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| 1 | Ages of the Laocheng Granitoids and Crustal Growth in the South Qinling Tectonic Domain,Central China:Zircon U-Pb and Lu-Hf Isotopic Constraints显示文摘Laocheng granitoid pluton 位于 Qinling erogenic 带的南方 Qinling 构造领域,南部的 Shaanxi 省,并且由石英闪长岩, granodiorite 和 monzogranite 主要组成。LA-ICP-MS 锆石 U-Pb 与阴极射线发光图象一起,同位素的标明日期表明石英闪长岩和 granodiorite 是从 220 妈的 emplaced 到 216 妈,当 monzogranite 是在 210 妈的 emplaced 时。在原处,锆石 Hf 同位素的分析证明从 8.1 的石英闪长岩和到 +1.3 的 granodiorite 范围的 Hf (t)价值,和单个阶段的 Hf 从 809 妈为年龄建模到 1171 妈,当 monzogranite 的 Hf (t)价值是 14.5 到 +16.7 和单个阶段的 Hf 时,从 189 妈为年龄建模到 1424 妈。这些 Hf 同位素的特征表明石英闪长岩, granodiorite 和 monzogranite 从混合从弄空的披风和更低的大陆的部分融化导出的岩浆被形成外壳的材料,并且在 Neoproterozoic ( 800 妈)和 Indosinian ( 210 妈)期间有大陆人外壳生长的二个阶段分别地,时代在 Qinling orogrnic 的南方 Qinling 构造领域系上带子,华中。 | YANG Pengtao LIU Shuwen LI Qiugen ZHANG Fan WANG Zongqi WANG Dongsheng WANG Ruiting YAN Quanren YAN Zhen | 2011 | Acta Geologica Sinica(English Edition)2011，85，4： | 15 |
| 2 | Mechanistic and therapeutic advances in non-alcoholic fatty liver disease by targeting the gut microbiota显示文摘Non-alcoholic fatty liver disease (NAFLD)is one of the most common metabolic diseases currently in the context of obesity worldwide,which contains a spectrum of chronic liver diseases,including hepatic steatosis, non-alcoholic steatohepatitis and hepatic carcinoma.In addition to the classical 'Two-hit'theory,NAFLD has been recognized as a typical gut microbiota-related disease because of the intricate role of gut microbiota in maintaining human health and disease formation.Moreover,gut microbiota is even regarded as a 'metabolic organ'that play complementary roles to that of liver in many aspects.The mechanisms underlying gut microbiota-mediated development of NAFLD include modulation of host energy metabolism,insulin sensitivity, and bile acid and choline metabolism.As a result,gut microbiota have been emerging as a novel therapeutic target for NAFLD by manipulating it in various ways,including probiotics,prebiotics,synbiotics,antibiotics,fecal microbiota transplantation,and herbal components.In this review,we summarized the most recent advances in gut microbiota-mediated mechanisms,as well as gut microbiota-targeted therapies on NAFLD. | Ruiting Han Junli Ma Houkai Li | 2018 | Frontiers of Medicine2018，12，6： | 11 |
| 3 | Design and fabrication of a SiN-Si dua卜layer optical phased array chip显示文摘A SiN-Si dual-layer optical phased array(OPA)chip is designed and fabricated.It combines the low loss of SiN with the excellent modulation performance of Si,which improves the performance of Si single-layer OPA.A novel optical antenna and an improved phase modulation method are also proposed,and a two dimensional scanning range of 96°×14°is achieved,which makes the OPA chip more practical. | PENGFEI WANG GUANGZHEN LUO YANG XU YAJIE LI YANMEI SU JIANBIN MA RUITING WANG ZHENGXIA YANG XULIANG ZHOU YEJIN ZHANG JIAOQING PAN | 2020 | Photonics Research2020，8，6： | 5 |
| 4 | Engineering Mesoporous Structure in Amorphous Carbon Boosts Potassium Storage with High Initial Coulombic Efficiency显示文摘Amorphous carbon shows great potential as an anode material for high-performance potassium-ion batteries;however,its abundant defects or micropores generally capture K ions,thus resulting in high irreversible capacity with low initial Coulombic efficiency(ICE)and limited practical application.Herein,pore engineering via a facile self-etching strategy is applied to achieve mesoporous carbon(meso-C)nanowires with interconnected framework.Abundant and evenly distributed mesopores could provide short K^+ pathways for its rapid diffusion.Compared to microporous carbon with highly disordered structure,the meso-C with Zn-catalyzed short-range ordered structure enables more K^+to reversibly intercalate into the graphitic layers.Consequently,the mesoC shows an increased capacity by ~100 mAh g^-1 at 0.1 A g^-1,and the capacity retention is 70.7% after 1000 cycles at 1 A g^-1.Multiple in/ex situ characterizations reveal the reversible structural changes during the charging/discharging process.Particularly,benefiting from the mesoporous structure with reduced specific surface area by 31.5 times and less defects,the meso-C generates less irreversible capacity with high ICE up to 76.7%,one of the best reported values so far.This work provides a new perspective that mesopores engineering can effectively accelerate K^+ diffusion and enhance K^+ adsorption/intercalation storage. | Ruiting Guo Xiong Liu Bo Wen Fang Liu Jiashen Meng Peijie Wu Jinsong Wu Qi Li Liqiang Mai | 2020 | Nano-Micro Letters2020，12，11： | 5 |
