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36篇 您的检索式:作者名="Polydorides"
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1High-resolution microendoscopy for esophageal cancer screening in China: A cost-effectiveness analysis显示文摘AIM:To study the cost-effectiveness of high-resolution microendoscopy(HRME)in an esophageal squamous cell carcinoma(ESCC)screening program in China.METHODS:A decision analytic Markov model of ESCC was developed.Separate model analyses were conducted for cohorts consisting of an averagerisk population or a high-risk population in China.Hypothetical 50-year-old individuals were followed until age 80 or death.We compared three different strategies for both cohorts:(1)no screening;(2)standard endoscopic screening with Lugol’s iodine staining;and(3)endoscopic screening with Lugol’s iodine staining and an HRME.Model parameters were estimated from the literature as well as from GLOBOCAN,the Cancer Incidence and Mortality Worldwide cancer database.Health states in the model included non-neoplasia,mild dysplasia,moderate dysplasia,high-grade dysplasia,intramucosal carcinoma,operable cancer,inoperable cancer,and death.Separate ESCC incidence transition rates were generated for the average-risk and high-risk populations.Costs in Chinese currency were converted to international dollars(I$)and were adjusted to 2012dollars using the Consumer Price Index.RESULTS:The main outcome measurements for this study were quality-adjusted life years(QALYs)and incremental cost-effectiveness ratio(ICER).For the average-risk population,the HRME screening strategy produced 0.043 more QALYs than the no screening strategy at an additional cost of I$646,resulting in an ICER of I$11808 per QALY gained.Standard endoscopic screening was weakly dominated.Among the high-risk population,when the HRME screening strategy was compared with the standard screening strategy,the ICER was I$8173 per QALY.For both the high-risk and average-risk screening populations,the HRME screening strategy appeared to be the most cost-effective strategy,producing ICERs below the willingness-topay threshold,I$23500 per QALY.One-way sensitivity analysis showed that,for the average-risk population,higher specificity of Lugol’s iodine(>40%)and lower specificity of HRME(<70%)could make Lugol’s iodine screening cost-effective.For the high-risk population,the results of the model were not substantially affected by varying the follow-up rate after Lugol’s iodine screening,Lugol’s iodine test characteristics(sensitivity and specificity),or HRME specificity.CONCLUSION:The incorporation of HRME into an ESCC screening program could be cost-effective in China.Larger studies of HRME performance are needed to confirm these findings.Chin Hur Sung Eun Choi Chung Yin Kong Gui-Qi Wang Hong Xu Alexandros D Polydorides Li-Yan Xue Katherine E Perzan Angela C Tramontano Rebecca R Richards-Kortum Sharmila Anandasabapathy 2015World Journal of Gastroenterology2015,21,18:8
2Colorectal Dysplasia in Chronic Inflammatory Bowel Disease: Pathology, Clinical Implications, and Pathogenesis显示文摘Harpaz Noam Polydorides Alexandros D 2010Archives of Pathology & Laboratory Medicine2010,,6:3
3Precancerous lesions in inflammatory bowel disease显示文摘Noam Harpaz Stephen C. Ward Claudia Mescoli Steven H. Itzkowitz Alexandros D. Polydorides 2013Best Practice & Research Clinical Gastroenterology2013,,2:3
4嗜酸细胞性食管炎和食管颗粒细胞瘤:意想不到的关联(英)显示文摘食管颗粒细胞瘤(GCTs)非常罕见。嗜酸细胞性食管炎(EoE)是一种免疫介导疾病,以食管嗜酸性细胞浸润、质子泵抑制剂(PPI)疗法无效为特征。考虑到GCTs多发生于炎症反应及瘢痕形成部位,作者在GCTs住院患者中统计EoE发生率。搜集中心病理数据库1995-2014年间GCTs样本,并对其非典型细胞形态学特征评分。Riffle ME Polydorides AD Niakon J 曹琪(译) 张建中(校) 2017诊断病理学杂志2017,24,11:3
