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| 1 | Sclerosing epithelioid fibrosarcoma of the liver infiltrating the inferior vena cava显示文摘Sclerosing epithelioid fibrosarcoma (SEF) is a rare and distinct variant of fibrosarcoma, composed of epithelioid tumor cells arranged in strands, nests, cords, or sheets embedded within a sclerotic collagenous matrix. We report a 39-year-old man with SEF of the liver, which infiltrated the inferior vena cava (IVC). The SEF of the liver was successfully resected, and the infiltrated IVC was also removed together with the liver tumor. Histopathological examination of the tumor showed typical histopathology of SEF. Immunohistochemically, the tumor was positive for vimentin. Recurrence was noted 7 mo after surgery. After chemotherapy, the recurrent tumor was resected surgically, and histopathological examination showed similar findingsto those of the primary tumor. To our knowledge, this is the first report of SEF of the liver with tumor invasion of the IVC. | Yoshito Tomimaru Hiroaki Nagano Shigeru Marubashi Shogo Kobayashi Hidetoshi Eguchi Yutaka Takeda Masahiro Tanemura Toru Kitagawa Koji Umeshita Nobuyuki Hashimoto Hideki Yoshikawa Kenichi Wakasa Yuichiro Doki Masaki Mori | 2009 | World Journal of Gastroenterology2009，15，33： | 5 |
| 2 | Incomplete transformations of Pb to pyromorphite by phosphate-induced immobilization investigated by X-ray absorption fine structure (XAFS) spectroscopy显示文摘 | Yohey Hashimoto Masaki Takaoka Kazuyuki Oshita Hajime Tanida | 2009 | Chemosphere2009，，5： | 2 |
| 3 | Characterization of Ca^2+ channels involved in ET-1 -induced transactivation of EGF receptors显示文摘 | KAWANABE Y HASHIMOTO N MASAKI T | 2002 | Am J Physiol Heart Circ Physiol2002，283，6： | 1 |
| 4 | Endoscopic ultrasound-guided fine-needle aspiration of solid pancreatic masses with rapid on-site cytological evaluation by endosonographers without attendance of cytopathologists显示文摘 | Takuto Hikichi Atsushi Irisawa Manoop S. Bhutani Tadayuki Takagi Goro Shibukawa Go Yamamoto Takeru Wakatsuki Hidemichi Imamura Yuta Takahashi Ai Sato Masaki Sato Tsunehiko Ikeda Yuko Hashimoto Kazuhiro Tasaki Kazuo Watanabe Hiromasa Ohira Katsutoshi Obara | 2009 | Journal of Gastroenterology2009，，4： | 1 |
| 5 | Anomalous Vertebral Artery at the Extraosseous and Intraosseous Regions of the Craniovertebral Junction: Analysis by Three-Dimensional Computed Tomography Angiography显示文摘 | Masashi Yamazaki Masao Koda Masa-aki Aramomi Mitsuhiro Hashimoto Yutaka Masaki Akihiko Okawa | 2005 | Spine2005，，21： | 1 |
| 6 | Involvement of epidermal growth factor receptor-protein tyrosine kinase transactivation in endothelin-l-induced vascular contraction 显示文摘 | Kawanabe Y Masaki T Hashimoto N | 2004 | J Neurosurg2004，100，6： | 1 |
| 7 | Administration of Ex Vivo-expanded Bone Marrow-derived Endothelial Progenitor Cells Attenuates Focal Cerebral Ischemia-reperfusion Injury in Rats显示文摘 | Tsuyoshi Ohta Ken-ichiro Kikuta Hirotoshi Imamura Yasushi Takagi Masaki Nishimura Yoshiki Arakawa Nobuo Hashimoto Kazuhiko Nozaki | 2006 | Neurosurgery2006，，3： | 1 |
| 8 | High Twist expression is involved in infiltrative endometrial cancer and affects patient survival显示文摘 | Satoru Kyo Junko Sakaguchi Satoshi Ohno Yasunari Mizumoto Yoshiko Maida Manabu Hashimoto Mitsuhiro Nakamura Masahiro Takakura Miki Nakajima Kenkichi Masutomi Masaki Inoue | 2006 | Human Pathology2006，，4： | 1 |
| 9 | Involvements of voltageindependent Ca^2+ channels and phosphoinositide 3-kinase in endothelin -1-induced Pyk2 tyrosine phosphorylation显示文摘 | Kawanabe Y Hashimoto N Masaki T | 2003 | Mol Pharmacol2003，63，4： | 1 |
| 10 | Involvement of epidermal growth factor receptor-protein tymsine kinase transactivation in endothelin- 1-induced vascular contraction 显示文摘 | Kawanabe Y Masaki T Hashimoto N | 2004 | J Neurosurg2004，100，6： | 1 |
| 11 | Involvement of epidermal growth factor receptor-protein tyrosine kinase transactivation in en- dothelin-l-induced vascular contraction 显示文摘 | Kawanabe Y Masaki T Hashimoto N | 2004 | J Neurosurg2004，100，： | 1 |