| 5 | Geochemistry and Zircon U–Pb–Hf Isotopic Systematics of the Sanchahe Quartz Monzonite Intrusion in the North Qinling Tectonic Zone, Central China: Implications for its Petrogenesis and Tectonic Setting显示文摘The Sanchahe quartz monzonite intrusion is situated in the middle segment of the North Qinling tectonic belt, Central China mainland, and consists chiefly of sanukitoid–like and granodioritic-monzogranitic rocks. The sanukitoid–like rocks are characterized by quartz monzonites, which display higher Mg#(55.0–59.0), and enrichments in Na2 O+K2 O(7.28–8.94 %), Ni(21-2312 ppm), Cr(56-4167 ppm), Sr(553-923 ppm), Ba(912-1355 ppm) and LREE((La/Yb)N =9.47–15.3), from negative to slightly positive Eu anomalies(δEu=+0.61 to +1.10), but also depletion in Nb, Ta and Ti. The granodioritic-monzogranitic rocks diaplay various Mg#of 6.00-53.0, high Na2 O+K2 O(7.20– 8.30%), Sr(455–1081 ppm) and(La/Yb)N(27.6–47.8), with positive Eu anomalies(δEu=1.03–1.57) and depleted Nb, Ta and Ti. Laser ablation inductively coupled plasma mass spectrometry(LA-ICPMS) zircon U-Pb isotopic dating reveals that the sanukitoid-like rocks were emplaced at two episodes of magmatism at 457±3 Ma and 431±2 Ma, respectively. The monzogranites were emplaced at 445±7Ma. Sanukitoid–like rocks have their εHf(t) values ranging from +0.3 to +15.1 with Hf–depleted mantle model ages of 445 to 1056 Ma, and the monzogranite shows its εHf(t) values ranging from 21.6 to +10.8 with Hf–depleted mantle model ages of 635 to 3183 Ma. Petrological, geochemical and zircon Lu –Hf isotopic features indicate that the magmatic precursor of sanukitoid–like rocks was derived from partial melting of the depleted mantle wedge materials that were metasomatized by fluids and melts related to subduction of oceanic slab, subsequently the sanukitoid magma ascended to crust level. This emplaced mantle magma caused partial melting of crustally metamorphosed sedimentary rocks, and mixing with the crustal magma, and suffered fractional crystallization, which lead to formations of quartz monzonites. However, the magmatic precursor of the granodioritic-monzogranitic rocks were derived from partial melting of subducted oceanic slab basalts. Integrated previous investigation for the adackitic rocks in the south of the intrusion, the Sanchahe intrusion signed that the North Qinling tectonic zone was developed in an early Paleozoic transitionally tectonic background from an island arc to back–arc. | YAN Ming LIU Shuwen LI Qiugen ZHANG Wanyi YANG Pengtao YAN Zhen WANG Ruiting WANG Wei GUO Rongrong | 2014 | Acta Geologica Sinica(English Edition)2014，88，1： | 3 |
| 6 | Synthesis,Characterization and Electromagnetic Studies on Nanocrystalline Nickel Zinc Ferrite by Polyacrylamide Gel显示文摘Nanocrystalline 镍锌铁酸盐粉末(Ni_xZni_(1-x ) Fe2O4,为 x=0 的 A,为 x=0.2 的 B,为 x=0.5 的 C,为 x-0.8 的 D 和为 x=1 的 E ) 被聚丙烯酰氨综合胶化方法。X 光检查衍射(XRD ) ,传播电子显微镜学(TEM ) 和波导被用来描绘作文。弄干的胶化粉末是非结晶的 XRD 结果表演,和特征尖晶石Ni_( 0.5 )Zn_( 0.5 ) Fe2O4 达到顶点在胶化为锻烧的温度是的 1 h.When 在 400 °C 被锻烧以后,出现 600 和 800 °C ,平均谷物尺寸被是 10 和 30 nm 的 TEM 识别, respectively.The Ni_xZn_( 1-x ) Fe2O4 粉末在Ni^(2+)离子的增加满足的 8.2-11.0GHz .With 的频率范围有绝缘的损失和磁性的损失,当时,绝缘的参数(epsilon')和Ni_xZn_( 1-x ) Fe2O4 粉末的渗透(mu')减少绝缘的损失( epsilon “),磁性的损失(亩”)并且思考损失增加。 | Ruiting MA Yi WANG Yanwen TIAN Chunli ZHANG Xikun LI | 2008 | Journal of Materials Science & Technology2008，24，3： | 2 |
