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| 1 | 缺血性卒中的一级预防——美国心脏协会/美国卒中协会卒中委员会指南 动脉粥样硬化性周围血管病跨学科工作组、心血管护理委员会、临床心脏病学委员会、营养、体力活动和代谢委员会以及医疗质量和转归研究跨学科工作组共同倡导显示文摘背景和目的本指南提供有关各种确定和潜在的卒中危险因素证据的概述,并提供降低卒中风险的推荐。方法写作组成员由委员会主席根据每位作者先前在相关课题领域中的工作提名,并经美国心脏协会(AHA)卒中委员会科学声明监督委员会批准。写作组采用系统文献回顾(涵盖时间段为2001年最后一次回顾发表到2005年1月),参考先前已发表的指南、个人文件和专家意见来概括现有的证据,指明现有知识的差距;如果合适,则根据标准的AHA标准做出简明的推荐。写作组全体成员在撰写过程中均有很多机会对推荐进行评论并认可这份声明的最终版本。在AHA科学咨询与协调委员会批准之前,本指南已进行过广泛的同行评议。结果对评价个体首次卒中风险的流程图进行评估。根据干预的可能性(不可干预、可干预或潜在可干预)和证据的强度(证据充分或证据不太充分),对首次卒中的危险因素或风险标记物进行分类。不可干预的危险因素包括年龄、性别、出生体重低、人种/种族和遗传因素。证据充分的可干预危险因素包括高血压、主动或被动吸烟、糖尿病、心房颤动和某些其他心脏病、血脂异常、颈动脉狭窄、镰状细胞病、绝经后激素治疗、不良饮食习惯、缺乏体力活动、肥胖和体脂分布。证据不太充分或潜在的可干预危险因素包括代谢综合征、酗酒、药物滥用、口服避孕药、睡眠呼吸障碍、偏头痛、高同型半胱氨酸血症、脂蛋白(a)升高、脂蛋白相关的磷脂酶升高、高凝状态、炎症和感染。对应用阿司匹林进行卒中一级预防的资料进行回顾。结论有大量证据可以用于确定增加首次卒中风险的各种特殊因素和提供降低这种风险的策略。 | Larry B. Goldstein Robert Adams Mark J. Alberts Lawrence J. Appel Lawrence M. Brass Cheryl D. Bushnell Antonio Culebras Thomas J. DeGraba Philip B. Gorelick John R. Guyton Robert G. Hart George Howard Margaret Kelly-Hayes J.V. (Ian) Nixon Ralph L. Sacco 苏克江 高宗恩 | 2006 | 国际脑血管病杂志2006，14，8： | 28 |
| 2 | DEVELOPMENT OF COMMON WHEAT GERM-PLASM RESISTANT TO BARLEY YELLOW DWARF VIRUS BY BIOTECHNOLOGY显示文摘Barley yellow dwarf virus (BYDV) is one of the most serious wheat diseases in China. So far no resistance has been described in common wheat. A certain level of BYDV resistance was found in thirteen Triticeae species. Thinopyrum intermedium, two octoploids derived from TH. intermedium/wheat, Zhong 4 awnless and TAF46, and one disomic addition line, L1 derived from TAF46, showed good resistance to BYDV by enzyme linked immunosorbent assay (ELISA). Two wheat/TA. intermedium translocation lines, CPI 119880 and CPI 119899, showing good BYDV resistance were developed from L1 by using both CSph mutant and tissue culture. It is found that their BYDV resistance was controlled by a single dominant gene. Two cDNA probes pEleAcc3 and pPJN8 (E1-T1) were screened for detecting Th. intermedium DNA in wheat background. A specific band for the DNA of Th. intermedium and its derivatives was found in Southern hybridization. It is also possible to determine the size of the alien segment by comparing the relative density | 辛志勇 徐惠君 陈孝 林志珊 周广和 钱幼亭 成卓敏 P. J. LARKIN P. BANKS R. APPELS B. GLARKE AND R. I. S. BRETTELL | 1991 | Science China Chemistry1991，34，9： | 13 |
