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| 1 | Assessment of the correlation between serum prolidase and alpha-fetoprotein levels in patients with hepatocellular carcinoma显示文摘AIM: To determine the predictive value of increased prolidase activity that reflects increased collagen turnover in patients with hepatocellular carcinoma(HCC).METHODS: Sixty-eight patients with HCC(mean age of 69.1 ± 10.1), 31 cirrhosis patients(mean age of59.3 ± 6.3) and 33 healthy volunteers(mean age of51.4 ± 12.6) were enrolled in this study. Univariate and multivariate analysis were used to evaluate the association of serum α-fetoprotein(AFP) values with HCC clinicopathological features, such as tumor size,number and presence of vascular and macrovascular invasion. The patients with HCC were divided into groups according to tumor size, number and presence of vascular invasion(diameters; ≤ 3 cm, 3-5 cmand ≥ 5 cm, number; 1, 2 and ≥ 3, macrovascular invasion; yes/no). Barcelona-clinic liver cancer(BCLC)criteria were used to stage HCC patients. Serum samples for measurement of prolidase and alphafetoprotein levels were kept at-80 ℃ until use.Prolidase levels were measured spectrophotometrically and AFP concentrations were determined by a chemiluminescence immunometric commercial diagnostic assay.RESULTS: In patients with HCC, prolidase and AFP values were evaluated according to tumor size, number,presence of macrovascular invasion and BCLC staging classification. Prolidase values were significantly higher in patients with HCC compared with controls(P <0.001). Prolidase levels were significantly associated with tumor size and number(P < 0.001, P = 0.002,respectively). Prolidase levels also differed in patients in terms of BCLC staging classification(P < 0.001).Furthermore the prolidase levels in HCC patients showed a significant difference compared with patients with cirrhosis(P < 0.001). In HCC patients grouped according to tumor size, number and BCLC staging classification, AFP values differed separately(P = 0.032,P = 0.038, P = 0.015, respectively). In patients with HCC, there was a significant correlation(r = 0.616; P< 0.001) between prolidase and AFP values in terms of tumor size, number and BCLC staging classification,whereas the presence of macrovascular invasion did not show a positive association with serum prolidase and AFP levels.CONCLUSION: Considering the levels of both serum prolidase and AFP could contribute to the early diagnosing of hepatocellular carcinoma. | Sevil Uygun Ilikhan Muammer Bilici Hatice Sahin Ayse Semra Demir Akca Murat Can Ibrahim Ilker Oz Berrak Guven M Cagatay Buyukuysal Yucel Ustundag | 2015 | World Journal of Gastroenterology2015，21，22： | 8 |
| 2 | Investigation of performance and emission characteristics of waste cooking oil as biodiesel in a diesel engine显示文摘Biodiesel is one of the most popular prospective alternative fuels and can be obtained from a variety of sources. Waste frying oil is one such source along with the various raw vegetable oils. However, some specific technical treatments are required to improve certain fuel properties such as viscosity and calorific value of the biodiesel being obtained from waste cooking oil methyl ester(WCOME). Various treatments are applied depending on the source and therefore the composition of the cooking oil. This research investigated the performance of WCOME as an alternative biofuel in a four-stroke direct injection diesel engine. An 8-mode test was undertaken with diesel fuel and five WCOME blends. The best compromise blend in terms of performance and emissions was identified. Results showed that energy utilization factors of the blends were similar within the range of the operational parameters(speed, load and WCOME content). Increasing biodiesel content produced slightly more smoke and NOx for a great majority of test points, while the CO and THC emissions were lower. | Yahya Ulusoy Rldvan Arslan Yucel Tekin Ali Surmen Alper Bolat Remzi Sahin | 2018 | Petroleum Science2018，15，2： | 2 |
