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| 1 | Current status of preoperative drainage for distal biliary obstruction显示文摘Preoperative biliary drainage(PBD) was developed to improve obstructive jaundice, which affects a number of organs and physiological mechanisms in patients waiting for surgery. However, its role in patients who will undergo pancreaticoduodenectomy for biliary obstruction remains controversial. This article aims to review the current status of the use of preoperative drainage for distal biliary obstruction. Relevant articles published from 1980 to 2015 were identified by searching MEDLINE and Pub Med using the keywords 'PBD', 'pancreaticoduodenectomy', and 'obstructive jaundice'. Additional papers were identified by a manual search of the references from key articles. Current studies have demonstrated that PBD should not be routinely performed because of the postoperative complications. PBD should only be considered in carefully selected patients, particularly in cases where surgery had to be delayed. PBD may be needed in patients with severe jaundice, concomitant cholangitis, or severe malnutrition. The optimal method of biliary drainage has yet to be confirmed. PBD should be performed by endoscopic routes rather than by percutaneous routes to avoid metastatic tumor seeding. Endoscopic stenting or nasobiliary drainage can be selected. Although more expensive, the use of metallic stents remains a viable option to achieve effective drainage without cholangitis and reintervention. | Harutoshi Sugiyama Toshio Tsuyuguchi Yuji Sakai Rintaro Mikata Shin Yasui Yuto Watanabe Dai Sakamoto Masato Nakamura Reina Sasaki Jun-ichi Senoo Yuko Kusakabe Masahiro Hayashi Osamu Yokosuka | 2015 | World Journal of Hepatology2015，7，18： | 11 |
| 2 | Helicobacter pylori eradication to prevent gastric cancer: underlying molecular and cellular mechanisms显示文摘众多的细胞、分子的事件在胃的癌症的开发被描述了。在这篇文章,我们 Helicobacter pylori (H pylori ) 的 overviewed 角色一些在胃的致癌作用的重要事件上的感染并且讨论了这些细胞、分子的事件是否在感染的痊愈以后是可逆的。有几个细菌的部件,影响胃的致癌作用的胃的上皮的动力学和提升。细菌也增加基因不稳定性和变化的风险由于没有并且另外的反应的氧种类。肿瘤的渐成说 silencing 压制或象 RUNX3 那样的基因可以与肠的组织变形改变那些的胃腺的显型变化的频率。象生长因素, cytokines 和 COX-2 的增加的表示那样的主机因素也在 H pylori 积极的题目在非癌的织物被报导了。大多数上述现象在感染的痊愈以后被颠倒,是引人注目的。然而,他们的一些包括在 COX-2 的表示上继续存在并且可以为致癌作用增加风险在甚至在成功的 H pylori 根除以后遇见了无形或发育异常的的粘膜。因此, H pylori 根除不能完全为胃的致癌作用废除风险。胃的癌症取决于预定和目标人口的在压制的感染的痊愈的效率,和保证推进调查。 | Shingo Tsuji Masahiko Tsujii Hiroaki Murata Tsutomu Nishida Masato Komori Masakazu Yasumaru Shuji Ishii Yoshiaki Sasayama Sunao Kawano Norio Hayashi | 2006 | World Journal of Gastroenterology2006，12，11： | 7 |
| 3 | Prevention of post-endoscopic retrograde cholangiopancreatography pancreatitis by pancreatic duct stenting using a loop-tipped guidewire显示文摘AIM: To examine whether it is possible to prevent the occurrence of post-endoscopic retrograde cholangiopancreatography(ERCP) pancreatitis in patients experiencing difficulties with selective biliary duct cannulation by pancreatic duct stenting using a looptipped guidewire.METHODS: Procedure success rate, frequency of unintended insertion of the guidewire into side branches of the pancreatic duct, and incidence of procedural accidents were examined using a loop-tipped guidewire(Group A, 20 patients), and a conventional straighttype guidewire(Group B, 20 patients).RESULTS: The success rate of the procedure was 100% in both groups. Unintended insertion of the guidewire into a side branch of the pancreatic duct occurred 0.056 ± 0.23(0-1) times in