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| 1 | Impact of body composition on survival and morbidity after liver resection in hepatocellular carcinoma patients显示文摘Background: Hepatocellular carcinoma is the most common innate liver tumor. Due to improved surgical techniques, even extended resections are feasible, and more patients can be treated with curative intent. As the liver is the central metabolic organ, preoperative metabolic assessment is crucial for risk stratification. Sarcopenia, obesity and sarcopenic obesity characterize body composition and metabolic status. Here we present the impact of body composition on survival after liver resection in patients with hepatocellular carcinoma. Methods: A retrospective database analysis of 70 patients who were assigned for liver resection due to hepatocellular carcinoma was conducted. For assessment of sarcopenia and obesity, skeletal muscle surface area was measured at lumbar vertebra 3 level(L3) in preoperative four-phase contrast enhanced abdominal CT scans, and L3 muscle index and body fat percentage were calculated. Results: Univariate analysis comparing the survival curves using the score test demonstrated superior postoperative overall survival for sarcopenic( P = 0.035) and sarcopenic obese( P = 0.048) patients as well as a trend favoring obese( P = 0.130) subjects. Whereas multivariate analysis could not identify significant difference in postoperative survival regarding sarcopenia, obesity or sarcopenic obesity. Only large tumor size, multifocal disease and male gender were risk factors for long-term survival. Conclusions: Sarcopenia, obesity and sarcopenic obesity are indeed no risk factors for poor postoperative survival in this study. Our data do not support the evaluation of sarcopenia, obesity and sarcopenic obesity before liver resection in hepatocellular carcinoma patients. | Andreas Kroh Diane Uschner Toine Lodewick Roman M Eickhoff Wenzel Sch?ning Florian T Ulmer Ulf P Neumann Marcel Binneb?sel | 2019 | Hepatobiliary & Pancreatic Diseases International2019，18，1： | 5 |
| 2 | Fractional Flow Reserve Versus Angiography for Guiding Percutaneous Coronary Intervention in Patients With Multivessel Coronary Artery Disease显示文摘 | Nico H.J. Pijls William F. Fearon Pim A.L. Tonino Uwe Siebert Fumiaki Ikeno Bernhard Bornschein Marcel van't Veer Volker Klauss Ganesh Manoharan Thomas Engstr?m Keith G. Oldroyd Peter N. Ver Lee Philip A. MacCarthy Bernard De Bruyne | 2010 | Journal of the American College of Cardiology2010，，3： | 2 |
| 3 | Biotransformation of S-Triaxine herbicides and related degradation products in liquid cultures by the white rot fungus Phanerochaete chrysosporium显示文摘 | CHRISTIAN M CHANTAL L MARCEL A T | 1997 | Pestie Sci1997，49，： | 1 |
| 4 | Effect of the factor V Leiden mutation on the incidence and outcome of severe infection and sepsis 显示文摘 | Marcel Schouten C Van't Veer T Van Der Poll | 2012 | Neth J Med2012，70，7： | 1 |
| 5 | Mechanical and morphological variation of the human lumbar vertebral cortical and tra becular bone显示文摘 | Marcel E R Rho Jae-Young Ting Y T | 1999 | J Biomed Mater Res1999，44，： | 1 |
| 6 | Watersnakes: energy driven watershed segmentation 显示文摘 | HIEU T MARCEL M REIN V | 2003 | IEEE Transaction on Pattern Analy- sis and Machine Intelligence2003，25，3： | 1 |
