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| 1 | Recent Progress in Dual-Polarization Radar Research and Applications in China显示文摘Dual-polarization(dual-pol)radar can measure additional parameters that provide more microphysical information of precipitation systems than those provided by conventional Doppler radar.The dual-pol parameters have been successfully utilized to investigate precipitation microphysics and improve radar quantitative precipitation estimation(QPE).The recent progress in dual-pol radar research and applications in China is summarized in four aspects.Firstly,the characteristics of several representative dual-pol radars are reviewed.Various approaches have been developed for radar data quality control,including calibration,attenuation correction,calculation of specific differential phase shift,and identification and removal of non-meteorological echoes.Using dual-pol radar measurements,the microphysical characteristics derived from raindrop size distribution retrieval,hydrometeor classification,and QPE is better understood in China.The limited number of studies in China that have sought to use dual-pol radar data to validate the microphysical parameterization and initialization of numerical models and assimilate dual-pol data into numerical models are summarized.The challenges of applying dual-pol data in numerical models and emerging technologies that may make significant impacts on the field of radar meteorology are discussed. | Kun ZHAO Hao HUANG Mingjun WANG Wen-Chau LEE Gang CHEN Long WEN Jing WEN Guifu ZHANG Ming XUE Zhengwei YANG Liping LIU Chong WU Zhiqun HU Sheng CHEN | 2019 | Advances in Atmospheric Sciences2019，36，9： | 12 |
| 2 | Lipid-dependent conformational dynamics underlie the functional versatility of T-cell receptor显示文摘T 房间 receptor-CD3 建筑群(TCR ) 是能基于 CD3 细胞质的领域的各种各样的生物化学的变化开始抗原特定的有免疫力的回答的一台万用的发信号机器,但是内在的结构的基础留下逃犯。这里,我们开发了生物物理的途径学习 CD3 细胞质的领域的 conformational 动力学(CD3 CD ) 。在单个分子的水平,我们发现那 CD3 CD 能与三个功能的主题的不同坦诚有多重 conformational 状态,即, ITAM, BRS 和 PRS。因为,这些符合构造被产生 CD3 CD 有异构的类脂化合物绑定性质因此有异构的动力学。实时房间的成像实验证明不同抗原刺激能稳定 CD3 在不同符合构造的 CD 。类脂化合物依赖者 conformational 动力学因此为 TCR 的万用的发信号性质提供结构的基础。 | Xingdong Guo Chengsong Yan Hua Li Wenmao Huan Xiaoshan Shi Min Huang Yingfang Wang Weiling Pan Mingjun Cai Lunyi Li Wei Wu Yibing Bai Chi Zhang Zhijun Liu Xinyan Wang Xiaohui F Zhang Chun Tang Hongda Wang Wanli Liu Bo Ouyang Catherine C Wong Yi Cao Chenqi Xu | 2017 | Cell Research2017，27，4： | 5 |
| 3 | Effects of climate,land use and land cover changes on soil loss in the Three Gorges Reservoir area,China显示文摘Climate,land use and land cover(LULC)changes are among the primary driving forces of soil loss.Decoupling their effects can help in understanding the magnitude and trend of soil loss in response to human activities and ecosystem management.Here,the RUSLE model was applied to estimate the spatial-temporal variations of soil loss rate in the Three Gorges Reservoir(TGR)area during 2001-2015,followed by a scenario design to decouple the effects of climate and LULC changes.The results showed that increasing rainfall generated as much as 2.90×10^(7)t soil loss in the TGR area.However,such effect was offset by changes in LULC particularly afforestation,which retained about 1.10×10^(7)t soil annually.Other human activities such as dam development and urbanization aggravated soil loss by as much as 1.40×10^(6)t annually.Because of land use policies that favor economic development,distinct spatial variances of soil loss were observed in TGR area.Soil loss in some counties located downstream of the TGR area(i.e.,close to the dam)was more influenced by dam development,but soil loss in the other counties was more influenced by urbanization.As climate change(i.e.,increasing rainfall)did not affect plant performance in TGR area,our findings suggested that ecological restoration was more beneficial to curb the amount of soil loss caused by urbanization and dam construction. | Chunbo Huang Zhixiang Zhou Mingjun Teng Changguang Wu Pengcheng Wang | 2020 | Geography and Sustainability2020，1，3： | 3 |
