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| 1 | Timing of laparoscopic cholecystectomy for acute cholecystitis: A prospective non randomized study显示文摘AIM: To study the timing of laparoscopic cholecy- stectomy for patients with acute cholecystitis.METHODS: Between January 2002 and December 2005, all American Society of Anesthesiologists classification (ASA)—RESULTS: One hundred and twenty-nine patients underwent laparoscopic cholecystectomy for acute cholecystitis during the index admission. Thirty six were assigned to group 1, 58 to group 2, and 35 to group 3. The conversion rate and morbidity for the whole cohort of patients were 4.6% and 10.8%, respectively. There was no significant difference in the conversion rate, morbidity and postoperative hospital stay between the three groups.CONCLUSION: Laparoscopic cholecystectomy for acute cholecystitis during the index admission is safe, regardless of the time elapsed from the onset of symptoms. This policy can result in an overall shorter hospitalization. | George Tzovaras Dimitris Zacharoulis Paraskevi Liakou Theodoros Theodoropoulos George Paroutoglou Constantine Hatzitheofilou | 2006 | World Journal of Gastroenterology2006，12，34： | 11 |
| 2 | Development of a hybrid photoacoustic and optical monitoring system for the study of laser ablation processes upon the removal of encrustation from stonework显示文摘In the context of this work,a prototype hybrid photoacoustic(PA)and optical system for the on-line monitoring of laser cleaning procedures is presented.The developed apparatus has enabled the detection of MHz frequency range acoustic waves generated during the laser ablation process.The intrinsically generated PA signals combined with high resolution optical images provide the opportunity to follow the cleaning process accurately and in real time.Technical mock-ups have been used to demonstrate the potential of this novel technique with emphasis given to applications that refer to the restoration of Cultural Heritage(CH)surfaces.Towards this purpose,the real time monitoring of the laser assisted removal of unwanted encrustation from stonework has been achieved using IR and UV wavelengths.This novel approach has allowed for the precise determination of the critical number of laser pulses required for the elimination of the encrustation layer,while highlighting the dominant ablation mechanisms according to the irradiation wavelength.The promising results obtained using the prototype hybrid PA and optical system can open up new perspectives in the monitoring of laser cleaning interventions,promoting an improved restoration outcome. | Athanasia Papanikolaou George JTserevelakis Kristalia Melessanaki Costas Fotakis Giannis Zacharakis Paraskevi Pouli | 2020 | Opto-Electronic Advances2020，3，2： | 11 |
| 3 | Prevalence of occult hepatitis B virus infection in haemodialysis patients from central Greece显示文摘AIM:To assess the hepatitis B virus(HBV)-DNA and the prevalence of occult HBV infection in end-stage renal failure(ESRF)patients from Central Greece. METHODS:Sera from 366 ESRF patients attending five out of six dialysis units from Central Greece were investigated for HBV-DNA by real-time polymerase chain reaction.Only serum samples with repeatedly detectable HBV-DNA were considered positive.IgG antibodies to hepatitis C virus(anti-HCV)were tested by a third generation enzyme linked immunosorbent assay(ELISA),while IgG antibodies to hepatitis E virus (anti-HEV)were tested by two commercially available ELISAs.RESULTS:HBV-DNA was detected in 15/366 patient (4.1%)and HBsAg in 20/366(5.5%).The prevalenc of occult HBV infection was 0.9%(3/346 HBsAg negative patients).Occult HBV was not associate with a specific marker of HBV infection or anti-HCV o anti-HEV reactivity.There was no significant differenc in HBV-DNA titres,demographic and biochemica features,between patients with occult HBV infectio and those with HBsAg-positive chronic HBV infection. CONCLUSION:In central Greece,4%of ESRF patient had detectable HBV-DNA,though in this setting,th prevalence of occult HBV seems to be very low(0.9%). | Paraskevi Mina Sarah P Georgiadou Christos Rizos George N Dalekos Eirini I Rigopoulou | 2010 | World Journal of Gastroenterology2010，16，2： | 8 |