| 7 | Elastic properties of microstructural components of human bone tissue as measured by nanoindentation显示文摘 | Rho Jae-Young Marcel E R Ting Y T | 1999 | J Biomed Mater Res1999，45，： | 1 |
| 8 | Watersnakes: Energy-driven watershed segmentation 显示文摘 | HIEU T MARCEL M REIN V | 2003 | IEEE Transaction on Pattern Analysis and Machine Intelligence2003，25，3： | 1 |
| 9 | Oil-cracking processes evidence from synthetic petroleum inclusions显示文摘 | Stephane T Marcel E Jacques P | 2003 | Journal of Geochemical Exploration2003，26，7879： | 1 |
| 10 | Angiographic Versus Functional Severity of Coronary Artery Stenoses in the FAME Study显示文摘 | Pim A.L. Tonino William F. Fearon Bernard De Bruyne Keith G. Oldroyd Massoud A. Leesar Peter N. Ver Lee Philip A. MacCarthy Marcel van’t Veer Nico H.J. Pijls | 2010 | Journal of the American College of Cardiology2010，，25： | 1 |
| 11 | Artifacts of Mark- ov blanket filtering based on discretized features in small sample size applications 显示文摘 | Theo A K Marcel J T R Lodewyk F A W | 2006 | Pattern Recognition Letters2006，27，7： | 1 |
| 12 | Watersnakes:energy-driven watershed segmentation显示文摘 | HIEU T MARCEL M REIN V | 2003 | IEEE Trans on Pattern Analysis and Machine Intelligence2003，25，3： | 1 |
| 13 | Efficacy and side effects of praziquantel against Schistosoma mansoni in a community of western C?te d’Ivoire显示文摘 | Giovanna Raso Eliézer K N'Goran Abale Toty Anne Luginbühl Cynthia A Adjoua Norbert T Tian-Bi Isaac I Bogoch Penelope Vounatsou Marcel Tanner Jürg Utzinger | 2003 | Transactions of the Royal Society of Tropical Medicine and Hygiene2003，，1： | 1 |
| 14 | Spatially-resolved EELS analysis of antibody distribution on biofunctionalized magnetic nanoparticles显示文摘 | Raul A Laura D M Laura C Alvaro M Marcel T Valeria G Jesus M D L F Clara M Ricardo 1 | 2013 | ACS Nano2013，7，5： | 1 |
| 15 | High diversity of genes for nonhost resistance of barley to heterologous rust fungi显示文摘 | Jafary H Albertazzi G Marcel T C | 2008 | Genetics2008，178，： | 1 |
| 16 | The Role of Ketamine in Preventing Fentanyl-Induced Hyperalgesia and Subsequent Acute Morphine Tolerance显示文摘 | Jean-Paul Laulin Pierre Maurette Jean-Beno?t Corcuff Cyril Rivat Marcel Chauvin and Guy Simonnet | 2002 | Anesthesia & Analgesia2002，，5： | 1 |
| 17 | Continuous small dose aprotinin controls fibrinolylsys during orthotopic liver transplantation显示文摘 | Marcel R J Stegall W C Suit C T | 1996 | Anesth-Analg1996，82，6： | 1 |
| 18 | Percutaneous Coronary Intervention of Functionally Nonsignificant Stenosis显示文摘 | Nico H.J. Pijls Pepijn van Schaardenburgh Ganesh Manoharan Eric Boersma Jan-Willem Bech Marcel van't Veer Frits B?r Jan Hoorntje Jacques Koolen William Wijns Bernard de Bruyne | 2007 | Journal of the American College of Cardiology2007，，21： | 1 |
| 19 | Safety of once-daily insulin detemir in patients with type 2 diabetes treated with oral hypoglycemic agents in routine clinical practice显示文摘 | Stuart Ross Grzegorz Dzida Qiuhe Ji Marcel Kaiser Rober t Ligthelm Luigi Meneghini Avideh Nazeri Domingo Oroz co-Beltran Changyu Pan Anne Louise Svendsen | 2014 | Journal of diabetes2014，6，3： | 1 |
| 20 | A multifunctional prokaryotic protein expression system:Overproduction,affinity purification and selestive detection显示文摘 | KROLL D J ABDEL-HAFIZ H MARCELL T | 1993 | DNA Cell Biol1993，12，5： | 1 |
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