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21篇 您的检索式:作者名="Peter Sinclair"
    题名 作者 年代 出处 被引量
1Asymmetric synthesis of N-tertbutoxycarbonyl α-amino acids, Synthesis of ( 5S, 6R ) -4-tert-butoxycarbonyl-5,6-diphenylmorpholin-2-one 显示文摘 Peter Sinclair 2002Organic Syntheses2002,80,:1
2Hydatid infestation of brain: difficulties with computed tomography diagnosis and surgical treatment显示文摘Peter Jc Domingo Z Sinclair - Smith C 1994Pediatr Neurosurg1994,20,1:1
3Restricted expression of DMRT3 in chicken and mouse embryos显示文摘Craig A. Smith Tanya M. Hurley Peter J. McClive Andrew H. Sinclair 2003Mechanisms of Development2003,,:1
4Relationships between economic growth, foreign direct investment and trade: evidence from China显示文摘Xiaohui Liu Peter Burridge P. J. N. Sinclair 2002Applied Economics2002,,11:1
5Mobilising Community action towards a low-carbon future: Opportunities and Challenges for local government in the UK显示文摘PETERS M FUDGE S SINCLAIR P 2010Energy Policy2010,38,12:1
6A pilot study of the front foot ground reaction forces in elite female fast bowlers 显示文摘MAX C STUELCKEN PETER J SINCLAIR 2009J Sci Med Sport2009,12,2:1
7Mobilising Community Action towards a Low-Carbon Future:Opportunities and Challenges for Local Government in the UK显示文摘Peters M Fudge S Sinclair P 0,,12:1
8Bench-to-bedside review: Hy-pothermia in traumatic brain injury 显示文摘H Louise Sinclair Peter JD Andrews 2010Sinclair Andrews CriticalCare2010,14,1:1
9Predicting and preventing root resorption显示文摘Glenn T Sameshima Peter Sinclair 2001Am J Orthod Dentofacial Orthop2001,119,5:1
10Estimation of suspension of alkaline material by dust devils in the United States显示文摘Gillette Dale A Sinclair Peter C 1990Atmospheric Environment1990,24,5:1
11Predicting and preventing root resorption: Part I. Diagnostic factors显示文摘Glenn T. Sameshima Peter M. Sinclair 2001American Journal of Orthodontics & Dentofacial Orthopedics2001,,5:1
12Epidemiology and outcomes of acute liver failure in Australia显示文摘BACKGROUND Acute liver failure (ALF) is a life-threatening syndrome with varying aetiologies requiring complex care and multidisciplinary management. Its changing incidence, aetiology and outcomes over the last 16 years in the Australian context remain uncertain. AIM To describe the changing incidence, aetiology and outcomes of ALF in South Eastern Australia. METHODS The database of the Victorian Liver Transplant Unit was interrogated to identify all cases of ALF in adults (> 16 years) in adults hospitalised between January 2002 and December 2017. Overall, 169 patients meeting criteria for ALF were identified. Demographics, aetiology of ALF, rates of transplantation and outcomes were collected for all patients. Transplant free survival and overall survival (OS) were assessed based on survival to discharge from hospital. Results were compared to data from a historical cohort from the same unit from 1988- 2001. RESULTS Paracetamol was the most common aetiology of acute liver failure, accounting for 50% of cases, with an increased incidence compared with the historical cohort (P = 0.046). Viral hepatitis and non-paracetamol drug or toxin induced liver injury accounted for 15% and 10% of cases respectively. Transplant free survival (TFS) improved significantly compared to the historical cohort (52% vs 38%, P = 0.032). TFS was highest in paracetamol toxicity with spontaneous recovery in 72% of cases compared to 31% of non-paracetamol ALF (P < 0.001). Fifty-nine patients were waitlisted for emergency liver transplantation. Nine of these died while waiting for an organ to become available. Forty-two patients (25%) underwent emergency liver transplantation with a 1, 3 and 5 year survival of 81%, 78% and 72% respectively. CONCLUSION Paracetamol toxicity is the most common aetiology of ALF in South-Eastern Australia with a rising incidence over 30 years. TFS has improved, however it remains low in non-paracetamol ALF.Penelope Hey Timothy P Hanrahan Marie Sinclair Adam G Testro Peter W Angus Adam Peterson Stephen Warrillow Rinaldo Bellomo Marcos V Perini Graham Starkey Robert M Jones Michael Fink Tess McClure Paul Gow 2019World Journal of Hepatology2019,11,7:1
13Mobilising community action towards a low - carbon future: opportunities and challenges for local government in the UK 显示文摘Peters M Fudge S Sinclair P 2010Energy Policy2010,12,38:1
14The predictive value of total serum IgE for a positive allergen specific IgE result显示文摘SINCLAIR D PETERS S A 2004J Clin Pathol2004,57,:1
15SIRT1 mRNA Expression May Be Associated With Energy Expenditure and Insulin Sensitivity显示文摘Rutanen Jarno Yaluri Nagendra Modi Shalem Pihlajam?ki Jussi V?nttinen Markku Itkonen Paula Kainulainen Sakari Yamamoto Hiroyasu Lagouge Marie Sinclair David A Elliott Peter Westphal Christoph Auwerx Johan Laakso Markku 2010Diabetes2010,,4:1
