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1Switchgrass Biochar Effects on Plant Biomass and Microbial Dynamics in Two Soils from Different Regions显示文摘Biochar amendments to soils may alter soil function and fertility in various ways, including through induced changes in the microbial community. We assessed microbial activity and community composition of two distinct clayey soil types, an Aridisol from Colorado(CO) in the U.S. Central Great Plains, and an Alfisol from Virginia(VA) in the southeastern USA following the application of switchgrass(Panicum virgatum) biochar. The switchgrass biochar was applied at four levels, 0%, 2.5%, 5%, and 10%, approximately equivalent to biochar additions of 0, 25, 50, and 100 t ha-1, respectively, to the soils grown with wheat(Triticum aestivum) in an eight-week growth chamber experiment. We measured wheat shoot biomass and nitrogen(N) content and soil nutrient availability and N mineralization rates, and characterized the microbial fatty acid methyl ester(FAME) profiles of the soils. Net N mineralization rates decreased in both soils in proportion to an increase in biochar levels, but the effect was more marked in the VA soil, where net N mineralization decreased from-2.1 to-38.4 mg kg-1. The 10% biochar addition increased soil p H, electrical conductivity, Mehlichand bicarbonate-extractable phosphorus(P), and extractable potassium(K) in both soil types. The wheat shoot biomass decreased from 17.7 to 9.1 g with incremental additions of biochar in the CO soil, but no difference was noted in plants grown in the VA soil. The FAME recovery assay indicated that the switchgrass biochar addition could introduce artifacts in analysis, so the results needed to be interpreted with caution. Non-corrected total FAME concentrations indicated a decline by 45% and 34% with 10% biochar addition in the CO and VA soils, respectively, though these differences became nonsignificant when the extraction efficiency correction factor was applied. A significant decline in the fungi:bacteria ratio was still evident upon correction in the CO soil with biochar. Switchgrass biochar had the potential to cause short-term negative impacts on plant biomass and alter soil microbial community structure unless measures were taken to add supplemental N and labile carbon(C).Charlene N.KELLY Francisco C.CALDERóN Verónica ACOSTA-MARTíNEZ Maysoon M.MIKHA Joseph BENJAMIN David W.RUTHERFORD Colleen E.ROSTAD 2015Pedosphere2015,25,3:11
2Effects of maternal diabetes on trophoblast cells显示文摘Diabetes mellitus(DM)is a health condition characterized by hyperglycemia over a prolonged period.There are three main types of DM:DM type 1(DM1),DM2 and gestational DM(GDM).Maternal diabetes,which includes the occurrence of DM1 and DM2 during pregnancy or GDM,increases the occurrence of gesttional complications and adverse fetal outcomes.The hyperglycemic intrauterine environment affects not only the fetus but also the placental development and function in humans and experimental rodents.The underlying mechanisms are still unclear,but some evidence indicates alterations in trophoblast proliferation,apoptosis and cell cycle control in diabetes.A proper coordination of trophoblast proliferation,differentiation and invasion is required for placental development.Initially,increased expression of proliferative markers in junctional and labyrinth zones of rat placentas and villous cytotrophoblast,syncytiotrophoblast,stromal cells and fetal endothelial cells in human placentas is reported among diabetics.Moreover,reduced apoptotic index and expression of some apoptotic genes are described in placentas of GDM women.In addition,cell cycle regulators including cyclins and cyclin-dependent kinase inhibitors seem to be affected by the hyperglycemic environment.More studies are necessary to check the balance between proliferation,apoptosis and differentiation in trophoblast cells during maternal diabetes.Marlúcia Bastos Aires Anne Carolline Veríssimo dos Santos 2015World Journal of Diabetes2015,6,2:9
