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| 1 | Modeling height–diameter relationship for Populus euphratica in the Tarim riparian forest ecosystem, Northwest China显示文摘Modeling height–diameter relationships is an important component in estimating and predicting forest development under different forest management scenarios. In this paper, ten widely used candidate height–diameter models were fitted to tree height and diameter at breast height(DBH)data for Populus euphratica Oliv. within a 100 ha permanent plots at Arghan Village in the lower reaches of the Tarim River, Xinjiang Uyghur Autonomous Region of China. Data from 4781 trees were used and split randomly into two sets:75 % of the data were used to estimate model parameters(model calibration), and the remaining data(25 %) were reserved for model validation. All model performances were evaluated and compared by means of multiple model performance criteria such as asymptotic t-statistics of model parameters, standardized residuals against predicted height,root mean square error(RMSE), Akaike's informationcriterion(AIC), mean prediction error(ME) and mean absolute error(MAE). The estimated parameter a for model(6) was not statistically significant at a level of a = 0.05. RMSE and AIC test result for all models showed that exponential models(1),(2),(3) and(4) performed significantly better than others. All ten models had very small MEs and MAEs. Nearly all models underestimated tree heights except for model(6). Comparing the MEs and MAEs of models, model(1) produced smaller MEs(0.0059) and MAEs(1.3754) than other models. To assess the predictive performance of models, we also calculated MEs by dividing the model validation data set into 10-cm DBH classes. This suggested that all models were likely to create higher mean prediction errors for tree DBH classes[20 cm. However, no clear trend was found among models.Model(6) generated significantly smaller mean prediction errors across all tree DBH classes. Considering all the aforementioned criteria, model(1): TH ? 1:3 t a= e1 t b?eàc?DBHT and model(6): TH ? 1:3 t DBH2= ea t b?DBH t c ? DBH2T are recommended as suitable models for describing the height–diameter relationship of P. euphratica. The limitations of other models showing poor performance in predicting tree height are discussed. We provide explanations for these shortcomings. | Tayierjiang Aishan Umüt Halik Florian Betz Philipp Gartner Bernd Cyffka | 2016 | Journal of Forestry Research2016，27，4： | 9 |
| 2 | Gastroenteropancreatic neuroendocrine tumours显示文摘 | Irvin M Modlin Kjell Oberg Daniel C Chung Robert T Jensen Wouter W de Herder Rajesh V Thakker Martyn Caplin Gianfranco Delle Fave Greg A Kaltsas Eric P Krenning Steven F Moss Ola Nilsson Guido Rindi Ramon Salazar Philippe Ruszniewski Anders Sundin | 2008 | Lancet Oncology2008，，1： | 8 |
| 3 | Sporadic versus hereditary gastrinomas of the duodenum and pancreas: Distinct clinico-pathological and epidemiological features显示文摘Gastrinomas are defined as gastrin secreting tumors that are associated with Zollinger-Ellison syndrome (ZES). ZES is characterized by elevated fasting gastrin serum levels, positive secretin stimulation test and clinical symptoms such as recurrent peptic ulcer disease, gastroesophageal re?ux disease and occasional diarrhea. Genetically, nonhereditary (sporadic) gastrinomas are distinguished from hereditary gastrinomas, which are associated with multiple endocrine neoplasia type 1 (MEN1) syndrome. In general, duodenal gastrinomas are small and solitary if they are sporadic and multiple as well as hereditary. The sporadic gastrinomas occur in the duodenum or in the pancreas while the hereditary gastrinomas almost all occur in the duodenum. Our series of 