5The splice of life:alternative splicing and neurological disease显示文摘DREDGE B K POLYDORIDES A D DARNELL R B 2001Nat Rev Neurosci2001,2,1:1
6High resolution mi- croendoscopy for classification of colorectal polyps 显示文摘Chang SS Shukla R Polydorides AD 2013Endoscopy2013,45,7:1
7Accuracy and in- terrater reliability for the diagnosis of Barrett's neoplasia among users of a novel, portable high-resolution microendoscope 显示文摘Vila PM Kingsley MJ Polydorides AD 2014Dis Esophagus2014,27,1:1
8Discrimination of Benign and Neoplastic Mucosa with a High-Resolution Microendoscope (HRME) in Head and Neck Cancer显示文摘Peter Vila Chan Park Mark Pierce Gregg Goldstein Lauren Levy Vivek Gurudutt Alexandros Polydorides James Godbold Marita Teng Eric Genden Brett Miles Sharmila Anandasabapathy Ann Gillenwater Rebecca Richards-Kortum Andrew Sikora 2012Annals of Surgical Oncology2012,,:1
9Feasibility and preliminary accuracy of high-resolution imaging of the liver and pancreas using FNA compatible microendoscopy (with video)显示文摘Renu Regunathan Jenny Woo Mark C. Pierce Alexandros D. Polydorides Mohammad Raoufi Sasan Roayaie Myron Schwartz Daniel Labow Dongsuk Shin Rei Suzuki Manoop S. Bhutani Lezlee G. Coghlan Rebecca Richards-Kortum Sharmila Anandasabapathy Michelle Kang Kim 2012Gastrointestinal Endoscopy2012,,:1
10High resolution microendoscopy for classification of colorectal polyps显示文摘S. Chang R. Shukla A. Polydorides P. Vila M. Lee H. Han P. Kedia J. Lewis S. Gonzalez M. Kim N. Harpaz J. Godbold R. Richards-Kortum S. Anandasabapathy 2013Endoscopy2013,,:1
11Accuracy and interrater reliability for the diagnosis of B arrett’s neoplasia among users of a novel, portable high‐resolution microendoscope显示文摘P. M. Vila M. J. Kingsley A. D. Polydorides M.‐A. Protano M. C. Pierce J. Sauk M. K. Kim K. Patel J. H. Godbold J. D. Waye R. Richards‐Kortum S. Anandasabapathy 2014Dis Esophagus2014,,:1
12High res- olution microendoscopy for classification of colorcctal polyps 显示文摘CHANG S S SHUKLA R POLYDORIDES A D 2013Endoscopy2013,45,7:1
13High resolution microendoscopy for classification of colorectal polyps显示文摘S. Chang R. Shukla A. Polydorides P. Vila M. Lee H. Han P. Kedia J. Lewis S. Gonzalez M. Kim N. Harpaz J. Godbold R. Richards-Kortum S. Anandasabapathy 2013Endoscopy2013,,07:1
14Accu- racy and interrater reliability for the diagnosis of Barrett' s neoplasia among users of a novel, portable high-resolu- tion microendoscope 显示文摘Vila P M Kingsley M J Polydorides A D 2014Dis Esophagus2014,27,:1
15Accura- cy and interrater reliability for the diagnosis of Barrett's neopla- sia among users of a novel, portable high-resolution microendo- scope显示文摘VILA P M KINGSLEY M J POLYDORIDES A D 2014Diseases of the Esophagus2014,27,1:1
16Electrode configurations for improved spatial resolution in electrical impedance tomography 显示文摘Polydorid N McCann Hugh 2002Meas Sci Technol2002,,13:1
17Accu- racy and interrater reliability for the diagnosis of Barrettg neoplasia among users of a novel, portable high-resolu- tion microendoscope 显示文摘Vila P M Kingsley M J Polydorides A D 2014Dis Esophagus2014,27,2:1
18High resolution microendoscopy for classification of coloreetal polyps 显示文摘Chang S S Shuklal R Polydorides A D 2013Endoscopy2013,45,10:1
19Electrode configurations for improved spatial resolution in electrical impedance tomography 显示文摘Polydorides N McCann H 2002Meas Sci Technol2002,13,:1
20A Matlab toolkit for three-dimensional electrical impedance tomography:A contribution to the electrical impedance and diffuse optical reconstruction software project 显示文摘Polydorides N Lionheart W R B 2002Meas Sci Technol2002,13,:1
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