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| 1 | Comparison of early enteral nutrition in severe acute pancreatitis with prebiotic fiber supplementation versus standard enteral solution:A prospective randomized double-blind study显示文摘AIM: To compare the benefi cial effects of early enteral nutrition (EN) with prebiotic fiber supplementation in patients with severe acute pancreatitis (AP).METHODS: Thirty consecutive patients with severe AP, who required stoppage of oral feeding for 48 h, were randomly assigned to nasojejunal EN with or without prebiotics. APACHE Ⅱ score, Balthazar’s CT score and CRP were assessed daily during the study period.RESULTS: The median duration of hospital stay was shorter in the study group [10 ± 4 (8-14) d vs 15 ± 6 (7-26) d] (P < 0.05). The median value of days in intensive care unit was also similar in both groups [6 ± 2 (5-8) d vs 6 ± 2 (5-7) d]. The median duration of EN was 8 ± 4 (6-12) d vs 10 ± 4 (6-13) d in the study and control groups, respectively (P > 0.05). Deaths occurred in 6 patients (20%), 2 in the study group and 4 in the control group. The mean duration of APACHE Ⅱ normalization (APACHE Ⅱ score < 8) was shorter in the study group than in the control group (4 ± 2 d vs 6.5 ± 3 d, P < 0.05). The mean duration of CRP normalization was also shorter in the study group than in the control group (7 ± 2 d vs 10 ± 3 d, P < 0.05).CONCLUSION: Nasojejunal EN with prebiotic fiber supplementation in severe AP improves hospital stay, duration nutrition therapy, acute phase response and overall complications compared to standard EN therapy. | Tarkan Karakan Meltem Ergun Ibrahim Dogan Mehmet Cindoruk Selahattin Unal | 2007 | World Journal of Gastroenterology2007，13，19： | 50 |
| 2 | A review on machinability of carbon fiber reinforced polymer(CFRP)and glass fiber reinforced polymer(GFRP)composite materials显示文摘Fiber reinforced polymer(FRP) composite materials are heterogeneous and anisotropic materials that do not exhibit plastic deformation. They have been used in a wide range of contemporary applications particularly in space and aviation,automotive,maritime and manufacturing of sports equipment. Carbon fiber reinforced polymer(CFRP) and glass fiber reinforced polymer(GFRP) composite materials,among other fiber reinforced materials,have been increasingly replacing conventional materials with their excellent strength and low specific weight properties. Their manufacturability in varying combinations with customized strength properties,also their high fatigue,toughness and high temperature wear and oxidation resistance capabilities render these materials an excellent choice in engineering applications.In the present review study,a literature survey was conducted on the machinability properties and related approaches for CFRP and GFRP composite materials. As in the machining of all anisotropic and heterogeneous materials,failure mechanisms were also reported in the machining of CFRP and GFRP materials with both conventional and modern manufacturing methods and the results of these studies were obtained by use of variance analysis(ANOVA),artificial neural networks(ANN) model,fuzzy inference system(FIS),harmony search(HS) algorithm,genetic algorithm(GA),Taguchi's optimization technique,multi-criteria optimization,analytical modeling,stress analysis,finite elements method(FEM),data analysis,and linear regression technique. Failure mechanisms and surface quality is discussed with the help of optical and scanning electron microscopy,and profilometry. ANOVA,GA,FEM,etc. are used to analyze and generate predictive models. | Meltem Altin Karatas Hasan Gokkaya | 2018 | Defence Technology(防务技术)2018，14，4： | 31 |
