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| 1 | The Role of TNF Related Apoptosis-Inducing Ligand in Neurodegenerative Diseases显示文摘A hallmark of all forms of neurodegenerative diseases is impairment of neuronal functions, and in many cases neuronal cell death. Although the etiology of neurodegenerative diseases may be distinct, different diseases display a similar pathogenesis, for example abnormal immunity within the central nervous system (CNS), activation of macrophage/microglia and the involvement of proinflammatory cytokines. Recent studies show that neurons in a neurodegenerative state undergo a highly regulated programmed cell death, also called apoptosis. TNF-related apoptosis-inducing ligand (TRAIL), a member of the TNF family, has been shown to be involved in apoptosis during many diseases. As one member of a death ligand family, TRAIL was originally thought to target only tumor cells and was not present in CNS. However, recent data showed that TRAIL was unregulated in HIV-1-infected and immune-activated macrophages, a major disease inducing cell during HIV-1-associated dementia (HAD). TRAIL is also induced on neuron by β-amyloid protein, an important pathogen for Alzheimer's disease. In this review, we summarize the possible common aspects that TRAIL involved those neurodegenerative diseases, TRAIL induced apoptosis signaling in the CNS cells, and specific role of TRAIL in individual diseases. Cellular & Molecular Immunology. 2005;2(2):113-122. | Y.Huang N.Erdmann H.Peng Y.Zhao | 2005 | Cellular & Molecular Immunology2005,2,2: | 15 |
| 2 | Detection and widespread distribution of sodium channel alleles characteristic of insecticide resistance in Culex pipiens complex mosquitoes in China显示文摘 | Z.‐M.WANG C.‐X.LI D.XING Y.‐H.YU N.LIU R.‐D.XUE Y.‐D.DONG T.‐Y.ZHAO | 2012 | Medical and Veterinary Entomology2012,,2: | 2 |
| 3 | DEVELOPMENT AND APPLICATION OF ADAPTIVE MESH TECHNIQUE IN THREE DIMENSIONAL NUMERICAL SIMULATION OF WELDING PROCESS显示文摘The adaptive mesh mesh technique is developed and applied in three dimensional numerical simulation of welding process on the base of the commercial software. Special user subroutine is worked out to accom- plish this function.This technique can make the dense mesh moving simultaneously with the heat source while the other area of the structure with much coarser mesh, greatly reducing the number of nodes and elements in the analysis.Temperature field,displacement and stress distributions during welding pro- cess me analyzed by FEM method with adaptive mesh and the analysis is also conducted with normal FEM method. The temperature field,displacement and stress distributions obtained with both methods are shown in contrast. The results show that the temperature fields and the displacement distributions of simulation on adaptive mesh correspond wery well with that of without adaptive mesh. Though the stress distributions have some difference,but the trends of the stress distribution are corresponding.The com- parison of the computing time of the two meshes indicates that the adaptive that the adaptive mesh can greatly reduce the calculation time when used for welding process. | Q. Y.Shi A. L. Lu H. Y.Zhao A.P. Wu (Department of Mechanical Engineering, Tsinghua University, Beijing 100084, China) | 2000 | Acta Metallurgica Sinica(English Letters)2000,13,1: | 2 |
| 4 | Rapid Detection of BF Haplotypes by a Semi‐nested Polymerase Chain Reaction, which Causes Resistance/Susceptibility to Marek’s Disease in Chicken显示文摘 | Y.‐C.Jin P.Wei X.‐X.Wei Z.‐Y.Zhao Y.Li | 2010 | Scandinavian Journal of Immunology2010,,2: | 2 |