Group A and 2.3 ±1.84(0-5) times in Group B; thus, unintended insertion of the guidewire into a side branch of the pancreatic duct was seen significantly less frequently in Group A. There were no procedural accidents in Group A, whereas pancreatitis occurred in one Group B patient; however, the difference between the two groups was not statistically significant. The serum amylase level after ERCP was 257.15 ± 136.4(88-628) IU/L in Group A, and 552.05 ± 534.57(101-2389) IU/L in Group B, showing a significantly lower value in Group A. Hyperamylasemia was found in two patients(10%) in Group A, and nine(45%) in Group B, showing a significantly lower value in Group A.CONCLUSION: The results suggest that in patients who experience difficulties with biliary cannulation, the use of a loop-tipped guidewire for pancreatic duct stenting may assist with the prevention of post-ERCP pancreatitis, and thereby to a reduction of the risk of post-ERCP pancreatitis or hyperamylasemia. | Yuji Sakai Toshio Tsuyuguchi Harutoshi Sugiyama Masahiro Hayashi Jun-ichi Senoo Reina Sasaki Yuko Kusakabe Masato Nakamura Shin Yasui Rintaro Mikata Masaru Miyazaki Osamu Yokosuka | 2016 | World Journal of Clinical Cases2016，4，8： | 5 |
| 4 | Xyloglucan for Generating Tensile Stress to Bend Tree Stem显示文摘响应环境变化,被子植物树由形成紧张木头把他们的茎弄弯,它由充满纤维素的 G 组成(凝胶状) 在纤维房间的墙中的层并且在第二等的木部产生反常张力的应力。我们生产了转基因的白杨植物 overexpressing 在房间墙中减少每特定的多糖,,的几 endoglycanases 第二等的木部由主要、第二等的墙层组成。当水平地放了时,转基因的白杨 overexpressing xyloglucanase 的茎的基础区域不能独自在木部的紧张方面由于低紧张向上弯曲。在野类型的植物, xyloglucan 在多重 layering 期间在 G 层的内部表面被发现。在 situ xyloglucan endotransglucosylase ( XET ),活动证明整个 xyloglucan 的加入,潜在地因为墙紧缩,在内部表面层 S1 和 S2 开始了并且在整个G层开发被保留,当为墙松开的 xyloglucan heptasaccharide ( XXXG )的加入发生在膨胀地区的主要的墙中时。我们建议 xyloglucan 网络被 XET 增强形成在墙界限之间的一个进一步的连接并且分泌了 xyloglucans 以便承受在纤维素 G 层 microfibrils 以内创造的张力的压力。 | Kei'ichi Baba Yong Woo Park Tomomi Kaku Rumi Kaida Miyuki Takeuchi Masato Yoshida Yoshihiro Hosoo Yasuhisa Ojio Takashi Okuyama Toru Taniguchi Yasunori Ohmiya Teiji Kondo Ziv Shani Oded Shoseyov Tatsuya Awano Satoshi Serada Naoko Norioka Shigemi Norioka Takahisa Hayashi | 2009 | Molecular Plant2009，2，5： | 4 |
| 5 | Intraductal papillary neoplasm of the bile duct accompanying biliary mixed adenoneuroendocrine carcinoma显示文摘We present the first case of an intraductal papillary neoplasm of the bile duct(IPNB) accompanying a mixed adenoneuroendocrine carcinoma(MANEC).A 74-yearold woman presented with fever of unknown cause.Laboratory data revealed jaundice and liver injury.Contrast-enhanced computed tomography revealed a 20 mm polypoid tumor in the dilated distal bile duct,which exhibited early enhancement and papillary growth.Upper gastrointestinal endoscopy revealed mucus production from the papilla of Vater,characterized by its protruding and dilated orifice.Endoscopic ultrasonography visualized the polypoid tumor in the distal bile duct,but no invasive region was suggested by diagnostic imaging.Therefore,the initial diagnosis was IPNB.After endoscopic nasobiliary drainage,a pylorus-preserving pancreaticoduodenectomy was performed.Pathological examination of the resected bile duct revealed papillary proliferation of biliary-type cells with nuclear atypia,indicating pancreaticobiliary-type IPNB.In addition,solid portions comprised of tumor cells with characteristic salt-and-pepper nuclei were evident.Immunohistochemistry revealed expression of the neuroendocrine marker synaptophysin in this solid component,diagnosing it as a