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| 1 | Efficacy of small-volume simethicone given at least 30 min before gastroscopy显示文摘AIM To evaluate the efficacy of 5 m L simethicone solution in decreasing gastric foam if given at least 30 min before gastroscopy.METHODS This was a randomized, placebo controlled, endoscopist blinded study performed at Changi General Hospital. Patients were at least 21 years old, had no prior sur-gical resection of the upper gastrointestinal tract, and scheduled for elective diagnostic gastroscopies. The primary outcome was the total mucosal visibility score(TMVS) which was evaluated using Mc Nally score. The sample size was calculated to be 24 per group(SD 2.4, 80% power, P < 0.05, 2-sample t test). RESULTS Fifty-four patients were randomised to receive either simethicone [1 m L liquid simethicone(100 mg) in 5 m L of water] or placebo(5 m L of water) at least 30 min before their gastroscopy. Six accredited consultants conductedthe gastroscopy, and the interobserver agreement of scoring TMVS was good with a Kappa statistic of 0.73. The simethicone group had significantly better mean TMVS compared to placebo(5.78 ± SD 1.65 vs 8.89 ± SD 1.97, P < 0.001). The improvement was statistically significant for the duodenum and the gastric antrum, angularis, body, and fundus. Percent 51.9 of patients in the simethicone group had a TMVS of 4(no bubbles at all) to 5(only 1 area with minimal bubbles), while in the placebo group 3.7% of patients had TMVS of 4 or 5. The number needed to treat was 2.1 to avoid a TMVS of 6 and more. The simethicone group also had a significantly shorter procedure time with less volume of additional flushes required during gastroscopy to clear away obscuring gastric foam.CONCLUSION With a premedication time of at least 30 min, 5 m L simethicone can significantly decrease gastric foam, decrease the volume of additional flushes, and shorten gastroscopy time. | Mingjun Song Andrew Boon Eu Kwek Ngai Moh Law Jeannie Peng Lan Ong Jessica Yi-Lyn Tan Prem Harichander Thurairajah Daphne Shih Wen Ang Tiing Leong Ang | 2016 | World Journal of Gastrointestinal Pharmacology and Therapeutics2016，7，4： | 10 |
| 2 | On-machine Precision Preparation and Dressing of Ball-headed Diamond Wheel for the Grinding of Fused Silica显示文摘In the grinding of high quality fused silica parts with complex surface or structure using ball-headed metal bonded diamond wheel with small diameter,the existing dressing methods are not suitable to dress the ball-headed diamond wheel precisely due to that they are either on-line in process dressing which may causes collision problem or without consideration for the effects of the tool setting error and electrode wear.An on-machine precision preparation and dressing method is proposed for ball-headed diamond wheel based on electrical discharge machining.By using this method the cylindrical diamond wheel with small diameter is manufactured to hemispherical-headed form.The obtained ball-headed diamond wheel is dressed after several grinding passes to recover geometrical accuracy and sharpness which is lost due to the wheel wear.A tool setting method based on high precision optical system is presented to reduce the wheel center setting error and dimension error.The effect of electrode tool wear is investigated by electrical dressing experiments,and the electrode tool wear compensation model is established based on the experimental results which show that the value of wear ratio coefficient K' tends to be constant with the increasing of the feed length of electrode and the mean value of K' is 0.156.Grinding experiments of fused silica are carried out on a test bench to evaluate the performance of the preparation and dressing method.The experimental results show that the surface roughness of the finished workpiece is 0.03 μm.The effect of the grinding parameter and dressing frequency on the surface roughness is investigated based on the measurement results of the surface roughness.This research provides an on-machine preparation and dressing method for ball-headed metal bonded diamond wheel used in the grinding of fused silica,which provides a solution to the tool setting method and the effect of electrode tool wear. | CHEN Mingjun LI Ziang YU Bo PENG Hui FANG Zhen | 2013 | Chinese Journal of Mechanical Engineering2013，26，5： | 5 |