| 3 | Gallbladder function and dynamics of bile flow in asymptomatic gallstone disease显示文摘AIM:To investigate the effects of gallbladder stones on motor functions of the gallbladder and the dynamics of bile flow in asymptomatic gallstone disease.METHODS:Quantitative hepatobiliary scintigraphy was performed to detect the parameters of gallbladder motor function [gallbladder ejection fraction(GBEF),gallbladder visualization time(GBVT),gallbladder time to peak activity(GBTmax),gallbladder half emptying time(GBT1/2),and transit time of bile to duodenum(TTBD)] in 24 patients with asymptomatic cholelithiasis who were diagnosed incidentally during routine abdominal ultrasonographic examination and 20 healthy subjects with normal gallbladder.RESULTS:Even though there was no significant difference in the clinical and laboratory parameters between the patient and control groups,all parameters of gallbladder function except TTBD were found to differ significantly between the two groups.GBEF in the patient group was decreased(P=0.000) and GBVT,GBTmax,GBT1/2 in the patient group were longer(P=0.000,P=0.015,P=0.001,respectively).CONCLUSION:Our results showed that even if there were not any clinical and laboratory findings,gallbladder filling and emptying could be impaired in patients with gallstone disease. | Sevim Süreyya eri Feride Meltem zbek Celal eri Bahattin Baykal Hasan Erol Eroglu Zeynep Baykal Mustafa Yildiz Semahat Saglam Ahmet Yesildag | 2009 | World Journal of Gastroenterology2009，15，22： | 8 |
| 4 | Primary glomerular diseases in the elderly显示文摘Primary glomerular diseases in the elderly population are a frustrating topic due to difficulties in both the diagnosis and decision making about treatment. The most frequent type of primary glomerular disease in elderly is membranous nephropathy; while its counterpart in younger population is Ig A nephropathy. The most frequent cause of nephrotic syndrome in the elderly is also membranous nephropathy. Pauci-immune crescentic glomerulonephritis(GN) rate increases both in elderly and very elderly population. Pauci-immune crescentic GNs should be regarded as urgencies in elderly patients as in their younger counterparts due to potential for causing end-stage renal disease in case of delayed diagnosis and treatment, and also causing mortality due to alveolar hemorrhage in patients with pulmonary involvement. Renal biopsy is the inevitable diagnostic method in the elderly as in all other age groups. Renal biopsy prevents unnecessary treatments and provides prognostic data. So advanced age should not be the sole contraindication for renal biopsy. The course of primary glomerular diseases may differ in the elderly population. Acute kidney injury is more frequent in the course and renal functions may be worse at presentation. These patients are more prone to be hypertensive. The decision about adding immune suppressive therapies to conservative methods should be made considering many factors like co-morbidities, drug side effects and potential drug interactions, risk of infection, patient preference, life expectancy and renal functions at the time of diagnosis. | Abdullah Sumnu Meltem Gursu Savas Ozturk | 2015 | World Journal of Nephrology2015，4，2： | 6 |
| 5 | 匹克威克综合征和阻塞性睡眠呼吸暂停综合征相关性假性脑瘤(英文)显示文摘目的:报告1例男性患者合并有匹克威克综合征和阻塞性睡眠呼吸暂停(OSA),其临床表现为假性脑瘤和视力下降。方法:病例报告。结果:患者,男,54岁,过度肥胖,诉双眼视力渐降3mo,检查示:视力:右眼20/200,左眼20/400,左眼合并色觉异常,眼底镜示双视乳头水肿和视盘旁出血,左眼合并黄斑部渗出。体格检查和实验室检查符合阻塞性睡眠呼吸暂停与匹克威克综合征诊断。腰椎穿刺:开放压350mmHg,脑部扫描正常。诊断:OSA和匹克威克综合征相关性假性脑瘤。眼底表现和视力随采血治疗、血压控制、体重控制及双层正压通气治疗而改善。结论:对于患有假性脑瘤的患者,必须对阻塞性睡眠呼吸暂停与匹克威克综合征有所警惕。 | Ozlem Barut Selver Meltem Soylev Bajin Oya Itil Ali Osman Saatci | 2011 | 国际眼科杂志2011，11，4： | 5 |
