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| 1 | Clinical and radiological feature of lymphoepithelial cyst of the pancreas显示文摘A lymphoepithelial cyst(LEC)of the pancreas is a rare benign lesion.Because patients with LEC of the pancreas have a good prognosis,it is important that these lesions are accurately differentiated from other more aggressive pancreatic neoplasms for an appropriate treatment strategy.Previous studies have reported that a definitive diagnosis of LEC often cannot be obtained based solely on the findings of preoperative imaging(e.g.,Computed tomography or Magnetic resonance imaging).In this study,we reviewed four cases of pancreatic LECs to investigate the feature of LECs.We reviewed these cases with regard to symptoms,imaging findings,surgical procedures,and other clinical factors.We found that LEC was associated with unique characteristics on imaging findings.A preoperative diagnosisof LEC may be possible by comprehensively evaluating its clinical and imaging findings. | Hirofumi Terakawa Isamu Makino Hisatoshi Nakagawara Tomoharu Miyashita Hidehiro Tajima Hirohisa Kitagawa Takashi Fujimura Dai Inoue Kazuto Kozaka Toshifumi Gabata Tetsuo Ohta | 2014 | World Journal of Gastroenterology2014，20，45： | 4 |
| 2 | A case report of anaplastic carcinoma of the pancreas with remarkable intraductal tumor growth into the main pancreatic duct显示文摘We herein report a case of anaplastic carcinoma of the pancreas with remarkable intraductal tumor growth into the main pancreatic duct.A 76-year-old male was referred to our hospital for treatment of a pancreatic tumor.Preoperative examinations revealed a poorly defined tumor in the main pancreatic duct in the body of the pancreas,accompanied with severe dilatation of the main pancreatic duct,which was diagnosed as an intraductal papillary-mucinous neoplasm.We performed distal pancreatectomy and splenectomy.The pathological examination revealed that the tumor consisted of a mixture of anaplastic carcinoma(giant cell type)and adenocarcinoma in the pancreas.There was a papillary projecting tumor composed of anaplastic carcinoma in the dilated main pancreatic duct.The patient is now receiving chemotherapy because liver metastasis was detected 12 mo after surgery.In this case,we could observe a remarkable intraductal tumor growth into the main pancreatic duct.We also discuss the pathogenesis and characteristics of this rare tumor with specific tumor growth. | Mitsuyoshi Okazaki Isamu Makino Hirohisa Kitagawa Shinichi Nakanuma Hironori Hayashi Hisatoshi Nakagawara Tomoharu Miyashita Hidehiro Tajima Hiroyuki Takamura Tetsuo Ohta | 2014 | World Journal of Gastroenterology2014，20，3： | 2 |
| 3 | Intraductal papillary neoplasm of the bile duct accompanying biliary mixed adenoneuroendocrine carcinoma显示文摘We present the first case of an intraductal papillary neoplasm of the bile duct(IPNB) accompanying a mixed adenoneuroendocrine carcinoma(MANEC).A 74-yearold woman presented with fever of unknown cause.Laboratory data revealed jaundice and liver injury.Contrast-enhanced computed tomography revealed a 20 mm polypoid tumor in the dilated distal bile duct,which exhibited early enhancement and papillary growth.Upper gastrointestinal endoscopy revealed mucus production from the papilla of Vater,characterized by its protruding and dilated orifice.Endoscopic ultrasonography visualized the polypoid tumor in the distal bile duct,but no invasive region was suggested by diagnostic imaging.Therefore,the initial diagnosis was IPNB.After endoscopic nasobiliary drainage,a pylorus-preserving pancreaticoduodenectomy was performed.Pathological examination of the resected bile duct revealed papillary proliferation of biliary-type cells with nuclear atypia,indicating pancreaticobiliary-type IPNB.In addition,solid portions comprised of tumor cells with characteristic salt-and-pepper nuclei were evident.Immunohistochemistry revealed expression of the neuroendocrine marker synaptophysin in this solid component,diagnosing it as a neuroendocrine tumor(NET).Furthermore,the MIB-1 proliferation index of NET was higher than that of IPNB,and microinvasion of the NET component was found,indicating neuroendocrine carcinoma(NET G3).This unique case of MANEC,comprising IPNB and NET,provides insight into the pathogenesis of biliary NET. | Ichiro Onishi Hirohisa Kitagawa Kenichi Harada Syogo Maruzen Seisyo Sakai Isamu Makino Hironori Hayashi Hisatoshi Nakagawara Hidehiro Tajima Hiroyuki Takamura Takashi Tani Masato Kayahara Hiroko Ikeda Tetsuo Ohta Yasuni Nakanuma | 2013 | World Journal of Gastroenterology2013，19，20： | 2 |