| 3 | Spatio-temporal context for eodebook-based dynamic background subtraction 显示文摘 | WU MINGJUN PENG X1ANRONG | 2009 | AEU: International Journal of Electronics and Communications2009，64，8： | 1 |
| 4 | Spatio-temporal context for codebook-based dynamic background subtraction显示文摘 | Wu Mingjun Peng Xianrong | 2010 | AEU-International Journal of Electronics and Communications2010，64，： | 1 |
| 5 | Spatio-temporal Context for Codebook- based Dynamic Background Subtraction显示文摘 | Wu Mingjun Peng Xianrong | 2010 | International Journal of Electronics and Communications2010，64，8： | 1 |
| 6 | Characterization of three H5N5 and one H5N8 highly pathogenic avian influenza viruses in China显示文摘 | Kunkun Zhao Min Gu Lei Zhong Zhiqiang Duan Yan Zhang Yanmei Zhu Guo Zhao Mingjun Zhao Zhaoyang Chen Shunlin Hu Wenbo Liu Xiaowen Liu Daxin Peng Xiufan Liu | 2013 | Veterinary Microbiology (-)2013，，3： | 1 |
| 7 | Aerodynamic levitated laser annealing method to defective titanium dioxide with enhanced photocatalytic performance显示文摘因为它的缩小的乐队差距,有缺点的 TiO 2 在 photocatalytic 和电气化学的材料为使用吸引了增加的注意并且改进了可见光的 photocatalytic 活动。然而,为获得充满缺点的 TiO 2 的一条灵巧、有效的途径仍然是挑战。此处,我们表明如此的一条途径缩小它的 bandgap 并且通过由空气动力学的升在空中的激光退火植入丰富的缺点改进可见光的吸收(ALLA ) 处理。笔记 ALLA 方法不仅提供快速的退火,团结并且使过程凉下来,而且为同类、有缺点的 TiO 2 nanoparticles 展出高效率。退火激光的 TiO 2 完成 8.54 mmol 愠楮湯捩戠潬正挠灯汯浹牥洠捩汥敬瀠汯? 整瑲戭瑵汹愠牣汹瑡 ? 潣攭桴汹愠牣汹瑡 ? 潣洭瑥慨牣汹捩愠楣 ? 的高氢进化率 ? 呐 ?? 椠 ? 档獯湥愠 ?? 潭敬畣慬? 慣牲敩 ? 潦 ? 桴 ? 湩潣灲牯瑡潩 ? 景戠獩 ? 栭摹潲祸畱湩汯瑡 ? 稠湩 ? 娨煮猼'T 资 ? ??? 湡 ? 灯湥爭湩 ? 敭潲祣湡湩 ???? 敤潮整 ? 獡 ? 湚 ? ??? 猯'T??? 呐吗?? | Hehe Wei Xiaoguang Ma Liu Gu Jianqiang Li Wenjie Si Gang OU Wen Yu Chunsong Zhao Jiaying Li Mingjun Song Zhijian Peng Hui Wu | 2016 | Nano Research2016，9，12： | 1 |
| 8 | Calculated Structure,Elastic and Electronic Properties of Mg_2Pb at High Pressure显示文摘The effects of high pressure on structure,elastic and electronic properties of the intermetallic Mg_2Pb were calculated by the first-principles plane wave pseudo-potential method in the scheme of density functional theory(DFT)within the generalized gradient approximation.The elastic constants and Debye temperature obtained at 0 GPa are in good agreement with the available experiment data and other theoretical results.The electronic properties calculated suggest that the electronic density of states(DOS)at the Fermi level decreases under high pressure. | 段永华 Sun Yong Peng Mingjun Guo Zhongzheng Zhu Peixian | 2012 | Journal of Wuhan University of Technology(Materials Science)2012，27，2： | 1 |
| 9 | A Hu sheep genome with the first ovine Y chromosome reveal introgression history after sheep domestication显示文摘The Y chromosome plays key roles in male fertility and reflects the evolutionary history of paternal lineages.Here,we present a de novo genome assembly of the Hu sheep with the first draft assembly of ovine Y chromosome(o MSY),using nanopore sequencing and Hi-C technologies.The o MSY that we generated spans 10.6 Mb from which 775 Y-SNPs were identified by applying a large panel of whole genome sequences from worldwide sheep and wild Iranian mouflons.Three major paternal lineages(HY1a,HY1b and HY2)were defined across domestic sheep,of which HY2 was newly detected.Surprisingly,HY2 forms a monophyletic clade with the Iranian mouflons and is highly divergent from both HY1a and HY1b.Demographic