|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Relative pollen productivities of typical steppe species in northern China and their potential in past vegetation reconstruction显示文摘The Relative Pollen Productivities(RPPs)of common steppe species are estimated using Extended R-value(ERV)model based on pollen analysis and vegetation survey of 30 surface soil samples from typical steppe area of northern China.Artemisia,Chenopodiaceae,Poaceae,Cyperaceae,and Asteraceae are the dominant pollen types in pollen assemblages,reflecting the typical steppe communities well.The five dominant pollen types and six common types(Thalictrum,Iridaceae,Potentilla,Ephedra,Brassicaceae,and Ulmus)have strong wind transport abilities;the estimated Relevant Source Area of Pollen(RSAP)is ca.1000 m when the sediment basin radius is set at 0.5 m.Ulmus,Artemisia,Brassicaceae,Chenopodiaceae,and Thalictrum have relative high RPPs;Poaceae,Cyperaceae,Potentilla,and Ephedra pollen have moderate RPPs;Asteraceae and Iridaceae have low RPPs.The reliability test of RPPs revealed that most of the RPPs are reliable in past vegetation reconstruction.However,the RPPs of Asteraceae and Iridaceae are obviously underestimated,and those of Poaceae,Chenopodiaceae,and Ephedra are either slightly underestimated or slightly overestimated,suggesting that those RPPs should be considered with caution.These RPPs were applied to estimating plant abundances for two fossil pollen spectra(from the Lake Bayanchagan and Lake Haoluku)covering the Holocene in typical steppe area,using the'Regional Estimates of Vegetation Abundance from Large Sites'(REVEALS)model.The RPPs-based vegetation reconstruction revealed that meadow-steppe dominated by Poaceae,Cyperaceae,and Artemisia plants flourished in this area before 6500–5600 cal yr BP,and then was replaced by present typical steppe. | XU QingHai CAO XianYong TIAN Fang ZHANG ShengRui LI YueCong LI ManYue LI Jie LIU YaoLiang LIANG Jian | 2014 | Science China Earth Sciences2014，57，6： | 13 |
| 2 | Surface pollen assemblages of human-disturbed vegetation and their relationship with vegetation and climate in Northeast China显示文摘Pollen assemblages of 53 surface pollen samples from farmlands and wastelands in Northeast China were analyzed. Tree pollen percentages were usually higher than 30%, with Pinus (26.9%), Quercus (0.9%), Betula (0.9%) and Populus (0.7%) as the major types, and herb pollen percentages were usually higher than 50%, with weedy Poaceae (8.7%), Chenopodiaceae (7.1%), Artemisia (1.9%) and Compositae (3.5%) as the major taxa. Thus, the pollen assemblages were consistent with the regional vegetation compositions. However, there were differences in pollen assemblages among regions, especially among different geomorphological units. For example, in the mountains, there were more types of tree pollen and higher total percentages (average 42%) than in other areas, while cereal pollen percentages were lowest (11.2%). In the hills and high plains, herbs made up more than 60% of the pollens, with cereals (average 53.6%) the dominant type. In the low plains, pollen types were similar to those in the hills and high plains, but total pollen concentrations and the proportion of Concentricystes were much higher, while cereal pollen percentages were slightly lower (average 41.6%). Pollen assemblages in different land use types also differed. For example, in farmland, cereal pollen percentages were more than 40% and Chenopodiaceae was usually less than 2.5%, while in wasteland, weedy Poaceae was usually less than 10% and Chenopodiaceae was usually higher than 25%. Total pollen concentrations in farmland (average 3909 grains/g) were much lower than in wasteland (average 15074 grains/g). Redundancy analysis revealed that pollen assemblages were significantly negatively correlated with mean annual temperature (-0.73) and July mean temperature (-0.81) and significantly positively correlated with mean annual precipitation (0.48), indicating that pollen assemblages in the