|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Pharmacognostic study and anti-inflammatory activity of Callistemon lanceolatus leaf显示文摘Objective:To study detail pharmacognosy and anti-inflammatory activity of Callistemon lanceolatus(C.lanceolatus) leaf.Methods:Leaf sample was studied by organoleptic, macroscopical,microscopical,phytochemical and other WHO recommended methods for standardizations.The methanolic leaf extract of the plant was also screened for antiinflammatory activity on carrageenan-induced paw edema in rat at doses of 200 and 400 mg/kg, orally.The detail pharmacognostic study of the C.lanceolatus leaf was carried out to lay down the standards which could be useful in future experimental studies.Results:C.lanceolatus methanolic leaf extract showed significant(P<0.0S) anti-inflammatory activity at doses of 200 mg/kg and 400 mg/kg.This significant anti-inflammatory of C.lanceolatus methanolic leaf extract at the dose of 400 mg/kg was comparable with diclofenac sodium.Conchuioiis:The pharmacognostic profile of the C.lanceolatus leaf is helpful in standardization for quality,purity and sample identification.The methanolic extract at a dose of 400 mg/kg shows a significant activity in comparison with the standard drug diclofenac sodium(50 mg/kg). | Kumar S Kumar V Prakash OM | 2011 | Asian Pacific Journal of Tropical Biomedicine2011，1，3： | 10 |
| 2 | Characterization of chickpea germplasm conserved in the Indian National Genebank and development of a core set using qualitative and quantitative trait data显示文摘Chickpea is the third most important pulse crop as a source of dietary protein. Ever-increasing demand in Asian countries calls for breeding superior desi-type varieties, in turn necessitating the availability of characterized germplasm to breeders. The Indian National Genebank,located at the National Bureau of Plant Genetic Resources, New Delhi, conserves 14,651 accessions of chickpea. The entire set was characterized in a single large-scale experiment.High variation was observed for eight quantitative and 12 qualitative agro-morphological traits. Allelic richness procedure was employed to assemble a core set comprising 1103 accessions, 70.0% of which were of Indian origin. Comparable values of total variation explained by the first three principal components in the entire collection(51.1%) and the core(52.4%)together with conservation of nine pairwise r values among quantitative traits in the core collection and a coincidence rate around 99.7% indicated that the chickpea core was indeed an excellent representation of the entire chickpea collection in the National Genebank. The chickpea core exhibited greater diversity than the entire collection in agro-morphological traits, as assessed by higher variance and Shannon–Weaver diversity indices, indicating that the chickpea core maximized the phenotypic diversity available in the Indian chickpea germplasm. The chickpea core, comprising mainly indigenous desi genotypes, is expected to be an excellent resource for chickpea breeders. Information on the chickpea core can be accessed at http://gffzz905398e276204fc7hbcf5qofpo0po659k.ffgz.tsg.suse.edu.cn/pgrportal. | Sunil Archak Rishi K.Tyagi P.N.Harer L.B.Mahase Neeta Singh Om P.Dahiya M.Abdul Nizar Mohar Singh Vrushali Tilekar Vikas Kumar Manoranjan Dutta Narendra P.Singh Kailash C.Bansal | 2016 | The Crop Journal2016，4，5： | 7 |
