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| 1 | Correlation between lower gastrointestinal tract symptoms and quality of life in patients with stable chronic obstructive pulmonary disease显示文摘OBJECTIVE:To explore correlations between the symptoms of constipation and abdominal distention and severity of chronic obstructive pulmonary disease(COPD)in patients with stable disease.METHODS:We studied 191 patients with stable COPD(according to defined criteria)in this cross-sectional study from four three-level class A Chinese medicine hospitals in China.We built an Epidata 3.0 database and performed statistical analysis with SPSS,version 17.0.We analyzed correlations between the frequency of lower gastrointestinal tract symptoms(constipation and abdominal distention)and scores for major pulmonary symptoms(cough,sputum and wheezing)based on the St.George's Respiratory Questionnaire(SGRQ),6-minute walking distance(6MWD)and frequency of acute exacerbations of COPD(AECOPD).RESULTS:In addition to their pulmonary symptoms,39.79%and 40.31%of study patients withstable COPD reported constipation and abdominal distention,respectively.Scores for major pulmonary symptoms(cough,sputum and wheezing),AECOPD and SGRQ values in patients with constipation and abdominal distention were significantly greater,and the 6MWD markedly shorter,than in those without them.According to Pearson's correlation analysis,there were strong correlations between these lower gastrointestinal tract symptoms and scores for pulmonary symptoms,SGRQ,6MWD and AECOPD.CONCLUSION:Lower gastrointestinal tract symptoms such as constipation and abdominal distention can adversely affect pulmonary symptoms,frequency of acute exacerbations and quality of life in patients with stable COPD. | Yan Sun Fengjie Zheng Yuhang Li Ruohan Wu Yuchao Liu Miao Liu Jinchao Zhang Kuo Gao | 2013 | Journal of Traditional Chinese Medicine2013，33，5： | 10 |
| 2 | In situ sulfur-doped graphene nanofiber network as efficient metal-free electrocatalyst for polysulfides redox reactions in lithium–sulfur batteries显示文摘The major challenge for realistic application of Li-S batteries lies in the great difficulty in breaking through the obstacles of the sluggish kinetics and polysulfides shuttle of the sulfur cathode at high sulfur loading for continuously high sulfur utilization during prolonged charge-discharge cycles.Here we demonstrate that large percentage of sulfur can be effectively incorporated within a three-dimensional(3D)nanofiber network of high quality graphene from chemical vapor deposition(CVD),through a simple ball-milling process.While high quality graphene network provided continuous and durable channels to enable efficient transport of lithium ions and electrons,the in-situ sulfur doping from the alloying effect of ball milling facilitated desirable affinity with entire sulfur species to prevent sulfur loss and highly active sites to propel sulfur redox reactions over cycling.This resulted in remarkable rate-performance and excellent cycling stability,together with large areal capacity at very high sulfur mass loading(Specific capacity over 666 mAh g-1after 300 cycles at 0.5 C,and areal capacity above 5.2 mAh cm-2at 0.2C at sulfur loading of 8.0 mg cm-2 and electrolyte/sulfur(E/S)ratio of 8μL mg-1;and high reversible areal capacities of 13.1 m Ah cm-2 at a sulfur load of 15 mg cm-2 and E/S of 5μL mg-1). | Shijie Zhang Peng Zhang Ruohan Hou Bin Li Yongshang Zhang Kangli Liu Xilai Zhang Guosheng Shao | 2020 | Journal of Energy Chemistry2020，29，8： | 4 |