| 6 | V_2O_5-TiO_2催化剂光催化降解2,4-二氯苯酚:催化剂载体和表面活性剂的影响(英文)显示文摘采用固态分散法成功制备了表面活性剂修饰的不同V_2O_5含量的二元氧化物催化剂,运用X射线衍射、漫反射光谱、红外光谱、扫描电镜和N_2吸附-脱附法对该纳米复合物进行了表征,并在紫外光照射下考察了其光催化降解2,4-二氯苯酚的性能.结果表明,50 wt%,V_2O_5-TiO_2(记为50V_2O_5-TiO_2)表现出比单纯V_2O_5,TiO_2和P25更高的光催化活性,V_2O_5和TiO_2之间的相互作用会影响二元氧化物催化剂的光催化效率.CTAB和HTAB的修饰显著增加了50V_2O_5-TiO_2样品的催化效率,其中(50V_2O_5-TiO_2)-CTAB催化剂在反应30 min后表现出最高的2,4-二氯苯酚降解率(100%)和反应速率(2.22 mg/(L·min)).表面活性剂的加入能修饰二元氧化物中V_2O_5和TiO_2的光学和电子性质,从而显著提高其光催化活性. | Eda Sinirtas Meltem Isleyen Gulin Selda Pozan Soylu | 2016 | Chinese Journal of Catalysis2016，37，4： | 3 |
| 7 | Skin disorders in peritoneal dialysis patients:An underdiagnosed subject显示文摘AIM: To examine all skin changes in peritoneal dialysis(PD) patients followed up in our unit.METHODS: Patients on PD program for at least three months without any known chronic skin disease were included in the study. Patients with already diagnosed skin disease, those who have systemic diseases that may cause skin lesions, patients with malignancies and those who did not give informed consent were excluded from the study. All patients were examined by the same predetermined dermatologist with all findings recorded. The demographic, clinical and laboratory data including measures of dialysis adequacy of patients were recorded also. Statistical Package for Social Sciences(SPSS) for Windows 16.0 standard version was used for statistical analysis.RESULTS: Among the patients followed up in our PD unit, those without exclusion criteria who gave informed consent, 38 patients were included in the study with male/female ratio and mean age of 26/12 and 50.3 ± 13.7 years, respectively. The duration of CKD was 7.86 ± 4.16 years and the mean PD duration was 47.1 ± 29.6 mo. Primary kidney disease was diabetic nephropathy in 11, nephrosclerosis in six, uropathologies in four, chronic glomerulonephritis in three, chronic pyelonephritis in three, autosomal dominant polycystic kidney disease in three patients while cause was unknown in eight patients. All patients except for one patient had at least one skin lesion. Loss of lunula, onychomycosis and tinea pedis are the most frequent skin disorders recorded in the study group. Diabetic patients had tinea pedis more frequently(P = 0.045). No relationship of skin findings was detected with primary renal diseases, comorbidities and medications that the patients were using.CONCLUSION: Skin abnormalities are common in in PD patients. The most frequent skin pathologies are onychomycosis and tinea pedis which must not be overlooked. | Meltem Gursu Sami Uzun Derya Topcuoglu Leyli Kadriye Koc Lamiye Yucel Abdullah Sumnu Egemen Cebeci Oktay Ozkan Ahmet Behlul Leyla Koc Savas Ozturk Rumeyza Kazancioglu | 2016 | World Journal of Nephrology2016，5，4： | 3 |
| 8 | Ex-PRESS implantation for different types of glaucoma显示文摘AIM: To evaluate the clinical results, efficacy and safety of Ex-PRESS P200 glaucoma shunt implant in different types of medically uncontrolled glaucoma. METHODS: The study included 31 eyes of 31 patients that were unresponsive to medical antiglaucomatous therapy in whom Ex-PRESS P200 glaucoma shunt implantation was performed. The demographic characteristics of the patients, type of glaucoma, complete ocular examination results, number of antiglaucomatous drugs before and after surgery, early and late complications of surgery, additional surgical and nonsurgical medical interventions, and success rates were investigated from the patients’ files, retrospectively. RESULTS: The mean postoperative follow-up time was 16.4±7.5 mo. The preoperative mean