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| 1 | Should dopamine be the first line inotrope in the treatment of neonatal hypotension? Review of the evidence显示文摘AIM: To determine if dopamine is effective in treating neonatal hypotension and safe to use comparing to other inotropes. METHODS: This is a review of evidence on inotropic treatment of neonatal hypotension. Databases searched were MEDLINE and the Cochrane Library, a total of 134 studies were identified. Only studies with high quality evidence(level 1a and b and 2a) were included. After review, only eight studies were included in the final analysis. Pooled risk ratios derived for each outcome [Mantel-Haenzel(M-H) fixed effect] with CI, as reported in the Cochrane reviews were plotted in forest plot form. RESULTS: Eight articles met inclusion criteria, which all included treatment in preterm infants. Dopamine increased mean arterial blood pressure(BP)(n = 163; r = 0.88, 95%CI: 0.76 to 0.94) and systolic BP(n = 142; r = 0.81, 95%CI: 0.42 to 0.94) comparing to placebo. Dopamine has been shown overall to be statistically more effective in increasing BP than dobutamine(n = 251, r = 0.26, 95%CI: 0.20-0.32). However there were no differences in short term outcomes(periventricular leucomalacia, periventricular haemorrhage) and mortality between both drugs. There is no statistical evidence of dopamine being more effective than adrenaline or corticosteroids. There was no difference in morbidity and mortality outcomes when dopamine was compared to hydrocortisone(RR 1.81, 95%CI: 0.18 to 18.39) or adrenaline. CONCLUSION: In preterms, dopamine is the most studied drug, and we suggest it could be used as first line treatment in hypotension. | Sadaf I Bhayat Harsha MS Gowda Michael Eisenhut | 2016 | World Journal of Clinical Pediatrics2016，5，2： | 3 |
| 2 | Does Complete Resection of Melanoma Metastatic to Solid Intra-Abdominal Organs Improve Survival?显示文摘 | Thomas F. Wood MD L. Andrew DiFronzo MD D. Michael Rose MD Philip I. Haigh MD FRCSC Stacey L. Stern MS Leslie Wanek DrPH Richard Essner MD FACS Donald L. Morton MD FACS | 2001 | Annals of Surgical Oncology2001，，8： | 2 |
| 3 | Bridging Locoregional Therapy for Hepatocellular Carcinoma Prior to Liver Transplantation显示文摘 | Jason T. Heckman MD Michael B. deVera MD J. Wallis Marsh MD MBA Paulo Fontes MD Nikhil B. Amesur MD Shane E. Holloway MD Michael Nalesnik MD David A. Geller MD Jennifer L. Steel PhD T. Clark Gamblin MD MS | 2008 | Annals of Surgical Oncology2008，，11： | 2 |
| 4 | Perihepatic Lymph Node Micrometastases Impact Outcome after Partial Hepatectomy for Colorectal Metastases显示文摘 | Joseph J. Bennett MD Carl R. Schmidt MD David S. Klimstra MD Stephen R. Grobmyer MD Nicole M. Ishill MS Michael D'Angelica MD Ronald P. DeMatteo MD Yuman Fong MD Leslie H. Blumgart MD William R. Jarnagin MD | 2008 | Annals of Surgical Oncology2008，，4： | 2 |
| 5 | Informatics competency and development within the US nursing population workforce,a systematic literature review显示文摘 | Michael D Hart MS Bsnrn BC | 2008 | Computers Informatics Nursing2008，26，6： | 1 |
| 6 | Addition of clopidogrel to aspirin and fibrinolytic therapy tbr myocardial infarction with ST-segment elevation显示文摘 | Sabatine MS Cannon CP Michael Gibson C | 2005 | N Engl J Med2005，352，： | 1 |
| 7 | Aggressive surgical and medical management of autosoma recessive polycystic kidney disease (ARPKD) 显示文摘 | Joel MS Mark WB Michael EM | 1993 | Pediatr Urolo1993，42，3： | 1 |
| 8 | The burden of normali ty: A framework for rehabilitation after epilepsy surgery 显示文摘 | Sarah JW Peter FB Michael MS | 2007 | Epilepsia2007，48，9： | 1 |
| 9 | An Aggressive Presentation of Colorectal Cancer With an Atypical Lymphopreliferative Pattern of Meta- static Disease : A Case Report and Review of the Literature 显示文摘 | Sonali MS Michael HR Gabriel KG | 2014 | Clinical Colorectal Cancer2014，13，3： | 1 |
| 10 | Pelli Noise masking reveals channels for second-oreder letters显示文摘 | Michael S Landy MS Pelli DG | 2012 | Version Res2012，46，8： | 1 |
| 11 | Changes in gene expression in response to mechanical strain in human scleral fibroblasts 显示文摘 | Wei Cuia Michael RB Paula MS | 2004 | Experimental Eye Research2004，78，2： | 1 |
| 12 | Addition of clopidogrel to aspirin and fibrinolytic therapy for myocardial infarction with ST-segment elevation显示文摘 | Sabatine MS Cannon CP Michael Gibson C | 2005 | N Engl J Med2005，352，： | 1 |
| 13 | TLR9 is localized in the endoplasmic reticulum prior to stimulation显示文摘 | Cynthia AL Margaret NK Alessandra M ChangWoo L Michael JK David MS | 2004 | J Immunol2004，173，： | 1 |
| 14 | Hypertension in hemodialysis patients显示文摘 | Mahboob Rahman MD MS Michael C. Smith MD | 2001 | Current Hypertension Reports2001，，6： | 1 |
| 15 | Plaque rupture in humans and mice 显示文摘 | Stephen MS Zorina SG Michael ER | 2007 | Arterioscler Thromb Vasc Biol2007，27，4： | 1 |
| 16 | Incidence of and case fa-tality following acute myocardial infarction in aboriginal and non-aboriginal western Australians(2000-2004):A linked data study显示文摘 | Judith MK Frank MS Michael ST | 2010 | Heart Lung and Circulation2010，19，： | 1 |
| 17 | Inhibition of cyclooxygenase-2 and activation of peroxisome proliferator-activated receptor-gamma synergistically induces apoptosis and inhibits growth of human breast cancer cells显示文摘 | Michael MS Badr MZ Badawi AF | 2003 | Int J Mol Med2003，11，6： | 1 |
| 18 | Increased tissue factor expression predicts development of cardiac allograft vasculopathy 显示文摘 | Michael H Guy Pilkington MS Randall C | 2002 | Circulation2002，106，11： | 1 |
| 19 | Liver dysfunction in chronic heart failure : prevalence, characteristics and prognostic significance 显示文摘 | Gerhard P Michael E Christine MS | 2012 | Eur J Clin Invest2012，42，2： | 1 |
| 20 | A natural product ligand of the oxysterol receptor,liver X receptor显示文摘 | Bramlett KS Houck KA Borchert KM Dowless MS Kulanthaivel P Zhang Y Beyer TP Schmidt R Thomas JS Michael LF Barr R Montrose C Eacho PI Cao G Burris TP | | 0，，01： | 1 |
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