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| 1 | Atypical Antipsychotics in the Treatment of Depressive and Psychotic Symptoms in Patients with Chronic Schizophrenia: A Naturalistic Study显示文摘 | Marco Innamorati Stefano Baratta Cristina Di Vittorio David Lester Paolo Girardi Maurizio Pompili Mario Amore Robin Emsley | 2013 | Schizophrenia Research and Treatment2013，，： | 1 |
| 2 | Impact of living with bipolar patients: Making sense of caregivers' burden显示文摘The aim of the present review was to examine objective and subjective burdens in primary caregivers(usually family members) of patients with bipolar disorder(BD) and to list which symptoms of the patients are considered more burdensome by the caregivers. In order to provide a critical review about caregiver's burden in patients with bipolar disorder, we performed a detailed Pub Med, Bio Med Central, ISI Web of Science, Psyc INFO, Elsevier Science Direct and Cochrane Library search to identify all papers and book chapters in English published during the period between 1963 and November 2011. The highest levels of distress were caused by the patient's behavior and the patient's role dysfunction(work, education and social relationships). Furthermore, the caregiving role compromises other social roles occupied by the caregiver, becoming part of the heavy social cost of bipolar affective disorder. There is a need to better understand caregivers' views and personal perceptions of the stresses and demands arising from caring for someone with BD in order to develop practical appropriate interventions and to improve the training of caregivers. | Maurizio Pompili Désirée Harnic Xenia Gonda Alberto Forte Giovanni Dominici Marco Innamorati Konstantinos N Fountoulakis Gianluca Serafini Leo Sher Luigi Janiri Zoltan Rihmer Mario Amore Paolo Girardi | 2014 | World Journal of Psychiatry2014，4，1： | 1 |
| 3 | White matter hyperintensities and self-reported depression in a sample of patients with chronic headache显示文摘 | Gianluca Serafini Maurizio Pompili Marco Innamorati Andrea Negro Martina Fiorillo Dorian A. Lamis Denise Erbuto Francesco Marsibilio Andrea Romano Mario Amore Lidia D’Alonzo Alessandro Bozzao Paolo Girardi Paolo Martelletti | 2012 | The Journal of Headache and Pain2012，，8： | 1 |
| 4 | Periventricular white matter hyperintensities as predictors of suicide attempts in bipolar disorders and unipolar depression显示文摘 | Maurizio Pompili Marco Innamorati J. John Mann Maria A. Oquendo David Lester Antonio Del Casale Gianluca Serafini Silvia Rigucci Andrea Romano Antonino Tamburello Giovanni Manfredi Eleonora De Pisa Stefan Ehrlich Giancarlo Giupponi Mario Amore Roberto Tat | 2008 | Progress in Neuropsychopharmacology & Biological Psychiatry2008，，6： | 1 |
| 5 | The value of local political connections in a low-corruption environment显示文摘 | Mario Daniele Amore Morten Bennedsen | 2012 | Journal of Financial Economics2012，，： | 1 |
| 6 | Microstructural brain abnormalities,affective temperaments,and suicidal behavior in patients with major depression显示文摘According to magnetic resonance imaging(MRI)studies,brain white matter(WM)abnormalities have been suggested to play a critical role in the pathogenesis of major depressive disorder(MDD)and related suicidal behavior.However,MRI findings may be limited by low spatial resolution;therefore,an important contribution to the understanding of the role and significance of WM alterations derived by the development of the most recent magnetic resonance techniques,such as diffusion tensor imaging(DTI).Several DTI studies reported an association between altered WM integrity and MDD/suicidal behavior.Microstructural WM abnormalities may be located in neural circuits critically implicated in emotional processes and mood regulation resulting in enhanced vulnerability to psychiatric morbidity.WM abnormalities detected using DTI may contribute to functional deficits and help to clarify the pathophysiological mechanisms underlying MDD as well as suicidal behavior.By a clinical point of view,research also suggested that affective temperaments may play a relevant role in the psychopathological characteristics of mood disorders,clinical trajectory of episodes and polarity,long‑term outcome and suicidality.Unfortunately,only few studies investigated the association between affective temperaments and WM abnormalities and discussed their possible implications in patients with MDD and suicidal behavior.Using a comprehensive search of Medline database,the aim of the present study was to critically review the current literature on the association between WM alterations as assessed by MRI and DTI techniques,affective temperaments,MDD and suicidal behavior. | Gianluca Serafini Mario Amore Zoltan Rihmer | 2015 | Neuroimmunology and Neuroinflammation2015，2，1： | 1 |