3Small incision lenticule extraction(SMILE)in the correction of myopic astigmatism:outcomes and limitations-an update显示文摘Small Incision Lenticule Extraction(SMILE)is a flap-free intrastromal technique for the correction of myopia and myopic astigmatism.To date,this technique lacks automated centration and cyclotorsion control,so several concerns have been raised regarding its capability to correct moderate or high levels of astigmatism.The objective of this paper is to review the reported SMILE outcomes for the correction of myopic astigmatism associated with a cylinder over 0.75 D,and its comparison with the outcomes reported with the excimer laser-based corneal refractive surgery techniques.A total of five studies clearly reporting SMILE astigmatic outcomes were identified.SMILE shows acceptable outcomes for the correction of myopic astigmatism,although a general agreement exists about the superiority of the excimer laser-based techniques for low to moderate levels of astigmatism.Manual correction of the static cyclotorsion should be adopted for any SMILE astigmatic correction over 0.75 D.Jorge L.Aliódel Barrio Verónica Vargas Olena Al-Shymali Jorge L.Alió 2017Eye and Vision2017,4,1:8
4Laparoscopic approach in gastrointestinal emergencies显示文摘This review focuses on the laparoscopic approach to gastrointestinal emergencies and its more recent indications. Laparoscopic surgery has a specific place in elective procedures, but that does not apply in emergency situations. In specific emergencies, there is a huge range of indications and different techniques to apply, and not all of them are equally settle. We consider that the most controversial points in minimally invasive procedures are indications in emergency situations due to technical difficulties. Some pathologies, such as oesophageal emergencies, obstruction due to colon cancer, abdominal hernias or incarcerated postsurgical hernias, are nearly always resolved by conventional surgery, that is, an open approach due to limited intraabdominal cavity space or due to the vulnerability of the bowel. These technical problems have been solved in many diseases, such as for perforated peptic ulcer or acute appendectomy for which a laparoscopic approach has become a wellknown and globally supported procedure. On the other hand, endoscopic procedures have acquired further indications, relegating surgical solutions to a second place; this happens in cholangitis or pancreatic abscess drainage. This endoluminal approach avoids the need for laparoscopic development in these diseases. Nevertheless, new instruments and new technologies could extend the laparoscopic approach to a broader array of potentials procedures. There remains, however, a long way to go.Rosa M Jimenez Rodriguez Juan José Segura-Sampedro Mercedes Flores-Cortés Francisco López-Bernal Cristobalina Martín Verónica Pino Diaz Felipe Pareja Ciuro Javier Padillo Ruiz 2016World Journal of Gastroenterology2016,22,9:5
5Adjuvant therapy sparing in rectal cancer achieving complete response after chemoradiation显示文摘AIM:To evaluate the long-term results of conventional chemoradiotherapy and laparoscopic mesorectal excision in rectal adenocarcinoma patients without adjuvant therapy.METHODS:Patients with biopsy-proven adenocarcinoma of the rectum staged cT3-T4 by endoscopic ultrasound or magnetic resonance imaging received neoadjuvant continuous infusion of 5-fluorouracil for five weeks and concomitant radiotherapy.Laparoscopic surgery was planned after 5-8 wk.Patients diagnosed with ypT0N0 stage cancer were not treated with adjuvant therapy according to the protocol.Patients with ypT1-2N0 or ypT3-4 or N+were offered 5-fluorouracil-based adjuvant treatment on an individual basis.An external cohort was used as a reference for the findings.RESULTS:One hundred and seventy six patients were treated with induction chemoradiotherapy and 170underwent total mesorectal excision.Cancer staging of ypT0N0 was achieved in 26/170(15.3%)patients.After a median follow-up of 58.3 mo,patients withypT0N0 had five-year disease-free and overall survival rates of 96%(95%CI:77-99)and 100%,respectively.We provide evidence about the natural history of patients with localized rectal cancer achieving a complete response after preoperative chemoradiation.The inherent good prognosis of these patients will have implications for clinical trial design and care of patients.CONCLUSION:Withholding adjuvant chemotherapy after complete response following standard neoadjuvant chemoradiotherapy and laparoscopic mesorectal excision might be safe within an experienced multidisciplinary team.Xabier García-Albéniz Rosa Gallego Ralf Dieter Hofheinz Gloria Fernández-Esparrach Juan Ramón Ayuso-Colella Josep Antoni Bombí Carles Conill Miriam Cuatrecasas Salvadora Delgado Angels Ginés Rosa Miquel Mario Pagés Estela Pineda Verónica Pereira Aarón Sosa Oscar Reig Iván Victoria Luis Feliz Antonio María de Lacy Antoni Castells Iris Burkholder Andreas Hochhaus Joan Maurel 2014World Journal of Gastroenterology2014,20,42:5