| 4 | Effects of mycophenolate mofetil vs cyclosporine administration on graft survival and function after islet allotransplantation in diabetic rats显示文摘AIM: To develop an experimental model of islet allotransplantation in diabetic rats and to determine the positive or adverse effects of MMF as a single agent. METHODS: Thirty-six male Wistar rats and 18 male Lewis rats were used as recipients and donors respectively. Diabetes was induced by the use of streptozotocin (60 mg/kg) intraperitoneally. Unpurified islets were isolated using the collagenase digestion technique and transplanted into the splenic parenchyma. The recipients were randomly assigned to one of the following three groups: group A (control group) had no immunosuppression; group B received cyclosporine (CsA) (5 mg/kg); group C receivedmycophenolate mofetil (MMF) (20 mg/kg). The animalswere killed on the 12th d. Blood and grafted tissues were obtained for laboratory and histological assessment. RESULTS: Median allograft survival was significantly higher in the two therapy groups than that in the controls (10 and 12 d for CsA and MMF respectively vs 0 d for the control group, P<0.01). No difference in allograft survival between the CsA and MMF groups was found. However,MMF had less renal and hepatic toxicity and allowed weight gain.CONCLUSION: Monotherapy with MMF for immunosu ppression was safe in an experimental model of islet allotransplantation and was equally effective with cyclosporine, with less toxicity. | Constantin Fotiadis Paraskevi Xekouki Apostolos E Papalois PantelisT Antonakis Ioannis Sfiniadakis Dimitrios Flogeras Eleutheria Karampela George Zografos | 2005 | World Journal of Gastroenterology2005，11，18： | 7 |
| 5 | Spatial analysis and evaluation of a coal deposit by coupling AHP & GIS techniques显示文摘Nowadays,the evaluation of coal deposits becomes crucial,due to many uncontrollable factors,which affect the energy sector.A comparative evaluation of coal deposits is essential for their hierarchical classification regarding their sustainable exploitation,when compared to other coal deposits or competitive fuels,which may be used as alternative solutions for electricity generation.In this paper,a method for spatial analysis and evaluation of a lignite deposit is proposed,by creating four spatial key indicators via GIS analysis,which are then aggregated by applying a weighted linear combination.The analytical hierarchy process is applied to estimate the relative weights of the indicators,in order to perform a weighted cartographic overlay.Through the synthesis of the indicators,an overall,total spatial quality indicator is calculated.The weighted analysis was shown to be more effective compared to the unweighted one,because it can provide more reliable results regarding the exploitation of the examined lignite deposit.The implementation of GIS-based analytical hierarchy process in spatial analysis and evaluation of lignite deposits,in terms of sustainable exploitation,demonstrates that this method can be extensively applied for evaluating the economic potential of mineral deposits. | Nikolaos Paraskevis Christos Roumpos Nikolaos Stathopoulos Aikaterini Adam | 2019 | International Journal of Mining Science and Technology2019，29，6： | 7 |
| 6 | Percutaneous trans-hepatic bilateral biliary stenting in Bismuth Ⅳ malignant obstruction显示文摘AIM: To investigate the clinical efficiency of percutaneous trans-hepatic bilateral biliary metallic stenting for the management of Bismuth Ⅳ malignant obstructive disease. METHODS: Our hospital's database was searched for all patients suffering from the inoperable malignant biliary obstruction Bismuth Ⅳ, and treated with percutaneous bilateral trans-hepatic placement of selfexpandable nitinol stents. The indication for percutaneous stenting was an inoperable, malignant, symptomatic, biliary obstruction. An un-correctable coagulation disorder was the only absolute contra-indication for treatment. Bismuth grading was performed using magnetic resonance cholangiopancreatography. Computed tomography evaluation of the lesion and the dilatation status of the biliary tree was always