16Mobilising Community Action towards a Low- Carbon Future:Opportunities and Challenges for Local Government in the UK 显示文摘Peters M Fudge S Sinclair P 2010Energy Policy2010,,12:1
17Aircraft low altitude wind shear detection and warning system显示文摘Peter C Sinclair M K Peter 1991J Appl Meteor1991,30,1:1
18EB病毒对伯基特淋巴瘤细胞系宿主基因表达的影响显示文摘背景与目的:Epstein-Barr病毒(Epstein-Barrvirus,EBV)以潜伏状态存在于Burkitt's淋巴瘤(Burkitt's lymphoma,BL)细胞中,其基因表达呈高度限制模式,只有少数肿瘤细胞存在病毒裂解性复制。BL细胞株可被诱导进入病毒裂解周期,通过刺激表面免疫球蛋白分子启动病毒复制过程。此过程中,有许多EBV基因表达,这些基因可能影响宿主基因的表达。本实验目的在于鉴定BL细胞中由EBV所调节的宿主基因及由表面IgG连接所调节的宿主基因。方法:利用微阵列检测EBV阳性Akata细胞和EBV阴性AK31细胞中差异性表达的基因。结果:Akata和AK31细胞中共有91个人类基因呈差异性表达,细胞受刺激进入裂解性复制后,检测到198个差异性表达基因。其中myd88基因的差异性表达与TLR9信号通路受损有关。结论:EBV下调了在裂解周期激活早期阶段由表面Ig交联作用所调节的大部分基因。这些基因与细胞存活、信号转导、转录控制以及可能调节B淋巴细胞和其他细胞(如可能影响病毒复制的HDAC4)EBV转化的免疫应答过程有关。Peter Broderick Michael Hubank Alison Sinclair 2009癌症2009,28,8:0
19Clinical outcomes of patients with two small hepatocellular carcinomas显示文摘BACKGROUND Management of single small hepatocellular carcinoma(HCC)is straightforward with curative outcomes achieved by locoregional therapy or resection.Liver transplantation is often considered for multiple small or single large HCC.Management of two small HCC whether presenting synchronously or sequentially is less clear.AIM To define the outcomes of patients presenting with two small HCC.METHODS Retrospective review of HCC databases from multiple institutions of patients with either two synchronous or sequential HCC≤3 cm between January 2000 and March 2018.Primary outcomes were overall survival(OS)and transplant-free survival(TFS).RESULTS 104 patients were identified(male n=89).Median age was 63 years(interquartile range 58-67.75)and the most common aetiology of liver disease was hepatitis C(40.4%).59(56.7%)had synchronous HCC and 45(43.3%)had sequential.36 patients died(34.6%)and 25 were transplanted(24.0%).1,3 and 5-year OS was 93.0%,66.1% and 62.3% and 5-year post-transplant survival was 95.8%.1,3 and 5-year TFS was 82.1%,45.85% and 37.8%.When synchronous and sequential groups were compared,OS(1,3 and 5 year synchronous 91.3%,63.8%,61.1%,sequential 95.3%,69.5%,64.6%,P=0.41)was similar but TFS was higher in the sequential group(1,3 and 5 year synchronous 68.5%,37.3% and 29.7%,sequential 93.2%,56.6%,48.5%,P=0.02)though this difference did not remain during multivariate analysis.CONCLUSION TFS in patients presenting with two HCC≤3 cm is poor regardless of the timing of the second tumor.All patients presenting with two small HCC should be considered for transplantation.Anh Duy Pham Karl Vaz Zaid S Ardalan Marie Sinclair Ross Apostolov Sarah Gardner Ammar Majeed Gauri Mishra Ning Mao Kam Kurvi Patwala Numan Kutaiba Niranjan Arachchi Sally Bell Anouk T Dev John S Lubel Amanda J Nicoll Siddharth Sood William Kemp Stuart K Roberts Michael Fink Adam G Testro Peter W Angus Paul J Gow 2021World Journal of Hepatology2021,13,10:0
20Trees as hotspots:Using forests,trees,and agroforestry to foster diverse sustainable landscapes显示文摘Forests,trees,and agroforestry(FTA)are ecosystem hotspots.They exemplify the contributions of biodiversity to sustainable and resilient landscapes,green circular economy and to sustainable agriculture and food systems for healthy diets.However,most research on these topics have been performed separately and lack comparison.The International FTA-Kunming Conference'Forests,trees and agroforestry for diverse sustainable landscapes'22nd–24th June 2021,focused on these contributions,brought together scientists NGOs,and policy makers to further the understanding of tree diversity;provided a communication platform for scientists to share their research results;evaluated the role of tree diversity in agroecology and circular agriculture;assessed benefits of landscape restoration;and explored applied research in mountain ecosystems and food security.The goals were to gather evidence that ground the design of solutions that can contribute to the implementation of the post 2020 Global Biodiversity Framework and towards the UN Food Systems Summit,and the overall implementation of the SDGs.This paper summarizes the outcomes of the international FTA Conference in Kunming 2021 and points out the highlights of research involved in six major themes.Vincent Gitz Jianchu Xu Yuanchang Lu Elaine Springgay Illias Animon Razan Khalifa Al Mubarak Robert Nasi Tony Simons Ranjit Barthakur Ren Wang Jianrong Su Fergus Sinclair Eduardo Somarriba Dossa G.O.Gbadamassi Ramni Jamnadass Christopher JKettle Dengpan Bu Anja Gassner Yves Laumonier Mi Zhou Himlal Baral Fangyuan Hua Peter AMinang Yufu Guo Michael Allen Brady Yanxia Li Peter Mortimer Bin Yang Heng Gui Fiona Worthy Deli Zhai Huafang Chen Huili Li Yufang Su Alexandre Meybeck Fabio Ricci 2022Circular Agricultural Systems2022,2,1:0
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