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1Total thyroidectomy is safer with identification of recurrent laryngeal nerve显示文摘Objective:To investigate the effect of recurrent laryngeal nerve(RLN)identification on the complications after total thyroidectomy and lobectomy.Methods:Total 134 consecutive patients undergoing total thyroidectomy or thyroid lobectomy from January 2003 to November 2004 were investigated retrospectively.Patients were divided into two groups:RLN identified (Group A)or not(Group B).The two groups were compared for RLN injury and hypocalcaemia.Results:The numbers of patients and nerves at risk were 71 and 129 in Group A,and 63 and 121 in Group B,respectively.RLN injury in Group A(0)was sig- nificantly lower than that in Group B(57.9%)patients,75.8%nerves)for the numbers of patients(P=0.016)and nerves at risk (P=0.006).Temporary hypocalcaemia was significantly higher in Group A than in Group B(1424.1%vs 610.3%,P=0.049). Permanent complications in Group B were significantly higher than those in Group A(1320.6%vs 45.6%,P=0.009).Con- clusion:RLN injury was prevented and permanent complications were decreased by identifying the whole course and branches of the recurrent laryngeal nerve during total thyroidectomy.Hakan CANBAZ Musa DIRLIK Tahsin COLAK Koray OCAL Tamer AKCA Oner BILGIN Bahar TASDELEN Suha AYDIN 2008Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2008,9,6:20
2Use of albendazole sulfoxide, albendazole sulfone, and combined solutions as scolicidal agents on hydatid cysts (in vitro study)显示文摘AIM: To establish which scolicidal agents are superiorand more suitable for regular use.METHODS: Echinococcus granulosus protoscoleceswere obtained from 25 patients with liver hydatidcysts. Various concentrations of albendazole sulfone,albendazole sulfoxide, and albendazole sulfone andalbendazole sulfoxide mixed together in concentrationsof 50 μg/mL, and H2O2 in a concentration of 4%, NaCl20%, and 1.5% cetrimide-0.15% chlorhexidine (10%Savlon-Turkey) were used to determine the scolicidaleffects. Albendazole (ABZ) derivatives and otherscolicidal agents were applied to a minimum of 100scoleces for 5 and 10 min. The degree of viability wascalculated according to the number of living scolicesper fi eld from a total of 100 scolices observed underthe microscope.RESULTS: After 5 min, ABZ sulfone was 97.3%effective, ABZ sulfoxide was 98.4% effective, and thecombined solution was 98.6% effective. When sulfone,sulfoxide and the combined solutions were compared,the combined solution seemed more effective thansulfone. However, there was no difference when thecombined solution was compared with sulfoxide. After10 min, hypertonic salt water, sulfone, sulfoxide, andthe combined solution compared to other solutionslooked more effective and this was statisticallysignificant on an advanced level. When sulfone,sulfoxide, and the combined solutions were compared with each other, the combined solution appeared more effective than sulfone. When the combined solution was compared with sulfoxide, there was no difference.CONCLUSION: Despite being active, ABZ metabolites did not provide a marked advantage over 20% hypertonic saline. According to these results, we think creating a newly improved and more active preparation is necessary for hydatid cyst treatment.Gokhan Adas Soykan Arikan Ozgur Kemik Ali Oner Nilgun Sahip Oguzhan Karatepe 2009World Journal of Gastroenterology2009,15,1:19
3Effect of BMI on outcomes of surgical treatment for tibial plateau fractures: A comparative retrospective case series study显示文摘Yasar Mahsut Dincel All Oner Yavuz Arikan Sever Caglar Rasit Ozcafer Mehmet Akif Gulec 2018Chinese Journal of Traumatology2018,21,2:7
