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| 1 | Graphene oxide as a water transporter promoting germination of plants in soil显示文摘Graphene 氧化物(去) 是生纳入基础飞机并且到 graphene 格子的边的各种各样的包含氧的功能的组的 graphene 衍生物,因此,众多的恐水病的 sp 2 在聚类的唯一的结构在吸水的 sp 3 公司矩阵以内被孤立。在这研究,吸水的性质和搬运水的性质去被利用支持工厂的萌芽和生长。它被发现那低剂量变显著地在土壤支持了菠菜和细香葱的萌芽。包含氧的功能的组变镇定水,和搬运的恐水病的 sp 2 领域流水到种子加速植物的萌芽。在之间的强壮的相互作用去,稳定的土壤谷物的表面在土壤和阻止的驱散去去。另外,不去在表面上或在工厂的房间内被检测;这发现证实了那去不是 phytotoxic。因此,去可以用作有希望的无毒的添加剂增加工厂收益。 | Yijia He Ruirui Hu Yujia Zhong Xuanliang Zhao Qiao Chen Hongwei Zhu | 2018 | Nano Research2018，11，4： | 20 |
| 2 | In situ decomposition of metal-organic frameworks into ultrathin nanosheets for the oxygen evolution reaction显示文摘氧进化反应(OER ) 是一个枢轴的过程为切开水并且包含氧电极的许多另外的精力技术。此处,新合成策略被建议准备 OER 催化剂基于一简单在共同基于的醋酸盐氢氧化物的 situ 分解还灵活金属器官的框架(MOF ) 。这个过程与优秀部件可控制性允许各种各样的 2D 氢氧化物 ultrathin nanosheets (UNS ) 的直接制造。同样获得的共同基于的氢氧化物 UNS 由于众多的活跃地点的暴露为 OER 表明优异催化活动。特别地, CoNi 氢氧化物 UNS 展出低过电位() 在 10 和 100 妈的当前的密度的 324 和 372 mV ? 沬? | Kai He Zhen Cao Ruirui Liu Ya Miao Yi Ding | 2016 | Nano Research2016，9，6： | 7 |
| 3 | Graphene oxide as an antimicrobial agent can extenCthe vase life of cut flowers显示文摘"PlantNanOmics" is an emerging topic in agricultural research that explores thepotential effect of application of nanomaterials on plant growth. Graphene oxide(GO) has excellent properties due to its basal carbon plane and oxygen-containingfunctional groups. In the present work, the antimicrobial activity of GO wasexploited to extend the vase life and improve the quality of cut roses (cv. Carola).The results revealed that the cut roses cultivated in low doses of GO (0.1 mg/L)had longer vase life, larger diameter, and better water relations. Microbialcontaminations at the basal stem end is the most common reason for stemblockage that causes water stress and early wilting of cut flowers. GO wasfound to act as a germicide, effectively inhibiting the microbial growth atthe cut stem end and improving water uptake and water balance of cut roses.Therefore, GO can serve as a promising preservative to increase the ornamentalvalue of cut flowers. | Yijia He Lichao Qian Xu Liu Ruirui Hu Meirong Huang Yule Liu Guoqiang Chen Dusan Losic Hongwei Zhu | 2018 | Nano Research2018，11，11： | 6 |
| 4 | CitGVD:a comprehensive database of citrus genomic variations显示文摘Citrus is one of the most important commercial fruit crops worldwide.With the vast genomic data currently available for citrus fruit,genetic relationships,and molecular markers can be assessed for the development of molecular breeding and genomic selection strategies.In this study,to permit the ease of access to these data,a web-based database,the citrus genomic variation database(CitGVD,http://gffzz1758061741e3440chw0wkvfo00pxq6q65.ffgz.tsg.suse.edu.cn/home)was developed as the first citrusspecific comprehensive database dedicated to genome-wide variations including single nucleotide polymorphisms(SNPs)and insertions/deletions(INDELs).The current version(V1.0.0)of CitGVD is an open-access resource centered on 1,493,258,964 high-quality genomic variations and 84 phenotypes of 346 organisms curated from in-house projects and public resources.CitGVD integrates closely related information on genomic variation annotations,related gene annotations,and details regarding the organisms,incorporating a variety of built-in tools for data accession and analysis.As an example,CitGWAS can be used for genome-wide