| 3 | Gastric Necrosis due to Acute Massive Gastric Dilatation显示文摘 | Ibrahim Aydin Ahmet Pergel Ahmet Fikret Yucel Dursun Ali Sahin Ender Ozer Yasuhiko Sugawara | 2013 | <journal-title>Case Reports in Medicine2013，，： | 1 |
| 4 | Proanthocyanidin prevents myocardial ischemic injury in adult rats显示文摘 | GULER A SAHIN M A YUCEL O | 2011 | Med Sci Monit2011，17，11： | 1 |
| 5 | Erythrocyte membrane glycation and Na( + ) - K ( -) levels in NIDDM 显示文摘 | Umudum F Yucel 0 Sahin Y | 2002 | J Diabetes Complications2002，16，5： | 1 |
| 6 | Removal of propham from water by using electro-Fenton technology: Kinetics and mechanism显示文摘 | Alican Yucel Sahin Mehmet A | 2008 | Chemosphere2008，73，： | 1 |
| 7 | Chloride removal from zinc ash显示文摘 | Cinar Sahin F Derin B Yucel O | 2000 | Scandinavian Journal of Metallurgy2000，29，5： | 1 |
| 8 | Proanthocyanidin prevents myocardial ischemic injury in adult rats显示文摘 | GULER A SAHIN M A YUCEL O | 2011 | Medical Science Monitor:International Medical Journal of Experimental and Clinical Research2011，17，11： | 1 |
| 9 | Circulating biomark ers of oxidative stress in complicated pregnancies显示文摘 | Orhan H Onderoglu L Yucel A Sahin G | 2003 | Arch Gynecol Obstet2003，267，： | 1 |
| 10 | Circulating biomarkers of oxidative stress in complicated pregnancies显示文摘 | Orhan H Onderoglu L Yucel A Sahin G | 2003 | Arch Gynecol Obstet2003，267，： | 1 |
| 11 | Proanthocyanidin prevents myo- cardial ischemic injury in adult rats 显示文摘 | Guler A Sahin MA Yucel O | 2011 | Med Sci Monit2011，17，11： | 1 |
| 12 | Microstructure and densification of ZrB 2 –SiC composites prepared by spark plasma sintering显示文摘 | Ipek Akin Mikinori Hotta Filiz Cinar Sahin Onuralp Yucel Gultekin Goller Takashi Goto | 2009 | Journal of the European Ceramic Society2009，，11： | 1 |
| 13 | Combined duplication of the colon and vermiform appendix in an adult patient显示文摘Combined duplication of the colon and vermiform appendix is one of the rare congenital anomalities of the alimentary tract. Only a few cases have been reported in the adult population. A 28-year-old man presented to the clinic with a mass in the right flank. Imaging showed only a hydronephrotic atrophic kidney. The f inal diagnosis was only available at exploration. Combined duplication of the tubular colon and vermiform appendix was conf irmed histopathologically. The patient was treated with nephrectomy and complete resection of the duplicated colon and vermiform appendix. The patient recovered uneventfully,and has done well for the past year. This is believed to be one of the first reports of combined duplication of the tubular colon and vermiform appendix as a cause of hydronephrotic atrophic kidney in an adult patient. | Sahin Kabay Mehmet Yucel Faik Yaylak Alper Hacioglu Mustafa C Algin Esra G Olgun Levent Sahin Tayfun Aydin | 2008 | World Journal of Gastroenterology2008，14，4： | 1 |
| 14 | Chloride removal from zinc ash 显示文摘 | SAHIN F C DER1N B YUCEL O | 2000 | Scandinavian Journal of Metallurgy2000，29，5： | 1 |
| 15 | Determination of paraectamol based on electropolymerized-moleeularly imprinted polypyrrole modified pencil graphite electrode 显示文摘 | Levent Ozcan Yucel Sahin | 2007 | Seas Actuators B : Chem2007，127，2： | 1 |
| 16 | Proanthocyanidin preventsmyocardial ischemic injury in adult rats显示文摘 | GULER A SAHIN M YUCEL O | 2011 | Medical Science Monitor:International Medical Journal of Experimental and Clinical Research2011，17，11： | 1 |
| 17 | Determination of paracetarnol based electropolymerizecl -molecularly imprinted polypyrrole modified pencil graphite electrode 显示文摘 | Levent Ozcan Yucel Sahin | 2007 | Sensors and Actuators of Chemical B2007，127，2： | 1 |
| 18 | A reduction study of copper slag in a DC arc furnace显示文摘 | Yucel O Sahin F C Sirin B | 2005 | Scandinavian Journal of Metallurgy2005，28，3： | 1 |
| 19 | Ionchromatography Po- tentiometric Detection of Inorganic Anions and Cations Using Polypyrrole and Overoxidized Polypyrrole Electrode 显示文摘 | Mutlu Sahin Yucel Sahin Adnan Ozean | 2008 | Sensors and Actuators B2008，133，： | 1 |
| 20 | Proanthoeyanidin pre- vents myocardial ischemic injury in adult rats 显示文摘 | Guler A Sahin M A Yucel O | 2011 | Med Sei Monlt2011，17，11： | 1 |
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