| 3 | Confining sulfur in intact freestanding scaffold of yolk-shell nanofibers with high sulfur content for lithium-sulfur batteries显示文摘Nanostructure design holds great potential in fabricating sulfur electrodes that host a high sulfur loading and still attain high electrochemical utilization for the developing of high-energy-density lithium-sulfur(Li-S) batteries. In this contribution, we introduce the yolk-shell structure into a freestanding carbon nanofibers film and construct a complete hollow yolk-shell Ti O2/carbon nanofibers@void@TiN@carbon(TiO2-CNFs@void@Ti N@C) composite. With inherent double conductive network and strong adsorption capability for polysulfides, the Ti O2-CNFs@void@Ti N@C composite can not only provide sufficient electrical contact for the insulating sulfur, but also effectively entrap polysulfides for prolonged cycle life. As a result, an excellent capacity retention ratio of 60.9% after 1000 cycles at 1 C as well as a high capacity of688.5 mA h g^(-1) at 5 C rate is accomplished with the cells employing Ti O2-CNFs@void@TiN @C as a cathode substrate for sulfur. Moreover, the TiO2-CNFs@void@Ti N@C composite, with a high S mass loading of9.5 mg cm^(-2), delivers a superb areal capacity of 8.2 mAh cm^(-2). | Xilai Zhang Peng Zhang Shijie Zhang Yongshang Zhang Ruohan Hou Kangli Liu Fujun Miao Guosheng Shao | 2020 | Journal of Energy Chemistry2020，29，12： | 2 |
| 4 | Sugarcane bagasse dietary fiber as an adjuvant therapy for stable chronic obstructive pulmonary disease:a four-center,randomized,double-blind,placebo-controlled study显示文摘OBJECTIVE:To evaluate the efficacy and safety of sugarcane bagasse dietary fiber as an adjuvant therapy for improving quality of life in patients with stable chronic obstructive pulmonary disease(COPD).METHODS:This was a multicenter,randomized,double-blind,placebo-controlled trial.A total of196 participants were randomized into a trial group(treated with 6 g/day sugarcane bagasse plus conventional treatment,n = 98) and a control group(treated with placebo plus conventional treatment,n = 98).All efficacy analyses were performed according to the intention-to-treat(ITT) principle.A per-protocol analysis set(PPS) was used to analyze the cases that completed the clinical trial with good compliance.The trial period was 30 days,with a 6-month follow-up.Pre-and post-treatmentpulmonary symptom scores(cough,sputum,wheezing,and dyspnea) were recorded for both groups.The St.George's Respiratory Questionnaire(SGRQ) and the modified Medical Research Council(m MRC) dyspnea scale were assessed before treatment and at the end of the 6-month follow-up.RESULTS:The ITT population was 178 and the PPS population was 166.Post-treatment pulmonary clinical symptoms and severity of dyspnea(m MRC and SGRQ evaluation) were significantly improved in both the trial group and the control group(ITT and PPS:P < 0.05).However,there was no statistical difference between the two groups in post-treatment pulmonary symptoms and m MRC.There was a greater reduction in the SGRQ subscales of activity,effect and total score in the trial group compared with the control group(ITT and PPS:P < 0.01).There was no statistical difference in pre-and post-treatment safety variables in either group.CONCLUSION:Sugarcane bagasse combined with conventional treatment improved quality of life in patients with stable COPD.Sugarcane bagasse appears to be a safe herbal medicine with potential for treating patients with stable COPD when taken orally as an adjuvant therapy. | Liu Miao Zheng Fengjie Ni Lei Sun Yan Wu Ruohan Zhang Tianyu Zhang Jinchao Zhong Xianggen Li Yuhang | 2016 | Journal of Traditional Chinese Medicine2016，36，4： | 2 |
| 5 | Significance of mitochondrial activity in neurogenesis and neurodegenerative diseases显示文摘Mitochondria play a multidimensional role in the function and the vitality of the neurological system.From the generation of neural stem cells to the maintenance of neurons and their ultimate demise,mitochondria play a critical role in regulating our neural pathways'homeostasis,a task that is critical to our cognitive health and neurological well-being.Mitochondria provide energy via oxidative phosphorylation for the neurotransmission and generation of an action potential along the neuron's axon.This paper will first review and examine the molecular subtleties of the mitochondria's role in neurogenesis and neuron vitality,as well as outlining the impact of defective mitochondria in neural aging.The authors will then summarize neurodegenerative diseases related to either neurogenesis or homeostatic dysfunction.Because of the significant detriment neurodegenerative diseases have on the quality of life,it is essential to understand their etiology and ongoing molecular mechanics.The mitochondrial role in neurogenesis and neuron vitality is essential.Dissecting and understanding this organelle's role in the genesis and homeostasis of neurons should assist in finding pharmaceutical targets for neurodegenerative diseases. | Serra Ozgen Judith Krigman Ruohan Zhang Nuo Sun | 2022 | Neural Regeneration Research2022，17，4： | 2 |