corrected intraocular pressure(IOP) was 28.7±10.3 mm Hg and postoperative mean corrected IOP was 15.3±5.2 mm Hg(P<0.05) at the last visit. The mean IOP reduction was 39.9% when the preoperative and postoperative values of the last visits were compared. The average number of antiglaucomatous drug use decreased from 3.9±0.3 to 1.7±1.7 postoperatively(P<0.05). The use of antiglaucomatous medications at the last visit was more than in other studies in the literature. The most common complication was conjunctival leakage, which was seen in 7 patients. Other early complications were iris touch, intravitreal hemorrhage, hyphema, choroidal effusion, early transient hypotonia and corneal edema. One of the late complications was endophthalmitiswhich was seen in one case 6 mo after the operation, and the other late complication was opacification of the cornea in one patient. Twelve additional surgical operations associated to Ex-PRESS surgery and 3 bleb needling have done. At the last visit, the complete success rate was 32.3% and the qualified success rate was 77.5% in all patients. CONCLUSION: Ex-PRESS P200 glaucoma shunt implantation may be an effective procedure for medically uncontrolled glaucoma with significantly lower use of antiglaucomatous medications. | Meltem Guzin Altinel Ayse Yagmur Kanra Remzi Karadag Huseyin Bayramlar | 2019 | International Journal of Ophthalmology(English edition)2019，12，8： | 3 |
| 9 | Targeting molecular pathways for the treatment of inherited retinal degeneration显示文摘Inherited retinal degeneration is a major cause of incurable blindness characterized by loss of retinal photoreceptor cells.Inherited retinal degeneration is characterized by high genetic and phenotypic heterogeneity with several genes mutated in patients affected by these genetic diseases.The high genetic heterogeneity of these diseases hampers the development of effective therapeutic interventions for the cure of a large cohort of patients.Common cell demise mechanisms can be envisioned as targets to treat patients regardless the specific mutation.One of these targets is the increase of intracellular calcium ions,that has been detected in several murine models of inherited retinal degeneration.Recently,neurotrophic factors that favor the efflux of calcium ions to concentrations below toxic levels have been identified as promising molecules that should be evaluated as new treatments for retinal degeneration.Here,we discuss therapeutic options for inherited retinal degeneration and we will focus on neuroprotective approaches,such as the neuroprotective activity of the Pigment epithelium-derived factor.The characterization of specific targets for neuroprotection opens new perspectives together with many questions that require deep analyses to take advantage of this knowledge and develop new therapeutic approaches.We believe that minimizing cell demise by neuroprotection may represent a promising treatment strategy for retinal degeneration. | Meltem Kutluer Li Huang Valeria Marigo | 2020 | Neural Regeneration Research2020，15，10： | 2 |
| 10 | THE EVOLUTION OF FIELD DEPLOYABLE fNIR SPECTROSCOPY FROM BENCH TO CLINICAL SETTINGS显示文摘In the late 1980s and early 1990s,Dr.Britton Chance and his colleagues,using picosecond-long laser pulses,spearheaded the development of time-resolved spectroscopy techniques in an effort to obtain quantitative information about the optical characteristics of the tissue.These efforts by Chance and colleagues expedited the translation of near-infrared spectroscopy(NIRS)-based techniques into a neuroimaging modality for various cognitive studies.Beginning in the early 2000s,Dr.Britton