artificial or human-disturbed vegetation reflect regional climate well. Comparison of pollen assemblages in different areas of northern China showed that pollen concentrations reflect the intensities of human impact to some degree. For example, pollen concentrations decrease as human impacts increase in intensity. The cereal pollen proportions in farmland differed by area. In Northeast China, cereal pollen proportions were distinctly higher than in most other areas of northern China, suggesting differences in planting habits and climate. | LI ManYue LI YueCong XU QingHai PANG RuiMing DING Wei ZHANG ShengRui HE ZhiGuo | 2012 | Chinese Science Bulletin2012，57，5： | 10 |
| 3 | A Genome Sequence of Novel SARS-CoV Isolates: the Genotype, GD-Ins29, Leads to a Hypothesis of Viral Transmission in South China显示文摘We report a complete genomic sequence of rare isolates (minor genotype) of theSARS-CoV from SARS patients in Guangdong, China, where the first few casesemerged. The most striking discovery from the isolate is an extra 29-nucleotidesequence located at the nucleotide positions between 27,863 and 27,864 (referredto the complete sequence of B J01) within an overlapped region composed of BGI-PUP5 (BGI-postulated uncharacterized protein 5) and BGI-PUP6 upstream ofthe N (nucleocapsid) protein. The discovery of this minor genotype, GD-Ins29,suggests a significant genetic event and differentiates it from the previously re-ported genotype, the dominant form among all sequenced SARS-CoV isolates. A17-nt segment of this extra sequence is identical to a segment of the same size intwo human mRNA sequences that may interfere with viral genome replication andtranscription in the cytosol of the infected cells. It provides a new avenue for theexploration of the virus-host interaction in viral evolution, host pathogenesis, andvaccine development. | E‘deQin XiongleiHe WeiTian YongLiu WeiLi JieWen BingyinSi YongwuHu WenmingPeng LinTaug TaoJiang JianpingShi JiaJia YuZhang JiaYe Cui’eWang YujunHan JingqiangWang BaochangFan QingfaWu GuohuiChang WuchunCao ZuyuanXu RuifuYang JmgWang ManYu YanLi JingXu JunZhou YajumDeng XiaoyuLi JianfeiHu CaipingWang ChunxiaYan QingrunZhang JingyueBao GuoqingLi HaiqingZhang YilinZhang HuiZhao XiaoweiZhang ShuangliLi XiaoJieCheng XiuqingZhang BinLiu ChangqingZeng HuanmingYang WeijunChen LinFang ChangfengLi MengLei DaweiLi WeiTong XiangjunTian JianWang BoZhang SonggangLi XuehaiTan SiqiLiu WeiDong JunWang GaneKa-ShuWong JunYu QingyuZhu | 2003 | Genomics, Proteomics & Bioinformatics2003，1，2： | 6 |
| 4 | Behaviors of Leucine and Isoleucine in Ion Mobility- Quadrupole Time of Flight Mass Spectrometry显示文摘在这研究,离子活动性分离结合了双人脚踏车团 spectrometry (IM 双人脚踏车 MS ) 被利用包括白氨酸和异白氨酸调查二氨基酸的电离行为。在 electrospray 电离(ESI ) 下面模式,在各分子的 sturcture 的二个 protonation 地点引起了 protomer 的二种形式。一个人产生了从氨基从 carboxyl 的 protonated (amino-protomer ) 和其它正在是 protonated (carboxyl-protomer ) 。在里面二维(飘移时间, m/z ) 光谱, protomers 有一样的团,而是可区分的飘移时间和破碎模式。为描述目的, protomers 的理论碰撞十字节(CCS ) 价值被计算并且证明与一致试验性。而且,在氨基酸之间的确定的关系和他们的 protomers 被评估。它证明 carboxyl-protomer 是的许多与氨基酸的集中成正比,而 amino-protomer 的没有一样的趋势。在气压化学药品电离(APCI ) 下面模式,仅仅 carboxyl-protomer 被观察。另外, amino-protomer 和在 ESI 下面观察的簇离子完全是不在的。结果证明电离模式不仅在 therir protomers 的形式上而且在确定的关系上重重地影响白氨酸和异白氨酸的电离行为。 | Su Guo Fang Zhang Haoyang Wang Manyu Zhang Zhixu Zhang Xiang Zhang Yinlong Guo | 2015 | Chinese Journal of Chemistry2015，33，12： | 4 |
| 5 | Spatial patterns of vegetation and climate in the North China Plain during the Last Glacial Maximum and Holocene climatic optimum显示文摘Reconstructing the spatial patterns of regional climate and vegetation during specific intervals in the past is important for assessing the possible responses of the ecological environment under future global warming scenarios. In this study, we reconstructed the history of regional vegetation and climate based on six radiocarbon-dated pollen records from the North China Plain. Combining the results with existing pollen records, we reconstruct the paleoenvironment of the North China Plain during the