| 4 | Neoadjuvant chemotherapy with gemcitabine for pancreatic cancer increasesin situ expression of the apoptosis marker M30 and stem cell marker CD44显示文摘 | Hidehiro Tajima Tetsuo Ohta Hirohisa Kitagawa Koichi Okamoto Seisho Sakai Jun Kinoshita Isamu Makino Hiroyuki Furukawa Hironori Hayashi Keishi Nakamura Katsunobu Oyama Masafumi Inokuchi Hisatoshi Nakagawara Hideto Fujita Hiroyuki Takamura Itasu Ninomiya S | 2012 | Oncology Letters2012，，： | 2 |
| 5 | The role of human peritoneal mesothelial cells in the fibrosis and progressionof gastric cancer显示文摘 | Tomoya Tsukada Sachio Fushida Shinichi Harada Yasumichi Yagi Jun Kinoshita Katsunobu Oyama Hidehiro Tajima Hideto Fujita Itasu Ninomiya Takashi Fujimura Tetsuo Ohta | 2012 | International Journal of Oncology2012，，2： | 1 |
| 6 | The management of a remnant pancreatic stump for preventing the development of postoperative pancreatic fistulas after distal pancreatectomy: current evidence and our strategy显示文摘 | Isamu Makino Hirohisa Kitagawa Hisatoshi Nakagawara Hidehiro Tajima Itasu Ninomiya Sachio Fushida Takashi Fujimura Tetsuo Ohta | 2013 | Surgery Today2013，，6： | 1 |
| 7 | Low?dose paclitaxel inhibits the induction of epidermal?mesenchymaltransition in the human cholangiocarcinoma CCKS?1 cell line显示文摘 | Atsushi Hirose Hidehiro Tajima Tetsuo Ohta Tomoya Tsukada Koichi Okamoto Shinichi Nakanuma Seisho Sakai Jun Kinoshita Isamu Makino Hiroyuki Furukawa Hironori Hayashi Keishi Nakamura Katsunobu Oyama Masafumi Inokuchi Hisatoshi Nakagawara Tomoharu Miyashita | 2013 | Oncology Letters2013，，4： | 1 |
| 8 | Sivelestat Sodium Hydrate Inhibits Neutrophil Migration to the Vessel Wall and Suppresses Hepatic Ischemia–Reperfusion Injury显示文摘 | Seisho Sakai Hidehiro Tajima Tomoharu Miyashita Shin-ichi Nakanuma Isamu Makino Hironori Hayashi Hisatoshi Nakagawara Hirohisa Kitagawa Sachio Fushida Takashi Fujimura Hidehito Saito Seiichi Munesue Yasuhiko Yamamoto Tetsuo Ohta | 2014 | Digestive Diseases and Sciences2014，，4： | 1 |
| 9 | Pioglitazone inhibits the proliferation and metastasis of human pancreaticcancer cells显示文摘 | Itasu Ninomiya Keisuke Yamazaki Katsunobu Oyama Hironori Hayashi Hidehiro Tajima Hirohisa Kitagawa Sachio Fushida Takashi Fujimura Tetsuo Ohta | 2014 | Oncology Letters2014，，6： | 1 |
| 10 | A case of pancreatic schwannoma - The features in imaging studies compared with its pathological findings: Report of a case显示文摘 | Yoshinao Ohbatake Isamu Makino Hirohisa Kitagawa Shinichi Nakanuma Hironori Hayashi Hisatoshi Nakagawara Tomoharu Miyashita Hidehiro Tajima Hiroyuki Takamura Itasu Ninomiya Sachio Fushida Takashi Fujimura Tetsuo Ohta | 2014 | Clinical Journal of Gastroenterology2014，，3： | 1 |
| 11 | Spontaneous clearance of Helicobacter pylori after pylorus-preservinggastrectomy for gastric cancer显示文摘 | Tomoharu Miyashita Koichi Miwa Masafumi Inokuchi Hisatoshi Nakagawara Hidehiro Tajima Hiroyuki Takamura Itasu Ninomiya Hirohisa Kitagawa Sachio Fushida Takashi Fujimura Takanori Hattori Tetsuo Ohta | 2013 | Oncology Reports2013，，1： | 1 |
| 12 | Role of Nodal Involvement and the Periductal Soft-Tissue Margin in Middle and Distal Bile Duct Cancer显示文摘 | Masato Kayahara Takukazu Nagakawa Tetsuo Ohta Hirohisa Kitagawa Hidehiro Tajima Koichi Miwa | 1999 | Annals of Surgery1999，，1： | 1 |
| 13 | Hepatic arterial infusion chemotherapy with gemcitabine and 5?fluorouracilor oral S?1 improves the prognosis of patients with postoperative liver metastasesfrom pancreatic cancer显示文摘 | Hidehiro Tajima Hirohisa Kitagawa Tomoya Tsukada Koichi Okamoto Shin?Ichi Nakanuma Seisho Sakai Isamu Makino Hiroyuki Furukawa Hironori Hayashi Katsunobu Oyama Masafumi Inokuchi Hisatoshi Nakagawara Tomoharu Miyashita Hiroshi Itoh Hideto Fujita Hiroyuki T | 2013 | Molecular and Clinical Oncology2013，，5： | 1 |
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