neuroendocrine tumor(NET).Furthermore,the MIB-1 proliferation index of NET was higher than that of IPNB,and microinvasion of the NET component was found,indicating neuroendocrine carcinoma(NET G3).This unique case of MANEC,comprising IPNB and NET,provides insight into the pathogenesis of biliary NET. | Ichiro Onishi Hirohisa Kitagawa Kenichi Harada Syogo Maruzen Seisyo Sakai Isamu Makino Hironori Hayashi Hisatoshi Nakagawara Hidehiro Tajima Hiroyuki Takamura Takashi Tani Masato Kayahara Hiroko Ikeda Tetsuo Ohta Yasuni Nakanuma | 2013 | World Journal of Gastroenterology2013，19，20： | 2 |
| 6 | Gastric small cell carcinoma with marked response to neoadjuvant chemotherapy显示文摘 | Yasuhiro Nakamura Setsuya Otani Michiro Otaka Tomoyuki Shimada Satsuki Takahashi Masahiro Saito Tohru Takahashi Masahumi Komatsu Toshie Suzuki Shunji Okubo Masato Hayashi Hironobu Sasano | 2005 | International Journal of Clinical Oncology2005，，5： | 1 |
| 7 | Oxidation Protective Silicide Coating on Mo-Si-B Alloys显示文摘 | Taisuke Hayashi Masato Yokobayashi | 2005 | Metallurgical and Materials Transactions A2005，36，： | 1 |
| 8 | Plasma oxidized low-density lipoprotein as a prognostic predictor in patients with chronic congestive heart failure显示文摘 | Takashi Tsutsui Takayoshi Tsutamoto Atsuyuki Wada Keiko Maeda Naoko Mabuchi Masaru Hayashi Masato Ohnishi Masahiko Kinoshita | 2002 | Journal of the American College of Cardiology2002，，6： | 1 |
| 9 | Oscillatory epidemic prevalence in growing scale-free networks显示文摘 | Masato Minoura Jun Matsukubo | 2004 | Physical Review E2004，69，01： | 1 |
| 10 | Respiratory Epithelial Adenomatoid Hamartoma in the Nasal Cavity显示文摘 | Ryo Endo Hideki Matsuda Masato Takahashi Masamichi Hara Hayashi Inaba Mamoru Tsukuda | 2002 | Acta Oto-Laryngologica2002，，4： | 1 |
| 11 | Preparation of polymer particles covered with ferrite powder by suspension polymerization: effect of wettability of powder on composite particle size distribution显示文摘 | Masato Tanaka Kenji Hayashi | 1990 | Journal of Materials Science1990，，25： | 1 |
| 12 | Phytoplankton dynamics in the East China Sea in spring and summer as revealed by HPLC-derived pigment sinatures 显示文摘 | Ken Furuya Masato Hayashi Yasushi Yabushita | 1999 | Deep-Sea Research Ⅱ1999，50，2003： | 1 |
| 13 | Relationship Between Renal Function and Plasma Brain Natriuretic Peptide in Patients With Heart Failure显示文摘 | Takayoshi Tsutamoto Atsuyuki Wada Hiroshi Sakai Chitose Ishikawa Toshinari Tanaka Masaru Hayashi Masanori Fujii Takashi Yamamoto Tomohiro Dohke Masato Ohnishi Hiroyuki Takashima Masahiko Kinoshita Minoru Horie | 2006 | Journal of the American College of Cardiology2006，，3： | 1 |
| 14 | Associations among pain catastrophizing, muscle strength, and physical performance after total knee and hip arthroplasty显示文摘AIM To investigate whether reductions in pain catastrophizing associated with physical performance in the early period after total knee arthroplasty(TKA) or total hip arthroplasty(THA).METHODS The study group of 46 participants underwent TKA or THA. The participants were evaluated within 7d before the operation and at 14d afterwards. Physical performance was measured by the Timed Up and Go(TUG) test, and 10-m gait time was measured at comfortable and maximum speeds. They rated their knee or hip pain using a visual analog scale(VAS) for daily life activities. Psychological characteristics were measured by the Pain Catastrophizing Scale(PCS). Physical characteristics were measured by isometric muscle