| 6 | Highly efficient degradation of emerging contaminants by magnetic CuO@Fe_(x)O_(y) derived from natural mackinawite(FeS) in the presence of peroxymonosulfate显示文摘In this study,natural mackinawite (Fe S),a chalcophilic mineral,was utilized to prepare iron/copper bimetallic oxides (Cu^(O)@Fe_(x)O_(y)) by displacement plating and calcination process.Various characterization methods prove that Cu;is successfully coated on the surface of Fe S,which were further oxidized to Cu^(O),Fe_(3)O_(4)and/or Fe_(2)O_(3)during calcination process,respectively.Cu^(O)@Fe_(x)O_(y)performed highly efficient capacity to activate PMS for the degradation of various emerging pollutants including sulfamethoxazole(SMX),carbamazepine (CBZ),bisphenol A (BPA),2,4-dichlorophenol (2,4-DCP) and diclofenac (DCF) in aqueous solution.Complete removal of the above pollutants was observed after 8 min of Cu^(O)@Fe_(x)O_(y)/PMS treatment.Taking SMX as an example,the key parameters including Cu^(O)@Fe_(x)O_(y)dosage,PMS dosage and initial p H were optimized.The results show that the catalytic system can be worked in a wide p H range (3.0-9.0).The quenching experiments and electron spin resonance (ESR) test demonstrated that the main reactive oxygen species in Cu^(O)@Fe_(x)O_(y)/PMS system were hydroxyl radicals (^(·)OH) and sulfate radicals(SO_(4)^(·ˉ)),and SO_(4)^(·ˉ)was the primary reactive species.Besides,the influence of coexisting anions (i.e.,Cl^(ˉ),NO_(3)^(ˉ),HCO_(3)^(ˉ)and H_(2)PO_(4)^(ˉ)) for the degradation of SMX was explored.Cu^(O)@Fe_(x)O_(y)/PMS system can maintain good catalytic activity and reusability in different water bodies and long-term running.This work provided a green strategy to fabricate the efficient catalyst in PMS-based advanced oxidation processes. | Ruohan Zhang Maolian Chen Zhaokun Xiong Yong Guo Bo Lai | 2022 | Chinese Chemical Letters2022，33，2： | 1 |
| 7 | Health benefits from the rapid reduction in ambient exposure to air pollutants after China’s clean air actions:progress in efficacy and geographic equality显示文摘Clean air actions(CAAs)in China have been linked to considerable benefits in public health.However,whether the beneficial effects of CAAs are equally distributed geographically is unknown.Using high-resolution maps of the distributions of major air pollutants(fine particulate matter[PM_(2.5)]and ozone[O_(3)])and population,we aimed to track spatiotemporal changes in health impacts from,and geographic inequality embedded in,the reduced exposures to PM_(2.5)and O_(3)from 2013 to 2020.We used a method established by the Global Burden of Diseases Study.By analyzing the changes in loss of life expectancy(LLE)attributable to PM_(2.5)and O_(3),we calculated the gain of life expectancy(GLE)to quantify the health benefits of the air-quality improvement.Finally,we assessed the geographic inequality embedded in the GLE using the Gini index(GI).Based on risk assessments of PM_(2.5)and O_(3),during the first stage of CAAs(2013 to 2017),the mean GLE was 1.87 months.Half of the sum of the GLE was disproportionally distributed in about one quarter of the population exposed(GI 0.44).During the second stage of CAAs(2017 to 2020),the mean GLE increased to 3.94 months and geographic inequality decreased(GI 0.18).According to our assessments,CAAs were enhanced,from the first to second stages,in terms of not only preventing premature mortality but also ameliorating health inequalities.The enhancements were related to increased sensitivity to the health effects of air pollution and synergic control of PM_(2.5)and O_(3)levels.Our findings will contribute to optimizing future CAAs. | Tao Xue Ruohan Wang Meng Wang Yanying Wang Dan Tong Xia Meng Conghong Huang Siqi Ai Fangzhou Li Jingyuan Cao Mingkun Tong Xueqiu Ni Hengyi Liu Jianyu Deng Hong Lu Wei Wan Jicheng Gong Shiqiu Zhang Tong Zhu | 2024 | National Science Review2024，11，2： | 0 |