| 4 | Urban-rural disparities in mild cognitive impairment and its functional subtypes among community- dwelling older residents in central China显示文摘background Substantial variations in the prevalence of mild cognitive impairment(MCI)and its subtypes have been reported,although mostly in geographically defined developed countries and regions.Less is known about MCI and its subtypes in rural areas of less developed central China.Aims The study aimed to compare the prevalence of MCI and its subtypes in residents aged 65 years or older in urban and rural areas of Hubei Province,China.Methods Participants aged 65 years or older were recruited between 2018 and 2019.Inperson structured interviews and clinical and neuropsychological assessments were performed at city health community centres and township hospitals.results Among 2644 participants without dementia,735 had MCI,resulting in a prevalence of 27.8%for total MCI,20.9%for amnestic MCI(aMCI)and 6.9%for non-amnestic MCI(naMCI).The prevalence of MCI in urban and rural areas was 20.2%and 44.1%,respectively.After adjusting for demographic factors,the prevalence of total MCI,aMCI and naMCI differed significantly between rural and urban areas(adjusted odds ratio(OR)2.10,1.44 and 3.76,respectively).Subgroup analysis revealed an association between rural socioeconomic and lifestyle disadvantage and MCI and its subtypes.Conclusions Our findings suggest that the prevalence of MCI among urban residents in central China is consistent with that in other metropolis areas,such as Shanghai,but the prevalence in rural areas is twice that in urban areas.Prospective studies and dementia prevention in China should focus on rural areas. | Dan Liu Lin Li Lina An Guirong Cheng Cong Chen Mingjun Zou Bo Zhang Xuguang Gan Lang Xu Yangming Ou Qingming Wu Ru Wang Yan Zeng | 2021 | General Psychiatry2021，34，5： | 3 |
| 5 | Theoretical and Experimental Research on Error Analysis and Optimization of Tool Path in Fabricating Aspheric Compound Eyes by Precision Micro Milling显示文摘Structure design and fabricating methods of three-dimensional(3D)artificial spherical compound eyes have been researched by many scholars.Micro-nano optical manufacturing is mostly used to process 3D artificial compound eyes.However,spherical optical compound eyes are less at optical performance than the eyes of insects,and it is difficult to further improve the imaging quality of compound eyes by means of micro-nano optical manufacturing.In this research,nonhomogeneous aspheric compound eyes(ACEs)are designed and fabricated.The nonhomogeneous aspheric structure is applied to calibrate the spherical aberration.Micro milling with advantages in processing three-dimensional micro structures is adopted to manufacture ACEs.In order to obtain ACEs with high imaging quality,the tool paths are optimized by analyzing the influence factors consisting of interpolation allowable error,scallop height and tool path pattern.In the experiments,two kinds of ACEs are manufactured by micro-milling with different too path patterns and cutting parameter on the miniature precision five-axis milling machine tool.The experimental results indicate that the ACEs of high surface quality can be achieved by circularly milling small micro-lens individually with changeable cutting depth.A prototype of the aspheric compound eye(ACE)with surface roughness(Ra)below 0.12?m is obtained with good imaging performance.This research ameliorates the imaging quality of 3D artificial compound eyes,and the proposed method of micro-milling can improve surface processing quality of compound eyes. | CHEN Mingjun XIAO Yong TIAN Wenlan WU Chunya CHU Xin | 2014 | Chinese Journal of Mechanical Engineering2014，27，3： | 3 |
| 6 | Research on the influence of machining introduced sub-surface defects and residue stress upon the mechanical properties of single crystal copper显示文摘Large scale molecular dynamics simulations of nanomachining and stretching of single crystal copper are performed to analyze the machining process’ influence on the material’s mechanical properties. The simulation results show that the machining process will introduce interfacial defects inside the specimen and enhance the compressive stress beneath the surface. Gener- ally speaking, interfacial defects lead to the decrease of the strength limit, while residue compressive stress can enhance the elastic limit and even the strength limit. Various machining