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| 1 | Network Pharmacology Evaluation Method Guidance-Draft显示文摘Foreword Note:Some of the document contents may involve certain patents,the identification of which is not the responsibility of the institution that releases the document.Main drafting organizations:Tsinghua University,Specialty Committee of Network Pharmacology of World Federation of Chinese Medicine Societies(WFCMS). | Shao Li Yi-Tao Chen Qing-Yang Ding Jian-Ye Dai Xian-Chun Duan Yuan-Jia Hu Xin-Xing Lai Qing-Fei Liu Ming Niu Rong-Wu Xiang Zheng Xiang Hai-Yu Xu Xin Wang Hong-Jun Yang Kuo Yang Ming Yang Hai-Yang Yu Bo Zhang Peng Zhang Qian-Ru Zhang Hui-Hui Zhao Jing Zhao | 2021 | World Journal of Traditional Chinese Medicine2021，7，1： | 32 |
| 2 | Generation of RAG 1- and 2-deficient rabbits by embryo microinjection of TALENs显示文摘 | Jun Song Juan Zhong Xiaogang Guo Yongqiang Chen Qingjian zou Jiao Huang Xiaoping Li Quanjun Zhang Zhiwu Jiang Chengcheng Tang Huaqiang Yang Tao Liu Peng Li Duanqing Pei Liangxue Lai | 2013 | Cell Research2013，23，8： | 15 |
| 3 | Hepaticojejunostomy for hepatolithiasis: A critical appraisal显示文摘瞄准:为肝石病的治疗评估长期的结果和肝管空肠吻合术(HJ ) 的外科的指示。方法:有肝石病,但是没有在过去的 10 年里对待的胆汁的苛评或膀胱的膨胀的 314 个选任的盒子回顾地被考察。病人根据胆汁的排水过程被划分成 HJ 组和 T 试管排水组。而且,四亚群被肝切除术作为一个平衡因素细分,组 A (1 ) :hepatectomy+HJ;组织 A (2 ) :choledochoctomy+HJ;组织 B (1 ) :肝切除术 + choledochoctomy T 试管排水;组织 B (2 ) :choledochoctomy + T 试管排水。石头剩余率,外科的功效和长期的结果在不同过程之中被比较。结果:在所有病人之中没有外科的死亡。全部的医院死亡是 1.6% 。在外科的清理以后的全面石头剩余率是 25.9% 。然而,在手术后的 choledochoscopic 碎石术以后以在外科的清理以后的石头剩余率 HJ 组和 T 试管排水组之间没有统计差别, T 试管排水组的全部的石头剩余率比 HJ 组的显著地低(0.5%对16.7%, P <
0.01 )。Hepatectomy + choledochoctomy 试管排水完成了最佳的治疗学的效果,仅仅 8.2% 病人手术后地受不了胆管炎的攻击,它比肝切除术 + HJ 的显著地低(8.2% 对 22.0% , P = 0.034 ) 。为手术后的胆管炎的主要原因是在 HJ 组剩余的石头(16/23, 70.0%) ,并且在 T 试管排水组的石头复发(34/35, 97.1%) 。起作用的时间显著地在那些经历的 HJ 被延长,并且 HJ 的起作用的病态比 T 试管排水的那些高。结论:为肝石病的 HJ 的治疗结果不由于剩余的石头和手术后的胆管炎的高率在这回顾的研究是令人满意的。HJ 不能有效地排干剩余石头。HJ 可以妨碍手术后的 choledochoscopic 碎石术,它是为手术后的剩余石头的最佳的管理。为肝石病的 HJ 的指示应该严格地被选择。 | Shao-Qiang Li Li-Jian Liang Bao-Gang Peng Jia-Ming Lai Ming-De Lu Dong-Ming Li | 2006 | World Journal of Gastroenterology2006，12，26： | 14 |
| 4 | TALEN-based generation of a cynomolgus monkey disease model for human microcephaly显示文摘基因在非人类的首领编辑可以为在人探索病原学和遗传上基于的神经病学的混乱的治疗学的策略导致珍贵模型。然而,仔细在人模仿病理学、行为的赤字的神经病学的混乱的一个猴子模型成功地还没被产生了。Microcephalin 1 (MCPH1 ) 在人的大脑,和智力迟钝伴随的 MCPH1 变化原因头小畸型的进化被含有。这里,我们产生了用抄写带 biallelic MCPH1 变化的一只 cynomolgus 猴子(Macaca fascicularis ) 像使活跃之物的受动器核酸酶。猴子概括了大多数在病人观察的重要临床的特征,包括在头圆周,早熟的染色体冷凝作用(PCC ) ,语料库 callosum 的发育不全和上面的手足 spasticity 的显著减小。而且,在变异的真皮的成纤维细胞的 MCPH1 的 overexpression 救了 PCC 症候群。这个猴子模型可以帮助我们阐明在人的头小畸型并且更好的致病的 MCPH1 的角色在首领大脑尺寸的进化理解这蛋白质的功能。 | Qiong Ke Weiqiang Li Xingqiang Lai Hong Chen Lihua Huang Zhuang Kang Kai Li Jie Ren Xiaofeng Lin Haiqing Zheng Weijun Huang Yunhan Ma Dongdong Xu Zheng Chen Xinming Song Xinyi Lin Min Zhuang Tao Wang Fengfeng Zhuang Jianzhong Xi Frank Fuxiang Mao Huimin Xia Bruce T Lahn Qi Zhou Shihua Yang Andy Peng Xiang | 2016 | Cell Research2016，26，9： | 13 |
| 5 | Highly reactive, flexible yet green Se precursor for metal selenide nanocrystals: Se-octadecene suspension (Se-SUS)显示文摘在 octadecene (Se 怀疑) 的好硒粉末(100 或 200 网孔) 的暂停证明了是一位高效的、万用的、方便的、可再现的、还绿的硒先锋。Se 怀疑的优点从它的高度反应的化学性质和灵活性产生。这二个特征使与多样的作文和结构执行高质量的金属硒化物 nanocrystals 的合成可能,包括二进制代码,核心 / 壳,做的转变金属,和复杂作文 nanocrystals。这些成功进一步证明 Se 怀疑是为在高质量的硒化物 nanocrystals 的合成解决一些长期的挑战的一位强大的 Se 先锋。例如,Se怀疑成功地作为一位 Se 先锋被采用因为在高质量的核心/壳 nanocrystals 轰炸生长代替昂贵、高度有毒的先锋,例如Se磷化氢和 bis-trimethylsilyl 硒化物,与极大地降低的取向附生的温度(象 150 一样低???????????????? | Chaodan Pu Jianhai Zhou Runchen Lai Yuan Niu Wennuan Nan Xiaogang Peng | 2013 | Nano Research2013，6，9： | 12 |