77 sporadic duodenal neuroendocrine tumors (NETs) includes 18 patients (23.4%) with gastrinomas and ZES. Of 535 sporadic NETs in the pancreas collected from the NET archives of the departments of pathology in Zürich, Switzerland, and Kiel, Germany, 24 patients (4.5%) suffered from sporadic pancreatic gastrinomas and ZES. These NETs have to be distinguished fromtumors with immunohistochemical positivity for gastrin but without evidence of ZES. An additional 19 patients suffered from MEN1 and ZES. These patients showed exclusively duodenal gastrinomas, but not pancreatic gastrinomas. The prognosis of sporadic and MEN1- associated duodenal gastrinomas is better than that of pancreatic gastrinomas, since they progress slowly to liver metastasis. In summary, sporadic and MEN1- associated gastrinomas in the duodenum and pancreas show different clinico-pathological and genetic features. The incidence of sporadic duodenal gastrin-producing tumors is increasing, possibly due to optimized diagnostic procedures. In contrast, pancreatic MEN1- associated gastrinomas seem to be extremely rare. A considerable subset of tumors with immunohistochemical expression of gastrin but without evidence of ZES should be designated as functionally inactive NETs expressing gastrin, but not as gastrinomas. | Martin Anlauf Nele Garbrecht Tobias Henopp Anja Schmitt Regina Schlenger Andreas Raffel Markus Krausch Oliver Gimm Claus F Eisenberger Wolfram T Knoefel Henning Dralle Paul Komminoth Philipp U Heitz Aurel Perren Günter Klppel | 2006 | World Journal of Gastroenterology2006，12，34： | 7 |
| 4 | Effects of KRAS, BRAF, NRAS , and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis显示文摘 | Wendy De Roock Bart Claes David Bernasconi Jef De Schutter Bart Biesmans George Fountzilas Konstantine T Kalogeras Vassiliki Kotoula Demetris Papamichael Pierre Laurent-Puig Frédérique Penault-Llorca Philippe Rougier Bruno Vincenzi Daniele Santini Giusepp | 2010 | Lancet Oncology2010，，8： | 6 |
| 5 | FOLFIRI regimen in metastatic pancreatic adenocarcinoma resistant to gemcitabine and platinum-salts显示文摘AIM: To evaluate the efficacy and safety of the FOLFIRI regimen in patients with metastatic pancreatic adenocarcinoma (PAC) after the failure of gemcitabine and platinum salts. METHODS: All consecutive patients with histologically confirmed, metastatic PAC and World Health Organiza-tion performance status (PS) ≤ 2 received FOLFIRI-1 [irinotecan 180 mg/m2 on day 1 and leucovorin 400 mg/m2 followed by 5-fluorouracil (5-FU) 400 mg/m2 bolus, then 5-FU 2400 mg/m2 as a 46-h infusion, biweekly] or FOLFIRI-3 (irinotecan 100 mg/m2 on day 1 and leucovorin 400 mg/m2, then 5-FU 2400 mg/m2 as a 46-h infusion and irinotecan 100 mg/m2 repeated on day 3, biweekly) after failure of gemcitabine and platinum-based chemotherapies as a systematic policy in two institutions between January 2005 and May 2010. Tumor response, time to progression (TTP), overall survival rate (OS) and grade 3-4 toxicities were retrospectively studied. Subgroup analyses were performed to search for prognostic factors. RESULTS: Sixty-three patients (52.4% male, median age 59 years) were analyzed. Among them, 42.9% were PS 0, 38.1% were PS 1 and 19.0% were PS 2. Fifty one patients (81.0%) had liver metastases. Before the FOLFIRI regimen, patients had received 1 line (n = 19), 2 lines (n = 39) or 3 lines (n = 5) of chemotherapy. Median TTP obtained with the line before FOLFIRI was 3.9 mo (95% CI: 3.4-5.3 mo). A total of 480 cycles was completed (median: 6 cycles, range: 1-51 cycles). The main reason for discontinuing FOLFIRI was tumor progression (90.3%). Tumor control was achieved in 25 patients (39.7%) (partial response: n = 5, stable disease: n = 20) with FOLFIRI. Median TTP was 3.0 