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| 1 | 全球食品和饲料链中生物毒素早期预警、监测和毒性评估的挑战和解决方案显示文摘确保世界人口不断增长下的食品供应安全和保障是巨大和紧迫的需求。然而,全球农业和食品行业仍易受植物、藻类,尤其是真菌产生的生物毒素污染问题的挑战;随着全球变暖和极端天气事件频发,这些有毒代谢产物的发生愈发难以预测。为了提升食品和饲料链中生物毒素的预警、监测和毒性评估方法,总结在各个科学领域和方法中创新所需的多学科、多部门互补能力,具体包括使用卫星和无人机成像的大数据方法、便携式监测设备以及使用蛋白质组学和转录组学对(新兴)生物毒素进行(联合)毒性测试。 | Rudolf Krska Eskola Mari Berthiller Franz Nielen Michel Oswald Isabelle Elliott Chris McNerney Oonagh BotanaLuis Miguel MalachováAlexandra | 2021 | 粮油食品科技2021，29，6： | 2 |
| 2 | Detection of Myocardial Damage in Patients With Sarcoidosis显示文摘 | Manesh R. Patel Peter J. Cawley John F. Heitner Igor Klem Michele A. Parker Wael A. Jaroudi Trip J. Meine James B. White Michael D. Elliott Han W. Kim Robert M. Judd Raymond J. Kim | 2009 | Circulation2009，，： | 2 |
| 3 | Performance of Delayed-Enhancement Magnetic Resonance Imaging With Gadoversetamide Contrast for the Detection and Assessment of Myocardial Infarction: An International, Multicenter, Double-Blinded, Randomized Trial显示文摘 | Raymond J. Kim Timothy S.E. Albert James H. Wible Michael D. Elliott John C. Allen Jennifer C. Lee Michele Parker Alicia Napoli Robert M. Judd | 2008 | Circulation2008，，5： | 1 |
| 4 | Using digital image analysis and spectral reflectance data to quantify damage by greenbug (Hemitera: Aphididae) in winter wheat 显示文摘 | Mirik M Michels G J Elliott N C | 2006 | Computers and Electronics in Agriculture2006，51，12： | 1 |
| 5 | Reflectance characteristics of Russian wheat aphid (Hemiptera: Aphididae) stress and abundance in winter wheat显示文摘 | Mirik M Michels G J Elliott N C | 2007 | Electronics in Agriculture2007，57，2： | 1 |
| 6 | Assembly and specific recognition of k29- and k33-1inked polyubiquitin显示文摘 | Michel MA Elliott PR Swatek KN | 2015 | Mol Cell2015，58，1： | 1 |
| 7 | Pharmacodynamic effect and clinical efficacy of clopidogrel and prasugrel with or without a proton-pump inhibitor: an analysis of two randomised trials显示文摘 | Michelle L O’Donoghue Eugene Braunwald Elliott M Antman Sabina A Murphy Eric R Bates Yoseph Rozenman Alan D Michelson Raymond W Hautvast Peter N Ver Lee Sandra L Close Lei Shen Jessica L Mega Marc S Sabatine Stephen D Wiviott | 2009 | The Lancet2009，，9694： | 1 |
| 8 | Contrast-enhanced MRI and routine single photon emission computed tomography (SPECT) perfusion imaging for detection of subendocardial myocardial infarcts: an imaging study显示文摘 | Anja Wagner Heiko Mahrholdt Thomas A Holly Michael D Elliott Matthias Regenfus Michele Parker Francis J Klocke Robert O Bonow Raymond J Kim Robert M Judd | 2003 | The Lancet2003，，9355： | 1 |
| 9 | Are Patients with Esophageal Cancer Who Become PET Negative after Neoadjuvant Chemoradiation Free of Cancer?显示文摘 | James M. McLoughlin Marcovalerio Melis Erin M. Siegel E. Michelle Dean Jill M. Weber Jeannie Chern Melanie Elliott Scott T. Kelley Richard C. Karl | 2008 | Journal of the American College of Surgeons2008，，5： | 1 |
| 10 | 2013 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy显示文摘 | Michele Brignole Angelo Auricchio Gonzalo Baron-Esquivias Pierre Bordachar Giuseppe Boriani Ole-A Breithardt John Cleland Jean-Claude Deharo Victoria Delgado Perry M. Elliott Bulent Gorenek Carsten W. Israel Christophe Leclercq Cecilia Linde Lluís Mont Lu | 2013 | European Heart Journal2013，，29： | 1 |
| 11 | 2013 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy显示文摘 | Michele Brignole Angelo Auricchio Gonzalo Baron-Esquivias Pierre Bordachar Giuseppe Boriani Ole-A Breithardt John Cleland Jean-Claude Deharo Victoria Delgado Perry M. Elliott Bulent Gorenek Carsten W. Israel Christophe Leclercq Cecilia Linde Lluís Mont Lu | 2013 | European Heart Journal2013，，29： | 1 |