association studies(GWASs)with SNPs and phenotypic data,while CitEVOL can be used for genetic structure analysis.These features make CitGVD a comprehensive web portal and bioinformatics platform for citrus-related studies.It also provides a model for analyzing genome-wide variations for a wide range of crop varieties. | Qiang Li Jingjing Qi Xiujuan Qin Wanfu Dou Tiangang Lei Anhua Hu Ruirui Jia Guojin Jiang Xiuping Zou Qin Long Lanzhen Xu Aihong Peng Lixiao Yao Shanchun Chen Yongrui He | 2020 | Horticulture Research2020，7，1： | 4 |
| 5 | MicroRNA Expression Signature and Antisense-Mediated Depletion Reveal an Essential Role of MicroRNA in Vascular Neointimal Lesion Formation显示文摘 | Ruirui Ji Yunhui Cheng Junming Yue Jian Yang Xiaojun Liu He Chen David B. Dean Chunxiang Zhang | 2007 | Circulation Research2007，，11： | 4 |
| 6 | Cloning and Expression Analysis of Citrus Genes Cs GH3.1 and Cs GH3.6Responding to Xanthomonas axonopodis pv. citri Infection显示文摘To study the functions of the early auxin-responsive genes Cs GH3.1 and Cs GH3.6 in citrus resistance against canker disease, we cloned Cs GH3.1and Cs GH3.6 in ‘Newhall' Navel Orange(Citrus sinensis Osbeck). They are 1 797 bp and 1 887 bp and encode 598 and 629 amino acids, respectively. In vitro mature leaves from susceptible ‘Newhall' and resistant Calamondin(C. madurensis) were inoculated by a Xanthomonas axonopodis pv. citri(Xac) bacterial suspension, and expression of Cs GH3.1 and Cs GH3.6 in the two varieties were analyzed using quantitative real-time PCR(q RT-PCR). ‘Newhall' leaves were treated with different hormones for 3 days, inoculated by Xac bacterial suspension, and then the symptoms in these leaves were investigated. We used q RT-PCR to analyze the effect of different hormones on Cs GH3.1 and Cs GH3.6 expression in ‘Newhall'leaves. The expression levels of both Cs GH3.1 and Cs GH3.6 were significantly induced by Xac in ‘Newhall' leaves, compared with levels in Calamondin leaves. 1-naphthy acetic acid(NAA) increased the hypertrophy of infection sites in ‘Newhall' leaves, while naphthyl-phthalamic acid(NPA)had no visible effect on lesion development. NAA hormone greatly improved expression of Cs GH3.1 in ‘Newhall', but not Cs GH3.6. These results indicate that the auxin primary-response gene Cs GH3.1 plays an important role in citrus susceptibility to Xac. | CHEN Min HE Yongrui XU Lanzhen PENG Aihong LEI Tiangang YAO Lixiao LI Qiang ZHOU Pengfei BAI Xiaojing DUAN Minjie JIANG Xueyou JIA Ruirui ZOU Xiuping CHEN Shanchun | 2016 | Horticultural Plant Journal2016，2，4： | 4 |
| 7 | Effect of Gubi prescription on caveolin-1 expression and phosphoinositide 3 kinase/protein kinase B and Fas signal pathways in rats with knee osteoarthritis显示文摘OBJECTIVE: To investigate the effects of Gubi prescription on the expression of caveolin-1, and the phosphoinositide 3 kinase/protein kinase B(PI3 K/Akt) and Fas signal pathways in rats with knee osteoarthritis(KOA).METHODS: Forty KOA model rats were established using a modification of Hulth's method. Rats were divided into five groups by the random number method: model, positive drug(Vicolli group), and high-, medium-, and low-dose Gubi prescription groups(n = 8/group). In the sham surgery group(n = 8), only anterior and posterior cruciate ligaments of rats were exposed during surgery. A normal group(n = 8) consisted of rats with no treatment. Rats were intragastrically administered