| 3 | Role of angiotensin converting enzyme and angiotensinogen gene polymorphisms in angiotensin converting enzyme inhibitor-mediated antiproteinuric action in type 2 diabetic nephropathy patients显示文摘AIM To investigate the role of genetic variants of angiotensin converting enzyme(ACE) and angiotensinogen(AGT) genes in the antiproteinuric efficacy of ACE inhibitor therapy in diabetic nephropathy(DN) patients.METHODS In the present study, 270 type 2 diabetes mellitus patients with nephropathy were enrolled and treated with ACE inhibitor(ramipril) and followed at 6 mo for renal function and albumin excretion by estimating serum creatinine, end stage renal disease, and albumin/creatinine ratio(ACR) in urine. Genotyping of ACE I/D and AGT M235 T polymorphisms were performed by using primer specific polymerase chain reaction(PCR) and PCR-RFLP techniques, respectively. RESULTS Forty-eight percent of DN patients(responders) benefited with respect to proteinuria from ACE inhibitor therapy at 6 mo follow-up. A significant reduction in ACR was observed after 6 mo treatment with ACE inhibitor irrespective of whether DN patients were micro-albuminuric(≥ 30 and < 300 mg/g creatinine) or macro-albuminuric(≥ 300 mg/g creatinine) at the time of enrollment. However, macro-albuminuric patients(55%) showed better response to therapy. A reduction in urinary ACR was found independent of genotypes of ACE I/D and AGT M235 T polymorphisms although macro-albuminuric patients having TT genotype showed statistically insignificant increased response(72%). CONCLUSION ACE inhibitor therapy reduced urinary ACR by ≥ 30% in 50% of DN patients and the response is independent of ACE I/D and AGT M235 T polymorphisms. | Neerja Aggarwal Pawan Kumar Kare Parul Varshney Om Prakash Kalra Sri Venkata Madhu Basu Dev Banerjee Anil Yadav Alpana Raizada Ashok Kumar Tripathi | 2017 | World Journal of Diabetes2017，8，3： | 4 |
| 4 | Antidiabetic,hypolipidemic and histopathological analysis of Dillenia indica (L.) leaves extract on alloxan induced diabetic rats显示文摘Objective:To investigate antidiabetic,hypolipidemic histopathological analysis of Dillenia indica(D.indica) methanolic leaves(DIME) extract in alloxan induced diabetic rat by administering oral doses(250 and 500 mg/kg body weight).Methods:Blood glucose levels were measured using blood glucose test strips with elegance glucometer on weekly intervals till the end of study(i.e.3 weeks).Other parameters e.g.liver profile,renal profile and total lipid levels were determined in normal and alloxan induced diabetic rats after oral administration of the extract for 21 days.Histopathological changes in diabetic rat organs(pancreas,liver and kidney) were also observed after extract treatment Results:Daily oral administration DIME(250 and 500 mg/kg body weight) and glibenclamide(10 mg/kg) showed beneficial effects on blood glucose level (P<0.001) as well as improving kidney,liver functions and hyperlipidaemia due to diabetes. The extract treatment also showed to enhanced serum insulin level and body weight of diabetic rats as compared to diabetic control group.Furthermore,the extract has a favorable effect on the histopathological changes of the pancreas,liver and kidney in alloxan induced diabetes. Conclusions:D.indica possess antidiabetic property as well improve body weight,liver profile, renal profile and total lipid levels.DIME has also favorable effect to inhibit the histopathological changes of the pancreas and kidney in alloxan induced diabetes. | Sunil Kumar Vipin Kumar Om Prakash | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，5： | 4 |
| 5 | 含笑属植物所含化学成分与其生物活性的综述(英文)显示文摘属木兰科的含笑属植物大约有80多个种类,它们大都分布在南亚国家。这些植物被当地人用于治疗各种疾病,如发烧、绞痛、麻风病、眼疾、炎症以及解蝎子毒。从9种含笑属植物中分离出94种化合物,例如倍半萜烯、类固醇、黄酮类、阿扑啡类、苯酚、酯类、生物碱和苯环型化合物等,它们具有抗菌、抗癌以及抗疟原虫活性。本文详细地论述了含笑属植物所含化学成分的生物及化学性能。 | Dinesh Kumar Sunil Kumar Seema Taprial Deepak Kashyap Ajay Kumar Om Prakash | 2012 | 中西医结合学报2012，10，12： | 4 |
