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| 1 | Cold-chain food contamination as the possible origin of COVID-19 resurgence in Beijing显示文摘COVID-19,caused by SARS-CoV-2[1,2],has been contained in China through stringent non-pharmaceutical interventions.Border control and quarantine have effectively prevented the virus from being spread by infected travellers,but the risk of resurgence caused by other routes of introduction and transmission remains unclear,and current strategies to prevent resurgence could be flawed.Since July,SARS-CoV-2 RNA contaminations in frozen food imported from countries with ongoing epidemics have been reported in nine provinces in China[3,4].However,there is no robust evidence of COVID-19 outbreaks initiated by environmentto-human transmission.Here we add to evidence of such transmission by investigating the recent COVID-19 resurgence in Beijing. | Xinghuo Pang Lili Ren Shuangsheng Wu Wentai Ma Jian Yang Lin Di Jie Li Yan Xiao Lu Kang Shichang Du Jing Du Jing Wang Gang Li Shuguang Zhai Lijuan Chen Wenxiong Zhou Shengjie Lai Lei Gao Yang Pan Quanyi Wang Mingkun Li Jianbin Wang Yanyi Huang Jianwei Wang COVID-19 Field Response Group COVID-19 Laboratory Testing Group | 2020 | National Science Review2020，7，12： | 51 |
| 2 | Treponema pallidum-specific antibody expression for the diagnosis of different stages of syphilis显示文摘 | SUN Ran LAI Di-hui REN Rong-xin LIAN Shi ZHANG Hai-ping | 2013 | Chinese Medical Journal2013，，2： | 23 |
| 3 | Antimicrobial peptides: new hope in the war against multidrug resistance显示文摘The discovery of antibiotics marked a golden age in the revolution of human medicine. However,decades later, bacterial infections remain a global healthcare threat, and a return to the pre-antibiotic era seems inevitable if stringent measures are not adopted to curb the rapid emergence and spread of multidrug resistance and the indiscriminate use of antibiotics. In hospital settings, multidrug resistant(MDR) pathogens, including carbapenem-resistant Pseudomonas aeruginosa, vancomycin-resistant enterococci(VRE), methicillin-resistant Staphylococcus aureus(MRSA), and extendedspectrum β-lactamases(ESBL) bearing Acinetobacter baumannii, Escherichia coli, and Klebsiella pneumoniae are amongst the most problematic due to the paucity of treatment options,increased hospital stay, and exorbitant medical costs. Antimicrobial peptides(AMPs) provide an excellent potential strategy for combating these threats. Compared to empirical antibiotics, they show low tendency to select for resistance, rapid killing action, broad-spectrum activity, and extraordinary clinical efficacy against several MDR strains. Therefore, this review highlights multidrug resistance among nosocomial bacterial pathogens and its implications and reiterates the importance of AMPs as next-generation antibiotics for combating MDR superbugs. | James Mwangi Xue Hao Ren Lai Zhi-Ye Zhang | 2019 | Zoological Research2019，40，6： | 23 |
| 4 | Comprehensive assessment on dynamic roof instability under fractured rock mass conditions in the excavation disturbed zone显示文摘The damage process of fractured rock mass showed that the fracture in rocks induced roof collapse in Yangchangwan Coal Mine,China. The rock mass was particularly weak and fractured. There occurred 6 large-scale dynamical roof falls in the excavation disturbed zone(EDZ) with the collapsing volume of 216 m3. First,the field detailed geological environment,regional seismic dynamics,and dynamic instability of roadways were generally investigated. Second,the field multiple-index monitoring measurements for detecting the deep delamination of the roof,convergence deformation,bolt-cable load,acoustic emission(AE) characteristic parameters,total AE events,AE energy-releasing rate,rock mass fracture,and damage were arranged. Finally,according to the time-space-strength relations,a quantitative assessment of the influence of rock-mass damage on the dynamic roof instability was accomplished. | Xing-ping Lai Fen-hua Ren Yong-ping Wu Mei-feng Cai | 2009 | International Journal of Minerals,Metallurgy and Materials2009，16，1： | 19 |
