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| 1 | What operation for recurrent rectal prolapse after previous Delorme's procedure? A practical reality显示文摘AIM: To report our experience with perineal repair(Delorme's procedure) of rectal prolapse with particular focus on treatment of the recurrence.METHODS: Clinical records of 40 patients who underwent Delorme's procedure between 2003 and 2014 were reviewed to obtain the following data: Gender; duration of symptoms, length of prolapse, operation time, ASA grade, length of post-operative stay, procedure-related complications, development and treatment of recurrent prolapse. Analysis of post-operative complications, rate and time of recurrence and factors influencing the choice of the procedure for recurrent disease was conducted. Continuous variables were expressed as the median with interquartile range(IQR). Statistical analysis was carried out using the Fisher exact test.RESULTS: Median age at the time of surgery was 76 years(IQR: 71-81.5) and there were 38 females and 2 males. The median duration of symptoms was 6 mo(IQR: 3.5-12) and majority of patients presented electively whereas four patients presented in the emergency department with irreducible rectal prolapse. The median length of prolapse was 5 cm(IQR: 5-7), median operative time was 100 min(IQR: 85-120) and median post-operative stay was 4 d(IQR: 3-6). Approximately16% of the patients suffered minor complications such as- urinary retention, delayed defaecation and infected haematoma. One patient died constituting postoperative mortality of 2.5%. Median follow-up was 6.5 mo(IQR: 2.15-16). Overall recurrence rate was 28%(n = 12). Recurrence rate for patients undergoing an urgent Delorme's procedure who presented as an emergency was higher(75.0%) compared to those treated electively(20.5%), P value 0.034. Median time interval from surgery to the development of recurrence was 16 mo(IQR: 5-30). There were three patients who developed an early recurrence, within two weeks of the initial procedure. The management of the recurrent prolapse was as follows: No further intervention(n = 1), repeat Delorme's procedure(n = 3), Altemeier's procedure(n = 5) and rectopexy with faecal diversion(n = 3). One patient was lost during follow up.CONCLUSION: Delorme's procedure is a suitable treatment for rectal prolapse due to low morbidity and mortality and acceptable rate of recurrence. The management of the recurrent rectal prolapse is often restricted to the pelvic approach by the same patientrelated factors that influenced the choice of the initial operation, i.e., Delorme's procedure. Early recurrence developing within days or weeks often represents a technical failure and may require abdominal rectopexy with faecal diversion. | Muhammad A Javed Faryal G Afridi Dmitri Y Artioukh | 2016 | World Journal of Gastrointestinal Surgery2016，8，7： | 4 |
| 2 | Robotic total meso-rectal excision for rectal cancer: A systematic review following the publication of the ROLARR trial显示文摘AIM To compare outcomes in patients undergoing rectal resection by robotic total meso-rectal excision(RTME) vs laparoscopic total meso-rectal excision(LTME).METHODS Standard medical electronic databases such as Pub-Med, MEDLINE, EMBASE and Scopus were searched to find relevant articles. The data retrieved from all types of included published comparative trials in pati-ents undergoing RTME vs LTME was analysed using the principles of meta-analysis. The operative, post-operative and oncological outcomes were evaluated to assess the effectiveness of both techniques of TME. The summated outcome of continuous variables was expressed as standardized mean difference(SMD) and dichotomous data was presented in odds ratio(OR).RESULTS One RCT(ROLARR trial) and 27 other comparative studies reporting the non-oncological and oncological outcomes following RTME vs LTME were included in this review. In the random effects model analysis using the statistical software Review Manager 5.3, the RTME was associated with longer operation time(SMD, 0.46; 95%CI: 0.25, 0.67; z = 4.33; P = 0.0001), early passage of first flatus(P = 0.002), lower risk of conversion(P = 0.00001) and shorter hospitalization(P = 0.01). The statistical equivalence was seen between RTME and LTME for non-oncological variables like blo-od loss, morbidity, mortality and re-operation risk. The oncological variables such as recurrence(P = 0.96), number of harvested nodes(P = 0.49) and positive circumferential resection margin risk(P = 0.53) were also comparable in both groups. The length of distal resection margins was similar in both groups. CONCLUSION RTME is feasible and oncologically safe but failed to demonstrate any superiority over LTME for many sur-gical outcomes except early passage of flatus, lower risk of conversion and shorter hospitalization. | Katie Jones Mohamed G Qassem Parv Sains Mirza K Baig Muhammad S Sajid | 2018 | World Journal of Gastrointestinal Oncology2018，10，11： | 4 |
