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| 1 | 皮质下小血管病诊断的共识声明显示文摘血管性认知损害是用于描述一组涉及大血管和小血管的散发性和遗传性异质性疾病的诊断术语。皮质下小血管病可导致腔隙性梗死和进行性白质损害。被称为宾斯旺格病(Binswanger's disease, BD)的进行性白质损害患者构成了从单纯血管性疾病到合并神经变性病变的疾病谱。BD患者是一个相对同质性的亚组,存在缺氧缺血、腔隙性梗死和炎症,它们协同作用破坏血脑屏障和髓鞘。通过临床、脑脊液、神经心理学和影像学检查获得的多模式疾病标记物能促进该亚组患者的鉴别。本共识声明确定了一系列基于基础病理学改变的潜在生物学标记物,这将有助于诊断以及将来协作性治疗试验的患者选择。 | Gary A Rosenberg Anders Wallin Joanna M Wardlaw Hugh S Markus Joan Montaner Leslie Wolfson Costantino Iadecola Berislav V Zlokovic Anne Joutel Martin Dichgans Marco Duering Reinhold Schmidt Amos D Korczyn Lea T Grinberg Helena C Chui Vladimir Hachinski 王训师 张劼 陈涵丰 俞娅美 徐子奇 罗本燕 | 2016 | 国际脑血管病杂志2016，24，6： | 18 |
| 2 | Sporadic versus hereditary gastrinomas of the duodenum and pancreas: Distinct clinico-pathological and epidemiological features显示文摘Gastrinomas are defined as gastrin secreting tumors that are associated with Zollinger-Ellison syndrome (ZES). ZES is characterized by elevated fasting gastrin serum levels, positive secretin stimulation test and clinical symptoms such as recurrent peptic ulcer disease, gastroesophageal re?ux disease and occasional diarrhea. Genetically, nonhereditary (sporadic) gastrinomas are distinguished from hereditary gastrinomas, which are associated with multiple endocrine neoplasia type 1 (MEN1) syndrome. In general, duodenal gastrinomas are small and solitary if they are sporadic and multiple as well as hereditary. The sporadic gastrinomas occur in the duodenum or in the pancreas while the hereditary gastrinomas almost all occur in the duodenum. Our series of 77 sporadic duodenal neuroendocrine tumors (NETs) includes 18 patients (23.4%) with gastrinomas and ZES. Of 535 sporadic NETs in the pancreas collected from the NET archives of the departments of pathology in Zürich, Switzerland, and Kiel, Germany, 24 patients (4.5%) suffered from sporadic pancreatic gastrinomas and ZES. These NETs have to be distinguished fromtumors with immunohistochemical positivity for gastrin but without evidence of ZES. An additional 19 patients suffered from MEN1 and ZES. These patients showed exclusively duodenal gastrinomas, but not pancreatic gastrinomas. The prognosis of sporadic and MEN1- associated duodenal gastrinomas is better than that of pancreatic gastrinomas, since they progress slowly to liver metastasis. In summary, sporadic and MEN1- associated gastrinomas in the duodenum and pancreas show different clinico-pathological and genetic features. The incidence of sporadic duodenal gastrin-producing tumors is increasing, possibly due to optimized diagnostic procedures. In contrast, pancreatic MEN1- associated gastrinomas seem to be extremely rare. A considerable subset of tumors with immunohistochemical expression of gastrin but without evidence of ZES should be designated as functionally inactive NETs expressing gastrin, but not as gastrinomas. | Martin Anlauf Nele Garbrecht Tobias Henopp Anja Schmitt Regina Schlenger Andreas Raffel Markus Krausch Oliver Gimm Claus F Eisenberger Wolfram T Knoefel Henning Dralle Paul Komminoth Philipp U Heitz Aurel Perren Günter Klppel | 2006 | World Journal of Gastroenterology2006，12，34： | 7 |
| 3 | Catheter-based renal sympathetic denervation for resistant hypertension: a multicentre safety and proof-of-principle cohort study显示文摘 | Henry Krum Markus Schlaich Rob Whitbourn Paul A Sobotka Jerzy Sadowski Krzysztof Bartus Boguslaw Kapelak Anthony Walton Horst Sievert Suku Thambar William T Abraham Murray Esler | 2009 | The Lancet2009，，9671： | 2 |