| 6 | Adjuvant heparanase inhibitor PI-88 therapy for hepatocellular carcinoma recurrence显示文摘AIM: To demonstrate that administering heparanase inhibitor PI-88 at 160 mg/d is safe and promising in reducing hepatocellular carcinoma(HCC) recurrence for up to 3 year following curative resection. METHODS: A total of 143 patients(83.1% of the 172 participants in the phase Ⅱ study) participated in the follow-up study. Of these patients, 50 had received no treatment, 48 had received 160 mg/d PI-88, and 45 had received 250 mg/d PI-88 during the phase Ⅱ trial. Safety parameters and the following efficacy endpoints were investigated:(1) time to recurrence;(2) diseasefree survival; and(3) overall survival. RESULTS: PI-88 at 160 mg/d delayed the onset and frequency of HCC recurrence, and provided a clinically significant survival advantage for up to 3 years after treatment compared with those of the control group:(1) the recurrence-free rate increased from 50% to 63%, and(2) time to recurrence at the 36 th percentile was postponed by 78%. The efficacy of administering PI-88 at 250 mg/d was confounded by a high dropout rate(11 out of 54 patients). Additionally, subgroup analyses of patients with(1) multiple tumors or a single tumor ≥ 2 cm; and(2) hepatitis B or C revealed that administering PI-88 at 160 mg/d conferred the most significant survival advantage(56.8% improvement in disease-free survival, P = 0.045) for patients with both risk factors for recurrence. CONCLUSION: Administering PI-88 at 160 mg/d is a safe and well-tolerated dosage that may confer significant clinical benefits for patients with HCC. | Chun-Jen Liu Juliana Chang Po-Huang Lee Deng-Yn Lin Cheng-Chung Wu Long-Bin Jeng Yih-Jyh Lin King-Tong Mok Wei-Chen Lee Hong-Zen Yeh Ming-Chih Ho Sheng-Shun Yang Mei-Due Yang Ming-Chin Yu Rey-Heng Hu Cheng-Yuan Peng Kuan-Lang Lai Stanley Shi-Chung Chang Pei-Jer Chen | 2014 | World Journal of Gastroenterology2014，20，32： | 11 |
| 7 | Molecular mechanisms of "off-on switch" of activities of human IDH1 by tumor-associated mutation R132H显示文摘人的 cytosolic NADP-IDH (IDH1 ) 最近被发现了涉及 tumorigenesis。尤其是,到目前为止识别的导出肿瘤的 IDH1 变化主要发生在 Arg132,和变化 R132H 是最流行的。这个变化损害酶的氧化 IDH 活动,但是显示把伪 - ketoglutarate (伪 K G ) 变换成 2-hydroxyglutarate 的新减小功能。这里,我们报导有或没有 isocitrate (ICT ) 的 R132H 变异的 IDH1 的结构跳了。和 mutagenesis 的结构的数据和生物化学的数据揭示一个以前未定义的起始的 ICT 有约束力的状态并且证明那项 IDH 活动要求一个 conformational 变化到一关门预先转移状态。Arg132 在催化反应起多重功能的作用;特别地, R132H 变化从起始的 ICT 有约束力的状态妨碍 conformational 变化到预先转移状态,导致 IDH 活动的缺陷。我们的结果第一次描述那有中间的符合构造,对应于一个起始的 ICT 有约束力的状态并且 R132H 变化能在这符合构造套住酶,因此使潜在地肿瘤镇压的 IDH 活动的鈥渙f f 开关鈥 ? 的分子的机制清楚些。而且,我们为获得的 伪K G 减小活动证明了 Tyr139 的必要性并且建议 Tyr139 可以由从 NADPH 在一个氢化物阴离子的转移期间在 伪K G 的 C2 原子上补偿增加的否定费用到 伪K G 起一个重要作用,它提供新卓见进 鈥渙n 开关鈥?的机制假设地由这个变化的 IDH1 的 oncogenic 减小活动。 | Bei Yang Chen Zhong Yingjie Peng Zheng Lai Jianping Ding | 2010 | Cell Research2010，20，11： | 11 |
| 8 | Synthesis of a benzoxazine monomer containing maleimide and allyloxy groups显示文摘新奇 benzoxazine 单体 3-(4-allyloxy )phenyl-3,4-dihydro-2H-6-(N-maleimido )-1,3-benzoxazine (AMB ) 被综合,结构被英尺红外证实,(1 ) H NMR。AMB 的热分析(DSC ) 证明烯丙氧基组的介绍减少了熔点并且展出了一扇狭窄、对称的治好的发热的窗户。 | Yan Tang Qing Lai Zhao Ke Zeng Pei Kai Miao Ke Zhou Wen Rui Tang Hong Fei Zhou Tao Liu Yi Peng Wang Gang Yang | 2007 | Chinese Chemical Letters2007，18，8： | 10 |