| 3 | Microfacies and Depositional Environments of Miocene Isolated Carbonate Platforms from Central Luconia, Offshore Sarawak, Malaysia显示文摘The Luconia Province-offshore Sarawak-is a key geological unit for understanding the distribution of hydrocarbon resources in Malaysia. Nevertheless, little effort has been made to address the palaeoenvironmental characteristics of the Tertiary carbonates in the key sector of Central Luconia.We study the sedimentology and petrography of core samples from a well in Central Luconia, for which thirteen microfacies have been identified reflecting different depositional settings. This is the first microfacies scheme elaborated for Luconian carbonates. Lithofacies and microfacies distribution are compatible with deposition in a reef complex, originating around a framework reef, within the euphotic zone. Sediments were deposited in environments of backreef, reef crest, and forereef. The fair weather wave base is marked by the presence of coralline red algae, foraminifera, decreasing degree of bioclast fragmentation and other microfacies features. As a result, a depositional-environmental model is constructed, depicting a reef complex built around a framework reef developed on the margin of an isolated platform. In addition, an innovative, preliminary time series analysis of facies, microfacies and depositional environment data reveal the existence of seasonal cycles in the stacking patterns of facies and microfacies. | Hammad Tariq JANJUHAH José Antonio GáMEZ VINTANED Ahmed Mohamed Ahmed SALIM Ibrahima FAYE Mumtaz Muhammad SHAH Deva Prasad GHOSH | 2017 | Acta Geologica Sinica(English Edition)2017，91，5： | 2 |
| 4 | Flt3L and TK gene therapy eradicate multifocal glioma in a syngeneic glioblastoma model 显示文摘 | KING G D MUHAMMAD A K CURTIN J F | 2008 | Neuro Oncol2008，10，1： | 1 |
| 5 | Novel chiral pyrrolidinone scaffolds derived from threonine with antibacterial activity显示文摘 | Muhammad A Cowley Andrew R Moloney Mark G | 2010 | Tetrahedron: Asymmetry2010，21，1314： | 1 |
| 6 | Information Regarding Agronomic Practices and Plant Protection Measures Obtained by the Farmers through Electronic Media显示文摘 | Khan G A Muhammad S Ch K M | 2013 | Journal of Animal and Plant Sciences2013，23，2： | 1 |
| 7 | Strict group testing and the set basis problem显示文摘 | Damaschke P Muhammad A S Wiener G | 2014 | Journal of Combinator[M Theory Series A2014，126，： | 1 |
| 8 | Polarised finite difference analysis of D-fiber and applications for chemical sensing显示文摘 | MUHAMMAD F A STEWART G | 1992 | Int J Optoelectron1992，7，6： | 1 |
| 9 | Effect of nickel loading on hydrogenproduction and chemical oxygen demand(COD)destruction from glucose oxidation and gasification insupercritical water显示文摘 | Youssef Emhemmed A Chowdhury Muhammad B I Nakhla G | 2010 | International Journal of HydrogenEnergy2010，35，10： | 1 |
| 10 | Immunomodulatory effect of various anti-parasitics:a review显示文摘 | SAJID M S IQBAL Z MUHAMMAD G | 2006 | Parasitology2006，132，3： | 1 |
| 11 | Comparative prevalence of streak canal and intramammary microorganisms and their contemporaneous association in a dairy cow and buffalo herd lacking mastitis control program显示文摘 | Javed S Muhammad G Saqib M | 2015 | Int J Agric Biol2015，17，： | 1 |
| 12 | BAI 3, CDX 2 and VIL 1: a panel of three antibodies to distinguish small cell from large cell neuroendocrine lung carcinomas显示文摘 | Muhammad F Bari Helen Brown Andrew G Nicholson Keith M Kerr John R Gosney William A Wallace Irshad Soomro Salli Muller Danielle Peat Jonathan D Moore Lesley A Ward Maxim B Freidin Eric Lim Manu Vatish David R J Snead | 2014 | Histopathology2014，，： | 1 |
| 13 | Porous TiNi alloy by metal injection moulding sintering of ele- mental powders: effect of sintering temperature显示文摘 | Muhammad H I Russe 11 G Hywel A | 2012 | materials letters2012，，70： | 1 |
| 14 | Stem cells in normal breast development and breast cancer显示文摘 | Dontu G Muhammad A H Abdallah W M | 2003 | Cell Proliferation2003，36，1： | 1 |
| 15 | Neuronal estrogen receptor-alpha mediates neuroprotection by 17beta-es- tradiol显示文摘 | Elzer J G Muhammad S Wintermantel T M | 2010 | J Cereb Blood Flow Metab2010，30，5： | 1 |
| 16 | Passive copy move image forgery detection using undecimated dyadic wavelet transform 显示文摘 | Muhammad G Hussain M Bebis G | 2012 | Digital Investigation2012，9，1： | 1 |
| 17 | Organotin esters of 3-( 2-furanyl ) -2-propenoic acid : their characterization and biological activity 显示文摘 | DANISH MUHAMMAD AI T ttE BADSHAH AM IN | 1995 | J Organomet Chem1995，486，12： | 1 |
| 18 | Effects of dietary formalin on the health and testicular pathology of male Japanese quails (Coturnixcoturnix japonica ) 显示文摘 | Anwar M I Khan M Z Muhammad G | 2001 | Veterinary & Human Toxicology2001，43，： | 1 |
| 19 | Effect of Ivermectin on the cellular and humoral immune responses of rabbits 显示文摘 | Sajid M S Iqbal Z Muhammad G | 2007 | Life Sciences2007，80，21： | 1 |
| 20 | Logarithm of short-time fourier transform for extending the seismic bandwidth 显示文摘 | MUHAMMAD S DEVA G | 2014 | Geophysical Prospecting2014，62，： | 1 |
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