Last Glacial Maximum(LGM) and the Holocene Climatic Optimum(HCO). The results show that changes in the regional vegetation since the LGM were primarily determined by climatic conditions, the geomorphic landscape and by human activity.During the LGM, the climate was cold and dry;mixed broadleaf-coniferous forest and deciduous-evergreen broadleaf forest developed in the southern mountains, and cold-resistant coniferous forest and mixed broadleaf-coniferous forest were present in the northern mountains. The forest cover was relatively low, with mesophytic and hygrophilous meadow occupying the southern part of the plain, and temperate grassland and desert steppe were distributed in the north;Chenopodiaceae-dominated halophytes grew on the exposed continental shelf of the Bohai Sea and Yellow Sea. During the HCO, the climate was warm and wet;deciduous broadleaf forest and deciduous-evergreen broadleaf forest, with subtropical species, developed in the southern mountains, and deciduous broadleaf forest with thermophilic species was present in northern mountains. Although the degree of forest cover was greater than during the LGM, the vegetation of the plain area was still dominated by herbs, while halophytes had migrated inland due to sea level rise. In addition, the expansion of human activities, especially the intensification of cultivation,had a significant influence on the natural vegetation. Our results provide data and a scientific basis for paleoclimate modelling and regional carbon cycle assessment in north China, with implications for predicting changes in the ecological environment under future global warming scenarios. | Manyue LI Shengrui ZHANG Qinghai XU Jule XIAO Ruilin WEN | 2019 | Science China Earth Sciences2019，62，8： | 4 |
| 6 | The crystal structure of Ac-AChBP in complex with α-conotoxin LvlA reveals the mechanism of its selectivity towards different nAChR subtypes显示文摘3* nAChRs,被认为为象疼痛那样的问题正在答应药目标,嗜好,心血管的功能,认知混乱等等,在整个中央、外部的神经系统被发现。-conotoxin (-CTx) LvIA 作为迄今为止知道的 32 nAChRs 的最选择的禁止者被识别了,并且它能把 32 nAChR 子类型与 6/323 和 34 种 nAChR 子类型区分开来。然而,它向 32 的选择的机制, 6/323,和 34 nAChRs 留下逃犯。这里,我们在 3.4 的一个决定与 Aplysia californica 醋胆素绑定蛋白质(Ac-AChBP ) 在建筑群报导 LvIA 的合作水晶结构 ? 。基于这建筑群的结构,和基于另外的 nAChR 子类型和有约束力的亲密关系试金当模特儿的相同,我们断定 LvIA 的 Asp-11 在选择起一个重要作用向 32 的 LvIA 和由做盐的 3/623 nAChRs 与老鼠的 Lys-155 衔接 3 子单元。在被老鼠的 Met-36, Thr-59,和 Phe-119 形成的一个恐水病的衣袋以内的 Asn-9 谎言在 32 nAChR 模型的 2 子单元,向 32 nAChR 子类型为它的更多的有势力选择揭示原因。这些结果提供能被用来设计 ligands 的分子的卓见有选择地指向 32 nAChRs,与为新治疗学的 -CTxs 的设计的重要含意。 | Manyu Xu Xiaopeng Zhu Jinfang Yu Jinpeng Yu Sulan Luo Xinquan Wang | 2017 | Protein & Cell2017，8，9： | 3 |
| 7 | Cytosolic phospholipase A2α modulates cell-matrix adhesion via the FAK/paxillin pathway in hepatocellular carcinoma显示文摘Objective: To explore the effect of cytosolic phospholipase A2α(cPLA2α) on hepatocellular carcinoma(HCC) cell adhesion and the underlying mechanisms.Methods: Cell adhesion, detachment, and hanging-drop assays were utilized to examine the effect of cPLA2α on the cell-matrix and cell-cell adhesion. Downstream substrates and effectors of cPLA2α were screened via a phospho-antibody microarray.Associated signaling pathways were identified by the functional annotation tool DAVID. Candidate proteins were verified using Western blot and colocalization was investigated via immunofluorescence. Western blot and immunohistochemistry were used to detect protein expression in HCC tissues. Prognosis evaluation was conducted using Kaplan-Meier and Cox-proportional hazards regression analyses.Results: Our findings showed that cPLA2α knockdown decreases cell-matrix adhesion but increases cell-cell adhesion in HepG2 cells. Microarray analysis revealed that phosphorylation of multiple proteins at specific sites were regulated by cPLA2α. These phosphorylated proteins were involved in various biological processes. In addition, our results indicated that the focal adhesion pathway was highly enriched in the cPLA2α-relevant signaling pathway. Furthermore, cPLA2α was found to elevate phosphorylation