicines2023，15，4： | 0 |
| 17 | The technology for detection of gamma-ray burst with GECAM satellite显示文摘Introduction The main physical objective of the GECAM satellite is to detect gamma-ray bursts,which is related to gravitational waves of double compact object mergers.The GECAM satellite also detects and investigates various bursts of high-energy celestial bodies.Purposes and methods In this study,we designed,developed and calibrated the payload and launched it into orbit with GECAM satellite.The payload consists of the gamma ray detector(GRD,for detecting 4 keV–4 MeV X/γray),the charged particle detector(CPD,for detecting 150 keV–5 MeV charged particle),and the electronic box(EBOX).The all-sky field coverage is achieved via two 229-degree large-area satellites positioned 180 degrees apart and are on opposite sides of the geo-center.Each satellite is equipped with 25 GRDs and 8 CPDs;thus,the satellite can identify charged particle bursts in space.Gamma-ray detectors adopt lanthanum bromide crystal technology combined with silicon photomultipliers.This is the first time that this technology was used massively in space detectors.Conclusions The GECAM satellite can quickly determine the direction of gamma-ray bursts(positioning)via indexing and fitting method,while the transmit variability,energy spectrum and direction of the gamma-ray bursts guide subsequent observations through the Beidou-3 RDSS in quasi-real time.It will play an important role in the study of high energy celestial bursts. | X.Q.Li X.Y.Wen Z.H.An C.Cai Z.Chang G.Chen C.Chen Y.Y.Du M.Gao R.Gao K.Gong D.Y.Guo J.J.He D.J.Hou Y.G.Li C.Y.Li G.Li L.Li X.F.Li M.S.Li X.H.Liang X.J.Liu Y.Q.Liu F.J.Lu H.Lu B.Meng W.X.Peng F.Shi X.L.Sun H.Wang J.Z.Wang Y.S.Wang H.Z.Wang X.Wen S.Xiao S.L.Xiong Y.B.Xu Y.P.Xu S.Yang J.W.Yang Q.B.Yi D.L.Zhang Fan Zhang S.N.Zhang C.Y.Zhang C.M.Zhang Fei Zhang X.Y.Zhao Y.Zhao X.Zhou C.S.Zhang J.P.Yu L.Chang K.K.Zhang J.Huang Y.M.Chen X.B.Han | 2022 | Radiation Detection Technology and Methods2022，6，1： | 0 |
| 18 | Quality assurance test and failure analysis of SiPM arrays of GECAM satellites显示文摘Background The Gravitational wave high-energy Electromagnetic Counterpart All-sky Monitor(GECAM)satellite developed a SiPM-based gamma-ray detector to monitor the gravitational wave-related GRBs and guide subsequent observations in other wavelengths of EM.Purpose As all the available SiPM devices belong to commercial grade,quality assurance tests need to be performed in accordance with the aerospace specifcations.Methods In the SiPM application of GECAM,quality assurance experiments were conducted.The mechanism of the failure of SiPM devices was analyzed during the development process.Result Based on the quality assurance test results,the fnal pass rate of SiPM array was 95%.Based on the failure analysis,it was found that a piece of SiPM had a leakage channel after longtime operation due to device defects.Conclusion According to the accumulated experience,in the reliability test of SiPM,it is necessary to pay special attention to test the impedance of each pin of SiPM to ground and confrm that the power switch state of SiPM is controllable. | D.L.Zhang M.Gao X.L.Sun X.Q.Li Z.H.An X.Y.Wen C.Cai Z.Chang G.Chen C.Chen Y.Y.Du R.Gao K.Gong D.Y.Guo J.J.He D.J.Hou Y.G.Li C.Y.Li G.Li L.Li X.F.Li M.S.Li X.H.Liang X.J.Liu Y.Q.Liu F.J.Lu H.Lu B.Meng W.X.Peng F.Shi H.Wang J.Z.Wang Y.S.Wang H.Z.Wang X.Wen S.Xiao S.L.Xiong Y.B.Xu Y.P.Xu S.Yang J.W.Yang Fan.Zhang S.N.Zhang C.Y.Zhang C.M.Zhang Fei Zhang X.Y.Zhao X.Zhou | 2022 | Radiation Detection Technology and Methods2022，6，1： | 0 |