| 7 | Flow behavior modeling of the 7050 aluminum alloy at elevated temperatures considering the compensation of strain显示文摘 | Jiang Li Fuguo Li Jun Cai Ruiting Wang Zhanwei Yuan Fengmei Xue | 2012 | Materials and Design2012，，： | 2 |
| 8 | Effective suppression of the photodarkening effect in high-power Yb-doped fiber amplifiers by H2 loading显示文摘The radical suppression of the photodarkening effect and laser performance deterioration via H2 loading were demonstrated in high-power Yb-doped fiber(YDF)amplifiers.The photodarkening loss at equilibrium was114.4 d B/m at 702 nm in the pristine fiber,while it vanished in the H2-loaded fiber.To obtain a deeper understanding of the impact of photodarkening on laser properties,the evolution of the mode instability threshold and output power in fiber amplifiers was investigated.After pumping for 300 min,the mode instability threshold of the pristine fiber dropped from 770 to 612 W,and the periodic fluctuation of the output power became intense,finally reaching 100 W.To address the detrimental effects originating from photodarkening,H2 loading was applied in contrast experiments.The output power remained stable,and no sign of mode instability was observed in the H2-loaded fiber.Moreover,the transmittance at 638 nm confirmed the absence of the photodarkening effect.The results pave the way for the further development of high-power fiber lasers. | RUITING CAO GUI CHEN YISHA CHEN ZHILUN ZHANG XIANFENG LIN BIN DAI LUYUN YANG JINYAN LI | 2020 | Photonics Research2020，8，3： | 2 |
| 9 | Transcriptome and QTL analyses reveal candidate genes for fiber quality in Upland cotton显示文摘With increasing demand for high-quality cotton,it is desirable to identify genes involved in fiber development for molecular improvement of cotton.In this study,780 differentially expressed genes(DEGs)were identified in developing fibers at 10 days post-anthesis(DPA)in Gossypium hirsutum acc.DH962 and G.hirsutum cv.Jimian 5 using RNA-seq.Of 15 stable QTL for fiber quality identified in the same two parents in previous studies,4,3,6,1,and 1 QTL were associated with fiber length(FL),fiber strength(FS),micronaire(MIC),fiber elongation(FE)and fiber length uniformity ratio(FU),respectively.Integration of DEGs and QTL allowed the identification of 31 genes in 9 QTL regions,of which 25 were highly expressed in fibers based on the transcriptome datasets and 9 were preferentially expressed in different stages of fiber development.Gh_A01G0453(GhDTX19),Gh_D07G1581 and Gh_D04G0942 were expressed specifically in 5 and 10 DPA fibers,with Gh_D04G0942 showing low expression in other tissues except pistil.Gh_D07G1799(GhGAUT9),Gh_D11G0326(GhVPS29),Gh_D11G0333(GhTCP14),and Gh_D11G0334(GhNRP2)were preferentially expressed in 5 or 10 DPA fibers;Gh_A01G0397(GhABCG10)and Gh_D07G1744 were expressed specifically in 20 and 25 DPA fibers.These results suggest candidate genes for molecular improvement of cotton fiber quality. | Hantao Wang Ruiting Zhang Chao Shen Ximei Li De Zhu Zhongxu Lin | 2020 | The Crop Journal2020，8，1： | 2 |
| 10 | Post-mortem tissue proteomics reveals the pathogenesis of multi-organ injuries of COVID-19显示文摘Multi-organ injuries are a major complication of severe Coronavirus Disease 2019(COVID-19).However,its pathogenesis is barely understood.Herein;we profile host responses to fatal SARS-CoV-2 infection by performing quantitative proteomics of 19 post-mortem samples of 8 different organs or tissues,including lungs,liver,intestine,kidney;spleen,brain,heart and muscle,from 3 deceased COVID-19 victims during the first wave of the pandemic(Supplementary Fig.S1A and B,Tables SI-S3). | Yang Qiu Di Wu Wanshan Ning Jiqian Xu Ting Shu Muhan Huang Rong Chen Jiancheng Zhang Yang Han Qingyu Yang Ruiting Li Xiaobo Yang Yaxin Wang Xiaojing Zou Shangwen Pan Chaolin Huang Yu Xue You Shang Xi Zhou | 2021 | National Science Review2021，8，11： | 1 |
| 11 | The relationship of mantle-derived fluids to gold metallogenesis in the Jiaodong Peninsula: Evidence from D–O–C–S isotope systematics显示文摘 | Jingwen Mao Yitian Wang Houmin Li Franco Pirajno Changqing Zhang Ruiting Wang | 2007 | Ore Geology Reviews2007，，3： | 1 |