levels of FAK and paxillin, two crucial components of focal adhesion. Moreover, localization of p-FAK to focal adhesions in the plasma membrane was significantly reduced with the downregulation of cPLA2α. Clinically, cPLA2α expression was positively correlated with p-FAK levels. Additionally, high expression of both cPLA2α and p-FAK predicted the worst prognoses for HCC patients.Conclusions: Our study indicated that cPLA2α may promote cell-matrix adhesion via the FAK/paxillin pathway, which partly explains the malignant cPLA2α phenotype seen in HCC. | Piao Guo Yuchao He Lu Chen Lisha Qi Dongming Liu Ziye Chen Manyu Xiao Liwei Chen Yi Luo Ning Zhang Hua Guo | 2019 | Cancer Biology & Medicine2019，16，2： | 2 |
| 8 | Effects of Environmental Conditions and Aboveground Biomass on CO2 Budget in Phragmites australis Wetland of Jiaozhou Bay,China显示文摘Estuarial saline wetlands have been recognized as a vital role in CO_2 cycling.However,insufficient attention has been paid to estimating CO_2 fluxes from estuarial saline wetlands.In this study,the static chamber-gas chromatography(GC) method was used to quantify CO_2 budget of an estuarial saline reed(Phragmites australis) wetland in Jiaozhou Bay in Qingdao City of Shandong Province,China during the reed growing season(May to October) in 2014.The CO_2 budget study involved net ecosystem CO_2 exchange(NEE),ecosystem respiration(Reco) and gross primary production(GPP).Temporal variation in CO_2 budget and the impact of air/soil temperature,illumination intensity and aboveground biomass exerted on CO_2 budget were analyzed.Results indicated that the wetland was acting as a net sink of 1129.16 g/m^2 during the entire growing season.Moreover,the values of Reco and GPP were 1744.89 g/m^2 and 2874.05 g/m^2,respectively;the ratio of Reco and GPP was 0.61.Diurnal and monthly patterns of CO_2 budget varied significantly during the study period.Reco showed exponential relationships with air temperature and soil temperature at 5 cm,10 cm,20 cm depths,and soil temperature at 5 cm depth was the most crucial influence factor among them.Meanwhile,temperature sensitivity(Q10) of Reco was negatively correlated with soil temperature.Light and temperature exerted strong controls over NEE and GPP.Aboveground biomass over the whole growing season showed non-linear relationships with CO_2 budget,while those during the early and peak growing season showed significant linear relationships with CO_2 budget.This research provides valuable reference for CO_2 exchange in estuarial saline wetland ecosystem. | GAO Manyu KONG Fanlong XI Min LI Yue LI Jihua | 2017 | Chinese Geographical Science2017，27，4： | 2 |
| 9 | Assessment of Left and Right Ventricular Systolic and Diastolic Synchronicity in Normal Subjects by Tissue Doppler Echocardiography and the Effects of Age and Heart Rate显示文摘 | Cheuk‐ManYu HongLin Pui‐ChingHo HuaYang | 2003 | Echocardiography2003，，1： | 1 |
| 10 | A parallel algorithm based on Galerkin theory block-tridiagonal liner systems显示文摘 | Lv Quanyi Xiao Manyu Zhou Min | 2007 | Applied Mathematics and Computation2007，187，： | 1 |
| 11 | Response of daily stem radial growth of Platycladus onentahs toenvironmental factors in a semi-arid area of North China显示文摘 | JIANG Yuan WANG Bingqin DONG Manyu | 2015 | Trees2015，29，1： | 1 |
| 12 | AI-Fe-Ce Alloys Applications显示文摘 | Neikov O D Mil' manYu V Sirko A L | 2007 | Powder Metallurgy and Metal Ceramics2007，46，910： | 1 |
| 13 | A parallel iterative method for solving periodical block-tridiagonal linear equations显示文摘 | Xiao Manyu Lu Quanyi | 2007 | Applied Mathematics and Computation2007，184，： | 1 |
| 14 | A parallel algorithm based on Galerkin theory for block-tridiagonal linear systems显示文摘 | Lu Quanyi Xiao Manyu Zhou Min | 2007 | Applied Mathematics and Computation2007，187，： | 1 |