mo (95% CI: 2.1-3.9 mo) and median OS was 6.6 mo (95% CI: 5.3-8.1 mo). Dose adaptation was required in 36 patients (57.1%). Fifteen patients (23.8%) had grade 3-4 toxicities, mainly hematological (n = 11) or digestive (n = 4). Febrile neutropenia occurred in 3 patients. There was no toxic death. PS 2 was significantly associated with poor TTP [hazard ratio (HR): 16.036, P < 0.0001] and OS (HR: 4.003, P = 0.004). CONCLUSION: The FOLFIRI regimen had an acceptable toxicity and an interesting efficacy in our study, limited to patients in good condition (PS 0-1). | Cindy Neuzillet Olivia Hentic Benot Rousseau Vinciane Rebours Léla Bengrine-Lefèvre Franck Bonnetain Philippe Lévy Eric Raymond Philippe Ruszniewski Christophe Louvet Pascal Hammel | 2012 | World Journal of Gastroenterology2012，18，33： | 3 |
| 6 | Splenic and portal venous obstruction in chronic pancreatitis显示文摘 | Pr. Pierre Bernades André Baetz Philippe Lévy Jacques Belghiti Yves Menu Fran?ois Fékété | 1992 | Digestive Diseases and Sciences1992，，3： | 2 |
| 7 | Reduction in left ventricular messenger RNA for transforming growth factor-β1 attenuates left ventricu fibrosis and improves survival without lowering blood pressure in the hypertensive TGR (mRen2) 27 rat显示文摘 | Pinto Y Philipp T Engler S | 2000 | Hypertension2000，36，5： | 1 |
| 8 | Time-frequency analysis and detection of supersonic inlet buzz显示文摘 | SIMON T SEBASTIEN D PHILIPPE D | 2007 | AIAA Journal2007，45，9： | 1 |
| 9 | 1,3-Diary-4,5,6,7-tetrahydro-2H-isoindole deriv atives:a new series of potent and selective COX-2 inhibitors in which a sulfonyl group is not a structural requisite显示文摘 | Bernard P Charles T Philippe P | 2000 | J Med Chem2000，43，24： | 1 |
| 10 | Dementia patients显示文摘 | Philippe T Fabrice L Pierre-Marie P | 2006 | Journal of Ceriatric Psychiatry2006，21，： | 1 |
| 11 | Deformation induced martensiteand superelasticity in a ^-metastable titanium alloy 显示文摘 | Grosdidier T Philippe M J | 2000 | Materi-als Science and Engineering A2000，291，12： | 1 |
| 12 | General considerations on structure and reactivity of cellulose显示文摘 | Klemm D Philipp B Heinze T | 2004 | Comprehensive Cellulose Chemistry2004，12，3： | 1 |
| 13 | Prevalence and risk factors for adenomas in the ileal pouch and the afferent loop after restorative proctocolectomy for patients with familial adenomatous polyposis显示文摘 | Elise Pommaret Ariane Vienne Jérémie H. Lefevre Philippe Sogni Christian Florent Beno?t Desaint Yann Parc | 2013 | Surgical Endoscopy2013，，10： | 1 |
| 14 | Surface wettability control by nanocoating: The effects on pool boiling heat transfer and nucleation mechanism显示文摘 | Phan H T Caney N Marry Philippe | 2009 | International Journal of Heat and Mass Transfer2009，52，2324： | 1 |
| 15 | Soluble triggering receptor expressed on myeloid cells-1 is released in patients with stable chronic obstructive pulmonary disease 显示文摘 | Markus P Christian T Philipp H | 2007 | Chn Devel Immunol2007，11，55： | 1 |
| 16 | A factor analytical study of perceives organizational hypocrisy显示文摘 | Philippe W T and Koehler W J | 2005 | SAM Advanced Mana gement Journal2005，70，1： | 1 |
| 17 | A new pumpless extracorporeal in terventional lung assist in critical hypoxemia/hypercapnia 显示文摘 | Bein T Weber F Philipp A | 2006 | Crit Care Med2006，34，5： | 1 |
| 18 | 显示文摘 | Pinto YM Pinto-Sietsma SJ Philipp T | 2000 | Hypertension2000，36，5： | 1 |
| 19 | Spinal cord herniation: a misdiagnosed and treatable cause of thoracic myelopathy 显示文摘 | Fahed Z Lanrent T Philippe B | 2010 | European radiology2010，152，： | 1 |
| 20 | Evidence of somatic mosaicism for a MECP2 mutation in females with Rett syndrome:diagnostic implications显示文摘 | Bourdon V Philippe C Bienvenu T | | 0，，： | 1 |
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