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| 1 | MicroRNAs and immunity in periodontal health and disease显示文摘MicroRNAs(miRNAs) are critical regulators of the host immune and inflammatory response against bacterial pathogens. In the present review, we discuss target genes, target gene functions, the potential regulatory role of miRNAs in periodontal tissues, and the potential role of miRNAs as biomarkers and therapeutics. In periodontal disease, miRNAs exert control over all aspects of innate and adaptive immunity, including the functions of neutrophils, macrophages, dendritic cells and T and B cells. Previous human studies have highlighted some key miRNAs that are dysregulated in periodontitis patients. In the present study, we mapped the major miRNAs that were altered in our reproducible periodontitis mouse model relative to control animals. The miRNAs that were upregulated as a result of periodontal disease in both human and mouse studies included miR-15 a, miR-29 b, miR-125 a, miR-146 a,miR-148/148 a and miR-223, whereas miR-92 was downregulated. The association of individual miRNAs with unique aspects of periodontal disease and their stability in gingival crevicular fluid underscores their potential as markers for periodontal disease progression or healthy restitution. Moreover, miRNA therapeutics hold great promise for the future of periodontal therapy because of their ability to modulate the immune response to infection when applied in conjunction with synthetic antagomirs and/or relatively straightforward delivery strategies. | Xianghong Luan Xiaofeng Zhou Afsar Naqvi Marybeth Francis Deborah Foyle Salvador Nares Thomas G.H.Diekwisch | 2018 | International Journal of Oral Science2018，10，3： | 10 |
| 2 | 高效义齿清洁剂去除菌斑染色的体外实验研究显示文摘目的:以食物色素染色模型为基础,对一种新型浸泡式义齿清洁剂去除染色的效果进行量化评估。方法:为了便于形成均一的菌斑生长表面及后期的染色测量,本研究采用聚甲基丙烯酸甲酯树脂片片来模拟义齿表面。树脂片经过消毒灭菌后浸泡于ToddHewitt肉汤培养基和人工唾液中培养18h(37℃)。处理后的树脂片取出晾干后被分为实验组和对照组,均置于咖啡、茶、蓝莓酱和红酒混合液中染色18h。使用分光光谱仪(PR650)定量测量染色前树脂片的颜色。染色后的实验组和对照组树脂片分别用义齿清洁泡腾片(Polident)和蒸馏水中浸泡5min(150mL水,40℃)。最后再次使用PR650测量树脂片颜色参数,并计算试样间色差。结果:配对t检验显示实验组和对照组的L*,a*,b*3个颜色参数以及总色差ΔE之间存在显著性差异(P<0.001)。义齿清洁泡腾片(Polident)显著地清除了色素。结论:义齿泡腾片(Polident)能清除由红酒、茶等色素引起的义齿表面着色。 | 马霄 王贻宁 Charles Dullea Marybeth Finnegan 田敏 Prasad S. Adusumilli 郭宏 Yu Shao | 2010 | 口腔医学研究2010，26，4： | 5 |
| 3 | 美国新型货车转向架显示文摘介绍了美国为改善轨道应力状况而研制的几种新型重载、高速货车转向架。 | Marybeth Luczak 宋永志 | 2005 | 国外铁道车辆2005，42，3： | 4 |
| 4 | Impaired motor control after sport-related concussion could increase risk for musculoskeletal injury:Implications for clinical management and rehabilitation显示文摘This review presents a conceptual framework and supporting evidence that links impaired motor control after sport-related concussion(SRC)to increased risk for musculoskeletal injury.Multiple studies have found that athletes who are post-SRC have higher risk for musculoskeletal injury compared to their counterparts.A small body of research suggests that impairments in motor control are associated with musculoskeletal injury risk.Motor control involves the perception and processing of sensory information and subsequent coordination of motor output within the central nervous system to perform a motor task.Motor control is inclusive of motor planning and motor learning.If sensory information is not accurately perceived or there is interference with sensory information processing and cognition,motor function will be altered,and an athlete may become vulnerable to injury during sport participation.Athletes with SRC show neuroanatomic and neurophysiological changes relevant to motor control even after meeting return to sport criteria,including a normal neurological examination,resolution of symptoms,and return to baseline function on traditional concussion testing.In conjunction,altered motor function is demonstrated after SRC in muscle activation and force production,movement