| 5 | TALEN-based generation of a cynomolgus monkey disease model for human microcephaly显示文摘基因在非人类的首领编辑可以为在人探索病原学和遗传上基于的神经病学的混乱的治疗学的策略导致珍贵模型。然而,仔细在人模仿病理学、行为的赤字的神经病学的混乱的一个猴子模型成功地还没被产生了。Microcephalin 1 (MCPH1 ) 在人的大脑,和智力迟钝伴随的 MCPH1 变化原因头小畸型的进化被含有。这里,我们产生了用抄写带 biallelic MCPH1 变化的一只 cynomolgus 猴子(Macaca fascicularis ) 像使活跃之物的受动器核酸酶。猴子概括了大多数在病人观察的重要临床的特征,包括在头圆周,早熟的染色体冷凝作用(PCC ) ,语料库 callosum 的发育不全和上面的手足 spasticity 的显著减小。而且,在变异的真皮的成纤维细胞的 MCPH1 的 overexpression 救了 PCC 症候群。这个猴子模型可以帮助我们阐明在人的头小畸型并且更好的致病的 MCPH1 的角色在首领大脑尺寸的进化理解这蛋白质的功能。 | Qiong Ke Weiqiang Li Xingqiang Lai Hong Chen Lihua Huang Zhuang Kang Kai Li Jie Ren Xiaofeng Lin Haiqing Zheng Weijun Huang Yunhan Ma Dongdong Xu Zheng Chen Xinming Song Xinyi Lin Min Zhuang Tao Wang Fengfeng Zhuang Jianzhong Xi Frank Fuxiang Mao Huimin Xia Bruce T Lahn Qi Zhou Shihua Yang Andy Peng Xiang | 2016 | Cell Research2016，26，9： | 13 |
| 6 | Experimental small bowel preservation using Polysol: A new alternative to University of Wisconsin solution, Celsior and histidine-tryptophan-ketoglutarate solution?显示文摘AIM: To evaluate the potential of Polysol, a newly developed preservation solution, in cold storage of small bowel grafts, compared with the current standards, University of Wisconsin solution (UW), Celsior and histidine-tryptophan-ketoglutarate solution (HTK). METHODS: Male Wistar rats were used as donors. Small bowels were retrieved, flushed and then stored in the respective 4 solutions for 18 h at 4℃. Functional integrity of the grafts was evaluated by isolated reperfusion with oxygenated Krebs-Henseleit buffer at 37℃ for 30 min in all 4 groups. RESULTS: Polysol preservation exhibited the highest tissue ATP concentration and the lowest release of LDH. Malondialdehyde, an index for tissue lipid peroxidation, was also the lowest in Polysol. Tissue oxygen consumption was significantly higher in Polysol than in the others. Of interest, UW-storage promoted 10-fold higher apoptosis than in the others. Moreover, electron microscopy revealed that the mucosal villi/micro-villi formation and the cell organelles, including mitochondria, were both significantly better preserved in Polysol, while deleterious alterations were apparent in the others, most notably in UW. Although Celsior and HTK exhibited the better trend of results than UW in some parameters, but could not reach the over-all superiority to UW.CONCLUSION: Cold storage using Polysol resulted in significantly better integrity and function of small bowel grafts than UW. Hence, Polysol may be a novel alternative for the small bowel preservation. | Lai Wei Koichiro Hata Benedict Marie Doorschodt Reinhard Büttner Thomas Minor René H Tolba | 2007 | World Journal of Gastroenterology2007，13，27： | 9 |
| 7 | Simulation experiment of AE-based localization damage and deformation characteristic on covering rock in mined-out area显示文摘The localization damage and deformation characteristics of multiple rock in mined-out area under thick soil layer were investigated by acoustic emission (AE)-based physical similar simulation experiment and damage test combined with the AE theory on rock damage. During different mining courses, the degree of wall rock suffered from mining disturbed process in mined-out area was different, so did the AE density of initial damage and fracture. Some characteristic parameters, including large events, total events, and energy rate, presented fluctuations with temporal and spatial change and take on a certain extent statistic relation. Subsequently, the percent of damage degree was defined and divided into 4 stages, and the localization damage and deformation character- istics of surrounding rock in mined-out area and coal pillars were analyzed quantitatively. | Sheng-jun Miao Xing-ping Lai Xing-guang Zhao Fen-hua Ren | 2009 | International Journal of Minerals,Metallurgy and Materials2009，16，3： | 6 |
| 8 | Isolation and identification of symbiotic bacteria from the skin, mouth, and rectum of wild and captive tree shrews显示文摘Endosymbionts influence many aspects of their hosts’ health conditions, including physiology, development, immunity, metabolism, etc. Tree shrews(Tupaia belangeri chinensis) have attracted increasing attention in modeling human diseases and therapeutic responses due to their close relationship with primates. To clarify the situation of symbiotic bacteria from their body surface, oral cavity, and anus, 12 wild and 12 the third generation of captive tree shrews were examined. Based on morphological and cultural characteristics, physiological and biochemical tests, as well