| 1 | Effect of colouring green stage zirconia on the adhesion of veneering ceramics with different thermal expansion coefficients显示文摘This study evaluated the adhesion of zirconia core ceramics with their corresponding veneering ceramics, having different thermal expansion coefficients(TECs), when zirconia ceramics were coloured at green stage. Zirconia blocks(N5240; 6 mm37 mm37 mm) were manufactured from two materials namely, ICE Zirconia(Group 1) and Prettau Zirconia(Group 2). In their green stage, they were randomly divided into two groups. Half of the specimens were coloured with colouring liquid(shade A2). Three different veneering ceramics with different TEC(ICE Ceramic, GC Initial Zr and IPS e.max Ceram) were fired on both coloured and non-coloured zirconia cores. Specimens of high noble alloys(Esteticor Plus) veneered with ceramic(VM 13)(n516) acted as the control group. Core–veneer interface of the specimens were subjected to shear force in the Universal Testing Machine(0.5 mm?min21). Neither the zirconia core material(P50.318) nor colouring(P50.188) significantly affected the results(three-way analysis of variance, Tukey's test). But the results were significantly affected by the veneering ceramic(P50.000). Control group exhibited significantly higher mean bond strength values(45.768) MPa than all other tested groups((27.164.1)2(39.764.7) and(27.465.6)2(35.964.7) MPa with and without colouring, respectively)(P,0.001). While in zirconia–veneer test groups, predominantly mixed type of failures were observed with the veneering ceramic covering,1/3 of the substrate surface, in the metal–ceramic group, veneering ceramic was left adhered.1/3 of the metal surface. Colouring zirconia did not impair adhesion of veneering ceramic, but veneering ceramic had a significant influence on the core–veneer adhesion. Metal–ceramic adhesion was more reliable than all zirconia–veneer ceramics tested. | Guliz Aktas Erdal Sahin Pekka Vallittu Mutlu zcan Lippo Lassila | 2013 | International Journal of Oral Science2013，5，4： | 2 |
| 8 | The in-vivo assessment of Turkish propolis and its nano form on testicular damage induced by cisplatin显示文摘Objective: Chemotherapeutic drugs, such as cisplatin(CP), which are associated with oxidative stress and apoptosis, may adversely affect the reproductive system. This study tests whether administration of propolis and nano-propolis(NP) can alleviate oxidative stress and apoptosis in rats with testicular damage induced by CP.Methods: In this study, polymeric nanoparticles including propolis were synthesized with a green sonication method and characterized using Fourier transform-infrared spectroscopy, Brunauer-EmmettTeller, and wet scanning transmission electron microscopy techniques. In total, 56 rats were divided into the following seven groups: control, CP, propolis, NP-10, CP + propolis, CP + NP-10, and CP + NP-30.Propolis(100 mg/kg), NP-10(10 mg/kg), and NP-30(30 mg/kg) treatments were administered by gavage daily for 21 d, and CP(3 mg/kg) was administered intraperitoneally in a single dose. After the experiment,oxidative stress parameters, namely, malondialdehyde(MDA), glutathione(GSH), glutathione peroxidase(GPx), and catalase(CAT), and apoptotic pathways including B cell leukemia/lymphoma-2 protein(Bcl-2)and Bcl-2-associated X protein(Bax) were measured in testicular tissues. Furthermore, sperm quality and weights of the testis, epididymis, right cauda epididymis, seminal vesicles and prostate were evaluated.Results: Propolis and NP(especially NP-30) were able to preserve oxidative balance(decreased MDA levels and increased GSH, CAT, and GPx activities) and activate apoptotic pathways(decreased Bax and increased Bcl-2) in the testes of CP-treated rats. Sperm motility in the control, CP, and CP + NP-30 groups were 60%, 48.75%, and 78%, respectively(P<0.001). Especially, NP-30 application completely corrected the deterioration in sperm features induced by CP.Conclusion: The results show that propolis and NP treatments mitigated the side effects of CP on spermatogenic activity, antioxidant situation, and apoptosis in rats. | Pinar Tatli Seven Ismail Seven Selcan Karakus Seda Iflazoglu Mutlu Seyma Ozer Kaya Gozde Arkali Merve Ilgar Ezgi Tan Yesim Muge Sahin Deniz Ismik Ayben Kilislioglu | 2021 | Journal of Integrative Medicine2021，19，5： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员