| 7 | Associations among depression, suicidal behavior, and quality of life in patients with human immunodeficiency virus显示文摘AIM: To investigate the potential associations among major depression, quality of life, and suicidal behavior in human immunodeficiency virus(HIV) patients. METHODS: A detailed MEDLINE search was carried out to identify all articles and book chapters in English published from January 1995 to January 2015. RESULTS: Based on the main findings, the prevalence of major depressive disorder(MDD) ranged from 14.0% to 27.2%. Furthermore, the prevalence of suicidal ideation varied from 13.6% to 31.0% whereas, attempted suicides were reported to range from 3.9% to 32.7%. Interestingly, various associated risk factors for both depression and suicide were identified in HIV patients. Finally, consistent associations were reported among MDD, suicidal ideation, and poor quality of life in individuals living with HIV. CONCLUSION: Although additional studies are needed to elucidate this complex association, our results suggest the importance of early detection of both MDD and suicidality in patients living with HIV. | Gianluca Serafini Franco Montebovi Dorian A Lamis Denise Erbuto Paolo Girardi Mario Amore Maurizio Pompili | 2015 | World Journal of Virology2015，4，3： | 0 |
| 8 | White matter abnormalities:Insights into the pathophysiology of major affective disorders显示文摘The presence of white matter hyperintensities(WMHs) has been commonly associated with poor outcome in subjects with major affective disorders. Unfortunately, WMHs may be frequently confounded by the use of psychoactive medications and duration of illness. Al-though findings from the current literature are quite conflicting, we proposed that subjects with WMHs may be at higher suicidal risk when compared to other sub-groups without. Based on the Fazekas modified scale, the severity of WMHs may serve as a trait marker of disease. Interestingly, the presence of WMHs may rep-resent a neurobiological marker between the underlying vulnerability and clinical presentation of major affective disorders. | Gianluca Serafini Xenia Gonda Zoltan Rihmer Paolo Girardi Mario Amore | 2014 | World Journal of Radiology2014，6，6： | 0 |
| 9 | Factors associated with hopelessness in epileptic patients显示文摘AIM: To investigate factors related to hopelessness in a sample of epileptic patients, including measures of depression and quality of life(QOL). METHODS: Sixty-nine participants were administered the following psychometric instruments: Beck Depression Inventory-Ⅱ, Beck Hopelessness Scale(BHS), and QOLin Epilepsy(QOLIE)-89. Patients were dichotomized into two categories: those affected by epilepsy with generalized tonic-clonic seizures vs those having epilepsy with partial seizures. RESULTS: The groups differed on the QOLIE Role Limitation/Emotional dimension. Patients with generalized seizures reported more limitations in common social/role activities related to emotional problems than patients with other types of epilepsy(89.57 ± 25.49 vs 72.86 ± 36.38; t 63 =-2.16; P < 0.05). All of the respondents reported moderate to severe depression, and 21.7% of patients with generalized seizures and 28.6% of patients with other diagnoses had BHS total scores ≥ 9 indicating a higher suicidal risk. The study did not control for years of the illness. CONCLUSION: Patients with generalized seizures reported more limitations in common social/role activities related to emotional problems compared to patients with other types of seizures. Patients at increased suicide risk as evaluated by the BHS were older than those who had a lower suicidal risk. Future studies are required to further investigate the impact of hopelessness on the outcome of epileptic patients. | Maurizio Pompili Gianluca Serafini Marco Innamorati Franco Montebovi Dorian A Lamis Mariantonietta Milelli Manuela Giuliani Matteo Caporro Paolo Tisei David Lester Mario Amore Paolo Girardi Carla Buttinelli | 2014 | World Journal of Psychiatry2014，4，4： | 0 |
| 10 | The role of glutamate excitotoxicity and neuroinflammation in depression and suicidal behavior:focus on microglia cells显示文摘Major depressive disorder(MDD)is associated with a significant disability worldwide,relevant psychosocial impairment,and increased risk of suicidal behavior.[1]Although multiple psychoactive compounds are now available,[2]more than 20%of MDD patients treated with traditional antidepressant drugs do not benefit from complete recovery and are affected by treatment-resistance.[3]Traditional antidepressant medications may be ineffective and sometimes worsen depressive symptoms in a vulnerable subpopulation of patients with subthreshold hypomanic symptoms that may be better included in the bipolar spectrum rather than MDD.[4] | Gianluca Serafini Zoltan Rihmer Mario Amore | 2015 | Neuroimmunology and Neuroinflammation2015，2，1： | 0 |
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