| 5 | Combined approach for analysing evolutionary power spectra of a track-soil system under moving random loads显示文摘The pseudo-excitation method combined with the integral transform method (PEM-ITM) is presented to investigate the ground vibration of a coupled track-soil system induced by moving random loads. Commonly in the track model, the rail, sleepers, rail pads, and ballast are modelled as an infinite Euler beam, discretely distributed masses, discretely distributed vertical springs, and a viscoelastic layer, respectively. The soil is regarded as a homogenous isotropic half-space coupled with the track using the boundary condition at the surface of the ground. By introducing a pseudo-excitation, the random vibration analysis of the coupled system is converted into a harmonic analysis. The analytical form of evolutionary power spectral density responses of the simplified coupled track-soil system under a random moving load is derived in the frequency/wavenumber domain by PEM-ITM. In the numerical examples, the effects of different parameters, such as the moving speed, the soil properties, and the coherence of moving loads, on the ground response are investigated. | Y.Zhao L.T.Si H.Ouyang | 2019 | Acta Mechanica Sinica2019,35,3: | 2 |
| 6 | Rapid Detection of BF Haplotypes by a Semi‐nested Polymerase Chain Reaction, which Causes Resistance/Susceptibility to Marek’s Disease in Chicken显示文摘 | Y.‐C.Jin P.Wei X.‐X.Wei Z.‐Y.Zhao Y.Li | 2010 | Scandinavian Journal of Immunology2010,,2: | 2 |
| 7 | Multilineage differentiation of dental follicle cells and the roles of Runx2 over‐expression in enhancing osteoblast/cementoblast‐related gene expression in dental follicle cells显示文摘 | K.Pan Q.Sun J.Zhang S.Ge S.Li Y.Zhao P.Yang | 2010 | Cell Proliferation2010,,3: | 1 |
| 8 | Antimicrobial Chitosan‐Lysozyme (CL) Films and Coatings for Enhancing Microbial Safety of Mozzarella Cheese显示文摘 | J.Duan S.‐I.Park M.A.Daeschel Y.Zhao | 2007 | Journal of Food Science2007,,9: | 1 |
| 9 | Symbol error rate of selection amplify-and-forward relay systems显示文摘 | Y.ZHAO R.ADVE T.J.LIM | | 0,,11: | 1 |
| 10 | Dyspepsia and irritable bowel syndrome in China: a population‐based endoscopy study of prevalence and impact显示文摘 | Y.Zhao D.Zou R.Wang X.Ma X.Yan X.Man L.Gao J.Fang H.Yan X.Kang P.Yin Y.Hao Q.Li J.Dent J.Sung K.Halling B.Wernersson S.Johansson J.He | 2010 | Alimentary Pharmacology & Therapeutics2010,,4: | 1 |
| 11 | Us Knows Us in the UK:On Director Networks and CEO Compensation显示文摘 | Renneboog L Y.Zhao | | 0,,: | 1 |
| 12 | Multilineage differentiation of dental follicle cells and the roles of Runx2 over‐expression in enhancing osteoblast/cementoblast‐related gene expression in dental follicle cells显示文摘 | K.Pan Q.Sun J.Zhang S.Ge S.Li Y.Zhao P.Yang | 2010 | Cell Proliferation2010,,3: | 1 |
| 13 | Symbol error rate of selection amplify-and-forward relay systems显示文摘 | Y.ZHAO R.ADVE T.J.LIM | | 0,,11: | 1 |
| 14 | 查看详情显示文摘 | W.Li Y.Zhao | | 0,,: | 1 |
| 15 | 查看详情显示文摘 | Y.Shirai Y.Zhao L.Cheng J.M.Tour | | 0,,: | 1 |
| 16 | New polypropylene blends toughened by polypropylene/poly(ethylene-co-propylene) in-reactor alloy: Compositional and morphological influence on mechanical properties显示文摘 | R.B.Li X.Q.Zhang Y.Zhao | | 0,,21: | 1 |
| 17 | Improvement of A21978C production in Streptomyces roseosporus by reporter‐guided rpsL mutation selection显示文摘 | L.Wang Y.Zhao Q.Liu Y.Huang C.Hu G.Liao | 2012 | Journal of Applied Microbiology2012,,6: | 1 |
| 18 | Hesperomyces virescens(Fungi, Ascomycota, Laboulbeniales)attacking Harmonia axyridis(Coleoptera, Coccinellidae)in its native range显示文摘This study intended to find data on obligate ectoparasitic Laboulbeniales(Fungi,Ascomycota)on Chinese Harmonia axyridis(Coleoptera,Coccinellidae).After having screened over four thousand dried specimens of H.axyridis and close relatives,we present the first(historical)record of Chinese H.axyridis infected with Hesperomyces virescens.We suggest that H.virescens is a historically globally distributed species and hypothesize that(native)infection was lost when H.axyridis was introduced in North America. | Haelewaters Danny Richard F.Comont Serena Y.Zhao Donald H.Pfister | 2014 | Chinese Science Bulletin2014,59,5: | 1 |
| 19 | Pioglitazone induces regression and stabilization of coronary atherosclerotic plaques in patients with impaired glucose tolerance显示文摘 | H.‐B.Yang X.‐Y.Zhao J.‐Y.Zhang Y.‐Y.Du X.‐F.Wang | 2012 | Diabetic Medicine2012,,3: | 1 |
| 20 | 多输出隔离电源利用次级侧同步后置稳压器实现高效率显示文摘 | Charlie Y.Zhao Wei Chen Chiawei Liao 翠钦 | 2003 | 电子设计应用2003,,3: | 0 |