4Endoscopic tympanoplasty显示文摘Middle ear surgery is usually performed using a surgical microscope. Initially, in otorhinolaryngology practice, endoscopes were used for paranasal sinus surgeries. It was only later that they were applied in the area of otology. In otologic surgeries, endoscopes were first used to visualize the middle ear, before being used to assist with visualization of instruments during cholesteatoma surgeries, although they are still not used alone in various otologic surgeries. As in other surgical fields, there is also a trend towards minimally invasive intervention in the field of otorhinolaryngology. Smaller incisions performed under the guidance of endoscopes are preferred over conventional large incisions. Using this approach, improved outcomes can be achieved and postoperative morbidities can be reduced. In addition, the outcomes of grafts performed using the endoscopic approach are similar to that achieved by the microscopic approach. Therefore, endoscopic ear surgery implementations are becoming increasingly popular.Abdulvahap Akyigit Oner Sakallioglu Turgut Karlidag 2017Journal of Otology2017,12,2:6
5Immediate intraocular pressure rise after intravitreal injection of ranibizumab and two doses of triamcinolone acetonide显示文摘AIM: To evaluate prospectively immediate intraocular pressure (IOP) changes after the intravitreal injection of ranibizumab, 2 and 4mg triamcinolone acetonide. METHODS: Patients who underwent intravitreal injection of 0.1mL (4mg) triamcinolone acetonide (TA, Group T4), 0.05mL (2mg) TA (Group T2) and 0.05mL (0.5mg) ranibizumab (Group R) comprised the study population. Overall, 229 eyes of 205 patients were injected. Fifty-four eyes (23.6%) were in Group T4, 69 eyes (30.1%) in Group T2 and 106 eyes (46.3%) in Group R. If IOP was less than 26mmHg immediately after the injection no further measurement was performed. If IOP was ≥26mmHg, IOP was remeasured till the reading was below 26mmHg at 5, 15 and 30 minutes. RESULTS: Immediately after the injection, the IOP of 28 eyes (51.9%) in Group T4, 22 eyes (31.9%) in Group T2 and 51 eyes (48.1%) in Group R were over 25mmHg. At 30 minutes, IOP of one eye (1.9%) in group T4, two eyes (2.9%) in group T2 and two eyes (1.9 %) in Group R were over 25mmHg. Immediate post-injection IOP was significantly higher in Group T4 and Group R when compared to Group T2 (P <0.001 and P <0.001, respectively). IOP was significantly higher in eyes without vitreous reflux when compared to those with vitreous reflux in all groups (P <0.001). CONCLUSION: IOP may remarkably increase immediately after the intravitreal injection of 2 or 4mg triamcinolone acetonide, and 0.5mg ranibizumab. Absence of vitreous reflux is the most important predicting factor for immediate IOP rise after the injection.Gul Arikan Ali Osman Saatci Ferit Hakan Oner 2011International Journal of Ophthalmology(English edition)2011,4,4:6
6General characteristics of patients with electrolyte imbalance admitted to emergency department显示文摘BACKGROUND:Fluid and electrolyte balance is a key concept to understand for maintaining homeostasis,and for a successful treatment of many metabolic disorders.There are various regulating mechanisms for the equilibrium of electrolytes in organisms.Disorders of these mechanisms result in electrolyte imbalances that may be life-threatening clinical conditions.In this study we defined the electrolyte imbalance characteristics of patients admitted to our emergency department.METHODS:This study was conducted in the Emergency Department(ED) of Uludag University Faculty of Medicine,and included 996 patients over 18 years of age.All patients had electrolyte imbalance,with various etiologies other than traumatic origin.Demographic and clinical parameters were collected after obtaining informed consent from the patients.The ethical committee of the university approved this study.RESULTS:The mean age of the patients was 59.28±16.79,and 55%of the patients were male.The common symptoms of the patients were dyspnea(14.7%),fever(13.7%),and systemic deterioration(11.9%);but the most and least frequent electrolyte imbalances were hyponatremia and hypermagnesemia,respectively.Most frequent findings in physical examination were confusion(14%),edema(10%) and rales(9%);and most frequent pathological findings in ECG were tachycardia in24%,and atrial fibrillation in 7%of the patients.Most frequent comorbidity was malignancy(39%).Most frequent diagnoses in the patients were sepsis(11%),pneumonia(9%),and acute renal failure(7%).CONCLUSIONS:Electrolyte imbalances are of particular importance in the treatment of ED patients.Therefore,ED physicians must be acknowledged of their fluid-electrolyte balance dynamics and general characteristics.Arif Kadri Balci Ozlem Koksal Ataman Kose Erol Armagan Fatma Ozdemir Taylan Inal Nuran Oner 2013World Journal of Emergency Medicine2013,4,2:3