| 9 | A two-step lineage reprogramming strategy to generate functionally competent human hepatocytes from fibroblasts显示文摘Terminally differentiated cells can be generated by lineage reprogramming,which is,however,hindered by incomplete conversion with residual initial cell identity and partial functionality. Here, we demonstrate a new reprogramming strategy by mimicking the natural regeneration route, which permits generating expandable hepatic progenitor cells and functionally competent human hepatocytes. Fibroblasts were first induced into human hepatic progenitor-like cells (hHPLCs), which could robustly expand in vitro and efficiently engraft in vivo. Moreover, hHPLCs could be efficiently induced into mature human hepatocytes (hiHeps) in vitro, whose molecular identity highly resembles primary human hepatocytes (PHHs). Most importantly, hiHeps could be generated in large quantity and were functionally competent to replace PHHs for drug-metabolism estimation, toxicity prediction and hepatitis B virus infection modeling. Our results highlight the advantages of the progenitor stage for successful lineage reprogramming. This strategy is promising for generating other mature human cell types by lineage reprogramming. | Bingqing Xie Da Sun Yuanyuan Du Jun Jia Shicheng Sun Jun Xu Yifang Liu Chengang Xiang Sitong Chen Huangfan Xie Qiming Wang Guangya Li Xuehui LYU Hui Shen Shiyu Li Min Wu Xiaonan Zhang Yue Pu Kuanhui Xiang Weifeng Lai Peng Du Zhenghong Yuan Cheng Li Yan Shi Shichun Lu Hongkui Deng | 2019 | Cell Research2019，29，9： | 9 |
| 10 | PRGL:A cell wall proline-rich protein containning GASA domain in Gerbera hybrida显示文摘PRPs (proline-rich proteins) are a group of cell wall proteins characterized by their proline and hy- droproline-rich repetitive peptides. The expression of PRPs in plants is stimulated by wounding and environmental stress. GASA (gibberellic acid stimulated in Arabidopsis) proteins are small peptides sharing a 60 amino acid conserved C-terminal domain containing twelve invariant cysteine residues. Most of GASAs reported are localized to apoplasm or cell wall and their expression was regulated by gibberellins (GAs). It has been reported that, in French bean, these two proteins encoding by two distinct genes formed a two-component chitin-receptor involved in plant-pathogen interactions when plant was infected. We cloned a full-length cDNA of PRGL (proline-rich GASA-like) gene which encodes a protein containing both PRP and GASA-like domains. It is demonstrated that PRGL is a new protein with characteristics of PRP and GASA by analyzing its protein structure and gene expression. | PENG JianZong, LAI LiuJing & WANG XiaoJing College of Life Sciences, South China Normal University, Guangdong Provincial Key Lab of Biotechnology for Plant Development, Guangzhou 510631, China | 2008 | Science China(Life Sciences)2008，51，6： | 9 |
| 11 | Metal exposure and Alzheimer's pathogenesis.显示文摘 | Liu G Huang W Moir RD Vanderburg CR Lai B Peng Z Tanzi RE Rogers JT Huang X | 2006 | 中国生物学文摘2006，20，9： | 8 |
