| 1 | Low-Complexity Signal Detection Based on Relaxation Iteration Method in Massive MIMO Systems显示文摘Minimum mean square error(MMSE) detection algorithm can achieve nearly optimal performance when the number of antennas at the base station(BS) is large enough compared to the number of users. But the traditional MMSE involves complicated matrix inversion. In this paper, we propose a modified MMSE algorithm which exploits the channel characteristics occurring in massive multiple-input multipleoutput(MIMO) channels and the relaxation iteration(RI) method to avoid the matrix inversion. A proper initial solution is given to accelerate the convergence speed. In addition, we point out that the channel estimation scheme used in channel hardening-exploiting message passing(CHEMP) receiver is very appropriate for our proposed detection algorithm. Simulation results verify that the proposed algorithm can achieve very close performance of the traditional MMSE algorithm with a small number of iterations. | GUO Ruohan LI Xiaohui FU Weihong HEI Yongqiang | 2015 | China Communications2015，12，S1： | 3 |
| 2 | Inhibition of aryl hydrocarbon receptor signaling promotes the terminal differentiation of human erythroblasts显示文摘The aryl hydrocarbon receptor(AHR)plays an important role during mammalian embryo development.Inhibition of AHR signaling promotes the development of hematopoietic stem/progenitor cells.AHR also regulates the functional maturation of blood cells,such as T cells and megakaryocytes.However,little is known about the role of AHR modulation during the development of erythroid cells.In this study,we used the AHR antagonist StemRegenin 1(SR1)and the AHR agonist 2,3,7,8-tetrachlorodibenzo-p-dioxin during different stages of human erythropoiesis to elucidate the function of AHR.We found that antagonizing AHR signaling improved the production of human embryonic stem cell derived erythrocytes and enhanced erythroid terminal differentiation.RNA sequencing showed that SR1 treatment of proerythroblasts upregulated the expression of erythrocyte differentiation-related genes and downregulated actin organization-associated genes.We found that SR1 accelerated F-actin remodeling in terminally differentiated erythrocytes,favoring their maturation of the cytoskeleton and enucleation.We demonstrated that the effects of AHR inhibition on erythroid maturation were associated with F-actin remodeling.Our findings help uncover the mechanism for AHRmediated human erythroid cell differentiation.We also provide a new approach toward the large-scale production of functionally mature human pluripotent stem cell-derived erythrocytes for use in translational applications. | Yijin Chen Yong Dong Xulin Lu Wanjing Li Yimeng Zhang Bin Mao Xu Pan Xiaohong Li Ya Zhou Quanming An Fangxin Xie Shihui Wang Yuan Xue Xinping Cai Mowen Lai Qiongxiu Zhou Yan Yan Ruohan Fu Hong Wang Tatsutoshi Nakahata Xiuli An Lihong Shi Yonggang Zhang Feng Ma | 2022 | Journal of Molecular Cell Biology2022，14，2： | 0 |
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