5篇
您的检索式：作者名="Manmohan Parida"
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| 1 | Cloning and expression of domain III of the envelope gene of Japanese encephalitis virus: Evaluation for early clinical diagnosis by IgM ELISA显示文摘 | Jyoti Shukla Rakesh Bhargava Paban Kumar Dash Manmohan Parida Nagesh Tripathi P.V. Lakshmana Rao | 2009 | Journal of Virological Methods2009，，1： | 1 |
| 2 | Assessment of immunogenic potential of Vero adapted formalin inactivated vaccine derived from novel ECSA genotype of Chikungunya virus显示文摘 | Mugdha Tiwari Manmohan Parida S.R. Santhosh Mohsin Khan Paban Kumar Dash P.V. Lakshmana Rao | 2009 | Vaccine2009，，18： | 1 |
| 3 | Rapid detection and differentiation of dengue virus serotypes by a real-time reverse transcription-loop-mediated isothermal amplification assay显示文摘 | Manmohan Parida Kouhei Horioke Hiroyuki Ishida | 2005 | Journal of Clinical Microbiology2005，43，6： | 1 |
| 4 | Andrographolide inhibits chikungunya virus infection by up-regulating host innate immune pathways显示文摘Objective: To investigate the therapeutic efficacy of andrographolide, a plant derived compound, against chikungunya virus(CHIKV) infection. Methods: Using flow cytometry and immunoblotting assay, in vitro viral protein expression was studied in THP-1 cells line. In Balb/c mouse neonates, viral RNA copy number was determined by real time PCR. Results:The results showed reduced CHIKV protein expression on andrographolide treatment in CHIKV-infected human peripheral blood mononuclear cells, Vero cells and THP-I cell line.In vivo, andrographolide treatment to CHIKV-infected neonates reduced viral RNA copy number. Further. andrographolide also increased cytotoxic T lymphocytes both in vitro and in vivo. Andrographolide also activated host innate immune pathways, viz., protein kinase R.phosphorylated eukaryotic initiation factor 2 α, retinoic acid inducible gene-Ⅰ and interferon regulatory factor 3/7, thereby increasing IFN-a secretion. CHIKV-induced nuclear factor κlight chain enhancer of activated B cells and tumor necrosis factor-a was also reduced on andrographolide treatment. Conclusion: Andrographolide inhibits CHIKV by suppressing viral protein expression and up-regulating host innate immunity and hence could be an effective therapeutic agent against CHIKV infection. | Swati Gupta Kamla Prasad Mishra Paban Kumar Dash Manmohan Parida Lilly Ganju Shashi Bala Singh | 2018 | Asian Pacific Journal of Tropical Medicine2018，11，3： | 1 |
| 5 | Real- time reverse transcription loop-mediated isothermal amplification for rapid detection of West Nile Virus 显示文摘 | Manmohan Parida Guillermo Posadas Shingo Inoue | 2004 | J Clin Microbiol2004，42，1： | 1 |
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