| 12 | Towards mass applications:A review on the challenges and developments in metallic bipolar plates for PEMFC显示文摘The industrial applications of proton exchange membrane fuel cell(PEMFC)technology have attracted tremendous capitals and research attention in the last ten years.However,there are still many bottlenecking problems before the progress triumphs.Among them,a core challenge is the improvement of bipolar plates(BPs).As a key component of PEMFC,the BPs undertake the crucial functions of distributing reactant gases and cooling medium,collecting the electricity generated,exporting waste products,etc.Due to the unique advantages of ultra-thin,high strength,easy-to-mass-produce,etc.,metallic BPs have been considered as the promising solution for the automotive and aerospace application scenarios with a strong requirement of power density.However,many challenges remain to be conquered in metallic BPs to fully meet all the requirements in those industrial applications such as corrosion,toxic ion emission and fabrication.The aim of this work is to provide an overview of the important researches in recent years dealing with the most critical problems of metallic BPs before industrial applications.The future studying directions in material and processing methods development are also given towards the wide application of metallic BP PEMFCs. | Zhutian Xu Diankai Qiu Peiyun Yi Linfa Peng Xinmin Lai | 2020 | Progress in Natural Science:Materials International2020，30，6： | 8 |
| 13 | The carbon nanotubes-based materials and their applications for organic pollutant removal: A critical review显示文摘The carbon nanotubes(CNTs) as the emerging materials for organic pollutant removal have gradually become a burgeoning research field.Herein,a mini-review of CNTs-based materials curre ntly studies for organic pollutant elimination is presented.This review summarizes the preparation methods of CNTsbased materials.CNTs-based materials can be used as adsorbents to remove organic pollutants in wastewater.The adsorption mechanisms mainly include surface diffusio n,pore diffusion and adsorption reaction.Most importantly,an in-depth overview of CNTs-based materials currently available in advanced oxidation processes(AOPs) applications for wastewater treatment is proposed.CNTs-based materials can catalyze different oxidants(e.g.,hydrogen peroxide(H2 O2),persulfates(PMS/PDS),ozone(O3) and ferrate/permanganate(Fe(Ⅵ)/Mn(Ⅶ)) to generate more reactive oxygen species(ROS) for organic pollutant elimination.Moreover,the possible reaction mechanisms of removing organic pollutants by CNTs-based materials are summarized systematically and discussed in detail.Finally,application potential and future research directions of CNTs-based materials in the environmental remediation field are proposed. | Jiali Peng Yongli He Chenying Zhou Shijun Su Bo Lai | 2021 | Chinese Chemical Letters2021，32，5： | 7 |
| 14 | Resveratrol induces AMPK and mTOR signaling inhibition-mediated autophagy and apoptosis in multiple myeloma cells显示文摘Resveratrol,a natural compound extracted from the skins of grapes,berries,or other fruits,has been shown to have anti-tumor effects against multiple myeloma(MM)via promoting apoptosis and inhibiting cell viability.In addition to apoptosis,autophagy also plays a significant role in anti-tumor effects.However,whether autophagy is involved in anti-MM activity of resveratrol remains unclear.In this study,human MM cell lines U266,RPMI-8226,and NCI-H929 were treated with resveratrol.Cell Counting Kit-8 assay and colony formation assay were used to measure cell viability.Western