| 6 | Antidiabetic and hypolipidemic activities of Kigelia pinnata flowers extract in streptozotocin induced diabetic rats显示文摘Objective:To evaluate antidiabetic and hypolipidemic activities of Kigelia pinnata rnethanolic(lowers extract in slreplozolocin(STZ) induced diabetic W islar rat.Methods.Rats were made diabetic by a single dose of STZ at 60 mg/kg body weight i.p.The blood glucose level was checked before and 72 h after STZ injection to confirm the development ot diabetes.The flower extract and glibenclamide were administered orally at the doses of 250 and 500 mg/kg body weight for 21 days.Results:Daily oral treatment with the extract and standard drug for 21 days significantly reduced blood glucose,serum cholesterol and triglycerides levels.High density lipoprotein-cholesterol level was found to be improved(P<0.01) as compared to diabetic control group.Conclusions:It is concluded that Kigellia pinnata flowers extract have significant antidiabetic and hypolipidemic effect. | Kumar S Kumar V Prakash OM | 2012 | Asian Pacific Journal of Tropical Biomedicine2012，2，7： | 4 |
| 7 | Antidiabetic and anti-lipemic effects of Cassia siamea leaves extract in streptozotocin induced diabetic rats显示文摘Objective:To investigate the antidiabetic and anti-lipemic effects of Cassia siamea methanolic leaves extract.Methods:The antidiabetic study was performed by measuring blood glucose level with elegance glucometer at weekly intervals i.e.0,7,14 and 21 in normal and streptozotocin induced diabetic rats.Total cholesterol,triglyceride and HDL-cholesterol were determined in normal and streptozotocin induces diabetic rats by autoanalyser.Glibenclamide was used as a reference drug at a dose of 10 mg/kg.Results:After the oral administration of extracts at doses of 250 mg/kg and 500 mg/kg for three weeks,blood glucose levels and body weights were significantly improved(P<0.01).Daily oral treatment with the extract also resulted in significantly reduction of serum cholesterol and triglycerides.HDL-cholesterol level was found to be improved to(P<0.01).Conclusions:The Cassia siamea leaf extract is useful in controlling blood glucose level as well as improving lipid metabolism and body weight in rats with induced diabetes. | S Kumar V Kumar Om Prakash | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，11： | 3 |
| 8 | Primary access-related complications in laparoscopic cholecystectomy via the closed technique: experience of a single surgical team over more than 15 years显示文摘 | Prakash Kumar Sasmal Om Tantia Mayank Jain Shashi Khanna Bimalendu Sen | 2009 | Surgical Endoscopy2009，，11： | 3 |
| 9 | An improved and secure multiserver authentication scheme based on biometrics and smartcard显示文摘 | Ashish Kumar Hari Om | 2018 | Digital Communications and Networks2018，4，1： | 3 |
| 10 | Effect of potassium on soil conservation and productivity of maize/cowpea based crop rotations in the north-west Indian Himalayas显示文摘Plots under conservation tillage may require higher amount of potassium(K) application for augmenting productivity due to its stratification in upper soil layers, thereby reducing K supplying capacity in a medium or long-term period. To test this hypothesis, a field experiment was performed in 2002-2003 and 2006-2007 to study the effect of K and several crop rotations on yield, water productivity, carbon sequestration, grain quality, soil K status and economic benefits derived in maize(Zea mays L)/cowpea(Vigna sinensis L.) based cropping system under minimum tillage(MT). All crops recorded higher grain yield with a higher dose of K(120 kg K2 O ha-1) than recommended K(40 kg K2 O ha-1). The five years' average yield data showed that higher K application(120 kg K2 O ha-1) produced 16.4%(P<0.05)more maize equivalent yield. Cowpea based rotation yielded 14.2%(P<0.05) higher production than maize based rotation. The maximum enhancement was found in cowpea-mustard rotation. Relationship between yield and sustainable indices revealed that only agronomic efficiency of fertilizer input was significantly correlated with yield. Similarly, higherdoses of K application not only increased the water use efficiency(WUE) of all crops, but also