| 12 | The red palm weevil, Rhynchophorus ferrugineus (Coleoptera: Curculionidae), newly reported from Zhejiang, China and update of geographical distribution 显示文摘 | Yuezhong Li Zeng-Rong Zhu Ruiting Ju | 2009 | Florida Entomologist2009，92，2： | 1 |
| 13 | A global synthesis of the effectiveness and ecological impacts of management interventions for Spartina species显示文摘Invasions by Spartina species pose serious threats to global coastal ecosystems.Although many studies have examined the effectiveness and ecological impacts of invasive Spartina management,no comprehensive global synthesis has been conducted to assess the effects of management on Spartina per se and on wider non-targets.Here,we conducted a global meta-analysis of 3,459 observations from 102 studies to quantify the effects of different management interventions(physical,chemical,biological,and integrated control)on Spartina per se and native biodiversity and environments.We found that physical measures quickly suppressed Spartina but that their effectiveness declined over time.By contrast,chemical measures decreased the abundance and growth of Spartina to a lesser degree in the early stage,but the effectiveness increased over time.Different management measures did not significantly decrease the diversity of native biota on the whole,but native-plant diversity significantly decreased with time after physical control.Different management measures did not affect abiotic factors differently.These results support the use of chemical measures to control invasive Spartina,although their effectiveness would depend on the time since the management intervention.Addressing the problem of Spartina regrowth following physical control requires improved techniques.We hold that initial states of invaders and subsequent environmental changes after management interventions should be weighed in evaluating control efficacy. | Shengyu Wang Philip A.Martin Yan Hao William J.Sutherland Gorm E.Shackelford Jihua Wu Ruiting Ju Wenneng Zhou Bo Li | 2023 | Frontiers of Environmental Science & Engineering2023，17，11： | 1 |
| 14 | Oral nano-formulation improves pancreatic islets dysfunction via lymphatic transport for antidiabetic treatment显示文摘Type 2 diabetes mellitus(T2DM)therapy is facing the challenges of long-term medication and gradual destruction of pancreatic isletβ-cells.Therefore,it is timely to develop oral prolonged action formulations to improve compliance,while restoringβ-cells survival and function.Herein,we designed a simple nanoparticle with enhanced oral absorption and pancreas accumulation property,which combined apical sodiumdependent bile acid transporter-mediated intestinal uptake and lymphatic transportation.In this system,taurocholic acid(TCA)modified poly(lactic-co-glycolic acid)(PLGA)was employed to achieve pancreas location,hydroxychloroquine(HCQ)was loaded to execute therapeutic efficacy,and 1,2-dilauroyl-sn-glycero-3-phosphocholine(DLPC)was introduced as stabilizer together with synergist(PLGA-TCA/DLPC/HCQ).In vitro and in vivo results have proven that PLGA-TCA/DLPC/HCQ reversed the pancreatic islets damage and dysfunction,thus impeding hyperglycemia progression and restoring systemic glucose homeostasis via only once administration every day.In terms of mechanism PLGA-TCA/DLPC/HCQ ameliorated oxidative stress,remodeled the inflammatory pancreas microenvironment,and activated PI3K/AKT signaling pathway without obvious toxicity.This strategy not only provides an oral delivery platform for increasing absorption and pancreas targetability but also opens a new avenue for thorough T2DM treatment. | Lin Hou Xueyuan Peng Ruiting Wang Yifei Wang Hong Li Huijuan Zhang Yun Zhang Zhenzhong Zhang | 2023 | Acta Pharmaceutica Sinica B2023，13，7： | 1 |
| 15 | Effects of temperature on the development and population growth of the sycamore lace bug, Corythucha ciliata 显示文摘 | JU Ruiting WANG Feng LI Bo | 2011 | Journal of Insect Science2011，11，1： | 1 |