corresponding drugs once every day for eight consecutive weeks. Then, rat synovial membranes were extracted and histomorphological changes were recorded. m RNA expression was measured by q-PCR.Serum superoxide dismutase(SOD), malondialdehyde(MDA), nitric oxide(NO), and interleukin 1β(IL-1β) levels were measured. Western blotting determined the effects of Gubi prescription on protein expressions of caveolin-1, Bax, Bcl-2, Fas, and caspase-3 in chondrocytes from KOA rats. The knee cartilage of rats was excised and cultured under aseptic conditions. After coincubation of chondrocytes with Gubi prescription-containing serum, IL-1β, and si RNA, Western blotting was used to determine the protein expressions of caveolin-1, Bax, Bcl-2, Fas, and caspase-3.RESULTS: The morphological score of the articular synovium in the model group was significantly higher than in the normal group(P < 0.01). The morphological score in the high-and mediumdose Gubi prescription groups was lower than in the model group(P < 0.05). Chondrocytes from the decoction-containing serum group had a lower expression of Bax(P < 0.05), and higher expressions of Bcl-2(P < 0.05) and caspase-3(P < 0.05) compared with the model group. Chondrocytes in the decoction-containing serum group had higher expressions of Bax and Bcl-2(P < 0.01) and lower expressions of caveolin-1 and Fas(P < 0.05) compared with the model group. Compared with the model group, Bax and caspase-3 expressions were reduced in the chondrocytes of all three Gubi prescription groups(P < 0.05) whereas Bcl-2 expression was increased(P < 0.05). Compared with the model group, the expressions of caveolin-1 and Fas(P < 0.05) were reduced in groups that received high-and medium-doses of Gubi prescription. Gubi prescription increased the serum level of SOD and significantly reduced those of MDA, NO and IL-1β(P < 0.05).CONCLUSION: Gubi prescription suppressed the chondrocyte-related PI3 K/Akt and Fas signal pathways and inhibited the overexpression of caveolin-1 in rat chondrocytes. | He Xiaojin Wang Lei Zhou Xueping Xu Luzhou Cao Jing Wang Ruirui Wang Min Xie Guoqian | 2020 | Journal of Traditional Chinese Medicine2020，40，2： | 3 |
| 8 | Secondary donor-derived CD19 CAR-T therapy is safe and efficacious in acute lymphoblastic leukemia with extramedullary relapse after first autologous CAR-T therapy显示文摘Despite the advancement of treatments,adults with relapsed/refractory(R/R)B-lineage acute lymphoblastic leukemia(B-ALL)have poor prognosis,with an expected five-year overall survival(OS)rate of 10%‒20%(Nguyen et al.,2008;Oriol et al.,2010).Extramedullary relapse of B-ALL is regarded as a highrisk factor generally associated with poor survival,occurring in about 15%to 20%of all relapsed patients(Ding et al.,2017;Sun et al.,2018).The central nervous system(CNS)and the testes are the most common sites of extramedullary relapse of B-ALL.In addition,extramedullary leukemia can appear in the skin,eyes,breasts,bones,muscles,and abdominal organs.The prognosis of relapsed extramedullary B-ALL after allogeneic hematopoietic stem cell transplantation(allo-HSCT)is extremely poor(Spyridonidis et al.,2012;Dahlberg et al.,2019).Conventional chemotherapy or radiation is often ineffective in such patients.At present,there are no optimal treatment strategies for treating extramedullary leukemia after allo-HSCT. | Delin KONG Tingting YANG Jia GENG Ruirui JING Qiqi ZHANG GuoqingWEI He HUANG Yongxian HU | 2022 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2022，23，10： | 2 |