analysis of Y chromosomes,mitochondrial and nuclear genomes confirmed that HY2 and the maternal counterpart of lineage C represented a distinct wild mouflon population in Iran that diverge from the direct ancestor of domestic sheep,the wild mouflons in Southeastern Anatolia.Our results suggest that wild Iranian mouflons had introgressed into domestic sheep and thereby introduced this Iranian mouflon specific lineage carrying HY2 to both East Asian and Africa sheep populations. | Ran Li Peng Yang Ming Li Wenwen Fang Xiangpeng Yue Hojjat Asadollahpour Nanaei Shangquan Gan Duo Du Yudong Cai Xuelei Dai Qimeng Yang Chunna Cao Weidong Deng Sangang He Wenrong Li Runlin Ma Mingjun Liu Yu Jiang | 2021 | Science China(Life Sciences)2021，64，7： | 1 |
| 10 | Anti-infection effects of heparin on SARS-CoV-2 in a diabetic mouse model显示文摘Severe acute respiratory syndrome coronavirus 2(SARSCo V-2)infection can result in more severe syndromes and poorer outcomes in patients with diabetes and obesity.However,the precise mechanisms responsible for the combined impact of coronavirus disease 2019(COVID-19)and diabetes have not yet been elucidated,and effective treatment options for SARS-Co V-2-infected diabetic patients remain limited.To investigate the disease pathogenesis,K18-h ACE2 transgenic(h ACE2^(Tg))mice with a leptin receptor deficiency(h ACE2-Lepr^(-/-))and high-fat diet(h ACE2-HFD)background were generated.The two mouse models were intranasally infected with a 5×10^(5) median tissue culture infectious dose(TCID_(50))of SARSCo V-2,with serum and lung tissue samples collected at 3days post-infection.The h ACE2-Lepr^(-/-)mice were then administered a combination of low-molecular-weight heparin(LMWH)(1 mg/kg or 5 mg/kg)and insulin via subcutaneous injection prior to intranasal infection with1×10^(4) TCID_(50)of SARS-Co V-2.Daily drug administration continued until the euthanasia of the mice.Analyses of viral RNA loads,histopathological changes in lung tissue,and inflammation factors were conducted.Results demonstrated similar SARS-Co V-2 susceptibility in h ACE2^(Tg)mice under both lean(chow diet)and obese(HFD)conditions.However,compared to the h ACE2-Lepr^(+/+)mice,h ACE2-Lepr^(-/-)mice exhibited more severe lung injury,enhanced expression of inflammatory cytokines and hypoxia-inducible factor-1α(HIF-1α),and increased apoptosis.Moreover,combined LMWH and insulin treatment effectively reduced disease progression and severity,attenuated lung pathological changes,and mitigated inflammatory responses.In conclusion,preexisting diabetes can lead to more severe lung damage upon SARS-Co V-2 infection,and LMWH may be a valuable therapeutic approach for managing COVID-19patients with diabetes. | Zhongyun Zhang Ning Zhang Xuancheng Lu Min Zhou Xiaoxiang Yan Weiqiong Gu Jingru Yang Qin Zhang Cheng Zhang Yuhuan Gong Mingjun Jia Xiaoyu Zhang Peng Ning Mei Liu Xiaoyan Li Xiaomeng Shi Wenjun Liu George FGao Guang Ning Jiqiu Wang Yuhai Bi | 2023 | Zoological Research2023，44，6： | 1 |
| 11 | Spatiotemporal context for code- book-based dyrmmic background subtraction 显示文摘 | Wu Mingjun Peng Xianrong | 2010 | Internation- al Journal of Electronics and Communications2010，64，8： | 1 |
| 12 | A numerical study of segmented cooling-stream injection in supersonic film cooling显示文摘The present study proposes a segmented cooling-stream injection structure based on a certain coolant mass flow rate,and numerically investigates the effect of segmented cooling-stream injection on supersonic film cooling.The results indicate that without shock-wave impingement and with helium as the coolant,segmented cooling-stream injection can reduce the mixing between the mainstream and the cooling stream to produce better cooling performance than single injection,especially at larger coolant Mach numbers.However,with