as the 16 S rDNA full sequence analysis, 12 bacteria strains were isolated and identified from the wild tree shrews: body surface: Bacillus subtilis(detection rate 42%), Pseudomonas aeruginosa(25%), Staphlococcus aureus(33%), S. Epidermidis(75%), Micrococcus luteus(25%), Kurthia gibsonii(17%); oral cavity: Neisseria mucosa(58%), Streptococcus pneumonia(17%); anus: Enterococcus faecalis(17%), Lactococus lactis(33%), Escherichia coli(92%), Salmonella typhosa(17%); whereas, four were indentified from the third generation captive tree shrews: body surface: S. epidermidis(75%); oral cavity: N.mucosa(67%); anus: L. lactis(33%), E. coli(100%). These results indicate that S. epidermidis, N. mucosa, L. lactis and E. coli were major bacteria in tree shrews, whereas, S. aureus, M. luteus, K. gibsonii, E. faecalis and S. typhosa were species-specific flora. This study facilitates the future use of tree shrews as a standard experimental animal and improves our understanding of the relationship between endosymbionts and their hosts. | Gui LI Ren LAI Gang DUAN Long-Bao LYU Zhi-Ye ZHANG Huang LIU Xun XIANG | 2014 | Zoological Research2014，35，6： | 6 |
| 9 | Comparison of Clinical Effects between Percutaneous Transluminal Septal Myocardial Ablation and Modified Morrow Septal Myectomy on Patients with Hypertrophic Cardiomyopathy显示文摘 | Hong-Chang Guo Jin-Hua Li Teng-Yong Jiang Chang-Wei Ren Jiang Dai Yu-Jie Zhou Yong-Qiang Lai | 2018 | Chinese Medical Journal2018，，5： | 6 |
| 10 | Dalbavancin binds ACE2 to block its interaction with SARS-CoV-2 spike protein and is effective in inhibiting SARS-CoV-2 infection in animal models显示文摘Infection with severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has caused a pandemic worldwide.Currently,however,no effective drug or vaccine is available to treat or prevent the resulting coronavirus disease 2019(COVID-19).Here,we report our discovery of a promising an ti-COVID-19 drug can didate,the lipoglycopeptide antibiotic dalbava ncin,based on virtual screening of the FDA-approved peptide drug library combined with in vitro and in vivo functional antiviral assays.Our results showed that dalbavancin directly binds to human angiotensin-converting enzyme 2(ACE2)with high affinity,thereby blocking its interaction with the SARS-CoV-2 spike protein.Furthermore,dalbavancin effectively prevents SARS-CoV-2 replication in Vero E6 cells with an EC50 of~12 nM.In both mouse and rhesus macaque models,viral replication and histopathological injuries caused by SARS-CoV-2 infection are significantly inhibited by dalbavancin administration.Given its high safety and long plasma half-life(8-10 days)shown in previous clinical trials,our data indicate that dalbavancin is a promising anti-COVID-19 drug candidate. | Gan Wang Meng-Li Yang Zi-Lei Duan Feng-Liang Liu Lin Jin Cheng-Bo Long Min Zhang Xiao-Peng Tang Ling Xu Ying-Chang Li Peter Muiruri Kamau Lian Yang Hong-Qi Liu Jing-Wen Xu Jie-Kai Chen Yong-Tang Zheng Xiao-Zhong Peng Ren Lai | 2021 | Cell Research2021，31，1： | 6 |
| 11 | RegIV expression showing specificity to gastrointestinal tract and its potential role in diagnosing digestive tract neuroendocrine tumor显示文摘Regenerating gene IV (RegIV),a member of the regenerating gene family discovered in 2001,has been found to be involved in malignancy in several different organs including the stomach,colorectum,pancreas and prostate,but the overall expression profile of RegIV has not been reported. To learn more about RegIV,we evaluated its distribution by immunohistochemistry (IHC) in a total of 360 samples including 24 types of normal tissue,40 benign and malignant lesions,and 18 neuroendocrine tumors. We found that in normal tissues,in addition to its relative specificity for the gastrointestinal tract,RegIV was detected in the adrenal gland and mammary gland. Among all the malignancies of various histological types under evaluation,RegIV was found mostly in adenocarcinomas. Studies on additional sets of colorectal tumor samples showed that RegIV expression was predominant in colorectal adenoma (87.5%) and peritumoral tissue (100%) but not in cancer tissue (30.8%). Among neuroendocrine tumors,RegIV had a relatively restricted expression to those of digestive system. | Feng-ying LI Xiao-bin REN En-ping XU Qiong HUANG Hong-qiang SHENG Bing-jian LV Mao-de LAI | 2010 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2010，11，4： | 5 |