6Management of oligometastatic non-small cell lung cancer patients:Current controversies and future directions显示文摘Oligometastatic non-small cell lung cancer(NSCLC)describes an intermediate stage of NSCLC between localized and widely-disseminated disease.This stage of NSCLC is characterized by a limited number of metastases and a more indolent tumor biology.Currently,the management of oligometastatic NSCLC involves radical treatment(radiotherapy or surgery)that targets the metastatic lesions and the primary tumor to achieve disease control.This approach offers the potential to achieve prolonged survival in patients who,in the past,would have only received palliative measures.The optimal therapeutic strategies for the different scenarios of oligometastatic disease(intracranial vs extracranial disease,synchronous vs metachronous)remain undefined.Given the lack of head-to-head studies comparing radiotherapy to surgery in these patients,the decision to apply surgery or radiotherapy(with or without systemic treatment)must be based on prognostic factors that allow us to classify patients.This classification will allow us to select the most appropriate therapeutic strategy on an individualized basis.In the future,the molecular or microRNA profiles will likely improve the treatment selection process.The objective of the present article is to review the most relevant scientific evidence on the management of patients with oligometastatic NSCLC,focusing on the role of radiotherapy and surgery.We also discuss areas of controversy and future directions.Felipe Counago Javier Luna Luis Leonardo Guerrero Blanca Vaquero María Cecilia Guillén-Sacoto Teresa González-Merino Begona Taboada Verónica Díaz Belén Rubio-Viqueira Ana Aurora Díaz-Gavela Francisco JoséMarcos Elia del Cerro 2019World Journal of Clinical Oncology2019,10,10:5
7Tools for the diagnosis of hepatitis C virus infection and hepatic fibrosis staging显示文摘Hepatitis C virus(HCV)infection represents a major public health issue.Hepatitis C can be cured bytherapy,but many infected individuals are unaware of their status.Effective HCV screening,fast diagnosis and characterization,and hepatic fibrosis staging are highly relevant for controlling transmission,treating infected patients and,consequently,avoiding end-stage liver disease.Exposure to HCV can be determined with high sensitivity and specificity with currently available third generation serology assays.Additionally,the use of point-of-care tests can increase HCV screening opportunities.However,active HCV infection must be confirmed by direct diagnosis methods.Additionally,HCV genotyping is required prior to starting any treatment.Increasingly,high-volume clinical laboratories use different types of automated platforms,which have simplified sample processing,reduced hands-on-time,minimized contamination risks and human error and ensured full traceability of results.Significant advances have also been made in the field of fibrosis stage assessment with the development of non-invasive methods,such as imaging techniques and serum-based tests.However,no single test is currently available that is able to completely replace liver biopsy.This review focuses on approved commercial tools used to diagnose HCV infection and the recommended hepatic fibrosis staging tests.Verónica Saludes Victoria González Ramon Planas Lurdes Matas Vicente Ausina Elisa Martró 2014World Journal of Gastroenterology2014,20,13:4
8共振态Z_(cs)(3985)、Z_(cs)(4003):分属SU(3)_f破缺的2个新型四夸克九重态?显示文摘BESⅢ和LHCb实验上的新实验数据表明了2个显奇异夸克隐粲四夸克态Z_(cs)(3985)和Z_(cs)(4003)的存在.在奇异夸克部分,Z_(cs)(3985)和Z_(cs)(4003)的近简并重现了在X(3872)和Zc(3900)间看到的情形.本文指出,在四夸克态图像下,这些Z_(cs)共振态与X(3872)、X(4140)以及Zc(3900)等共振态可以被纳入J^(P)=1^(+)的C宇称相反的2个SU(3)_(f)九重态.作者预言了2个九重态中其他未被发现的共振态的质量.这一分类为四夸克态模型提供了关键证据.Luciano Maiani Antonio D.Polosa Verónica Riquer 2021Science Bulletin2021,66,16:3