| 12 | Ca(2+) influx through nonselective cation channels plays an essential role in endothelin-1-induced mitogenesis in C6 glioma cells显示文摘 | Kawanabe Y Hashimoto N Masaki T | 2001 | Neuropharmacology2001，41，3： | 1 |
| 13 | Anti-High-Mobility Group Box Chromosomal Protein 1 Antibodies Improve Survival of Rats with Sepsis显示文摘 | Koichi Suda Yuko Kitagawa Soji Ozawa Yoshiro Saikawa Masakazu Ueda Masahito Ebina Shingo Yamada Satoru Hashimoto Shinji Fukata Edward Abraham Ikuro Maruyama Masaki Kitajima Akitoshi Ishizaka | 2006 | World Journal of Surgery2006，，9： | 1 |
| 14 | Downregulation of CPI-17 contributes to dysfunctional motility in chronic intestinal inflammation model mice and ulcerative colitis patients显示文摘 | Takashi Ohama Masatoshi Hori Masahiko Fujisawa Masaharu Kiyosue Masaki Hashimoto Yuka Ikenoue Yoshio Jinno Hiroto Miwa Takayuki Matsumoto Takahisa Murata Hiroshi Ozaki | 2008 | Journal of Gastroenterology2008，，11： | 1 |
| 15 | Involvement of epidermalgrowth factor receptor-protein tyrosine kinase transactivation in endo-thelin-1-induced vascular contraction显示文摘 | Kawanabe Y Masaki T Hashimoto N | 2004 | Neurosurgery2004，100，6： | 1 |
| 16 | Endothelial-Mesenchymal Transition in Bleomycin-Induced Pulmonary Fibrosis显示文摘 | Hashimoto Naozumi Phan Sem H Imaizumi Kazuyoshi Matsuo Masaki Nakashima Harunori Kawabe Tsutomu Shimokata Kaoru Hasegawa Yoshinori | 2010 | American Journal of Respiratory Cell and Molecular Biology2010，，2： | 1 |
| 17 | A specific gene-expression signature quantifies the degree of hepatic fibrosis in patients with chronic liver disease显示文摘AIM: To study a more accurate quantification of hepatic fibrosis which would provide clinically useful information for monitoring the progression of chronic liver disease. METHODS: Using a cDNA microarray containing over 22 000 clones, we analyzed the gene-expression profiles of non-cancerous liver in 74 patients who underwent hepatic resection. We calculated the ratio of azan- stained: total area, and determined the morphologic fibrosis index (MFI), as a mean of 9 section-images. We used the MFI as a reference standard to evaluate our method for assessing liver fibrosis. RESULTS: We identified 39 genes that collectively showed a good correlation (r > 0.50) between gene-expression and the severity of liver fibrosis. Many of the identified genes were involved in immune responses and cell signaling. To quantify the extent of liver fibrosis, we developed a new genetic fibrosis index (GFI) based on gene-expression profiling of 4 clones using a linear support vector regression analysis. This technique, based on a supervised learning analysis, correctly quantified the various degrees of fibrosis in both 74 training samples (r = 0.76, 2.2% vs 2.8%, P < 0.0001) and 12 independent additional test samples (r = 0.75, 9.8% vs 8.6%, P < 0.005). It was far better in assessing liver fibrosis than blood markers such as prothrombin time (r = -0.53), type Ⅳ collagen 7s (r = 0.48), hyaluronic acid (r = 0.41), and aspartate aminotransferase to platelets ratio index (APRI) (r = 0.38). CONCLUSION: Our cDNA microarray-based strategy may help clinicians to precisely and objectively monitor the severity of liver fibrosis. | Tohru Utsunomiya Masahiro Okamoto Shigeki Wakiyama Masaji Hashimoto Kengo Fukuzawa Takahiro Ezaki Shinichi Aishima Yasuji Yoshikawa Taizo Hanai Hiroshi Inoue Graham F Barnard Masaki Mori | 2007 | World Journal of Gastroenterology2007，13，3： | 1 |
| 18 | Involvement of epidermal growth factor receptor - protein tyrosine kinase transactivation in endothelin - 1 - induced vascular con- traction显示文摘 | Kawanabe Y Masaki T Hashimoto N | 2004 | J Neurosurg2004，100，6： | 1 |
| 19 | Recommended initial loading dose of teicoplanin, established by therapeutic drug monitoring, and outcome in terms of optimal trough level显示文摘 | Masaki Sato Kingo Chida Takafumi Suda Hideaki Muramatsu Yoshinari Suzuki Hisakuni Hashimoto Hitoshi Gemma Hirotoshi Nakamura | 2006 | Journal of Infection and Chemotherapy2006，，： | 1 |
| 20 | Hydrogen production by the partial oxidation and steamreforming of tar from hot coke oven gas 显示文摘 | Masaki Onozaki Koji Watanabe Takao Hashimoto | 2006 | Fuel2006，，85： | 1 |
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