| 16 | Rapid cold hardening increases cold and chilling tolerances more than acclimation in the adults of the sycamore lace bug, Corythucha ciliata ( Say ) ( Hemiptera: Tingidae) 显示文摘 | JU Ruiting XIAO Yuyu LI Bo | 2011 | Journal of Insect Physiology2011，57，11： | 1 |
| 17 | Niobium oxyphosphate nanosheet assembled two-dimensional anode material for enhanced lithium storage显示文摘The development of high-capacity and high-rate anodes has become an attractive endeavor for achieving high energy and power densities in lithium-ion batteries(LIBs).Herein,a new-type anode material of reduced graphene oxide(rGO) supported niobium oxyphosphate(NbOPO_4) nanosheet assembled twodimensional composite material(NbOPO_4/rGO) is firstly fabricated and presented as a promising highperformance LIB anode material.In-depth electrochemical analyses and in/ex situ characterizations reveal that the intercalation-conversion reaction takes place during the first discharge process,followed by the reversible redox process between amorphous NbPO_4 and Nb which contributes to the reversible capacity in the subsequent cycles.Meanwhile,the lithiation-generated Li3 PO_4,behaving as a good lithium ion conductor,facilitates ion transport.The rGO support further regulates the structural and electron/ion transfer properties of NbOPO_4/rGO composite compared to neat NbOPO_4, resulting in greatly enhanced electrochemical performances.As a result,NbOPO_4/rGO as a new-type LIB anode material achieves a high capacity of 502.5 mAh g^(-1) after 800 cycles and outstanding rate capability of 308.4 mAh g^(-1) at 8 A g^(-1).This work paves the way for the deep understanding and exploration of phosphate-ba sed high-efficiency anode materials for LIBs. | Bo Wen Ruiting Guo Xiong Liu Wen Luo Qiu He Chaojiang Niu Jiashen Meng Qi Li Yan Zhao Liqiang Mai | 2021 | Journal of Energy Chemistry2021，30，2： | 1 |
| 18 | Examination of the Anaerobic Growth of Campylobacter concisus Strains显示文摘 | Hoyul Lee Rena Ma Michael C. Grimm Stephen M. Riordan Ruiting Lan Ling Zhong Mark Raftery Li Zhang Ana C. Gales | 2014 | International Journal of Microbiology2014，，： | 1 |
| 19 | Dual-AAV split prime editor corrects the mutation and phenotype in mice with inherited retinal degeneration显示文摘The prime editor(PE)can edit genomes with almost any intended changes,including all 12 possible types of base substitutions,small insertions and deletions,and their combinations,without the requirement for double strand breaks or exogenous donor templates.PE demonstrates the possibility of correcting a variety of disease-causing mutations and might expand the therapeutic application of gene editing.In this study,PE was optimized based on a dual-adeno-associated virus(AAV)split-intein system in vitro by screening different split sites and split inteins.We found that splitting PE before amino acid 1105(Ser)of SpCas9 with Rma intein resulted in the highest on-target editing.The orientations of pegRNA and nicking sgRNA in the AAV vector were further optimized.To test the in vivo performance of the optimized dual-AAV split-PE3,it was delivered by subretinal injection in rd12 mice with inherited retinal disease Leber congenital amaurosis.The prime editors corrected the pathogenic mutation with up to 16%efficiency in a precise way,with no detectable off-target edits,restored RPE65 expression,rescued retinal and visual function,and preserved photoceptors.Our findings establish a framework for the preclinical development of PE and motivate further testing of PE for the treatment of inherited retinal diseases caused by various mutations. | Kaiqin She Yi Liu Qinyu Zhao Xiu Jin Yiliu Yang Jing Su Ruiting Li Li Song Jianlu Xiao Shaohua Yao Fang Lu Yuquan Wei Yang Yang | 2023 | Signal Transduction and Targeted Therapy2023，8，3： | 1 |
| 20 | The red palm weevil, Rhynchophorus ferrugineus (Coleoptera: Curculionidae),newly reported from Zhejiang, China and update of geographical distribution显示文摘 | Yuezhong Li Zeng-Rong Zhu Ruiting Ju | 2009 | Florida Entomologist2009，92，2： | 1 |
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