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| 1 | High relative fat-free mass is important for maintaining serum albumin levels in patients with compensated liver cirrhosis显示文摘AIM: In patients with liver cirrhosis, hypoalbuminemia causes edema and ascites, and a reduction in the quality of life. Since musculature is catabolized to supply amino acids for albumin synthesis in malnutritional cirrhotic patients, muscular volume is hypothesized to play an important role in albumin production. Therefore, we investigated the correlation between serum albumin levels and the fat-free mass (FFM) in cirrhotic patients.METHODS: Fifty-seven patients (26 males and 31 females)with compensated liver cirrhosis were evaluated. Patients with edema or ascites were excluded from the study.Healthy volunteers (n = 104; 48 males and 56 females)were also evaluated as controls. FFM was measured using 5-500 kHz multifrequency bioelectric impedance analysis.To minimize the difference in FFM distribution between males and females, we introduced a new marker, relative FFM (rFFM), which represents the ratio of FFM in a patient relative to that in a volunteer of the same height. Following FFM measurement, the serum albumin levels of patients were assayed monthly.RESULTS: In patients with active cirrhosis (alanine aminotransaminase [ALT] >50 U/L), both albumin (the difference between maximum and minimum levels) and the standard deviation of albumin levels (SD-albumin) during the observation period showed a significant correlation with rFFM. Multiple linear regression analysis using variables such as rFFM, platelet number, and serum cholesterol levels,choline esterase, albumin, bilirubin, and ALT revealed that rFFM and ALT were significant and independent factors that influenced albumin or SD-albumin in cirrhotic patients.CONCLUSION: Our results indicate that cirrhotic patients with high rFFM showed less of a decrease in albumin levels, and that the muscle volume is one of the most important factors for maintaining serum albumins level in active cirrhosis. Exercise and protein-rich nutrition at the early stage of liver cirrhosis may be advisable for maintaining or increasing muscular volume. | Kazuhiro Kotoh Makoto Nakamuta Marie Fukushima Chitose Matsuzaki Munechika Enjoji Hironori Sakai Hajime Nawata | 2005 | World Journal of Gastroenterology2005，11，9： | 4 |
| 2 | Light-Regulated Plant Growth and Development显示文摘 | Chitose Kami Séverine Lorrain Patricia Hornitschek Christian Fankhauser | 2010 | Current Topics in Developmental Biology2010，，： | 2 |
| 3 | Effect of a hydrophilic and a hydrophobic statin on cardiac salvage after ST-elevated acute myocardial infarction – A pilot study显示文摘 | Tadasuke Chitose Seigo Sugiyama Kenji Sakamoto Hideki Shimomura Takuro Yamashita Jun Hokamaki Ryusuke Tsunoda Shinya Shiraishi Yasuyuki Yamashita Hisao Ogawa | 2014 | Atherosclerosis2014，，1： | 1 |
| 4 | Development of solid oxide fuel cell stack using lanthanum gallate-based oxide as an electrolyte 显示文摘 | YAMADA T CHITOSE N ETOU H | 2007 | Ceram Eng Sci Proc2007，2，4： | 1 |
| 5 | Long-term postoperative vocal function after thyroplasty type I and fat injection laryngoplasty显示文摘 | UMENOH CHITOSE S SATO K | 2012 | Ann Otol Rhinol Laryngol2012，12，： | 1 |
| 6 | Specifying recon-figurable control flow for open architecture controller 显示文摘 | CHITOS WASHBURNJ WANGS | 1998 | Proceedings 1998 Japan-USA Symposium on Flexible Auto-mation1998，7，2： | 1 |
| 7 | Four cases of acute epiglottitis witha peritonsillar abscess显示文摘 | Ito K Chitose H Koganemaru M | 2011 | Auris Nasus Larynx2011，38，2： | 1 |
| 8 | Plasma C-reactive protein is an independent prognostic predictor in patients with dilated cardiomyopathy显示文摘 | Ishikawa Chitose Tsutamoto Takayoshi Sakai Hiroshi Ohno Keijin Horie Minoru | 2004 | Journal of Cardiac Failure2004，，5： | 1 |
| 9 | Evaluation of basal media for micropropagation of four highbush blueberry cultivars显示文摘 | Takuya Tetsumura Yasuyo Matsumoto Makiko Sato Chitose Honsho Kensuke Yamashita Haruki Komatsu Yasuhiro Sugimoto Hisato Kunitake | 2008 | Scientia Horticulturae2008，119，： | 1 |
| 10 | Sequence analyses of the ITS regions and the matK gene for determining phylogenetic relationships of Diospyros kaki (persimmon) with other wild Diospyros (Ebenaceae) species显示文摘 | Keizo Yonemori Chitose Honsho Shinya Kanzaki Hitofumi Ino Ayako Ikegami Akira Kitajima Akira Sugiura Dan E. Parfitt | 2008 | Tree Genetics & Genomes2008，，2： | 1 |
| 11 | Relationship of European persimmon (Diospyros kaki Thunb.) cultivars to Asian cultivars, characterized using AFLPs显示文摘 | Keizo Yonemori Chitose Honsho Akira Kitajima Malli Aradhya Edgardo Giordani Elvio Bellini Dan E. Parfitt | 2008 | Genetic Resources and Crop Evolution2008，，1： | 1 |
| 12 | Patterns of laryngopharyngeal and gastroesophageal reflux 显示文摘 | Sato K Umeno H Chitose S | 2009 | J Laryngol Otol Suppl2009，31，： | 1 |
| 13 | Clinical outcomes following coronary stenting in Japanese patients treated with and without proton pump inhibitor 显示文摘 | Chitose T Hokimoto S Oshima S | 2012 | Circ J2012，76，1： | 1 |
| 14 | Immunological re- sponses against human papilloma virus and human papilloma virus induced laryngeal cancer 显示文摘 | Chitose S Sakazaki T Ono T | 2010 | Laryngol Otol2010，124，6： | 1 |
| 15 | Impact of CYP2C19 polymo-phism on residual platelet reactivity in patients with coronary heart dis- ease during antiplatelet therapy显示文摘 | Yamamoto K Hokimoto S Chitose T | 2011 | J Cardio12011，57，： | 1 |
| 16 | Four cases of acute epiglottitis with a peritonsillar abscess 显示文摘 | ITO K CHITOSE H KOGANEMARU M | 2011 | Auris Nasus Larynx2011，38，： | 1 |
| 17 | Effect of a hydro- philic and a hydrophot)ic statin on cardiac salvage after ST-ele- vated acute myocardial infarction a pilot study显示文摘 | Chitose T Sugiyama S Sakamoto K | 2014 | Atherosclero- sis2014，237，1： | 1 |
| 18 | Inhibition of Aldosterone and Endothelin-1 by Carperitide Was Attenuated With More Than 1 Week of Infusion in Patients With Congestive Heart Failure显示文摘 | Chitose Ishikawa Takayoshi Tsutamoto Atsuyuki Wada Masanori Fujii Keijin Ohno Hiroshi Sakai Takashi Yamamoto Minoru Horie | 2005 | Journal of Cardiovascular Pharmacology2005，，4： | 1 |
| 19 | Analysis of voice function following autoogous:Fat injection for vocal fold paralysis显示文摘 | Umeno H Shrouzu H Chitoses H | 2005 | Otolaryngol Head Neeksurg2005，132，： | 1 |
| 20 | Formation of direct mutagen MX in water and induction of toxic effects显示文摘 | Naohide K Chitose S Kayoko S | 2000 | Environ Mutagen Res2000，22，： | 1 |
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