| 12 | Pharmacodynamic effect and clinical efficacy of clopidogrel and prasugrel with or without a proton-pump inhibitor:an analysis of two randomised trials显示文摘 | Michelle L Eugene B Elliott MA | 2009 | Lancet2009，374，9694： | 1 |
| 13 | The molecular genetics of chronic neutrophilic leukaemia: defining a new era in diagnosis and therapy显示文摘 | Michelle A. Elliott Ayalew Tefferi | 2014 | Current Opinion in Hematology2014，，2： | 1 |
| 14 | Global Challenges and Solutions in the Early Warning,Monitoring and Toxicity Assessment of Biotoxins in the Food and Feed Chain显示文摘There is a massive and urgent need to ensure safety and security of the food supply of the world´s growing population.However,global agriculture and food industries continue to be vulnerable to problems of contamination with biotoxins produced by plants,algae and particularly by fungi;with global warming and extreme weather events making the occurrence of these toxic metabolites even more unpredictable.In this paper we summarize the multidisciplinary,multi-sectoral complementary competencies needed to innovate in various scientific fields and approaches,so strongly needed to develop improved early warning,monitoring and toxicity assessment of biotoxins in the food and feed chain.These include big data approaches using satellite and drone images,portable monitoring devices and(combined)toxicity testing of(emerging)biotoxins using proteomics and transcriptomics. | Rudolf Krska Eskola Mari Berthiller Franz Nielen Michel Oswald Isabelle Elliott Chris McNerney Oonagh BotanaLuis Miguel MalachováAlexandra | 2021 | 粮油食品科技2021，29，6： | 0 |
| 15 | Identification of fungal fossils and novel azaphilone pigments in ancient carbonised specimens of Hypoxylon fragiforme from forest soils of Chatillon-sur-Seine(Burgundy)显示文摘Fungal stromata were recently discovered in association with charcoal and burnt soil aggregates during an archaeological survey in the Chaˆtillon-sur-Seine forest massif.The wood and soil in the samples were dated to the medieval period(between 738 and 1411 AD).Light microscopy and scanning electron microscopy revealed that a few of the stromatal fragments still contained ascospores.Their macromorphological characters were described and secondary metabolite profiles were generated using high performance liquid chromatography with diode array and mass spectrometric detection(HPLC–DAD/MS).The combination of these two data lines then allowed species identification.Most of the fragments were assigned to Hypoxylon fragiforme,the type species of the Hypoxylaceae(Xylariales).Two further species whose stromata grew on the fossil charcoal could be tentatively identified as Jackrogersella cohaerens and(more tentatively)as Hypoxylon vogesiacum.These three species are still commonly encountered in the forests of Central Europe today.Furthermore,the HPLC-HRMS data of H.fragiforme suggested the presence of unknown azaphilone dimers and of further new pigments.These archaeological compounds were compared to fresh stromata of H.fragiforme collected in Germany and subjected to the same analytical protocol.While the major components in both samples were identified as the known mitorubrin type azaphilones and orsellinic acid,the chemical structures of seven novel complex azaphilone pigments,for which we propose the trivial names rutilins C-D and fragirubrins A-E,were elucidated using spectral methods(NMR and CD spectroscopy,high resolution mass spectrometry).It appears that these pigments had indeed persisted for millennia in the fossil stromata. | Frank Surup Abolfazl Narmani Lucile Wendt Sebastian Pfutze Robin Kretz Kevin Becker Cle ment Menbrives Alain Giosa Michelle Elliott Christophe Petit Manfred Rohde Marc Stadler | 2018 | Fungal Diversity2018，，5： | 0 |
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