nitrogen as the coolant,the cooling effect of the segmented-injection system is very close to that of the single-injection system.Mixing at the impinging region is enhanced significantly when there is an incident shock wave.When the shock wave impinges between the two coolant inlets,segmented cooling-stream injection improves film cooling effectiveness in the midstream and downstream regions more than single injection because only part of the cooling stream undergoes the enhanced mixing effect of the shock wave.The advantage of segmented injection is reduced when the impinging region is behind the second coolant inlet.The further downstream the impinging region,the smaller the associated advantage. | Hang NI Mingjun WANG Peixue JIANG Wei PENG Yinhai ZHU | 2022 | Chinese Journal of Aeronautics2022，35，6： | 1 |
| 13 | Study on coke dry quen- ching production and recycling of coking wastewater 显示文摘 | Shan Mingjun Yang Peng Pan Dawei | 2012 | Frontier of Environmental Science2012，1，1： | 1 |
| 14 | Spatio-temporal context for codebook-based dynamic background subtraction显示文摘 | Mingjun Wu Xianrong Peng | 2009 | AEUE - International Journal of Electronics and Communications2009，，8： | 1 |
| 15 | Spatio-temporal context for codebook-based dynamic background subtraction 显示文摘 | Wu Mingjun Peng Xianrong | 2010 | In- ternational Journal of Electronics and Communications2010，64，8： | 1 |
| 16 | The combination of methylenehydrofolate reductase C677T polymorphism screening and gastrointestinal tumor markers detection may be an early screening method for gastrointestinal cancer related to helicobacter pylori infection显示文摘Methyltetrahydrofolate reductase(MTHFR)is a key enzyme in folate metabolism,and its single nucleotide polymorphism(SNP)site C677T may be associated with gastrointestinal cancer.However,the relationship between MTHFR C677T polymorphism and gastrointestinal tumor markers carcinoma embryonic antigen(CEA),carbohydrate antigen 199(CA199)and carbohydrate antigen 724(CA724)in Helicobacter pylori(H.pylori)infection is not specified.This study aims to identify the association between MTHFR C677T polymorphism and gastrointestinal tumor markers(CEA,CA199 and CA724)in H.pylori infection.The relationship between MTHFR C677T polymorphism and gastrointestinal tumor markers in 58 patients with H.pylori infection and 94 non-infected patients was studied.We found that TT genotype was a susceptibility factor of H.pylori infection,which was also associated with increased CEA and CA724 levels.Moreover,there was a negative additive interaction between MTHFR gene C677T polymorphism and CEA levels in H.pylori infection.Meanwhile,there were significant differences in CEA levels between MTHFR C677T polymorphism and H.pylori infection.The presence of T allele led to a decrease in CEA levels when ^(13)C urea breath test(^(13)C-UBT)was positive,while the presence of T allele led to an increase in CEA levels when ^(13)C-UBT was negative.Therefore,we suggest that healthy people should take MTHFR C677T polymorphism screening,combined with ^(13)C-UBT and gastrointestinal tumor markers detection,which can screen out the susceptible population of H.pylori,and help to detect gastrointestinal cancer in the early stage. | Xiaoxing Wu Bin Peng Kun Qian Wei Zhang Jiang Min Mingjun Zhang Fanling Zeng Ziwei Wang | 2021 | Genes & Diseases2021，8，6： | 1 |