parameters are adopted to investigate their influence on the me- chanical behavior of machined specimen. Lower cutting speed and smaller cutting depth lead to less defects and greater residue compressive stress, which brings about better mechanical properties. The elastic limit increases by 36.8% under the cutting depth of 0.73 nm and decreases by 21.1% under the cutting depth of 1.46 nm. The strength limit increases by 7.7% under the cutting speed of 100 m/s and decreases by 28.2% under the cutting speed of 300 m/s. | CHEN MingJun, XIAO GaoBo, CHEN JiaXuan & WU ChunYa Harbin Institute of Technology, Harbin 150001, China | 2010 | Science China(Technological Sciences)2010，53，12： | 3 |
| 7 | Physico-chemical Characteristics and Environmental Significance of Snow Deposition on Haxilegen Glacier No.51 in Tian Shan,China显示文摘Snow chemistry on the glaciers of alpine regions is a good indicator of atmospheric environmental change.We examine snow chemistry in three snowpits at different altitudes on the Haxilegen Glacier No.51,in the Kuitun River source,Tian Shan,China,during July-September 2004 to 2007.We use correlation analysis,factor analysis and sea-salt tracing methods to examine the characteristics and sources of major ions and mineral dust particles in the snow.Results show that mineral dust particles and major ions in the snow pits vary seasonally.During the Asian dust period in springtime,the concentration of mineral dust particles and major ions deposited in snow is high,while the concentration is relatively low during the non-dust period of summer and autumn.This may be caused by dust storm activity in central Asia.The order of major ionic concentrations in the snow packs was determined to be Ca2+ > SO42-> NH4+ > NO3-> Cl-> Na+ > Mg2+ > K+.Ca2+ was the dominant cation;SO42- was the dominant anion.We find,with the exception of NO3-,that the variabilities of ionic concentrations are highly correlated.Results show that the glacier region was significantly affected by dust activity and anthropogenic source.The major ions,especially Na+,originate from dust sources of central Asia and from the Ocean,transported by the westerly winds. | DONG Zhiwen LI Zhongqin ZHANG Mingjun WANG Feiteng WU Lihua | 2011 | Journal of Mountain Science2011，8，3： | 2 |
| 8 | Characteristics and Possible Formation Mechanisms of Severe Storms in the Outer Rainbands of Typhoon Mujigae(1522)显示文摘To better understand how severe storms form and evolve in the outer rainbands of typhoons, in this study, we investigate the evolutionary characteristics and possible formation mechanisms for severe storms in the rainbands of Typhoon Mujigae, which occurred during 2–5 October 2015, based on the NCEP–NCAR reanalysis data, conventional observations, and Doppler radar data. For the rainbands far from the inner core(eye and eyewall) of Mujigae(distance of approximately 70–800 km), wind speed first increased with the radius expanding from the inner core, and then decreased as the radius continued to expand. The Rankine Vortex Model was used to explore such variations in wind speed. The areas of strong stormy rainbands were mainly located in the northeast quadrant of Mujigae, and overlapped with the areas of high winds within approximately 300–550 km away from the inner core, where the strong winds were conducive to the development of strong storms. A severe convective cell in the rainbands developed into waterspout at approximately 500 km to the northeast of the inner core, when Mujigae was strengthening before it made landfall. Two severe convective cells in the rainbands developed into two tornadoes at approximately350 km to the northeast of the inner core after Mujigae made landfall. The radar echo bands enhanced to 60 d BZ when mesocyclones occurred in the rainbands and induced tornadoes. The radar echoes gradually weakened after the mesocyclones weakened. The tops of parent clouds of the mesocyclones elevated at first, and then suddenly dropped about 20 min before the tornadoes appeared. Thereby, the cloud top variation has the potential to be used as an early warning of tornado occurrence. | Bingyun WANG Ming WEI Wei HUA Yongli ZHANG Xiaohang WEN Jiafeng ZHENG Nan LI Han LI Yu WU Jie ZHU Mingjun ZHANG | 2017 | Journal of Meteorological Research2017，31，3： | 2 |