7Umbilical cord derived mesenchymal stem cell implantation in retinitis pigmentosa: a 6-month follow-up results of a phase 3 trial显示文摘AIM:To investigate the efficacy and the safety of umbilical cord derived mesenchymal stem cell(UC-MSC)implantation in patients with retinitis pigmentosa(RP).METHODS:This prospective,single-center,phase 3 clinical study enrolled 124 eyes of 82 RP patients.The patients received 5 million UC-MSCs to the suprachoroidal area with a surgical procedure.Patients were evaluated on the 1st day,1st,and 6th months postoperatively.Best corrected visual acuity(BCVA),anterior segment and fundus examinations,color photography,optical coherence tomography(OCT),and visual field(VF)tests were carried out at each visit.Fundus fluorescein angiography(FFA)and multifocal electroretinography(mfERG)recordings were performed at the end of the 6th month.Ocular and systemic adverse events of the surgical procedure were also noted.RESULTS:All of the 82 patients completed the 6-month follow-up period.None of them had any serious systemic or ocular complications.There were statistically significant improvements in BCVA and VF during the study(all P<0.05).The amplitudes of the P1 waves in the central areas showed significant improvements in mfERG recordings.There were also significant increases in implicit times of P1 waves in the central areas.CONCLUSION:Suprachoroidal administration of UC-MSCs has beneficial effect on BCVA,VF,and mfERG measurements during the 6-month follow-up period.Cell mediated therapy based on the secretion of growth factors(GFs)seems to be an effective and safe option for degenerative retinal diseases.Neslihan Sinim Kahraman Ayse Oner 2020International Journal of Ophthalmology(English edition)2020,13,9:2
8Imaging findings in Mondor's disease显示文摘Yanik B Conkbayir I Oner O 2003J Clin Ultrasound2003,31,2:1
9The reduction of endplate fractures during balloon vertebroplasty:a detailed radiological analysis of the treatment of burst fractures using pedicle screws,balloon vertebroplasty,and calcium phosphate cement显示文摘Verlaan JJ van de Kraats EB Oner FC 2005Spine2005,30,16:1
10Effects of streptozotocin - induced diabetes and pentylenetetrazol - induced seizure on brain cortex ( Ca^2+ ) ATPase activity in rats显示文摘Oner P Kocak H Oztas B 2000Int J Neurosci2000,103,14:1
11Tumour angiogenesis and mast cell density in the prognostic assessment of colorectal carcinomas显示文摘Acikalin MF Oner U Topcu I 2005Dig Liver Dis2005,37,3:1
12Electroretinographic findings in Duchenne/Becker muscular dystrophy and correlation with genotype显示文摘Ulgenalp A Oner FH Soylev MF 2002Ophthalmic Genet2002,23,3:1
13Effect of vita- min E treatment on the oxidative damage occurring in Henoeh- Seh5nlein purpura 显示文摘Erdo:an O Oner A Aydin A 2003Aeta Paediatr2003,92,5:1
14Anterior spinal column augmentation with injectable bone cements显示文摘Verlann JJ Oner FC Dhert WJ 0,,3:1
15Ceftriaxone-associated biliary pseudolithiasis in children显示文摘Biner B Oner N Celtik C 0,,5:1
16Spinal Tuberculosis显示文摘Safak Ekinci Oner Tatar Serkan Akpancar 2015Journal of Experimental Neuroscience2015,,9:1
17The effect of the treatment of high dose roethylprednisolone on Na+-K+Mg2+ ATPase activity and lipid peroxidation and ultrustructural findings following cerebral contusion in rat显示文摘Ildan F Polat S Oner A 1995Surg Neurol1995,44,6:1
18Efficacy of intra-articular sodium hyaluronate in the treatment of knee osteoarthritis显示文摘Tasciotaoglu F Oner C 2003Clin Rheumatol2003,22,:1
19Multiple mechanisms of ketamine blockade of N-methyl-D-aspaitate receptore显示文摘Oner BA Pennefather PS MacDonald JF 1997Anesthesiology1997,86,4:1
20Simulation of a closed cement grinding circuit 显示文摘Lynch A J Oner M Benzer H 2000Zement - Kalk - Gips2000,10,53:1
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