| 17 | Semantic segmentation for remote sensing images based on an AD-HRNet model显示文摘Semantic segmentation for remote sensing images faces challenges of unbalanced category weight,rich context causing difficulties of recognition,blurred boundaries of multi-scale objects,and so on.To address these problems,we propose a new model by combining HRNet with attention mechanisms and dilated convolution,denoted as:AD-HRNet for the semantic segmentation of remote sensing images.In the framework of AD-HRNet,we obtained the weight value of each category based on an improved weighted cross-entropy function by introducing the median frequency balance method to solve the issue of class weight imbalance.The Shuffle-CBAM module with channel attention and spatial attention in AD-HRNet framework was applied to extract more global context information of images through slightly increasing the amount of computation.To address the problem of blurred boundaries caused by multi-scale object segmentation and edge segmentation,we developed an MDC-DUC module in AD-HRNet framework to capture the context information of multi-scale objects and the edge information of many irregular objects.Taking Postdam,Vaihingen,and SAMA-VTOL datasets as materials,we verified the performance of AD-HRNet by comparing with eight typical semantic segmentation models.Experimental results shown that AD-HRNet increases the mIoUs to 75.59%and 71.58%based on the Postdam and Vaihingen datasets,respectively. | Xue Yang Xiang Fan Mingjun Peng Qingfeng Guan Luliang Tang | 2022 | International Journal of Digital Earth2022，15，1： | 0 |
| 18 | 分子筛限域合成亚纳米双金属簇Pd-M(OH)2(M=Ni,Co)催化剂实现高效产氢显示文摘文章简介课题组利用分子筛的纳米孔道限域效应,在水热条件下成功原位制备了纯硅分子筛Silicalite-1包覆亚纳米双金属Pd-M(OH)_2(M=Ni,Co)的催化剂。球差校正透射电镜测试结果表明,双金属Pd-Ni(OH)_2具有亚纳米尺寸,并限域在Silicalite-1分子筛的十元环交叉孔道。 | Qiming Sun Ning Wang Qiming Bing Rui Si Jingyao Liu Risheng Bai Peng Zhang Mingjun Jia 于吉红 | 2018 | 科学新闻2018，0，4： | 0 |
| 19 | Bitter receptor member TAS2R4 may have neurobiological function beyond acting as a bitter receptor显示文摘Among the five basic taste receptors of sweet,bitter,sour,salty,and umami,bitter receptors(TAS2Rs)are particularly important for animal survival because they have evolved as a central warning system to help avoid ingesting potentially toxic substances[1].TAS2R,belonging to G protein-coupled receptors(GPCRs)superfamily,can recognize varieties of bitter substances as ligands.TAS2Rs are different from many other GPCRs in that they are promiscuous and capable of binding with a wide range of compounds with relatively low specificity and affinity[2].TAS2Rs are expressed in many tissues,including respiratory tract,bladder,pancreas,testes,central nervous system,and the gastrointestinal tract in addition to the tongue[3,4]. | Hongling Zhu Lianyong Liu Li Ren Juan Chen Li Peng Chao Shi Xing Wang Shuanggang Hu Chaobao Zhang Mingjun Gu Xiangqi Li | 2020 | Acta Biochimica et Biophysica Sinica2020，52，4： | 0 |
| 20 | An integrated and efficient process for borax preparation and magnetite recovery from soda-ash roasted ludwigite ore under CO–CO_(2)–N_(2) atmosphere显示文摘To realize the comprehensive utilization of ludwigite ore,an integrated and efficient route for the boron and iron separation was proposed in this work,which via soda-ash roasting under CO–CO_(2)–N_(2) atmosphere followed by grind-leaching,magnetic separation,and CO_(2) carbonation.The effects of roasting temperature,roasting time,CO/(CO+CO_(2))composition,and Na_(2)CO_(3) dosage on the boron and iron separation indices were primarily investigated.Under the optimized conditions of the roasting temperature of 850℃,roasting time of 60 min,soda ash dosage of 20 wt%,and CO/(CO+CO_(2)) of 10 vol%,92%of boron was leached during wet grinding,and 88.6%of iron was recovered during the magnetic separation and magnetic concentrate with a total iron content of 61.51 wt%.Raman spectra and^(11)B NMR results indicated that boron exists asB(OH)_(4)^(-) in the leachate,from which high-purity borax pentahydrate could be prepared by CO_(2) carbonation. | Jinxiang You Jing Wang Mingjun Rao Xin Zhang Jun Luo Zhiwei Peng Guanghui Li | 2023 | International Journal of Minerals,Metallurgy and Materials2023，30，11： | 0 |
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