9Evaluating character partitioning and molecular models in plastid phylogenomics at low taxonomic levels:A case study using Amphilophium(Bignonieae,Bignoniaceae)显示文摘The accurate analyses of massive amounts of data obtained through next-generation sequencing depend on the selection of appropriate evolutionary models.Many plastid phylogenomic studies typically analyze plastome data as a single partition,or divided by a region,using a concatenate“supergene”approach.The effects of molecular evolutionary models and character partition strategies on plastome-based phylogenies have generally been evaluated at higher taxonomic levels in green plants.Using plastome data from 32 species of Amphilophium,a genus of Neotropical lianas,we explored potential sources of topological incongruence with different plastid genome datasets and approaches.Specifically,we evaluated the effects of compositional heterogeneity,codon usage bias,positive selection,and incomplete lineage sorting as sources of systematic error(i.e.,the recovery of well-supported conflicting topologies).We compared different datasets(e.g.,non-coding regions,exons,and codon-aligned and translated amino acids)using concatenated approaches under site-heterogeneous and site-homogeneous models,as well as multispecies coalescent(MSC)methods.We found incongruences in recovered phylogenetic relationships,which were mainly located in short internodes.The MSC and concatenated approaches recovered similar topologies.The analysis of GC content and codon usage bias indicated higher substitution rates and AT excess at the third codon positions,and we found evidence of positive selection in 3%of amino acid sites.There were no significant differences among species in site biochemical profiles.We argue that the selection of appropriate partition strategies and evolutionary models is important to increase accuracy in phylogenetic relationships,even when using plastome datasets,which is still the primarily used genome in plant phylogenetics.Verônica A.Thode Lúcia G.Lohmann Isabel Sanmartín 2020Journal of Systematics and Evolution2020,58,6:3
10CD99and CD 106(VCAM-1)in human testis显示文摘Aim:The expression of the cytokines Il-2,IL-6,IL-10,IFN-γ and TNF-α and the adhesion proteins CD99 and CD106 was studied in the human testis at the protein level.Methods:The expression of the cytokines and the adhesion proteins was assessed using immunohistochemistry and immunoblotting.Results:None of the cytokines studied was present in the human testis,but CD99 and CD106(VCAM-1) strongly were expressed in all the testes investigated.CD99 was present in the interstitial tissue of the human testis as well as in the Sertoli cells.The identity of the CD99+ interstitial cells is unclear.CD106(VCAM-1) was present in Leydig cells as well as the basal parts of the Sertoli cells in the seminiferous tubules.In immunoblotting,CD99 was demonstrated at molecular ratios of 46-57(kD).This is a novel isoform of the molecule.Conclusion:The human testis produces both CD99 and CD106 and as CD106 mediates cell binding to lymphocytes,it is possible that the human Leydig cells adhere to lymphocytes like the rodent Leydig cells.E. Verjnkorva M. Laato P. Pllnen 2002Asian Journal of Andrology2002,4,4:3
11The new epidemiology of nosocomial bacterial infections in cirrhosis: therapeutical implications显示文摘Juan Acevedo Aníbal Silva Verónica Prado Javier Fernández 2013Hepatology International2013,,1:2
12Initial floristic composition of rehabilitated gullies through bioengineering in the Mixteca Region, Sierra Madre del Sur, Mexico显示文摘Re-vegetation plays a fundamental role for erosion control and plant recovery in lands affected by gully erosion. Bioengineered practices facilitate the gullies rehabilitation. Objectives of the research were: 1) Identify taxonomically the pioneer vegetation on each gully section; 2) Characterize vegetation distribution preferences and 3) Assess structural/functional traits to recognize erosion control key species. Bioengineering was applied in a watershed belonging to Sierra Madre del Sur, at Oaxaca, Mexico, on eight gullies, with local support and minimal investment. 