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44篇 您的检索式：作者名="Isambert"

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	题名	作者	年代	出处	被引量
1	Degarelix as a new antiangiogenic agent for metastatic colon cancer?显示文摘Recently,follicle stimulating hormone receptor was found to be selectively expressed by endothelial cells on tumor-associated blood vessels in a wide range of human cancers.In this context,we hypothesized that degarelix,a new gonadotropin-releasing hormone receptor antagonist developed for patients with prostate cancer,may have antiangiogenic effects via its capacity to block follicle stimulating hormone(FSH)production. We report the case of a patient with metastatic colon cancer exhibiting tumor progression after failure of all conventional chemotherapeutic regimens.The addition of degarelix to the last chemotherapeutic regimen was proposed as compassionate treatment.Degarelix induced a rapid decrease in FSH level.This treatment induced radiological stabilization and carcinoembryonic antigen stabilization during 1 year.Contrast-enhanced ultrasonography demonstrated reduction of tumor vas-clature.This case represents the first report of an antitumoral effect of degarelix in metastatic colon cancer and suggests an antiangiogenic property of this drug.	Francois Ghiringhelli Nicolas Isambert Sylvain Ladoire	2013	World Journal of Gastroenterology2013，19，5：	2
2	Commercial applications of microalgae显示文摘	Pauline Spolaore Claire Joannis-Cassan Elie Duran Arsène Isambert	2006	Journal of Bioscience and Bioengineering2006，，2：	2
3	A pre-clinical assessment of an atlas-based automatic segmentation tool for the head and neck 显示文摘	Sims R Isambert A Gregoire V	2009	Radiother Oueol2009，93，3：	1
4	Novel tubulin-tar- geting agents: anticancer activity and pharmacologic profile of epothilones and related analogues 显示文摘	FUMOLEAU P COUDERT B ISAMBERT N	2007	Ann Oncol2007，18，：	1
5	Present and future of theimage guided radiotherapy (IGRT) and its applications in lung cancer treatment显示文摘	LEFKOPOULOS D FERREIRA I ISAMBERT A etal	2007	Cancer Radiother2007，11，12：	1
6	Novel tubulin-targeting agents:anticancer activity and pharmacologic profile of epothilones and related analogues显示文摘	Fumoleau P Coudert B Isambert N	2007	Ann Oncol2007，18，5：	1
7	A phantom study of the accuracy of CT,MR and PET image registrations with a block matching-based algorithm显示文摘	Isambert A Bonniaud C Lavielle F	2008	Cancer Radiother2008，12，8：	1
8	Phase I dose-escalation study ofintravenous aflibercept in combination with docetaxel in patientswith advanced solid tumors 显示文摘	Isambert N Freyer G Zanetta S	2012	Clin Cancer Res2012，18，6：	1
9	Relationship of the presence of a non-calcareous clay-loam horizon to DEM attributes in a gently sloping area显示文摘	King D Bourennane H Isambert M	1999	Geoderma1999，89，：	1
10	Present and future of the image guided radiotherapy (IGRT) and its applications in lung cancer treatment显示文摘	Lefkopoulos D Ferreira I Isambert A	2007	Cancer Radiother2007，11，2：	1
11	Novel tubu- lin targeting agents: anticancer activity and pharmacologic profile of epothilones and related analogues 显示文摘	Fumoleau P Coudert B Isambert N	2007	Ann Oneol2007，18，5：	1
12	Electrostimulation of anterior sacral nerve roots in spinal cord injury patients:evaluation of the 1st 25 cases显示文摘	Colombel P Egon G Isambert JL	1992	Prog Urol1992，2，1：	1
13	Comparison of doxorubicin and weekly paclitaxel efficacy in metastatic angiosarcomas显示文摘	Antoine Italiano Angela Cioffi Nicolas Penel Matteo Giaj Levra Corinne Delcambre Elsa Kalbacher Christine Chevreau Fran?ois Bertucci Nicolas Isambert Jean‐Yves Blay Binh Bui Cristina Antonescu David R. D’Adamo Robert G. Maki Mary Louise Keohan	2011	Cancer2011，，13：	1
14	Sorafenib in patients with progressive epithelioid hemangioendothelioma显示文摘	Christine Chevreau Axel Le Cesne Isabelle Ray‐Coquard Antoine Italiano Angela Cioffi Nicolas Isambert Yves Marie Robin Charles Fournier Stéphanie Clisant Loic Chaigneau Jacques‐Olivier Bay Emmanuelle Bompas Eric Gauthier Jean Y. Blay Nicolas Penel	2013	Cancer2013，，14：	1
15	Phase I study of OM- 174, a lipid A analogue, with assessment of immunological response, in patients with refractory solid tumors 显示文摘	Isambert N Fumoleau P Paul C	2013	BMC Can- cer2013，13，：	1
16	Trends in incidence and management of gallbladder carcinoma:a population-based study in France显示文摘	Manfredi S Benhamiche AM Isambert N		0，，：	1
17	Relationship of the presence of non calcareous clay loam horizon to DEM attributes in a gently sloping area 显示文摘	King D Bourennane H Isambert M	1999	Geoderma1999，89，5：	1
18	Trends in incidence and management of gallbladder carcinoma: s populationbased study in France显示文摘	Manfredi S Benhamiche AM Isambert N	2000	Cancer2000，89，4：	1
19	Pediatric single-lumen can-nula venovenous extracorporeal membrane oxygenation:a French center experience显示文摘	Leger PL Guilbert J Isambert S	2013	Artif Organs2013，37，1：	1
20	Relationship of the presence of a non-calcareous clay-loam horizon to DEM attributes in a gently sloping area显示文摘	King D Bourennane H Isambert M	1999	Geoderma1999，89，12：	1

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