| 8 | Dynamic Routing of Multiple QoS-Required Flows in Cloud-Edge Autonomous Multi-Domain Data Center Networks显示文摘The 6th generation mobile networks(6G)network is a kind of multi-network interconnection and multi-scenario coexistence network,where multiple network domains break the original fixed boundaries to form connections and convergence.In this paper,with the optimization objective of maximizing network utility while ensuring flows performance-centric weighted fairness,this paper designs a reinforcement learning-based cloud-edge autonomous multi-domain data center network architecture that achieves single-domain autonomy and multi-domain collaboration.Due to the conflict between the utility of different flows,the bandwidth fairness allocation problem for various types of flows is formulated by considering different defined reward functions.Regarding the tradeoff between fairness and utility,this paper deals with the corresponding reward functions for the cases where the flows undergo abrupt changes and smooth changes in the flows.In addition,to accommodate the Quality of Service(QoS)requirements for multiple types of flows,this paper proposes a multi-domain autonomous routing algorithm called LSTM+MADDPG.Introducing a Long Short-Term Memory(LSTM)layer in the actor and critic networks,more information about temporal continuity is added,further enhancing the adaptive ability changes in the dynamic network environment.The LSTM+MADDPG algorithm is compared with the latest reinforcement learning algorithm by conducting experiments on real network topology and traffic traces,and the experimental results show that LSTM+MADDPG improves the delay convergence speed by 14.6%and delays the start moment of packet loss by 18.2%compared with other algorithms. | Shiyan Zhang Ruohan Xu Zhangbo Xu Cenhua Yu Yuyang Jiang Yuting Zhao | 2024 | Computers, Materials & Continua2024，78，2： | 0 |
| 9 | Synthesis of D-A typed AIE luminogens in isomeric architecture and their application in latent fingerprints imaging显示文摘Among the emitters in powder dusting to visualize the latent fingerprints(LFPs),aggregation-induced emission luminogens(AIEgens)are well employed for their high brightness and resistance to photobleaching.However,the serious background interference and low resolution still limit their fast development.Therefore,to further enhance the signal-to-noise ratio in LFPs imaging,especially to improve the analysis for level 3 details,donor-acceptor(D-A)typed AIEgens of DTPA-2,3-P,DTPA-2,5-P and DTPA-2,6-P are designed here.It is observed that strong emission covering from 450nm to 650nm can be obtained for all these molecules,especially that a high PLQY value of 10.06%in solids is achieved in DTPA-2,3-P.This is much higher than that of the other two cases(0.80%and 0.51%).By utilizing the DTPA-2,3-P in powder dusting,fluorescence imaging of LFPs can be clearly captured on both smooth and rough substrates.Moreover,confocal laser scanning microscope(CLSM)enables us to achieve high-resolution LFPs imaging in both 2D and 3D views,providing more detailed information of fingerprints pores in width,distance,distribution,and shapes.The results here demonstrate that highly emissive AIEgen of DTPA-2,3-P could be an excellent candidate for the visualization of fingerprints,thus providing the potential application in criminal investigation in the future. | Peijuan Zhang Qifei Shen Yu Zhou Fengyi He Bo Zhao Zhi Wang Ruohan Xu Yanzi Xu Zhiwei Yang Lingjie Meng Dongfeng Dang | 2023 | Chinese Chemical Letters2023，34，8： | 0 |