| 9 | Construction of WO_(3)/Ti-doped WO_(3)bi-layer nanopore arrays with superior electrochromic and capacitive performances显示文摘Crystalline WO_(3)/Ti-doped WO_(3)bi-layer nanopore arrays were constructed by the template synthesis of a WO_(3)nanopore layer modified by a magnetron sputtering of an amorphous Ti-doped/WO_(3)layer.The obtained bi-layer nanopore array shows a remarkable electrochromic performance with large dual-band optical modulation in both visible(VIS)and near infrared(NIR)regions(optical modulation of over 70%in the wavelength range from 600 to 1600 nm)and the fast response speed(coloring for 3.4 s and bleaching for 6.6 s).In addition,the bi-layer WO_(3)/Ti-doped WO_(3)nanopore array also present superior energy-storage properties(areal capacitance of 44.0 mF cm−2 and good rate capability),better than that of titanium-free thin films.The special bifunctional characteristics of electrochromism and pseudocapacitance can be ascribed to the large specific surface area provided by the architectural design,rich ion channels in the amorphous layer as well as proper titanium doping,which bestows the bi-layer nanopore array a great potential in clean energy applications. | Yingdi Shi Shujing Liu Yong Zhang Mingjun Sun Kai Tang Jiewu Cui Xia Shu Yan Wang Jiaqin Liu Yucheng Wu | 2019 | Tungsten2019，1，3： | 2 |
| 10 | DYRK1A suppression restrains Mcl-1 expression and sensitizes NSCLC cells to Bd-2 inhibitors显示文摘Objective:Mcl-1 overexpression confers acquired resistance to Bcl-2 inhibitors in non-small cell lung cancer(NSCLC),but no direct Mcl-1 inhibitor is currently available for clinical use.Thus,novel therapeutic strategies are urgently needed to target Mcl-1 and sensitize the anti-NSCLC activity of Bcl-2 inhibitors.Methods:Cell proliferation was measured using sulforhodamine B and colony formation assays,and apoptosis was detected with Annexin V-FITC staining.Gene expression was manipulated using siRNAs and plasmids.Real-time PCR and Western blot were used to measure mRNA and protein levels.Immunoprecipitation and immunofluorescence were used to analyze co-localization o f dual specificity tyrosine-phosphorylation-regulated kinase 1A(DYRK1A)and Mcl-1.Results:Suppression of DYRK1A resulted in reduced Mcl-1 expression in NSCLC cells,whereas overexpression of DYRK1A significantly increased Mcl-1 expression.Suppression of DYRK1A did not alter Mcl-1 mRNA levels,but did result in an accelerated degradation o f Mcl-1 protein in NSCLC cells.Furthermore,DYRK1A mediated proteasome-dependent degradation o f Mcl-1 in NSCLC cells,and DYRK1A co-localized with Mcl-1 in NSCLC cells and was co-expressed with Mcl-1 in tumor samples from lung cancer patients,suggesting that Mcl-1 may be a novel DYRK1A substrate.We showed that combined therapy with harmine and Bcl-2 antagonists significantly inhibited cell proliferation and induced apoptosis in NSCLC cell lines as well as primary NSCLC cells.Conclusions:Mcl-1 is a novel DYRK1A substrate,and the role of DYRK1A in promoting Mcl-1 stability makes it an attractive target for decreasing Bcl-2 inhibitor resistance. | Yangling Li Dongmei Zhou Shuang Xu Mingjun Rao Zuoyan Zhang Linwen Wu Chong Zhang Nengming Lin | 2020 | Cancer Biology & Medicine2020，17，2： | 2 |
| 11 | Multipurpose greenway planning for changing cities: a framework integrating priorities and a least-cost path model 显示文摘 | TENG Mingjun WU Changguang ZHOU Zhixiang | 2011 | Landsc Urban Plan2011，103，1： | 1 |
| 12 | Spatio-temporal context for eodebook-based dynamic background subtraction 显示文摘 | WU MINGJUN PENG X1ANRONG | 2009 | AEU: International Journal of Electronics and Communications2009，64，8： | 1 |
| 13 | Spatio-temporal context for codebook-based dynamic background subtraction显示文摘 | Wu Mingjun Peng Xianrong | 2010 | AEU-International Journal of Electronics and Communications2010，64，： | 1 |
| 14 | Spatio-temporal Context for Codebook- based Dynamic Background Subtraction显示文摘 | Wu Mingjun Peng Xianrong | 2010 | International Journal of Electronics and Communications2010，64，8： | 1 |
| 15 | Transferring conjugated poly (γ-glutamic acid-maleimide-co-L-lactide)-1,2-dipalmitoylsn-glycero-3-phosphoethanolamine copolymer nanoparticles for targeting drug delivery显示文摘 | Caiyan Zhao Xiaoguang Liu Junxing Liu Zhiwei Yang Xianghui Rong Mingjun Li Xingjie Liang Yan Wu | 2014 | Colloids and Surfaces B: Biointerfaces2014，，： | 1 |