| 19 | The design and performance of GRD onboard the GECAM satellite显示文摘Background Each GECAM satellite payload contains 25 gamma-ray detectors(GRDs),which can detect gamma-rays and particles and can roughly localize the Gamma-Ray Bursts(GRBs).GRD was designed using lanthanum bromide(LaBr3)crystal as the sensitive material with the rear end coupled with silicon photomultiplier(SiPM)array for readout.Purpose In aerospace engineering design of GRD,there are many key points to be studied.In this paper,we present the specific design scheme of GRD,the assembly and the performance test results of detectors.Methods Based on Monte Carlo simulation and experimental test results,the specific schematic design and assembling process of GRD were optimized.After being fully assembled,the GRDs were conducted performance tests by using radioactive source and also conducted random vibration tests.Result and conclusion The test results show that all satellite-borne GRDs have energy resolution<16%at 59.5 keV,meeting requirements of satellite in scientific performance.The random vibration test shows that GRD can maintain in a stable performance,which meets the requirement of spatial application. | Z.H.An X.L.Sun D.L.Zhang S.Yang X.Q.Li X.Y.Wen K.Gong X.H.Liang X.J.Liu Y.Q.Liu Y.G.Li S.L.Xiong Y.B.Xu Fan Zhang X.Y.Zhao C.Cai Z.Chang G.Chen C.Chen Y.Y.Du P.Y.Feng M.Gao R.Gao D.Y.Guo J.J.He D.J.Hou C.Y.Li G.Li L.Li X.F.Li M.S.Li F.J.Lu H.Lu B.Meng W.X.Peng F.Shi H.Wang J.Z.Wang Y.S.Wang H.Z.Wang X.Wen S.Xiao Y.P.Xu J.W.Yang Q.B.Yi S.N.Zhang C.Y.Zhang C.M.Zhang Fei Zhang Y.Zhao X.Zhou | 2022 | Radiation Detection Technology and Methods2022，6，1： | 0 |
| 20 | The design and performance of charged particle detector onboard the GECAM mission显示文摘Background The Gravitational wave highly energetic Electromagnetic Counterpart All-sky Monitor(GECAM)is dedicated to detecting gravitational wave gamma-ray bursts.It is capable of all-sky monitoring over and discovering gamma-ray bursts and new radiation phenomena.GECAM consists of two microsatellites,each equipped with 8 charged particle detectors(CPDs)and 25 gamma-ray detectors(GRDs).Purpose The CPD is used to measure charged particles in the space environment,monitor energy and flow intensity changes,and identify between gamma-ray bursts and space charged particle events in conjunction with GRD.Methods CPD uses plastic scintillator as the sensitive material for detection,silicon photomultiplier array as the optically readable device,and the inlaid Am-241 radioactive source as the onboard calibration means.Conclusion In this paper,we will present the working principle,physical design,functional implementation and preliminary performance test results of the CPD.As a result,the energy range of electron,gamma-ray detection efficiency and dead time are tested to be better than the indexes required through the ground calibration experiment. | Y.B.Xu X.Q.Li X.L.Sun S.Yang H.Wang W.X.Peng X.H.Liang K.Gong Y.Q.Liu D.Y.Guo X.Y.Zhao C.Y.Li Z.H.An J.J.He X.J.Liu X.Y.Wen S.L.Xiong Fan Zhang D.L.Zhang C.Y.Zhang C.Cai Z.Chang G.Chen C.Chen Y.Y.Du M.Gao R.Gao D.J.Hou Y.G.Li G.Li L.Li X.F.Li M.S.Li F.J.Lu H.Lu B.Meng F.Shi J.Z.Wang Y.S.Wang H.Z.Wang X.Wen S.Xiao Y.P.Xu J.W.Yang Q.B.Yi S.N.Zhang C.M.Zhang F.Zhang Y.Zhao X.Zhou | 2022 | Radiation Detection Technology and Methods2022，6，1： | 0 |
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