strength of knee extensors and hip abductors on the operated side. The variables of percent changes between pre-and postoperation were calculated by dividing post-operation score by pre-operation score.RESULTS Postoperative VAS and PCS were better than preoperative for both TKA and THA. Postoperative physical performance and muscle strength were poorer than preoperative for both TKA and THA. The percent change in physical performance showed no correlation with preoperative variables. In TKA patients, the percent change of PCS showed correlation with percent change of TUG(P = 0.016), 10-m gait time at comfortable speeds(P = 0.003), and 10-m gait time at maximum speeds(P = 0.042). The percent change of muscle strength showed partial correlation with physical performances.The percent change of VAS showed no correlation with physical performances. On the other hand, in THA patients, the percent change of hip abductor strength showed correlation with percent change of TUG(P =0.047), 10-m gait time at comfortable speeds(P = 0.001),and 10-m gait time at maximum speeds(P = 0.021). The percent change of knee extensor strength showed partial correlation with physical performances. The percent change of VAS and PCS showed no correlation with physical performances.CONCLUSION Changes in pain catastrophizing significantly associated with changes in physical performance in the early period after TKA. It contributes to future postoperative rehabilitation of arthroplasty. | Kazuhiro Hayashi Masato Kako Kentaro Suzuki Keiko Hattori Saori Fukuyasu Koji Sato Izumi Kadono Tadahiro Sakai Yukiharu Hasegawa Yoshihiro Nishida | 2017 | World Journal of Orthopedics2017，8，4： | 1 |
| 15 | A genome-based approach to create a minimally mutated Corynebacterium glutamicum strain for efficient L-lysine production显示文摘 | Masato Ikeda Junko Ohnishi Mikiro Hayashi | 2006 | J Ind Microbiol Biotechnol2006，33，： | 1 |
| 16 | Evolution kinetics and microstructure of MoSiz and MosSi3 surface layers on two-phase Mo-9Si-18B alloy during pack-cementation and high-temperature oxidation 显示文摘 | KAZUHIRO Ito TAISUKE Hayashi MASATO Yokobayashi | 2004 | Intermetallics2004，12，4： | 1 |
| 17 | Bone Repair by Transplantation of hTERT-Immortalized Human Mesenchymal Stem Cells in Mice显示文摘 | Hiroyuki Nakahara Haruo Misawa Takahiro Hayashi Eisaku Kondo Takeshi Yuasa Yasuhiro Kubota Masayuki Seita Hironobu Kawamoto Wael A. R. A. Hassan Reham A. R. A. Hassan Shahid M. Javed Masato Tanaka Hirosuke Endo Hirofumi Noguchi Shinichi Matsumoto Katsuyos | 2009 | Transplantation2009，，3： | 1 |
| 18 | Evolution kinetics and microstructure of MoSi2 and Mo5Si3 surface layers on two-phase Mo-9Si-18B alloy during pack-cementation and high-temperature oxidation显示文摘 | KAZUHIRO ITO TAISUKE HAYASHI MASATO YOKOBAYASHI | 2004 | Intermetallics2004，12，： | 1 |
| 19 | Angiotensin II type 1 receptor antagonist decreases plasma levels of tumor necrosis factor alpha, interleukin-6 and soluble adhesion molecules in patients with chronic heart failure显示文摘 | Takayoshi Tsutamoto Atsuyuki Wada Keiko Maeda Naoko Mabuchi Masaru Hayashi Takashi Tsutsui Masato Ohnishi Masahide Sawaki Masanori Fujii Takehiro Matsumoto Masahiko Kinoshita | 2000 | Journal of the American College of Cardiology2000，，3： | 1 |
| 20 | Magnetic thin film of eobah nnocrystals encapsulated in graphite-- like carhon显示文摘 | Takayoshi Hayashi Shigeru Hirono Masato Tomita | 1996 | Nature1996，381，： | 1 |
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