| 4 | Catheter-based renal sympathetic denervation for resistant hypertension: a multicentre safety and proof-of-principle cohort study显示文摘 | Henry Krum Markus Schlaich Rob Whitbourn Paul A Sobotka Jerzy Sadowski Krzysztof Bartus Boguslaw Kapelak Anthony Walton Horst Sievert Suku Thambar William T Abraham Murray Esler | 2009 | The Lancet . 2009 (9671)2009，，9671： | 2 |
| 5 | A feasible method for fractional snow cover mapping in boreal zone based on a reflectance model显示文摘 | SARI J Mets(a)m(a)ki SAKU T Anttila HUTTUNEN J Markus 2005 | 2005 | Remote Sensing of Environment2005，95，： | 1 |
| 6 | Struc- tural mechanics of railguns in the case of discrete sup- ports显示文摘 | LIUDAS T MARKUS S RIMANTAS K | 2009 | IEEE Transactions on Magnetic2009，45，1： | 1 |
| 7 | Hydraulic functions for sw- elling soils: pore scale considerations显示文摘 | MARKUS T DANI O | 2003 | Journal of Hydrology2003，272，1： | 1 |
| 8 | Soluble triggering receptor expressed on myeloid cells-1 is released in patients with stable chronic obstructive pulmonary disease 显示文摘 | Markus P Christian T Philipp H | 2007 | Chn Devel Immunol2007，11，55： | 1 |
| 9 | Comparison of two stent in modifying cerebral aneurysm hemodynamics 显示文摘 | Minsuok KM Dale BT Markus T | 2008 | Annals of Biomedical Engineering2008，36，： | 1 |
| 10 | Sampling of time-and frequency-domain signals in Monte Carlo simulations of photonmigration显示文摘 | MARKUS T ULF 0 BRIAN P | 1999 | Applied Optics1999，38，1： | 1 |
| 11 | UltraCision or high-frequency knife in transanal endoscopic microsurgery (TEM)? Advantages of a new procedure显示文摘 | Langer C Markus P Liersch T | | 0，，05： | 1 |
| 12 | Intrathecal treatment with anti - Nogo - A antibody improves functional reco- very in adult rats after stroke显示文摘 | TSAI Y MARKUS T M ANDREWS E M | 2007 | Exp Brain Res2007，182，2： | 1 |
| 13 | Energetics of CdSe Quantum Dots Adsorbed on TiO2显示文摘 | Markus T Z Itzhakov S Akotzer Y I | | 0，，27： | 1 |
| 14 | Chemoradiotherapy with capecitabine versus fluorouracil for locally advanced rectal cancer: a randomised, multicentre, non-inferiority, phase 3 trial显示文摘 | Ralf-Dieter Hofheinz Frederik Wenz Stefan Post Axel Matzdorff Stephan Laechelt J?rg T Hartmann Lothar Müller Hartmut Link Markus Moehler Erika Kettner Elisabeth Fritz Udo Hieber Hans Walter Lindemann Martina Grunewald Stephan Kremers Christian Constantin | 2012 | Lancet Oncology2012，，6： | 1 |
| 15 | A method to estimate subpixel-scale coastal polynyas with satellite passive microwave data 显示文摘 | Markus T Bums B A | 1995 | Journal of Geophysical Research1995，100，： | 1 |
| 16 | Recovery and brain reorganization after stroke in adult and aged rats显示文摘 | Markus T M Tsai S Y Bollnow M R | 2005 | Ann Neurol2005，58，6： | 1 |
| 17 | Differential enhancement of antidepressant penetration into the brain in mice with abcblab (mdrlab) P - glycoprotein gene disruption 显示文摘 | Manfred U Markus T Grauer FH | 2004 | Bio Psychol2004，54，： | 1 |
| 18 | Dose-dependent Regional Cerebral Blood Flow Changes during Remifentanil Infusion in Humans: A Positron Emission Tomography Study显示文摘 | Klaus J. Wagner Frode Willoch Eberhard F. Kochs Thomas Siessmeier Thomas R. T?lle Markus Schwaiger Peter Bartenstein | 2001 | Anesthesiology2001，，5： | 1 |
| 19 | Prognostic value of preoperative cardiac troponin I in patients undergoing emergency coronary artery bypass surgery with non-ST-elevation or ST-elevation acute coronary syndromes显示文摘 | MATTHIAS T PARWIS M MARKUS N | 2006 | Circulation2006，114，： | 1 |
| 20 | Fabrication of conti-nuous-relief microoptical elements by direct laser writing in photoresists显示文摘 | Michael T Gale Markus Rossi | 1994 | Optical Engineering1994，33，11： | 1 |
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