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4篇 您的检索式：作者名="Nicolas Isambert"

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		题名	作者	年代	出处	被引量
	1	Degarelix as a new antiangiogenic agent for metastatic colon cancer?显示文摘Recently,follicle stimulating hormone receptor was found to be selectively expressed by endothelial cells on tumor-associated blood vessels in a wide range of human cancers.In this context,we hypothesized that degarelix,a new gonadotropin-releasing hormone receptor antagonist developed for patients with prostate cancer,may have antiangiogenic effects via its capacity to block follicle stimulating hormone(FSH)production. We report the case of a patient with metastatic colon cancer exhibiting tumor progression after failure of all conventional chemotherapeutic regimens.The addition of degarelix to the last chemotherapeutic regimen was proposed as compassionate treatment.Degarelix induced a rapid decrease in FSH level.This treatment induced radiological stabilization and carcinoembryonic antigen stabilization during 1 year.Contrast-enhanced ultrasonography demonstrated reduction of tumor vas-clature.This case represents the first report of an antitumoral effect of degarelix in metastatic colon cancer and suggests an antiangiogenic property of this drug.	Francois Ghiringhelli Nicolas Isambert Sylvain Ladoire	2013	World Journal of Gastroenterology2013，19，5：	2
	2	Comparison of doxorubicin and weekly paclitaxel efficacy in metastatic angiosarcomas显示文摘	Antoine Italiano Angela Cioffi Nicolas Penel Matteo Giaj Levra Corinne Delcambre Elsa Kalbacher Christine Chevreau Fran?ois Bertucci Nicolas Isambert Jean‐Yves Blay Binh Bui Cristina Antonescu David R. D’Adamo Robert G. Maki Mary Louise Keohan	2011	Cancer2011，，13：	1
	3	Sorafenib in patients with progressive epithelioid hemangioendothelioma显示文摘	Christine Chevreau Axel Le Cesne Isabelle Ray‐Coquard Antoine Italiano Angela Cioffi Nicolas Isambert Yves Marie Robin Charles Fournier Stéphanie Clisant Loic Chaigneau Jacques‐Olivier Bay Emmanuelle Bompas Eric Gauthier Jean Y. Blay Nicolas Penel	2013	Cancer2013，，14：	1
	4	Randomized Multicenter and Stratified Phase II Study of Gemcitabine Alone Versus Gemcitabine and Docetaxel in Patients with Metastatic or Relapsed Leiomyosarcomas: A Fédération Nationale des Centres de Lutte Contre le Cancer (FNCLCC) French Sarcoma Group 显示文摘	Patricia Pautier Anne Floquet Nicolas Penel Sophie Piperno-Neumann Nicolas Isambert Annie Rey Emmanuelle Bompas Angela Cioffi Corinne Delcambre Didier Cupissol Fran?oise Collin Jean-Yves Blay Marta Jimenez Florence Duffaud	2012	The Oncologist2012，，9：	1

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