| 12 | Dynamic destabilization analysis based on AE experiment of deep-seated,steep-inclined and extra-thick coal seam显示文摘No.5 coal seam in Huating Coal Mine is a deep-seated,steep-inclined extra-thick coal seam where excavation disturbance is quite frequent.The maximum and minimum principal stresses differ widely.During mining,dynamical destabilization happens frequently and induce tragedies.Based on the comparison between the acoustic emission(AE)experiment on dynamical destabiliza- tion of coal rock and the related in situ testing results,this article provides comprehensive analysis on the regular quantificational AE patterns(energy rate,total events)of coal rock destabilization in complex-variable environment.The comparison parameters include dynamic tension energy rate,deformation resistance to compression,and shear stress. | Fenhua Ren Xmgpmg Lai Meifeng Cai | 2008 | Journal of University of Science and Technology Beijing2008，15，3： | 5 |
| 13 | 从E级计算到Z级计算的新挑战与新技术(英文)显示文摘高性能计算已成为促进传统与新兴领域科技创新取得进展的基础设施。随着高性能计算的发展,E级系统(每秒1018次浮点运算)预计2020年前后投入使用。实现E级计算后的10年(2020–2030)将成为E级计算向Z级计算(每秒1021次浮点运算)过渡的关键时期,计算能力提升将面临前所未有的挑战。从硬件和软件方面分析未来高性能计算的挑战,展望后E级计算时代的技术发展与革新,并提出未来实现E级计算向Z级计算过渡的可行性建议。 | Xiang-ke LIAO Kai LU Can-qun YANG Jin-wen LI Yuan YUAN Ming-che LAI Li-bo HUANG Ping-jing LU Jian-bin FANG Jing REN Jie SHEN | 2018 | Frontiers of Information Technology & Electronic Engineering2018，19，10： | 5 |
| 14 | Purification and characterization of a novel anti-coagulant from the leech Hirudinaria manillensis显示文摘Protease inhibitors have been reported rarely from the leech Hirudinaria manillensis.In this study,we purified a novel protease inhibitor(bdellin-HM-2)with anticoagulant properties from H.manillensis.With a molecular weight of 1.4x104,bdellin-HM-2 was also characterized with three intra?molecular disulfide bridges at the N-terminus and multiple HHXDD and HXDD motifs at theC-terminus.cDNAcloning revealed that the putative nucleotide-encoding protein of bdellin-HM-2 contained 132 ami no acids and was encoded by a 399 bp open reading frame(ORF).Sequence alignment showed that bdellin-HM-2 shared similarity with the“non-classical'Kazal-type serine protease inhibitors,but had no inhibitory effect on trypsin,elastase,chymotrypsin,kallikrein,factor Xlla(FXIIa),factor Xia(FXIa),factor Xa(FXa),thrombin,or plasmin.Bdellin-HM-2 showed anticoagulant effects by proIonging the activated partial thromboplastin time(aPTT),indicating a role in enabling H.manillensis to obtain a blood meal from its host.Our results suggest that bdellin-HM丒2 may play a crucial role in blood-sucking in this leech species and may be a pote ntial can didate for the development of clinical anti-thrombotic drugs. | Ruo-Mei Cheng Xiao-Peng Tang Ai-Lin Long James Mwangi Ren Lai Rui-Pu Sun Cheng-Bo Long Zhen-Qing Zhang | 2019 | Zoological Research2019，40，3： | 5 |
| 15 | Metallogenic Mechanism and Tectonic Setting of Tungsten Mineralization in the Yangbishan Deposit in Northeastern China显示文摘The Yangbishan iron–tungsten deposit in the Shuangyashan area of Heilongjiang Province is located in the center of the Jiamusi Massif in northeastern China. The rare earth element and trace element compositions of the scheelite show that it formed in a reducing environment and inherited the rare earth element features of the ore-forming fluid. The geochemical characteristics of the gneissic granite associated with the tungsten mineralization show that the magma formed in this reducing environment and originated from the partial melting of metamorphosed shale that contained organic carbon and was enriched with tungsten. In addition, in situ Hf isotopic analysis of zircons from the gneissic granite indicates that they probably originated from the partial melting of a predominantly Paleo–Mesoproterozoic crustal source. According to LA-ICP-MS zircon dating, the Yangbishan orerelated gneissic granite has an Early Paleozoic crystallization age of 520.6 ± 2.8 Ma. This study, together with previous data, indicates that the massifs of northeastern China, including Erguna, Xing'an, Songliao, Jiamusi, and Khanka massifs, belonged to an orogenic belt that existed along the southern margin of the Siberian Craton during the late Pan-African period. The significant continental movements of this orogeny resulted in widespread magmatic activity in northeastern China from 530 Ma to 470 Ma under a tectonic setting that transitioned from compressional syn-collision to extensional postcollision. | HAO Yujie REN Yunsheng ZHAO Hualei LAI Ke ZHAO Xuan MA Yupeng | 2018 | Acta Geologica Sinica(English Edition)2018，92，1： | 4 |