Chance guided and steered the collaboration with the Optical Brain Imaging team at Drexel University toward the development and application of afield deployable continuous wave functional near-infrared spectroscopy(fNIR)system as a means to monitor cognitive functions,particularly during attention and working memory tasks as well as for complex tasks such as war games and air tra±c control scenarios performed by healthy volunteers under operational conditions.Further,these collaborative efforts led to various clinical applications,including traumatic brain injury,depth of anesthesia monitoring,pediatric pain assessment,and braincomputer interface in neurology.In this paper,we introduce how these collaborative studies have made fNIR an excellent candidate for specified clinical and research applications,including repeated cortical neuroimaging,bedside or home monitoring,the elicitation of a positive effect,and protocols requiring ecological validity.This paper represents a token of our gratitude to Dr.Britton Chance for his influence and leadership.Through this manuscript we show our appreciation by contributing to his commemoration and through our work we will strive to advance thefield of optical brain imaging and promote his legacy. | KURTULUS IZZETOGLU HASAN AYAZ ANNA MERZAGORA MELTEM IZZETOGLU PATRICIA ASHEWOKIS SCOTT CBUNCE KAMBIZ POURREZAEI ARYE ROSEN BANU ONARAL | 2011 | Journal of Innovative Optical Health Sciences2011，4，3： | 2 |
| 11 | 私募股权投资在美国页岩气基础设施建设中的新角色显示文摘页岩气已经成为美国能源结构中的重要组成部分。在不断发展的美国页岩气领域,高峰产量与气体收集和处理设施、管道的计划能力之间存在巨大差距,凸显了额外投资的必要性。页岩气资源的大规模开发已经吸引了许多建设中游设施的投资,但投资来源非常分散,基础设施建设缺乏统一的规划和协调。三类主要的基础设施建设投资来源是独立勘探开发公司、中游的业主有限合伙企业(MLP)和私募股权基金支持的中游公司。当前,由私募股权基金支持的业主有限合伙企业正成为基础设施投资的中坚。 | Chuck Chakravarthy Rachael Goydan Meltem Demirors 黄佳音 | 2010 | 国际石油经济2010，18，8： | 2 |
| 12 | Identification of Helicobacter species by 16S rDNA PCR and sequence analysis in human liver samples from patients with various etiologies of benign liver diseases显示文摘 | Mehmet Cindoruk Meltem Yalinay Cirak Selahattin Unal Tarkan Karakan Gulbanu Erkan Doruk Engin Sukru Dumlu Sevgi Turet | 2008 | European Journal of Gastroenterology & Hepatology2008，，1： | 2 |
| 13 | The effect of high-flux hemodialysis on renal anemia显示文摘 | Deniz A Meltem A Alper A | 2004 | Journal of Nephrology2004，17，5： | 1 |
| 14 | Coronary intervention for acute coronary syndrome in a 51 -year-old man with immune thrombocytope- nic purpura: a case report显示文摘 | Bora D Meltem A Fadime B | 2014 | J Med Case Rep2014，8，： | 1 |
| 15 | Determination of arsenic remowd efficiency by ferric ions using response surface methodology 显示文摘 | Meltem BB Aysecul P | 2009 | J Hazard Mater2009，166，： | 1 |
| 16 | Internet use among travel agencies in Turkey: An exp loratory study显示文摘 | Meltem Ozturan Sevgin Akis Roney | 2004 | Tourism Management2004，，4： | 1 |
| 17 | Improvement of bitumen and bituminous mixtures performances by triethylene glycol based synthetic polyboron显示文摘 | Deniz Arslan Metin Gürü M. Kür?at ?ubuk Meltem ?ubuk | 2011 | Construction and Building Materials2011，，10： | 1 |
| 18 | Influences of different stress media and high light intensities on accumu- lation of astaxanthin in the green alga Haematococcus pluvialis 显示文摘 | Esra I Meltem C D Fazilet V S | 2009 | New Biotech2009，26，34： | 1 |
| 19 | Preparation and characterization of starch-g- polymethacrylamide copolymers 显示文摘 | Meltem C | 2006 | J Polym Res2006，13，： | 1 |
| 20 | Inter - and intraobserver variability of 99Tc- DMSA renal scintigraphy: Impact of oblique views显示文摘 | Meltem C Pnar OK Erdem K | 2007 | J Nucl Med Techno12007，35，2： | 1 |
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