| 9 | Stability,acidity and interaction properties of [Bmim][SbF_6] coupled with concentrated sulfuric acid显示文摘Ionic liquid coupled with strong acid systems presents considerable promise in some catalytic fields.In the present work,the multiple complex systems composed by 98 wt%concentrated sulfuric acid and[Bmim][SbF_6]were investigated in the terms of stability,acidity and interaction properties.It was found that acidolysis of[Bmim][SbF_6]occurred in the 98 wt%concentrated sulfuric acid accompanied by HF releasing and SbF_6~ degrading to[SbF_(6-y)XHSO_4]_y]^-.The species after acidolysis in the multiple complex systems were checked and confirmed by electrospray ionization mass spectrometry(ESI-MS),Fourier transform infrared spectroscopy(FT-IR),~1H NMR and ^(19)F NMR.Acidity increased slightly with less than 1 wt%[Bmim][SbF_6]addition,while decreased with more proportion,which was determined based on the Hammett acidity functions H_0,using ^(13)C NMR.The strong hydrogen bond S-O-H…F of interaction among the multiple complex systems was confirmed by molecular dynamic simulation. | Honghua Zhang Ruixia Liu Ruirui Zhang Feng Huo Zhiqiang Yang Bin He Suojiang Zhang Yanji Wang | 2017 | Science China Chemistry2017，60，9： | 2 |
| 10 | The C_(6)D_(6)detector system on the Back-n beam line of CSNS显示文摘Introduction The neutron capture cross sections are very important in the field of nuclear device design and basic physics research.Hydrogen-free liquid scintillator such as C_(6)D_(6)detectors are widely used in the neutron capture cross-sectional measurements for the low neutron sensitivity and fast time response.The Back-n white neutron source at China Spallation Neutron Source is the first spallation white neutron source in China,and it is suitable for neutron capture cross-sectional measurement.Materials and methods A C_(6)D_(6)detector system was built in the Back-n experimental station.The pulse height weighting technique was used to determine the system’s detection efficiency.The response to gamma rays of the C_(6)D_(6)detector was measured,and the energy resolution function was determined.Monte Carlo simulation with Geant4 code was carried out to get the weighting function of this C_(6)D_(6)detector system.Additionally,the systematic uncertainty of the weighting function was also determined.Conclusion According to the experimental and simulation results,this C_(6)D_(6)detector system can be used to measure neutron capture cross section. | Jie Ren Xichao Ruan Jie Bao Guangyuan Luan Wei Jiang Qi An Huaiyong Bai Ping Cao Qiping Chen Yonghao Chen Pinjing Cheng Zengqi Cui Ruirui Fan Changqing Feng Minhao Gu Fengqin Guo Changcai Han Zijie Han Guozhu He Yongcheng He Yuefeng He Hanxiong Huang Weiling Huang Xiru Huang Xiaolu Ji Xuyang Ji Haoyu Jiang Hantao Jing Ling Kang Mingtao Kang Bo Li Lun Li Qiang Li Xiao Li Yang Li Yang Li Rong Liu Shubin Liu Xingyan Liu Yinglin Ma Changjun Ning Binbin Qi Zhaohui Song Hong Sun Xiaoyang Sun Zhijia Sun Zhixin Tan Hongqing Tang Jingyu Tang Pengcheng Wang Qi Wang Taofeng Wang Yanfeng Wang Zhaohui Wang Zheng Wang Jie Wen Zhongwei Wen Qingbiao Wu Xiaoguang Wu Xuan Wu Likun Xie Yiwei Yang Han Yi Li Yu Tao Yu Yongji Yu Guohui Zhang Jing Zhang Linhao Zhang Liying Zhang Qingmin Zhang Qiwei Zhang Xianpeng Zhang Yuliang Zhang Zhiyong Zhang Yingtan Zhao Liang Zhou Zuying Zhou Danyang Zhu Kejun Zhu Peng Zhu | 2019 | Radiation Detection Technology and Methods2019，3，3： | 1 |