| 10 | The appearance of cytoplasmic cytochrome C precedes apoptosis during Drosophila salivary gland degradation显示文摘Apoptosis is an important process for organism development that functions to eliminate cell damage,maintain homeostasis,and remove obsolete tissues during morphogenesis.In mammals,apoptosis is accompanied by the release of cytochrome C(Cyt-c)from mitochondria to the cytoplasm.However,whether this process is conserved in the fruit fly,Drosophila melanogaster,remains controversial.In this study,we discovered that during the degradation of Drosophila salivary gland,the transcription of mitochondria apoptosis factors(MAPFs),Cyt-c,and death-associated APAF1-related killer(Dark)encoding genes are all upregulated antecedent to initiator and effector caspases encoding genes.The proteins Cyt-c and the active caspase 3 appear gradually in the cytoplasm during salivary gland degradation.Meanwhile,the Cyt-c protein colocates with mito-GFP,the marker indicating cytoplasmic mitochondria,and the change in mitochondrial membrane potential coincides with the appearance of Cyt-c in the cytoplasm.Moreover,impeding or promoting 20E-induced transcription factor E93 suppresses or enhances the staining of Cyt-c and the active caspase 3 in the cytoplasm of salivary gland,and accordingly decreases or increases the mitochondrial membrane potential,respectively.Our research provides evidence that cytoplasmic Cyt-c appears before apoptosis during Drosophila salivary gland degradation,shedding light on partial conserved mechanism in apoptosis between insects and mammals. | Shihui Long Wenxin Cao Yongyu Qiu Ruohan Deng Jiali Liu Lidan Zhang Renke Dong Fengxin Liu Sheng Li Haigang Zhao Na Li Kang Li | 2024 | Insect Science2024，31，1： | 0 |
| 11 | Transformation of Undesired Li_(2)CO_(3)into Lithiophilic Layer Via Double Replacement Reaction for Garnet Electrolyte Engineering显示文摘Garnet-type solid-state electrolytes(SSEs)are a remarkable Li-ion electrolyte for the realization of next-generation all-solid-state lithium batteries due to their excellent stability against Li metal as well as high ionic conductivities at room temperature.However,garnet electrolytes always contain undesired and hardly removable Li_(2)CO_(3) contaminations that have persistently large resistance and unstable interface contact with Li metal.This is a critical bottleneck for the practical application of garnet electrolytes.Here,we design a novel strategy to completely root out Li_(2)CO_(3) both inside and on the surface of garnet.This is achieved by a so-called double replacement reaction between Li_(2)CO_(3) and SiO_(2) during one-step hot press process for garnet electrolyte densification.It leads to in-situ transformation of LixSiOy(LSO)mostly locating around the grain boundaries of garnet.Due to the higher ion conductivity and better electrochemistry stability of LSO than Li_(2)CO_(3),the modified garnet electrolyte shows much improved electrochemical performance.Moreover,the wettability between modified garnet electrolyte and lithium metals was significantly enhanced in the absence of surface Li_(2)CO_(3).As a proof of concept,an assembled Li symmetric cell with modified garnet electrolyte displays a high critical current density(CCD)of 0.7 mA cm^(-2)and a low interfacial impedance(5Ωcm^(2))at 25℃.These results indicate that the upcycling of Li_(2)CO_(3)is a promising strategy to well-address the degradation and interfacial issue associated with garnet electrolytes. | Jiaxu Zhang Ruohan Yu Jun Li Huiyu Zhai Gangjian Tan Xinfeng Tang | 2022 | Energy & Environmental Materials2022，5，3： | 0 |
| 12 | Nowcasting and Forecasting Seasonal Influenza Epidemics—China,2022-2023显示文摘Background:Seasonal influenza resurged in China in February 2023,causing a large number of hospitalizations.While influenza epidemics occurred across China during the coronavirus disease 2019(COVID-19)pandemic,the relaxation of COVID-19 containment measures in December 2022 may have contributed to the spread of acute respiratory infections in winter 2022/2023.Methods:Using a mathematical model incorporating influenza activity as measured by influenza-like illness(ILI)data for northern and southern regions of China,we reconstructed the seasonal influenza incidence from October 2015 to September 2019 before the COVID-19 pandemic.Using this trained model,we predicted influenza activities in northern and southern China from March to September 2023.Results:We estimated the effective reproduction number Re as 1.08[95%confidence interval(CI):0.51,1.65]in northern China and 1.10(95%CI:0.55,1.67)in southern China at the start of the 2022-2023 influenza season.We estimated the infection attack rate of this influenza wave as 18.51%(95%CI:0.00%,37.78%)in northern China and 28.30%(95%CI:14.77%,41.82%)in southern China.Conclusions:The 2023 spring wave of seasonal influenza in China spread until July 2023 and infected a substantial number of people. | Zhanwei Du Zengyang Shao Xiao Zhang Ruohan Chen Tianmu Chen Yuan Bai Lin Wang Eric H.Y.Lau Benjamin J.Cowling | 2023 | China CDC weekly2023，5，49： | 0 |