performed prior to the procedure. All procedures were performed under conscious sedation. A single trans-hepatic track technique was preferred (T-configuration stenting) and a second, contra-lateral trans-hepatic track (Y-configuration stenting) was used only in cases of inability to access the contra-lateral lobe using a single track technique. The study's primary endpoints were clinical success, defined as a decrease in bilirubin levels within 10 d and patient survival rates. Secondary endpoints included peri-procedural complications, primary and secondary patency rates. RESULTS: A total of 35 patients (18 female, 51.4%) with a mean age 69 ± 13 years (range 33-88) were included in the study. The procedures were performed between March 2000 and June 2008 and mean time follow-up was 13.5 ± 22.0 mo (range 0-96). The underlying malignant disease was cholangiocarcinoma (n = 10), hepatocellular carcinoma (n = 9), pancreatic carcinoma (n = 5), gastric cancer (n = 2), bile duct tumor (n = 2), colorectal cancer (n = 2), gallbladder carcinoma (n = 2), lung cancer (n = 1), breast cancer (n = 1) or non-Hodgkin lymphoma (n = 1). In all cases, various self-expandable bare metal stents with diameters ranging from 7 to 10 mm were used. Stents were placed in Y-configuration in 24/35 cases (68.6%) using two stents in 12/24 patients and three stents in 12/24 cases (50%). A T-configuration stent placement was performed in 11/35 patients (31.4%), using two stents in 4/11 cases (36.4%) and three stents in 7/11 cases (63.6%). Follow-up was available in all patients (35/35). Patient survival ranged from 0 to 1763 d and the mean survival time was 168 d. Clinical success rate was 77.1% (27/35 cases), and peri-procedural mortality rate was 5.7% (2/35 patients). Biliary reobstruction due to stent occlusion occurred in 25.7% of the cases (9/35 patients), while in 7/11 (63.6%) one additional percutaneous re-intervention due to stent occlusion resulting in clinical relapse of symptomatology was successfully performed. In the remaining 4/11 patients (36.4%) more than 1 additional reintervention was performed. The median decrease of total serum bilirubin was 60.5% and occurred in 81.8% of the cases (27/33 patients). The median primary and secondary patency was 105 (range 0-719) and 181 d (range 5-1763), respectively. According to the KaplanMeyer survival analysis, the estimated survival rate was 73.5%, 47.1% and 26.1% at 1, 6 and 12 mo respectively, while the 8-year survival rate was 4.9%. Major and minor complication rates were 5.7% (2/35 patients) and 17.1% (6/35 patients), respectively. CONCLUSION: Percutaneous bilateral biliary stenting is a safe and clinically effective palliative approach in patients suffering from Bismuth Ⅳ malignant obstruction. | Dimitrios Karnabatidis Stavros Spiliopoulos Paraskevi Katsakiori Odissefs Romanos Konstantinos Katsanos Dimitrios Siablis | 2013 | World Journal of Hepatology2013，5，3： | 4 |
| 7 | Association of arterial stiffness with coronary flow reserve in revascularized coronary artery disease patients显示文摘AIM: To investigate the association of arterial wave reflection with coronary flow reserve(CFR) in coronary artery disease(CAD) patients after successful revascularization.METHODS: We assessed 70 patients with angiographically documented CAD who had undergone recent successful revascularization. We measured(1) reactive hyperemia index(RHI) using fingertip peripheral arterial tonometry(RH-PAT Endo-PAT);(2) carotid to femoral pulse wave velocity(PWVc-Complior);(3) augmentation index(AIx), the diastolic area(DAI%) and diastolic reflection area(DRA) of the central aortic pulse wave(Arteriograph);(4) CFR using Doppler echocardiography; and(5) blood levels of lipoprotein-phospholipase A2(LpPLA2).RESULTS: After adjustment for age, sex, blood pressure parameter, lipidemic, diabetic and smoking status, we found that coronary flow reserve was independently related to AIx(b =-0.38, r = 0.009), DAI(b = 0.36, P = 0.014), DRA(b = 0.39, P = 0.005) and RT(b =-0.29,P = 0.026). Additionally, patients with CFR < 2.5 had higher PWVc(11.6 ± 2.3 vs 10.2 ± 1.4 m/s, P = 0.019), SBPc(139.1 ± 17.8 vs 125.2 ± 19.1 mm Hg, P = 0.026), AIx(38.2% ± 