| 11 | Review on fiber morphology obtained by bubble electrospinning and blown bubble spinning显示文摘 | HE Jihuan KONG Haiyan YANG RuiRui | 2012 | Thermal Science2012，5，16： | 1 |
| 12 | Study on the fragmentation pathway of the aconitine-type alkaloids under alectrospray ionization tandem mass spectrometry utilizing quantum chemistry 显示文摘 | Chen Xin Tan Peng He Ruirui | 2013 | J Pharm Innov2013，8，2： | 1 |
| 13 | Bubble- electrospinning for fabricating nanofibers 显示文摘 | YANG Ruirui HE Jihuan LAN Xu | 2009 | Polymer2009，50，24： | 1 |
| 14 | MicroRNAs Are Aberrantly Expressed in Hypertrophic Heart显示文摘 | Yunhui Cheng Ruirui Ji Junming Yue Jian Yang Xiaojun Liu He Chen David B. Dean Chunxiang Zhang | 2007 | The American Journal of Pathology2007，，6： | 1 |
| 15 | DOCK2 regulates antifungal immunity by regulating RAC GTPase activity显示文摘Fungal infections cause~1.5 million deaths each year worldwide,and the mortality rate of disseminated candidiasis currently exceeds that of breast cancer and malaria.The major reasons for the high mortality of candidiasis are the limited number of antifungal drugs and the emergence of drug-resistant species.Therefore,a better understanding of antifungal host defense mechanisms is crucial for the development of effective preventive and therapeutic strategies.Here,we report that DOCK2(dedicator of cytokinesis 2)promotes indispensable antifungal innate immune signaling and proinflammatory gene expression in macrophages.DOCK2-deficient macrophages exhibit decreased RAC GTPase(Rac family small GTPase)activation and ROS(reactive oxygen species)production,which in turn attenuates the killing of intracellular fungi and the activation of downstream signaling pathways.Mechanistically,after fungal stimulation,activated SYK(spleen-associated tyrosine kinase)phosphorylates DOCK2 at tyrosine 985 and 1405,which promotes the recruitment and activation of RAC GTPases and then increases ROS production and downstream signaling activation.Importantly,nanoparticle-mediated delivery of in vitro transcribed(IVT)Rac1 mRNA promotes the activity of Rac1 and helps to eliminate fungal infection in vivo.Taken together,this study not only identifies a critical role of DOCK2 in antifungal immunity via regulation of RAC GTPase activity but also provides proof of concept for the treatment of invasive fungal infections by using IVT mRNA. | Xiaojian Ma Xi Tan Bingbing Yu Wanwei Sun Heping Wang Huijun Hu Yanyun Du Ruirui He Ru Gao Qianwen Peng Zhihui Cui Ting Pan Xiong Feng Junhan Wang Chengqi Xu Bin Zhu Wei Liu Chenhui Wang | 2022 | Cellular & Molecular Immunology2022，19，5： | 1 |
| 16 | Bubble-eleetro- spinning for fabricating nanofibers 显示文摘 | Yang Ruirui He Jihuan Xu Lan el al | 2009 | Polymer2009，50，24： | 1 |
| 17 | MicroRNA Expression Signature and Antisense-Mediated Depletion Reveal an Essential Role of MicroRNA in Vascular Neointimal Lesion Formation显示文摘 | Ruirui Ji Yunhui Cheng Junming Yue Jian Yang Xiaojun Liu He Chen David B. Dean Chunxiang Zhang | 2007 | Circulation Research2007，，11： | 1 |