blot analysis was used to detect apoptosis-and autophagy-associated proteins.3-Methyladenine(3-MA)was applied to inhibit autophagy.Results showed that resveratrol inhibited cell viability and colony formation via promoting apoptosis and autophagy in MM cell lines U266,RPMI-8226,and NCI-H929.Resveratrol promoted apoptosis-related proteins,Caspase-3 activating poly-ADP-ribose polymerase and Caspase-3 cleavage,and decreased the protein level of Survivin in a dose-dependent manner.Additionally,resveratrol upregulated the levels of LC3 and Beclin1 in a dose-dependent way,indicating that autophagy might be implicated in anti-MM effect of resveratrol.Furthermore,3-MA relieved the cytotoxicity of resveratrol by blocking the autophagic flux.Resveratrol increased the phosphorylation of adenosine monophosphate(AMP)-activated protein kinase and decreased the phosphorylation of mammalian target of rapamycin(mTOR)and its downstream substrates p70S6K and 4EBP1 in a dose-dependent manner,leading to autophagy.Therefore,our results suggest that resveratrol exerts anti-MM effects through apoptosis and autophagy,which can be used as a new therapeutic strategy for MM in clinic. | Ruye Ma Dandan Yu Yu Peng Hongfei Yi Yingcong Wang Taofang Cheng Bingqing Shi Guang Yang Weiming Lai Xiaosong Wu Ye Lu Jumei Shi | 2021 | Acta Biochimica et Biophysica Sinica2021，53，6： | 7 |
| 15 | Dalbavancin binds ACE2 to block its interaction with SARS-CoV-2 spike protein and is effective in inhibiting SARS-CoV-2 infection in animal models显示文摘Infection with severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has caused a pandemic worldwide.Currently,however,no effective drug or vaccine is available to treat or prevent the resulting coronavirus disease 2019(COVID-19).Here,we report our discovery of a promising an ti-COVID-19 drug can didate,the lipoglycopeptide antibiotic dalbava ncin,based on virtual screening of the FDA-approved peptide drug library combined with in vitro and in vivo functional antiviral assays.Our results showed that dalbavancin directly binds to human angiotensin-converting enzyme 2(ACE2)with high affinity,thereby blocking its interaction with the SARS-CoV-2 spike protein.Furthermore,dalbavancin effectively prevents SARS-CoV-2 replication in Vero E6 cells with an EC50 of~12 nM.In both mouse and rhesus macaque models,viral replication and histopathological injuries caused by SARS-CoV-2 infection are significantly inhibited by dalbavancin administration.Given its high safety and long plasma half-life(8-10 days)shown in previous clinical trials,our data indicate that dalbavancin is a promising anti-COVID-19 drug candidate. | Gan Wang Meng-Li Yang Zi-Lei Duan Feng-Liang Liu Lin Jin Cheng-Bo Long Min Zhang Xiao-Peng Tang Ling Xu Ying-Chang Li Peter Muiruri Kamau Lian Yang Hong-Qi Liu Jing-Wen Xu Jie-Kai Chen Yong-Tang Zheng Xiao-Zhong Peng Ren Lai | 2021 | Cell Research2021，31，1： | 6 |