14.8% vs 29.4% ± 15.1%, P = 0.011) and lower RHI(1.26 ± 0.28 vs 1.50 ± 0.46, P = 0.012), DAI(44.3% ± 7.9% vs 53.9% ± 6.7%, P = 0.008), DRA(42.2 ± 9.6 vs 51.6 ± 11.4, P = 0.012) and Lp PLA2(268.1 ± 91.9 vs 199.5 ± 78.4 ng/m L, P = 0.002) compared with those with CFR ≥ 2.5. Elevated Lp PLA2 was related with reduced CFR(r =-0.33, P = 0.001), RHI(r =-0.37, P < 0.001) and DRA(r =-0.35, P = 0.001) as well as increased PWVc(r = 0.34, P = 0.012) and AIx(r = 0.34, P = 0.001). CONCLUSION: Abnormal arterial wave reflections are related with impaired coronary flow reserve despite successful revascularization in CAD patients. There is a common inflammatory link between impaired aortic wall properties, endothelial dysfunction and coronary flow impairment in CAD. | Vlassis Tritakis Stavros Tzortzis Ignatios Ikonomidis Kleanthi Dima Georgios Pavlidis Paraskevi Trivilou Ioannis Paraskevaidis Giorgos Katsimaglis John Parissis John Lekakis | 2016 | World Journal of Cardiology2016，8，2： | 4 |
| 8 | Sildenafil versus continuous positive airway pressure for erectile dysfunction in men with obstructive sleep apnea: a comparat-ive study of their efficacy and safety and the patient's satisfaction with treatment显示文摘瞄准:与妨碍的睡觉呼吸暂停(OSA ) 在并发的可勃起的机能障碍(编辑) 的治疗估计 sildenafil 和连续积极航线压力(CPAP ) 的功效,并且在病人和他们的 partners.Methods 计量治疗满足的水平:四十个人与 sildenafil 被对待 12 个星期 100 mg (20 个人) 或 CPAP 在夜间期间睡觉(20 个人) 。治疗功效被成功的交际尝试的率估计,并且对治疗的满足被病人估计“并且搭挡”询问 1 个可勃起的机能障碍的答案治疗盘点满足。结果:Undersildenafil, 249 中的 128 个(51.4%) 交际尝试是成功的;在 CPAP 下面,(26.9%) 193 中的 51 个尝试是成功的(~ cP <
0.001 ) 。可勃起的功能在两个组被改进。Aftersildenafil 和 CPAP 治疗,为可勃起的功能领域的吝啬的国际索引获得 were14.3 并且 10.8,分别地(~ bP = 0.025 ) ,与 7.8 和 7 相比在基线分别地。CPAPand sildenafil 很好被容忍。在 CPAP 和短暂头疼下面的鼻音干的分散的事件并且在 sildenafil 下面涌出不是重要的。百分之五十个病人对待 withsildenafil, 25% 与治疗对 CPAP 满意,并且他们的搭挡同等地满足。为在 sildenafil 下面的病人和搭挡的满足分数比在 CPAP 下面的那些优异(~ cP <
0.002 ) 。结论:两 sildenafil 100 mg 和 CPAP,独立使用,有积极治疗学的影响,但是 sildenafil 是优异的。病人和他们的搭挡是然而为编辑的治疗对 sildenafil 满意的更多,因为不满足的人的高比例,搭挡,新治疗学的代理人或二个方法的联合必须进一步被学习。 | Petros Perimenis Kyriakos Karkoulias Angelis Konstantinopoulos Paraskevi P. Perimeni George Katsenis Anastasios Athanasopoulos Konstantinos Spyropoulos | 2007 | Asian Journal of Andrology2007，9，2： | 3 |
| 9 | Different pain scores in single transumbilical incision laparoscopic cholecystectomy versus classic laparoscopic cholecystectomy: a randomized controlled trial显示文摘 | Evangelos C. Tsimoyiannis Konstantinos E. Tsimogiannis George Pappas-Gogos Charalampos Farantos Nikolaos Benetatos Paraskevi Mavridou Adamantia Manataki | 2010 | Surgical Endoscopy2010，，8： | 3 |
| 10 | Pulmonary fibrosis and emphysema: Is the emphysema type associated with the pattern of fibrosis?显示文摘AIM: To investigate whether the predominant emphysema type is associated with the high resolution computed tomography(HRCT) pattern of fibrosis in combined pulmonary fibrosis and emphysema(CPFE).METHODS: Fifty-three smokers with upper lobe emphysema and lower lobe pulmonary fibrosis on- HRCT-were retrospectively evaluated. Patients were stratified into 3 groups according to the predominant type of emphysema: Centrilobular(CLE), paraseptal(PSE), CLE = PSE. Patients were also stratified into 3 other groups according to the predominant type of fibrosis on HRCT: Typical usual interstitial pneumonia(UIP), probable UIP and nonspecific interstitial pneumonia(NSIP). HRCTs were scored at 5 predetermined levels for the coarseness of fibrosis(Coarseness), extent of emphysema(emphysema), extent of interstitial lung disease(Tot Ext ILD), extent of reticular pattern not otherwise specified(Ret NOS), extent of ground glass opacity with traction bronchiectasis(extG GOBx), extent of pure ground glass opacity and extent of honeycombing. HRCT mean scores, pulmonary function tests, diffusion capacity(DLCO) and systolic pulmonary arterial pressure were compared among the groups.RESULTS: The predominant type of emphysema was strongly correlated with the predominant type of fibrosis. The centrilobular emphysema group exhibited a significantly higher extent of emphysema(P < 0.001) and a lower extent of interstitial lung disease(P < 0.002), reticular pattern not otherwise specified(P < 0.023), extent of ground glass opacity with traction