| 18 | Detector development at the Back-n white neutron source显示文摘Purpose Back-n is a white neutron beamline at China spallation neutron source,which was established in the year of 2018.It is a powerful facility for nuclear data measurement,neutron detector calibration,and radiation effect research.Method A series of detectors were built for different experiments,including beam monitoring,beam profile measurement,neutron induced secondaries(fission fragments,light charged particles and gamma)cross section measurement,and neutron resonance radiography,etc.A common digitization electronics and a cluster-based DAQ were developed for these detector systems.Most detectors have been employed at Back-n and serviced for experiments from the beginning of the beamline running.Results and conclusion As an overview of detectors of Back-n,the details of the detector design and the experiment performing are described in this paper.Some developing systems,e.g.,MTPC and B-MCP,are also included. | Fan Ruirui Li Qiang Bao Jie Li Yang Liu Rong Jiang Wei Ren Jie Zhang Qiwei Cao Ping Gu Minhao Ren Zhizhou Yi Han Tang Jingyu An Qi Bai Haofan Bai Jiangbo Chen Qiping Chen Yonghao Chen Zhen Cui Zengqi Fan Anchuan Feng Changqing Feng Fanzhen Gao Keqing Han Changcai Han Zijie He Guozhu He Yongcheng Hong Yang Hu Yiwei Huang Hanxiong Jia Weihua Jiang Haoyu Jiang Zhijie Jin Zhengyao Kang Ling Li Bo Li Chao Li Gong Li Jiawen Li Xiao Liu Jie Liu Shubin Luan Guangyuan Ning Changjun Qi Binbin Ruan Xichao Song Zhaohui Sun Kang Tan Zhixin Tang Shengda Wang Pengcheng Wang Zhaohui Wen Zhongwei Wu Xiaoguang Wu Xuan Xie Likun Yang Yiwei Yu Yongji Zhang Guohui Zhang Linhao Zhang Mohan Zhang Xianpeng Zhang Yuliang Zhang Yue Zhang Zhiyong Zhao Maoyuan Zhou Luping Zhou Zhihao Zhu Kejun The CSNS Back-n Collaboration | 2023 | Radiation Detection Technology and Methods2023，7，2： | 0 |
| 19 | Epstein-Barr virus infection:the leading cause of multiple sclerosis显示文摘In a recent study published in Science,Bjornevik and colleagues demonstrated Epstein-Barr virus(EBV)infection is a trigger for multiple sclerosis(MS)in a longitudinal analysis of more than 10 million US military individuals who were on active duty.1 MS is an autoimmune disease that originates in the central nervous system characterized by inflammatory demyelinating lesions.There is no consensus on the etiology of MS.However,we all know that MS is a multifactorial disease which can be influenced by genetic and environmental factors.Genetic factors associated with MS risk are mainly major histocompatibility class Ⅱ(MHC Ⅱ)alleles(e.g.,HLA-DRB1^(*)15:01,the earliest identified and most dominant risk factor in MS)and MHC I alleles(e.g.,HLA-A^(*)02 and HLA B^(*)44,decreasing MS susceptibility). | Ruirui He Yanyun Du Chenhui Wang | 2022 | Signal Transduction and Targeted Therapy2022，7，8： | 0 |
| 20 | Ultrathin nanoporous metal-semiconductor heterojunction photoanodes for visible light hydrogen evolution显示文摘Plasmonic 金属半导体 nano 异质接面(NHJ ) 与他们的优异 photocatalytic 表演,为太阳能的有效利用提供机会。然而,科学意义和技术挑战为新产生留在合适的金属半导体 NHJ photoelectrodes 的发展灵活 optoelectronic 设备,它经常要求复杂处理。此处,我们报导综合三维(3D ) NHJ photoelectrodes 由保角地,涂层镉硫化物(CdS ) nanolayers 经由一个灵巧的电极淀积方法拍摄到 ultrathin nanoporous 黄金(NPG ) 上。NPG 的局部性的表面电浆子回声(LSPR ) 提高电子洞对产生和分离。而且,直接接触接口和 NHJ 的高传导性的框架结构增加 photogenerated 搬运人分离和运输。因此, NHJ 展览显然相对在任何一个黄金(Au ) 上扔的 CdS 提高了光电流密度和氢进化率在在可见光的照耀下面的 0 V 对 SCE (浸透的甘汞电极) 的陪衬或做氟的符号的锡氧化物(FTO ) 。而且,他们表明令人惊讶地稳定的 photoelectrochemical 氢进化(PEC -- 他) 在连续照耀的 104 s 上的活动。 | Weiqing Zhang Yunfeng Zhao Kai He Jun Luo Guoliang Li Ruirui Liu Siyu Liu Zhen Cao Pengtao Jing Yi Ding | 2018 | Nano Research2018，11，4： | 0 |
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