reduced runoff and soil loss by 16.5% and 15.8% under maize and 23.3% and 19.7% under cowpea cover, respectively. This study also revealed that on an average 16.5% of left over carbon input contributed to soil organic carbon(SOC). Here, cowpea based rotation with the higher K application increased carbon sequestration in soil. Potassium fertilization also significantly improved the nutritional value of harvested grain by increasing the protein content for maize(by 9.5%) and cowpea(by 10.6%). The oil content in mustard increased by 5.0% and 6.0% after maize and cowpea, respectively. Net return also increased with the application of the higher K than recommended K and the trend was similar to yield. Hence, the present study demonstrated the potential yield and profit gains along with resource conservation in the Indian Himalayas due to annual additions of higher amount of K than the recommended dose. The impact of high K application was maximum in the cowpea-mustard rotation. | Birendra Nath GHOSH Om Pal Singh KHOLA Ranjan BHATTACHARYYA Kuldeep Singh DADHWAL Prasant Kumar MISHRA | 2016 | Journal of Mountain Science2016，13，4： | 2 |
| 11 | Effect of K2O addition on crystallization and microstructural behaviour of the strontium titanate-borosilicate glass-ceramic system显示文摘 | THAKUR O P KUMAR Devendra PARKASH Om etal | 1995 | Mater Lett1995，23，： | 2 |
| 12 | BISAP评分与Ranson评分和CT严重指数预测印度急性胰腺炎患者并发症发生率和病死率的比较研究显示文摘目的:本研究通过印度中东部地区一家三甲医院,前瞻性评估急性胰腺炎严重度床边指数(BISAP)评分预测急性胰腺炎患者病死率及疾病进展中间指标的准确性,从而为贫困人群提供一个经济、有效的预后预测方法。方法:2012-2014年间我们中心连续收治的119例急性胰腺炎患者纳入研究。起病24 h内对所有病例进行BISAP评分,同时也进行Ranson评分和CT严重指数(CTSI)评估。采用趋势和判别分析来对这三种评分系统对病死率的预测价值进行评价。通过受试者操作特征(ROC)曲线评估这三种评分系统对急性胰腺炎患者病死率及疾病进展中间指标(器官衰竭和胰腺坏死)的预测情况。结果:119例入组病例中42例(35.2%)出现器官衰竭,定义为重症急性胰腺炎,47例(39.5%)发生胰腺坏死,12例(10.1%)死亡。BISAP评分预测重症急性胰腺炎、胰腺坏死和死亡的曲线下面积(AUC)分别为0.962、0.934和0.846。Ranson评分预测重症急性胰腺炎(AUC 0.956)和死亡(AUC 0.841)的准确性稍低于BISAP评分。CTSI在预测胰腺坏死方面的准确性最高,AUC为0.958。以≥3分作为截点,BISAP评分预测病死率的敏感性和特异性分别为100%和69.2%。结论:BISAP评分简单实用,在急性胰腺炎起病24 h内即可鉴别出高危死亡风险及高危疾病进展风险的患者。这种风险分层方法可用以提高临床诊治,并有助于临床研究中的病例入组。 | Jitin Yadav Sanjay Kumar Yadav Satish Kumar Ranjan George Baxla Dipendra Kumar Sinha Pankaj Bodra Ram Chandra Besra Babu Mani Baski Om Prakash Abhinav Anand | 2016 | Gastroenterology Report2016，4，3： | 2 |
| 13 | Bioconversion of lignocellulosic biomass: biochemical and molecular perspectives显示文摘 | Raj Kumar Sompal Singh Om V. Singh | 2008 | Journal of Industrial Microbiology & Biotechnology2008，，5： | 1 |
| 14 | Allelopathic response of Phalaris minor to crop and weed plants in rice-wheat system显示文摘 | Om H Dhiman S D Kumar S | 2002 | Crop Protection2002，21，9： | 1 |
| 15 | Preparation and characterization of barium stannate BaSnO3显示文摘 | SHAIL Upadhyay Om Parkash Devendra Kumar | 1997 | Journal of Materials Science Letters1997，，16： | 1 |
| 16 | Integrating AI Based DGA Fault Diagnosis Using Dempster Shafer Theory显示文摘 | BHALLA Deepika BANSAL Raj Kumar GUPTA Hari Om | 2013 | International Journal of Electrical Power&Energy Systems2013，48，： | 1 |
| 17 | Abrin induce oxidative stress mediated DNA damage in human leukemic cells and its reversal by N-acetylcysteine显示文摘 | Utsab Deb Om Kumar PV Lakshmana Rao | 2008 | Toxical In Vitro2008，22，8： | 1 |
| 18 | Austin Moor Prosthetic Replacement in Fracture Neck of Femur in Elderly Patient using minimally invasive approach显示文摘 | Om Prakash Kumar | 2012 | Indian medical journal2012，106，2： | 1 |
| 19 | Structural and relaxor behavior of (Ba 1? x La x )(Ti 0.85 Sn 0.15 )O 3 ceramics obtained by solid state reaction显示文摘 | Sindhu Singh Prabhakar Singh Om Parkash Devendra Kumar | 2010 | Journal of Alloys and Compounds2010，，1： | 1 |
| 20 | Historical Review and Recent Trends in Solar Drying Systems显示文摘 | Om Prakash Anil Kumar | 2013 | International Journal of Green Energy2013，，7： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员