bronchiectasis(P < 0.002), extent of honeycombing(P < 0.001) and coarseness of fibrosis(P < 0.001) than the paraseptal group. The NSIP group exhibited a significantly higher extent of emphysema(P < 0.05), total lung capacity(P < 0.01) and diffusion capacity(DLCO)(P < 0.05) than the typical UIP group. The typical UIP group exhibited a significantly higher extent of interstitial lung disease, extent of reticular pattern not otherwise specified, extent of ground glass opacity with traction bronchiectasis, extent of honeycombing and coarseness of fibrosis(0.039 > P > 0.000). Although the pulmonary arterial pressure was higher in typical UIP group relative to the NSIP group, the difference was not statistically significant.CONCLUSION: In CPFE patients, paraseptal emphysema is associated more with UIP-HRCT pattern and higher extent of fibrosis than centrilobular emphysema. | Anastasia Oikonomou Paraskevi Mintzopoulou Argyris Tzouvelekis Petros Zezos George Zacharis Anastasios Koutsopoulos Demosthenes Bouros Panos Prassopoulos | 2015 | World Journal of Radiology2015，7，9： | 2 |
| 11 | Circulating MicroRNA in inflammatory bowel disease显示文摘 | Archanioti Paraskevi George Theodoropoulos Ioannis Papaconstantinou Gerassimos Mantzaris Nikolaos Nikiteas Maria Gazouli | 2012 | Journal of Crohn’s and Colitis2012，，9： | 2 |
| 12 | The new 6^(th) edition of the WHO Laboratory Manualfor the Examination and Processing of HumanSemen: is it a step toward better standard operatingprocedure?显示文摘Semen analysis(SA)remains the cornerstone of male infertility evaluation and should ideally be performed by an accredited andrology laboratory or in vitro fertilization(IVF)clinics based on the standards defined by the World Health Organization(WHO)for the Examination and Processing of Human Semen and in accordance with the International Organization for Standardization’s Basic Semen Examination on Specification and Test Methods. | Eric Chung Mohamed Arafa Florence Boitrelle Hussein Kandil Ralf Henkel Ramadan Saleh Rupin Shah Paraskevi Vogiatzi Armand Zini Ashok Agarwal | 2022 | Asian Journal of Andrology2022，24，2： | 2 |
| 13 | Association of Lp-PLA2 with digital reactive hyperemia, coronary flow reserve, carotid atherosclerosis and arterial stiffness in coronary artery disease显示文摘 | Ignatios Ikonomidis Nikolaos N.P. Kadoglou Vlassis Tritakis Ioannis Paraskevaidis Kleanthi Dimas Paraskevi Trivilou Ioannis Papadakis Stavros Tzortzis Helen Triantafyllidi John Parissis Maria Anastasiou-Nana John Lekakis | 2014 | Atherosclerosis2014，，1： | 2 |
| 14 | Quantitative detection of the M204V hepatitis B virus minor variants by amplification refractory mutation system realtime PCR combined with molecular beacon teehnology显示文摘 | Ntziora F Paraskevis D Haida C | 2009 | J Clin Mierobiol2009，47，8： | 1 |
| 15 | Dating the origin and dispersal of hepatitis B virus infection in humans and primates 显示文摘 | Paraskevis D Magiorkinis G Magiorkinis E | 2013 | Hepatology2013，57，3： | 1 |
| 16 | Diffusion tensor and dynamic susceptibility contrast MRI in glioblastoma显示文摘 | Anastasia K. Zikou George A. Alexiou Paraskevi Kosta Ann Goussia Loukas Astrakas Periklis Tsekeris Spyridon Voulgaris Vasiliki Malamou-Mitsi Athanasios P. Kyritsis Maria I. Argyropoulou | 2011 | Clinical Neurology and Neurosurgery2011，，6： | 1 |
| 17 | Effect of temperature and additional carbon sources on phenol degradation by an indigenous soil Pseudomonad显示文摘 | Paraskevi N. Polymenakou Euripides G. Stephanou | 2005 | Biodegradation2005，，5： | 1 |
| 18 | Distal Gastric Cancer and Extensive Surgery: A New Evaluation Method Based on the Study of the Status of Residual Lymph Nodes After Limited Surgery显示文摘 | Dimitrios H. Roukos MD Paraskevi Paraschou MD Matthias Lorenz MD | 2000 | Annals of Surgical Oncology2000，，10： | 1 |
| 19 | Chemiluminometric behaviour of erythromycin and related compounds显示文摘 | Anastassia Mitsana-Papazoglou Argyro Fragaki Paraskevi Chamosfakidi | 2000 | Anal Chim Acta2000，410，12： | 1 |
| 20 | Molecular characterization of occult hep- atitis B cases in Greek blood donors显示文摘 | KATSOULIDOU A PARASKEVIS D MAGIORKI- NIS E | 2009 | J Med Virol2009，81，： | 1 |
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