'La Mixteca' is a poor ecological and socio-economic region, comparable to other regions of the world. The Initial Floristic Composition(IFC) inventory is the baseline of the successional process. The transect method was used to determine the colonization of species. Cover abundance of registered species was estimated using the semi-quantitative scale of Braun-Blanquet. This procedure was repeated in five different positions(floor, hillslopes and tops), in the cross section of the gully. Throughcorrespondence analysis and clustering, the distribution of species was analyzed. Adequate responses were obtained in soil retention(quantity) and plant cover(existence and diversity); as measurable indicators of the bioengeneering works efficiency. Occupation of soil by native species from the Tropical Deciduous Forest was favored using live barriers. We detected species guilds with spatial distribution preferences in the gullies cross section. Plant cover characterization includes: native colonizer species, herbaceous, shrubby and trees of the forest community bordering the gully area, with cover abundance and structural/functional traits, useful to protect degraded areas. This spatial occupation process of plants responds to a secondary succession in gullies, where the proposed IFC model is correctly represented through bioengineering. Natural establishment of plants was successful by traits of species such as extensive root system and sexual/vegetative reproduction.Verónica Guadalupe LIRA-CABALLERO Mario Roberto MARTíNEZ-MENEZ Angélica ROMERO-MANZANARES Edmundo GARCíA-MOYA 2018Journal of Mountain Science2018,15,10:2
13Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19.Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral 2021Cellular & Molecular Immunology2021,18,9:2
14Comparison of the antibacterial activity of honey from different provenance against bacteria usually isolated from skin wounds显示文摘Claudia Basualdo Verónica Sgroy Mónica S. Finola Juan M. Marioli 2007Veterinary Microbiology2007,,3:2
15Deposition and transport of functionalized carbon nanotubes in water-saturated sand columns显示文摘Yuan Tian Bin Gao Yu Wang Verónica L. Morales Rafael Mu?oz Carpena Qingguo Huang Liuyan Yang 2012Journal of Hazardous Materials2012,,:2
16Evaluation of various QuEChERS based methods for the analysis of herbicides and other commonly used pesticides in polished rice by LC–MS/MS显示文摘Lucía Pareja Verónica Cesio Horacio Heinzen Amadeo R. Fernández-Alba 2010Talanta2010,,5:2
17Insulin induced translocation of Na^+/K^+-ATPase is decreased in the heart of streptozotocin diabetic rats显示文摘Klara ROSTA Eszter TULASSAY Anna ENZSOLY Katalin RONAI Ambrus SZANTHO Tamas PANDICS Andrea FEKETE Peter MANDL Agota VER 2009Acta Pharmacologica Sinica2009,30,12:2
18Fractional Flow Reserve Versus Angiography for Guiding Percutaneous Coronary Intervention in Patients With Multivessel Coronary Artery Disease显示文摘Nico H.J. Pijls William F. Fearon Pim A.L. Tonino Uwe Siebert Fumiaki Ikeno Bernhard Bornschein Marcel van't Veer Volker Klauss Ganesh Manoharan Thomas Engstr?m Keith G. Oldroyd Peter N. Ver Lee Philip A. MacCarthy Bernard De Bruyne 2010Journal of the American College of Cardiology2010,,3:2
19德国的阿片类依赖替代治疗(英文)显示文摘经过漫长而激烈的争论,德国于1987年首次引进了美沙酮维持治疗。最初,由于入治标准严格,接受治疗的人数很少,但自1990年后接受治疗的人数迅速上升,到2005年底已有61 000人。在德国每位全科医生只要完成了成瘾医学的培训都允许为阿片类成瘾病人开具替代治疗药物。目前德国有2700个全科医生在为阿片类药物成瘾病人开具处方。每位参加维持治疗的病人需接受社会心理治疗。研究结果和实践经验表明,病人从美沙酮维持治疗中获得了实质性的好处,他们的身心健康得到了改善。美沙酮维持治疗的留治率高(65% -85%),对HIV和肝炎的评估和坚持治疗十分重要;在促进病人回归社会方面也是极其重要的因素;在降低药物相关伤害方面如:减少共患疾病、死亡和预防感染性疾病具有重要的作用。有10%的人在长期的治疗过程中戒掉了毒品。虽然丁丙诺啡正在显示其重要性,但是美沙酮仍是主要的替代药物。在农村,参加美沙酮维持治疗仍是难题。虽然一致认为工作是治疗的正性因素,但对病人来说就业机会很少。德国监狱的替代治疗采用不同的准入和治疗模式。准入治疗不协调,参加治疗的人数很少。无论如何,在德国替代治疗在为药物使用者提供的卫生医疗系统中发挥了重要作用。Ingo Ilja MICHELS Heino STVER Ralf GERLACH 2007中国药物依赖性杂志2007,16,3:2
20Urinary neutrophil gelatinase-associated lipocalin as biomarker in the differential diagnosis of impairment of kidney function in cirrhosis显示文摘Claudia Fagundes Marie-No?lle Pépin Mónica Guevara Rogelio Barreto Gregori Casals Elsa Solà Gustavo Pereira Ezequiel Rodríguez Elisabet Garcia Verónica Prado Esteban Poch Wladimiro Jiménez Javier Fernández Vicente Arroyo Pere Ginès 2012Journal of Hepatology2012,,2:2
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