patterns,balance/postural stability,and motor task performance,especially performance of a motor task paired with a cognitive task(i.e.,dual-task condition).The clinical implications of this conceptual framework include a need to intentionally address motor control impairments after SRC to mitigate musculoskeletal injury risk and to monitor motor control as the athlete progresses through the return to sport continuum. | Terese L.Chmielewski Justin Tatman Shuhei Suzuki MaryBeth Horodyski Darcy S.Reisman Russell M.Bauer James R.Clugston Daniel C.Herman | 2021 | Journal of Sport and Health Science2021，10，2： | 2 |
| 5 | Effect of the obese gene product on body weight regulation in ob/ob mice显示文摘 | Mary A P Mary J C Marybeth B | 1995 | Science1995，269，： | 1 |
| 6 | Pharmacokinetics of pantoprazole in patients with moderate and severe hepatic dysfunction显示文摘 | Geraldine M. Ferron Richard A. Preston Robert J. Noveck Paul Pockros Philip Mayer John Getsy Marybeth Turner Madelyn Abell Jeffrey Paul | 2001 | Clinical Therapeutics2001，，8： | 1 |
| 7 | Rice bran stabilization and rice bran oil extraction using ohmic heating显示文摘 | N Rao Lakkakula Marybeth Lima Terry Walker | 2004 | Bioresource Technology2004，92，4： | 1 |
| 8 | Rice bran stabilization and rice bran oil extraction using ohmic heating显示文摘 | N Rao Lakkakula Marybeth Lima Terry Walker | 2004 | Bioresource Technology2004，92，4： | 1 |
| 9 | Are small-scale landscape features important factors for field studies of small mammal dispersal sinks?显示文摘 | Marybeth Buechner | 1989 | Landscape Ecology1989，，3： | 1 |
| 10 | How Patients View Probiotics: Findings From a Multicenter Study of Patients With Inflammatory Bowel Disease and Irritable Bowel Syndrome显示文摘 | MaryBeth Mercer Margaret A. Brinich Gail Geller Krista Harrison Janelle Highland Katherine James Patricia Marshall Jennifer B. McCormick Jon Tilburt Jean-Paul Achkar Ruth M. Farrell Richard R. Sharp | 2012 | Journal of Clinical Gastroenterology2012，，2： | 1 |
| 11 | Due Process Requirements for Emergency Civil Commitments: Safeguarding Patients'Liberty Without Jeopardizing Health and Safety 显示文摘 | Marybeth Walsh | 1999 | Boston College Law Review1999，，48： | 1 |
| 12 | Cell wall integrity is dependent on the PKC1 signal transduction pathway in Cryptococcus neoformans显示文摘 | Kimberly J.Gerik Maureen J.Donlin Carlos E.Soto Annette M.Banks Isaac R.Banks Marybeth A.Maligie Claude P.Selitrennikoff Jennifer K.Lodge | 2005 | Molecular Microbiology2005，，： | 1 |
| 13 | “Functional Pain,” Functional Outcomes, and Quality of Life After Hyaluronic Acid Intra-articular Injection for Knee Osteoarthritis显示文摘 | Heather K. Vincent Cindy Montero Bryan P. Conrad MaryBeth Horodyski Jacob Connelly Matthew Martenson Amanda N. Seay Kevin R. Vincent | 2013 | PM&R2013，，4： | 1 |
| 14 | Prevention of HIV-1infection with early antiretroviral therapy显示文摘 | Myron SC Ying QC Marybeth M | 2011 | N Engl J Med2011，365，： | 1 |
| 15 | High-tech training tools显示文摘 | Marybeth Luczak | 2000 | Railway Age2000，，7： | 1 |
| 16 | The Case for Learning Communities显示文摘 | Maria Hesse & Marybeth Mason | 2005 | Community College Journal2005，，01： | 1 |
| 17 | Emergency nurses’ knowledge of pain management principles显示文摘 | Paula Tanabe MaryBeth Buschmann | 2000 | Journal of Emergency Nursing2000，，4： | 1 |
| 18 | The effect of frequency and wave form on the electrical conductivitytemperature profiles of turnip tissue显示文摘 | Lima Marybeth Heskitt B F Sastry S K | 1999 | Journal of Food Process Engineering1999，22，： | 1 |
| 19 | Brown change in fiber size,not number,in ageing skeletal muscle 显示文摘 | Marybeth | 1987 | Age and Ageing1987，，16： | 1 |
| 20 | Increasing the use of secondary fiber:an overview of deinking chemistry and stickles control 显示文摘 | Olson C R Marybeth K L | 1992 | Appita J1992，45，2： | 1 |
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