| 16 | Atomic Fe-Zn dual-metal sites for high-efficiency pH-universal oxygen reduction catalysis显示文摘An effective electrocatalyst being highly active in all pH range for oxygen reduction reaction(ORR)is crucial for energy conversion and storage devices.However,most of the high-efficiency ORR catalysis was reported in alkaline conditions.Herein,we demonstrated the preparation of atomically dispersed Fe-Zn pairs anchored on porous N-doped carbon frameworks(Fe-Zn-SA/NC),which works efficiently as ORR catalyst in the whole pH range.It achieves high half-wave potentials of 0.78,0.85 and 0.72 V in 0.1 M HClO4,0.1 M KOH and 0.1 M phosphate buffer saline(PBS)solutions,respectively,as well as respectable stability.The performances are even comparable to Pt/C.Furthermore,when assembled into a Zn-air battery,the high power density of 167.2 mWcm−2 and 120 h durability reveal the feasibility of Fe-Zn-SA/NC in real energy-related devices.Theoretical calculations demonstrate that the superior catalytic activity of Fe-Zn-SA/NC can be contributed to the lower energy barriers of ORR at the Fe-Zn-N6 centers.This work demonstrates the potential of Fe-Zn pairs as alternatives to the Pt catalysts for efficient catalytic ORR and provides new insights of dual-atom catalysts for other energy conversion related catalytic reactions. | Jie Xu Shuhua Lai Defeng Qi Min Hu Xianyun Peng Yifan Liu Wei Liu Guangzhi Hu Heng Xu Fan Li Chao Li Jia He Longchao Zhuo Jiaqiang Sun Yuan Qiu Shusheng Zhang Jun Luo Xijun Liu | 2021 | Nano Research2021，14，5： | 6 |
| 17 | Synthesis and characterization of phosphate-modified LiMn_2O_4 cathode materials for Li-ion battery显示文摘LiMn2O4 尖晶石阴极材料与 2 wt.% LiMPO4 被修改(M = 公司, Ni, Mn ) 由 polyol 合成方法。修改表面的 LiMn2O4 阴极材料身体上是的磷酸盐由 X 光检查衍射(XRD ) 描绘了,扫描电子显微镜学(SEM ) 和精力散 X 光检查光谱学(版本) 。chargedischarge 测试证明骑车和 LiMn2O4 阴极材料的率能力被与磷酸盐稳定电极表面显著地提高。 | Qing Lai Jiang Ke Du Yan Bing Cao Zhong Dong Peng Guo Rong Hu Ye Xiang Liu | 2010 | Chinese Chemical Letters2010，21，11： | 6 |
| 18 | A hybrid carbon aerogel with both aligned and interconnected pores as interlayer for high-performance lithium-sulfur batteries显示文摘在硫电极上创造的 polysulfide 种类的可溶的性质严重地妨碍了锂硫(Li-S ) 的电气化学的表演电池。套住并且抛锚的 polysulfides 为克服这个问题正在答应途径。在这个工作,有排列并且相连的毛孔的机械地柔韧的、电子上传导性的混合的碳 aerogel (HCA ) 为 Li-S 电池作为夹层被创造并且调查。层次 cross-linked 网络由表和碳 nanotubes 能作为一张因特网扮演捕获 polysulfide 的 graphene 构造了,当在 aerogel 内的 microand nano 毛孔能便于电解质的快穿入和锂离子的快速的运输时。作为唯一的结构的优点和活跃材料的体积变化的优秀住所, 1,309 mAh | Mingkai Liu Zhibin Yang Hao Sun Chao Lai Xinsheng Zhao Huisheng Peng Tianxi Liu | 2016 | Nano Research2016，9，12： | 6 |
| 19 | Synthesis and biological evaluation of nitric oxide-releasing sixalkoxyl biphenyl derivatives as anticancer agents显示文摘A series of novel nitric oxide-donating sixalkoxyl biphenyl derivatives (14a-l) were synthesized by coupling furoxan with alkoxyl biphenyl skeleton using amino acids as the spacers, and their cytotoxicity against HepG2 cells in vitro were evaluated by MTT method. It was found that 14c, 14d, 14f, 14i, 14j and 14k showed more potent cytotoxic activities than control 5-?uorouracil. NO release assay of target compounds indicated that the maximum amount of NO released by most active compounds 14c and 14j was about 6 10 2 mmol/L, whereas 14a and 14h with very weak activity only released NO of 1 10 2 mmol/L. | Xiang Wen Kong Yi Hua Zhang Li Dai Hui Ji Yi Sheng Lai Si Xun Peng | 2008 | Chinese Chemical Letters2008，19，2： | 5 |
| 20 | Elective neck dissection or "watchful waiting": optimal management strategy for early stage NO tongue carcinoma using decision analysis techniques显示文摘背景尽管舌头癌症是头和颈的普通疾病,在选任的颈解剖并且“警惕等待”之间的颈治疗的选择与早舞台为病人仍然保持争论没有口头的舌头 carcinoma.Methods 根据头和颈癌症的当前的状态,一个决定分析模型被创造为早舌头 cancer.Expected 价值( EV )比较二治疗策略根据遇见了定义 criteria.Sensitivity | SONG Tao BI Nan GUI Lai PENG Zhe | 2008 | Chinese Medical Journal2008，，17： | 5 |
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