| 3 | 卒中一级预防指南 美国心脏协会/美国卒中协会为医疗卫生专业人员制定的指南美国神经病学学会肯定本指南作为神经科医生继续教育工具的价值显示文摘背景和目的本指南对各种已确定和新出现的卒中危险因素的证据进行概述,以提供降低首次卒中风险的循证推荐。方法写作组成员由委员会主席根据每位成员先前在相关课题领域中的工作提名,并经美国心脏协会(American HeartAssociation,AHA)卒中委员会科学声明监督委员会批准。写作组采用系统文献回顾的方法(涵盖时间为2006年上一次回顾发表到2009年4月),参考先前已发表的指南、个人文件和专家意见来总结现有证据,并指出现有知识的差距;如果合适,则根据标准的AHA标准做出推荐。写作组全体成员均有机会对推荐进行评论并审核这份声明的最终文本。在AHA科学咨询和协调委员会考察和批准之前,本指南已南卒中委员会领导层和AIIA科学声明督察委员会进行过广泛的同行评议。结果对评价个体首次卒巾风险的流程图进行了评价。根据干预的町能性(不可于预、可于预或潜在可干预)和证据的强度(证据充分或证据不太充分),对首次卒中的危险因素或风险标记物进行分类。不可干预危险因素包括年龄、性别、低出生体质量、人种/种族和遗传倾向。证据充分的叮干预危险因素包括高血压、吸烟、糖尿病、心房颤动和某些其他心脏病、血脂异常、颈动脉狭窄、镰状细胞病、绝经后激素治疗、不良饮食习惯、体力活动过少以及肥胖和体脂分布。证据不太充分或潜在的可干预危险因素包括代谢综合征、酗酒、药物滥用、口服避孕药、睡眠呼吸障碍、偏头痛、高同型半胱氨酸血症、脂蛋白(a)升高、高凝状态、炎症和感染。对用阿司匹林进行卒中一级预防的资料进行了回顾。结论多方面的证据可用于确定能增高首次卒中风险的多种具体因素并提供降低这种风险的策略。 | Larry B. Goldstein Cheryl D. Bushnell Robert J. Adams Lawrence J. Appel Lynne T. Braun Seemant Chaturvedi Mark A. Creager Antonio Culebras Robert H. Eckel Robert G. Hart Judith A. Hinchey Virginia J. Howard Edward C. Jauch Steven R. Levine James F. Meschia Wesley S. Moore J.V. (Ian) Nixon Thomas A. Pearson 张霞(译) 尤寿江(译) 陈孝东(译) 卢涛声(译) 石际俊(译) 曹勇军(译) 徐兴顺(译) | 2010 | 国际脑血管病杂志2010，18，12： | 12 |
| 4 | Guidelines for the Primary Prevention of Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association显示文摘 | Larry B. Goldstein Cheryl D. Bushnell Robert J. Adams Lawrence J. Appel Lynne T. Braun Seemant Chaturvedi Mark A. Creager Antonio Culebras Robert H. Eckel Robert G. Hart Judith A. Hinchey Virginia J. Howard Edward C. Jauch Steven R. Levine James F. Meschi | 2011 | Stroke2011，，2： | 6 |
| 5 | Mechanisms of lead, copper, and zinc retention by phosphate rock显示文摘 | Xinde Cao Lena Q. Ma Dean R. Rhue Chip S. Appel | 2004 | Environmental Pollution2004，，3： | 4 |
| 6 | Mechanisms of lead, copper, and zinc retention by phosphate rock显示文摘 | Xinde Cao Lena Q. Ma Dean R. Rhue Chip S. Appel | 2004 | Environmental Pollution2004，，3： | 2 |
| 7 | Genes active in developing wheat endosperm显示文摘 | B.C. Clarke M. Hobbs D. Skylas R. Appels | 2000 | Functional & Integrative Genomics2000，，1： | 1 |
| 8 | Allelic variants of phytoene synthase 1 (Psy1) genes in Chinese and CIMMYT wheat cultivars and development of functional markers for flour colour显示文摘 | X. Y. He Z. H. He W. Ma R. Appels X. C. Xia | 2009 | Molecular Breeding2009，，4： | 1 |
| 9 | Allelic variants of phytoene synthase 1 (Psy1) genes in Chinese and CIMMYT wheat cultivars and development of functional markers for flour colour显示文摘 | X. Y. He Z. H. He W. Ma R. Appels X. C. Xia | 2009 | Molecular Breeding2009，，4： | 1 |
| 10 | Microstructural evolution during hot working of ti aluminide alloys: Influence of phase constitution and initial casting texture显示文摘 | R. M. Imayev V. M. Imayev M. Oehring F. Appel | 1996 | Metallurgical and Materials Transactions A1996，，13： | 1 |
| 11 | The 5S DNA units of bread wheat ( Triticum aestivum )显示文摘 | R. Appels B. R. Baum B. C. Clarke | 1992 | Plant Systematics and Evolution1992，，3： | 1 |