| 16 | Comparison of outcomes after human leukocyte antigen-matched and haploidentical hematopoietic stem-cell transplantation for multiple myeloma显示文摘Background:Allogeneic stem-cell transplantation (SCT) is a well-established immunotherapeutic strategy for multiple myeloma (MM) with a potent and often sustained graft-vs.-myeloma effect.This multicenter investigation aimed to analyze the complications and survival of haploidentical SCT in patients with MM,and compare the main outcomes with matched-related donors (MRDs).Methods:Haploidentical and MRD SCT was identified from a cohort of 97 patients with MM who received a myeloablative transplantation in 13 hospitals from May 2001 to December 2017.A matched-pair analysis was designed.For each haplo recipient,the recipients were randomly selected from the MRD group and were matched according to the following criteria:year of the hematopoietic SCT (±2 years),disease status at transplantation,and the length of follow-up.ults:Seventy cases received MRD and 27 received haploidendcal transplantation.The two groups showed no significant ifferences regarding age,gender,cytogenetic risk,and diagnostic stage.The cumulative incidences of non-relapse mortality (NRM) at1 and 3 years based on donor type were 20.5%(95% confidence interval [CI],10.90-30.10%) and 24.2%(95% CI,13.81-34.59%) for the MRD group and 16.80%(95% CI,1.71-31.89%) and 28.70%(95% CI,8.71-48.69%) for the haplo group,respectively.Cumulative incidence of NRM did not differ significantly between the two groups (x2 =0.031,P =0.861).The cumulative incidences of progression-free survival (PFS) and 1 year and 3 years by type of donors were 59.8 %(95 % CI,48.24-71.36 %) and 45.4 %(95 % CI,33.44-57.36%),and 65.6%(95% CI,47.18-84.02%) and 26.8%(95% CI,7.59-46.01%) for MRD and haploidentical donor,respectively.Cumulative incidence of PFS did not differ significantly between the two groups (x2 =0.182,P =0.670).In multivariate analyses,no statistically significant differences were observed between haploidentical and MRD for relapse,NRM,PFS,and overall survival.There were no statistically differences on main outcomes after haploidentical and MRD.Conclusion:Haploidentical SCT could be performed safely and feasibly for patients with MM in need. | Yao Chen Wei-Jun Fu Lan-Ping Xu Han-Yun Ren Yong-Rong Lai Dai-Hong Liu Lin Liu Zi-Min Sun Yuan-Bin Wu Xin Wang Ling-Hui Xia Ming Jiang Tong-Lin Hu Ding-Ming Wan Xiao-Jun Huang | 2019 | Chinese Medical Journal2019，，15： | 4 |
| 17 | Antimicrobial peptide LL-37 forms complex with bacterial DNA to facilitate blood translocation of bacterial DNA and aggravate ulcerative colitis显示文摘Bacterial DNA(bacDNA) is frequently found in serum of patient with ulcerative colitis(UC) and Crohn's disease, even blood bacterial culture is negative. How bacDNA evades immune elimination and is translocated into blood remain unclear. Here, we showed that bacDNA avoids elimination and disables bacteriakilling function of antimicrobial peptide LL-37(Cramp in mice) by forming complex with LL-37, which is inducible after culture with bacteria or bacterial products. Elevated LL-37-bacDNA complex was found in plasma and lesions of patients with UC. LL-37-bacDNA promoted inflammation by inducing Th1, Th2 and Th17 differentiation and activating toll-like receptor-9(TLR9). The complex also increased paracellular permeability, which possibly combines its inflammatory effects to promote local damage and bacDNA translocation into blood. Cramp-bacDNA aggravated mouse colitis severity while interference with the complex ameliorated the disease. The study identifies that inflammatogenic bacDNA utilizes LL-37 as a vehicle for blood translocation and to evade immune elimination. Additionally, bacteria may make a milieu by releasing bacDNA to utilize and resist host antimicrobial peptides as a ‘trojan horse'. | Zilei Duan Yaqun Fang Yang Sun Ning Luan Xue Chen Mengrou Chen Yajun Han Yizhu Yin James Mwangi Junkun Niu Kunhua Wang Yinglei Miao Zhiye Zhang Ren Lai | 2018 | Science Bulletin2018，63，20： | 4 |