| 13 | Activating Inert Sites in Cobalt Silicate Hydroxides for Oxygen Evolution through Atomically Doping显示文摘Metal silicate hydroxides have been recognized as efficient oxygen evolution reaction(OER)electrocatalysts,yet tailoring of their intrinsic activity remains confused.Herein,Fe had been incorporated into cobalt silicate hydroxide nanosheets and the resulted material achieves a competitive OER catalytic activity.It is found that the doping state obviously affects the electrical transport property.Specifically,highly dispersed Fe atoms(low-concentration Fe doping)trigger slight electron transfer to Co atoms while serried Fe(highconcentration Fe doping)attract vast electrons.By introducing 6 at.%Fe doping,partial relatively inert Co sites are activated by atomically dispersed Fe,bearing an optimal metal 3d electronic occupation and adsorption capacity to oxygen intermediate.The introduced Co-O-Fe unit trigger the p-donation effect and decrease the number of electrons in p*-antibonding orbitals,which enhance the Fe-O covalency and the structural stability.As a result,the sample delivers a low overpotential of 293 mV to achieve a current density of 10 mA cm^(-2).This work clarifies the superiority of atomically dispersed doping state,which is of fundamental interest to the design of doped catalyst. | Jiexin Zhu Lixue Xia Wenxuan Yang Ruohan Yu Wei Zhang Wen Luo Yuhang Dai Wei Wei Liang Zhou Yan Zhao Liqiang Mai | 2022 | Energy & Environmental Materials2022，5，2： | 0 |
| 14 | The effect of cylindrospermopsin on the bacterioplankton community:a microcosm experiment on water from Dishui Lake,Shanghai,China显示文摘Eutrophication and climate warming have intensified the global expansion of invasive cyanobacteria such as Cylindrospermopsis spp.and Chrysosporum spp.Cylindrospermopsin(CYN)produced by species of the latter two genera may harm phytoplankton,zooplankton,and fishes.However,effects of CYN on the bacterioplankton community have not been studied.Based on high-throughput sequencing,we explored the effect of CYN on the structure and function of the bacterioplankton community by adding pure CYN to in-situ water collected from a brackish coastal shallow lake:Dishui Lake,China.We found that most bacterioplankton taxa had a certain tolerance potential to CYN,but that high concentrations of CYN(40μg/L)caused a significant decrease in microbial abundance and functional groups.Of the dominant phyla,Actinobacteria had the strongest tolerance to CYN.Network analysis indicated that CYN caused shifts in the community structure of the bacterioplankton,reducing community stability and structural complexity.High CYN concentrations also reduced the correlation between the different bacterioplankton groups,and the abundances of some bacterial taxa associated with the denitrification function and the process of carbon transfer in the microbial food web were inhibited.Our study provide s new insight into the response of the bacterioplankton communities to harmful algal toxins produced by cyanobacteria. | Sicheng YIN Ruohan HUANG Erik JEPPESEN Lijing CHEN Liqing WANG Xin FANG Wei ZHANG | 2022 | Journal of Oceanology and Limnology2022，40，5： | 0 |