| 16 | Effect of Atorvastatin on Serum MMP-2,MMP-9 and TIMP-1 in Rabbits with Chronic Heart Failure显示文摘Objective: To observe the effects of atorvastatin on serum matrix metalloproteinase-2(MMP-2), matrix metalloproteinase-9(MMP-9), and the tissue inhibitor of metalloproteinase-1(TIMP-1) in the development of chronic heart failure. To investigate the role of atorvastatin in the therapy of chronic heart failure and determine its possible mechanism of action. Methods: Thirty Japanese Big Ear rabbits were randomly selected and divided into 3 groups: sham-operated group(SO group), heart failure control group(HC group) and heart failure atorvastatin therapy group(HA group), with 6, 12 and 12 animals in the respective groups. Volume overloading was produced in the HC group and HA group animals by creating an aortic insufficiency, induced by damaging the aortic valve with a catheter introduced through the carotid artery. After 14 days, abdominal aorta constriction was performed in order to obtain a pressure overload. Six weeks later rabbits in the HA group were administered atorvastatin 3mg. Kg-1.d-1 for 4 weeks, at which time the experiment was terminated. Arterial blood was drawn and serum levels of MMP-2, MMP-9 and TIMP-1 were measured in all groups at the same time using an ELISA method. Results: Structural and functional indicators of chronic heart failure(CHF) were seen in both the HC and HA groups, but atorvastatin significantly reduced the observed effects. The serum concentrations of MMP-2, MMP-9 and TIMP-1 were at low levels in all three groups at the start of the study, with no difference between them(P < 0.05). At the end of 6th week concentrations were significantly increased in the HC and HA groups compared with the SO group(P < 0.05), but there were no differences between the HC group and HA group(P > 0.05). The increased concentrations in HC group continued to the end of the experiment, but values in the HA group were all lower than those in the HC group by the end of the experiment(P < 0.05). Conclusion: Serum concentrations of MMP-2, MMP-9 and TIMP-1 increase significantly during the course of CHF, paralleling the pathological progress of CHF. Atorvastatin benefits CHF, and the decreased serum levels of MMP-2, MMP- 9 and TIMP-1 may be one of the drug's mechanism of action. | Heng Jin Gang Zhao Mingjun Ma Hongping Wu Shouming Hua Zhihua Liu | 2008 | Journal of Nanjing Medical University2008，22，6： | 1 |
| 17 | Influence of highspeed dielectric spherical particles movement on its scattering characteristics 显示文摘 | WANG Mingjun WU Zhensen LI Yingle | 2007 | Chinese Optics Letters2007，5，4： | 1 |
| 18 | ROBUST CONTROL OF GAS TUNGSTEN ARC WELDING SYSTEM显示文摘为煤气的钨弧焊的柔韧的控制法律动态过程,它是一个典型样品数据系统并且充满不确定性,被介绍。由使用 Lyapunov 秒方法,为其内在的连续时间的系统受到结构化的不确定性的样品数据系统的一个类的柔韧的控制和柔韧的最佳的控制在时间域被讨论。作为结果,柔韧的稳定性和相应柔韧的控制法律的一些足够的条件被导出。所有这些结果被分别地与 LMI 限制解决线性矩阵不平等(LMI ) 的一个班和动态优化问题的一个班设计。一个例子在控制变量是焊接水池和控制可变脉搏责任比率的背后宽度的煤气的钨弧焊在系统的动态过程在一些试验性的条件下面适应了,被得出说明建议结果,采样时期是关键设计参数,这被显示出。 | WU Junfeng CHEN Shanben ZHANG Mingjun | 2007 | Chinese Journal of Mechanical Engineering2007，20，5： | 1 |
| 19 | Aerodynamic levitated laser annealing method to defective titanium dioxide with enhanced photocatalytic performance显示文摘因为它的缩小的乐队差距,有缺点的 TiO 2 在 photocatalytic 和电气化学的材料为使用吸引了增加的注意并且改进了可见光的 photocatalytic 活动。然而,为获得充满缺点的 TiO 2 的一条灵巧、有效的途径仍然是挑战。此处,我们表明如此的一条途径缩小它的 bandgap 并且通过由空气动力学的升在空中的激光退火植入丰富的缺点改进可见光的吸收(ALLA ) 处理。笔记 ALLA 方法不仅提供快速的退火,团结并且使过程凉下来,而且为同类、有缺点的 TiO 2 nanoparticles 展出高效率。退火激光的 TiO 2 完成 8.54 mmol 愠楮湯捩戠潬正挠灯汯浹牥洠捩汥敬瀠汯? 整瑲戭瑵汹愠牣汹瑡 ? 潣攭桴汹愠牣汹瑡 ? 潣洭瑥慨牣汹捩愠楣 ? 的高氢进化率 ? 呐 ?? 椠 ? 档獯湥愠 ?? 潭敬畣慬? 慣牲敩 ? 潦 ? 桴 ? 湩潣灲牯瑡潩 ? 景戠獩 ? 栭摹潲祸畱湩汯瑡 ? 稠湩 ? 娨煮猼'T 资 ? ??? 湡 ? 灯湥爭湩 ? 敭潲祣湡湩 ???? 敤潮整 ? 獡 ? 湚 ? ??? 猯'T??? 呐吗?? | Hehe Wei Xiaoguang Ma Liu Gu Jianqiang Li Wenjie Si Gang OU Wen Yu Chunsong Zhao Jiaying Li Mingjun Song Zhijian Peng Hui Wu | 2016 | Nano Research2016，9，12： | 1 |
| 20 | A novel sliding mode variable structure controller for cascade STATCOM显示文摘 | WU Junyong CHEN Qichao DU Mingjun | 2013 | IET Power Electronics2013，6，2： | 1 |
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