| 18 | 3’-Methoxydaidzein exerts analgesic activity by inhibiting voltage-gated sodium channels显示文摘Isoflavones are widely consumed by people around the world in the form of soy products, dietary supplements and drugs. Many isoflavones or related crude extracts have been reported to exert pain-relief activities, but the mechanism remains unclear. Voltage-gated sodium channels(VGSCs) play important roles in excitability of pain sensing neurons and many of them are important nociceptors. Here, we report that several isoflavones including 3’-methoxydaidzein(3 MOD), genistein(GEN) and daidzein(DAI) show abilities to block VGSCs and thus to attenuate chemicals and heat induced acute pain or chronic constriction injury(CCI) induced pain hypersensitivity in mice. Especially, 3 MOD shows strong analgesic potential without inducing addiction through inhibiting subtypes NaV1.7, NaV1.8 and NaV1.3 with the IC50 of 181 ± 14, 397 ± 26, and 505 ± 46 nmol·L–1, respectively, providing a promising compound or parent structure for the treatment of pain pathologies. This study reveals a pain-alleviating mechanism of dietary isoflavones and may provide a convenient avenue to alleviate pain. | XU Run-Jia FEI Shuo-Han CHEN Lin-Yan WANG Gan LIU Ming ZHANG Wen-Sheng YAN Xiu-Wen LAI Ren SHEN Chuan-Bin | 2019 | Chinese Journal of Natural Medicines2019，17，6： | 4 |
| 19 | Research on Coupling Relationship between Social Economy and Ecological Environment in Jinghe County of Aiby Lake Basin,Xinjiang显示文摘Based on the theory of sustainable development,using the theory and method of coupling relationship,the main city of Aiby Lake basin——Jinghe County in Xinjiang is selected. Based on the analyses of natural condition,population growth,land use type and ecological environment,the comprehensive evaluation index systems of socio-economic development level and eco-environment quality in Jinghe County are constructed. Using principal component analysis,a comprehensive evaluation of socio-economic development level and ecological environment quality in Jinghe County is conducted by combining with Excel. Their coupling relationship is studied,and quantitative coordination degree between social economy and ecological environment in Jinghe County is obtained. The results show that in recent 50 years,socio-economic development level in Jinghe County is rising,but the ecological environment quality is falling. Their coupling degree C changes during [- 1. 260, + 0. 482],in other words,their coupling relationship is changing between ' reluctant coordination' and ' not coordination'. After entering into the 21 stcentury,their coupling relationship is basically ' reluctant coordination'. On this basis,the existing problems in the process of sustainable development in Jinghe County are analyzed,and the suggestions about promoting coordinated development between social economy and ecological environment are put forward. | Lai Fengbing Sun Hu Chen Shujiang Ren Shuang | 2014 | Meteorological and Environmental Research2014，5，11： | 4 |
| 20 | Quantitative analysis of biotechnical reinforcement for a steep slope consisting of composite coal-gangue-soil medium adjacent to a mined-out area显示文摘The engineering and geological characteristics of a steep slope consisting of coal gangue, rock and soil medium in Hua- ting coal mine have been comprehensively investigated. Owing to humid weather, heavy rainfall, vegetation and porous characteris- tics of the soil and rock mass, the steep slope will be destabilized and induce mud-rock flow or derive hazard easily. Firstly, based on the classical slope reinforcement theory, some regularity between the shear and displacement in the destabilized zone of the slope with or without root strength contribution is presented. Then, based on the experimental and statistical analysis of root strength, hy- drological characteristics and stability status, etc., some possible biotechnical techniques for reinforcement of the steep slope have been suggested. These methods are important for quantitative analysis of destabilization of the slope and design of the biotechnical reinforcement. | Xingping Lai Mowen Xie Fenhua Ren Meifeng Cai | 2005 | Journal of University of Science and Technology Beijing2005，12，6： | 3 |
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