| 15 | Design of High-Contrast Mechanochromic Materials Based on Aggregation-Induced Emissive Pyran Derivatives Guided by Polymorph Predictions显示文摘High-contrast mechanochromic(MC)materials are prominent candidates for sensor,security,and memory applications;however,the development of materials with a large luminescence change(Δλem>100 nm)under external stimuli is challenging.Considering that polymorphic molecules usually exhibit reversible mechanochromism,polymorph prediction is adopted for thefirst time to guide the design of high-contrastMC materials in this study.We designed and synthesized a series of donor–π–acceptor pyran derivatives bearing different electron donors and acceptors as model systems.The polymorph prediction indicated that 4-dicyanomethylene-2,6-distyryl-4H-pyran and 4H-pyran-4-one derivatives had the potential to crystallize in both monomer andπ-dimer aggregates,while barbituric acid-based compound tended to pack tightly in all aggregated states.The experimental results agreed well with the prediction that the derivatives potentially possessing both monomer andπ-dimer aggregate structures exhibit excellent MC behavior,whereas the fluorescence difference for the barbituric acid-based compounds is minimal.Moreover,a compound with an excellent fluorescence difference of three colors during reversible mechanochromism was chosen as the candidate for an optical recording material and security ink.This work proposes an effective method to guide the design of stimuli-responsive materials,which may open promising avenues for the development of high-contrast MC molecules. | Wen Wang Ruohan Li Shuzhang Xiao Qilin Xing Xia Yan Jiayu Zhang Xinghong Zhang Haichuang Lan Tao Yi | 2022 | CCS Chemistry2022，4，3： | 0 |
| 16 | A Derivative Matrix-Based Covert Communication Method in Blockchain显示文摘The data in the blockchain cannot be tampered with and the users are anonymous,which enables the blockchain to be a natural carrier for covert communication.However,the existing methods of covert communication in blockchain suffer from the predefined channel structure,the capacity of a single transaction is not high,and the fixed transaction behaviors will lower the concealment of the communication channel.Therefore,this paper proposes a derivation matrix-based covert communication method in blockchain.It uses dual-key to derive two types of blockchain addresses and then constructs an address matrix by dividing addresses into multiple layers to make full use of the redundancy of addresses.Subsequently,to solve the problem of the lack of concealment caused by the fixed transaction behaviors,divide the rectangular matrix into square blocks with overlapping regions and then encrypt different blocks sequentially to make the transaction behaviors of the channel addresses match better with those of the real addresses.Further,the linear congruence algorithm is used to generate random sequence,which provides a random order for blocks encryption,and thus enhances the security of the encryption algorithm.Experimental results show that this method can effectively reduce the abnormal transaction behaviors of addresses while ensuring the channel transmission efficiency. | Xiang Zhang Xiaona Zhang Xiaorui Zhang Wei Sun Ruohan Meng Xingming Sun | 2023 | Computer Systems Science & Engineering2023，46，7： | 0 |
| 17 | Inhibition of aryl hydrocarbon receptor signaling promotes the terminal differentiation of human erythroblasts显示文摘The aryl hydrocarbon receptor(AHR)plays an important role during mammalian embryo development.Inhibition of AHR signaling promotes the development of hematopoietic stem/progenitor cells.AHR also regulates the functional maturation of blood cells,such as T cells and megakaryocytes.However,little is known about the role of AHR modulation during the development of erythroid cells.In this study,we used the AHR antagonist StemRegenin 1(SR1)and the AHR agonist 2,3,7,8-tetrachlorodibenzo-p-dioxin during different stages of human erythropoiesis to elucidate the function of AHR.We found that antagonizing AHR signaling improved the production of human embryonic stem cell derived erythrocytes and enhanced erythroid terminal differentiation.RNA sequencing showed that SR1 treatment of proerythroblasts upregulated the expression of erythrocyte differentiation-related genes and downregulated actin organization-associated genes.We found that SR1 accelerated F-actin remodeling in terminally differentiated erythrocytes,favoring their maturation of the cytoskeleton and enucleation.We demonstrated that the effects of AHR inhibition on erythroid maturation were associated with F-actin remodeling.Our findings help uncover the mechanism for AHRmediated human erythroid cell differentiation.We also provide a new approach toward the large-scale production of functionally mature human pluripotent stem cell-derived erythrocytes for use in translational applications. | Yijin Chen Yong Dong Xulin Lu Wanjing Li Yimeng Zhang Bin Mao Xu Pan Xiaohong Li Ya Zhou Quanming An Fangxin Xie Shihui Wang Yuan Xue Xinping Cai Mowen Lai Qiongxiu Zhou Yan Yan Ruohan Fu Hong Wang Tatsutoshi Nakahata Xiuli An Lihong Shi Yonggang Zhang Feng Ma | 2022 | Journal of Molecular Cell Biology2022，14，2： | 0 |