| 12 | Branched chain amino acids are novel biomarkers for discrimination of metabolic wellness显示文摘 | Bryan C. Batch Svati H. Shah Christopher B. Newgard Christy B. Turer Carol Haynes James R. Bain Michael Muehlbauer Mahesh J. Patel Robert D. Stevens Lawrence J. Appel L. Kristin Newby Laura P. Svetkey | 2013 | Metabolism2013，，7： | 1 |
| 13 | Fine scale genetic and physical mapping using interstitial deletion mutants of Lr34 /Yr18: a disease resistance locus effective against multiple pathogens in wheat显示文摘 | W. Spielmeyer R. P. Singh H. McFadden C. R. Wellings J. Huerta-Espino X. Kong R. Appels E. S. Lagudah | 2008 | Theoretical and Applied Genetics2008，，4： | 1 |
| 14 | The low-molecular-weight glutenin subunit proteins of primitive wheats. IV. Functional properties of products from individual genes显示文摘 | Y.-K. Lee F. Bekes P. Gras M. Ciaffi M. K. Morell R. Appels | 1999 | TAG Theoretical and Applied Genetics1999，，1： | 1 |
| 15 | Beyond Medications and Diet: Alternative Approaches to Lowering Blood Pressure: A Scientific Statement From the American Heart Association显示文摘 | Robert D. Brook Lawrence J. Appel Melvyn Rubenfire Gbenga Ogedegbe John D. Bisognano William J. Elliott Flavio D. Fuchs Joel W. Hughes Daniel T. Lackland Beth A. Staffileno Raymond R. Townsend Sanjay Rajagopalan | 2013 | Hypertension2013，，6： | 1 |
| 16 | Sensitivity of the Community Multiscale Air Quality (CMAQ) model v4.7 results for the eastern United States to MM5 and WRF meteorological drivers显示文摘 | Appel K. W. Roselle S. J. Gilliam R. C. Pleim J. E | 2010 | Geoscientific Model Development2010，，4： | 1 |
| 17 | Meta-Analysis of Folic Acid Supplementation Trials on Risk of Cardiovascular Disease and Risk Interaction With Baseline Homocysteine Levels显示文摘 | Edgar R. Miller Stephen Juraschek Roberto Pastor-Barriuso Lydia A. Bazzano Lawrence J. Appel Eliseo Guallar | 2010 | The American Journal of Cardiology2010，，4： | 1 |
| 18 | M?gliche Komplikationen bei der arthroskopischen Lavage des Kiefergelenks显示文摘 | S. Bergé J.-J. von Lindern B. Niederhagen T. Appel R. H. Reich | 2001 | Mund - Kiefer - und Gesichtschirurgie2001，，4： | 1 |
| 19 | Variation at the Nor loci in triticale derived from tissue culture显示文摘 | R. I. S. Brettell M. A. Pallotta J. P. Gustafson R. Appels | 1986 | Theoretical and Applied Genetics1986，，4： | 1 |
| 20 | A Novel STS Marker for Polyphenol Oxidase Activity in Bread Wheat显示文摘 | D. J. Sun Z. H. He X. C. Xia L. P. Zhang C. F. Morris R. Appels W. J. Ma H. Wang | 2005 | Molecular Breeding2005，，3： | 1 |
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