| 18 | LKAW: A Robust Watermarking Method Based on Large Kernel Convolution and Adaptive Weight Assignment显示文摘Robust watermarking requires finding invariant features under multiple attacks to ensure correct extraction.Deep learning has extremely powerful in extracting features,and watermarking algorithms based on deep learning have attracted widespread attention.Most existing methods use 3×3 small kernel convolution to extract image features and embed the watermarking.However,the effective perception fields for small kernel convolution are extremely confined,so the pixels that each watermarking can affect are restricted,thus limiting the performance of the watermarking.To address these problems,we propose a watermarking network based on large kernel convolution and adaptive weight assignment for loss functions.It uses large-kernel depth-wise convolution to extract features for learning large-scale image information and subsequently projects the watermarking into a highdimensional space by 1×1 convolution to achieve adaptability in the channel dimension.Subsequently,the modification of the embedded watermarking on the cover image is extended to more pixels.Because the magnitude and convergence rates of each loss function are different,an adaptive loss weight assignment strategy is proposed to make theweights participate in the network training together and adjust theweight dynamically.Further,a high-frequency wavelet loss is proposed,by which the watermarking is restricted to only the low-frequency wavelet sub-bands,thereby enhancing the robustness of watermarking against image compression.The experimental results show that the peak signal-to-noise ratio(PSNR)of the encoded image reaches 40.12,the structural similarity(SSIM)reaches 0.9721,and the watermarking has good robustness against various types of noise. | Xiaorui Zhang Rui Jiang Wei Sun Aiguo Song Xindong Wei Ruohan Meng | 2023 | Computers, Materials & Continua2023，，4： | 0 |
| 19 | Bi nanoparticles encapsulated in nitrogen-doped carbon as a long-life anode material for magnesium batteries显示文摘Bismuth has garnered significant interest as an anode material for magnesium batteries(MBs) because of its high volumetric specific capacity and low working potential. Nonetheless, the limited cycling performance(≤100 cycles) limits the practical application of Bi as anode for MBs. Therefore, the improvement of Bi cycling performance is of great significance to the development of MBs and is also full of challenges. Here, Bi nanoparticles encapsulated in nitrogen-doped carbon with single-atom Bi embedded(Bi@NC) are prepared and reported as an anode material for MBs. Bi@NC demonstrates impressive performance, with a high discharge capacity of 347.5 mAh g^(-1) and good rate capability(206.4 mAh g^(-1)@500 mA g^(-1)) in a fluoride alkyl magnesium salt electrolyte. In addition, Bi@NC exhibits exceptional long-term stability, enduring 400 cycles at 500 mA g^(-1). To the best of our knowledge, among reported Bi and Bi-based compounds for MBs, Bi@NC exhibits the longest cycle life in this work. The magnesium storage mechanism of Bi@NC is deeply studied through X-ray diffraction, transmission electron microscopy and X-ray photoelectron spectroscopy. This work provides some guidance for further improving the cycling performance of other alloy anodes in MBs. | Junjun Wang Ruohan Yu Jianxiang Wang Juncai Long Fan Qiao Lei Zhang Guanjie He Qinyou An Liqiang Mai | 2023 | Journal of Magnesium and Alloys2023，11，11： | 0 |
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