| 15 | Complete Genome Sequences of the SARS-CoV: the BJ Group (Isolates BJ01-BJ04)显示文摘Beijing has been one of the epicenters attacked most severely by the SARS-CoV (severe acute respiratory syndrome-associated coronavirus) since the first patient was diagnosed in one of the city's hospitals. We now report complete genome sequences of the BJ Group, including four isolates (Isolates B J01, B J02, B J03,and B J04) of the SARS-CoV. It is remarkable that all members of the BJ Group share a common haplotype, consisting of seven loci that differentiate the group from other isolates published to date. Among 42 substitutions uniquely identifled from the BJ group, 32 are non-synonymous changes at the amino acid level.Rooted phylogenetic trees, proposed on the basis of haplotypes and other sequence variations of SARS-CoV isolates from Canada, USA, Singapore, and China, gave rise to different paradigms but positioned the BJ Group, together with the newly discovered GD01 (GD-Ins29) in the same clade, followed by the H-U Group (from Hong Kong to USA) and the H-T Group (from Hong Kong to Toronto), leaving the SP Group (Singapore) more distant. This result appears to suggest a possible transmission path from Guangdong to Beijing/Hong Kong, then to other countries and regions. | ShengliBi E‘deQin ZuyuanXu WeiLi JingWang YongWuHu YongLiu ShuminDuan JianfeiHu YujunHan JingXu YanLi YaoYi YongdongZhou WeiLin1 JieWen HongXu RuanLi ZizhangZhang HaiyanSun JinguiZhu ManYu BaochangFan QingfaWu WeiLin2 LinTang Bao’anYang GuoqingLi WenmingPeng WenjieLi TaoJiang YajunDeng BohuaLiu JianpingShi YongqiangDeng WeiWei HongLiu ZongzhongTong FengZhang YuZhang Cui‘eWang YuquanLi JiaYe YonghuaGan JiaJi XiaoyuLi XiangjunTian FushuangLu GangTan RuifuYang BinLiu SiqiLiu SonggangLi JunWang JianWang WuchunCao JunYu XiaopingDong HuanmingYang | 2003 | Genomics, Proteomics & Bioinformatics2003，1，3： | 1 |
| 16 | Catalytic transfer hydrogenolysis of C–O bonds in lignin model compounds without arene hydrogenation显示文摘The shortage of resources and the destruction of the environment have caused serious resource and environmental problems shared by all countries around the world. As a ubiquitous renewable resource, biomass has great prospects for replacing fossil energy and attracted attention from the society. The use of catalytic approach to transform biomass into high-value chemicals is an effective way to use biomass efficiently. In this work, Nisupported catalysts has been developed for the selective cleavage of C–O bonds in lignin model compounds with 2-propanol as the hydrogen source solvent. Among these catalysts, it was indicated that zirconium phosphate(Zr P)-supported Ni catalysts were highly efficient and recyclable for alkyl-aryl ether(α-O-4 and β-O-4) cleavage in lignin model compounds. The further investigation demonstrated that the transfer hydrogenolysis of the C–O bond is highly selective, which afforded phenols and aromatics as dominant products without the products arising from hydrogenation of aromatic rings. Through a series of characterization of the catalyst, it was demonstrated that the medium strong acid sites of the Zr P support promoted the cleavage of alkyl-aryl ethers(α-O-4 and β-O-4),and Br?nsted acid sites favored for achieving high selectivity toward C–O bond cleavage. Additionally, Ni(0) sites on the Zr P catalysts were responsible for the catalytic transfer hydrogenolysis. | Kai Cui Xiuge Zhao Qingpo Peng Honghui Gong Xinjia Wei Jiajia Wang Manyu Chen Zhenshan Hou | 2022 | Green Chemical Engineering2022，3，1： | 1 |
| 17 | Numerical modelling of MOV with Voronoi network and finite element method显示文摘The electrical and thermal characteristics of metal oxide varistor(MOV)are essential for the study of MOV performance and degradation.This paper provides a modelling method of MOV to simulate its microstructure geometry with the Voronoi network and derive the electrical functions on the grain boundaries.A series of discrete data to describe the resistance-voltage(R-V)characteristics of MOV from experiments is applied to the pro-posed model.Through 8/20μs surge current experiments,the electrical conductivity of MOV is determined to achieve the simulation of the clamping voltage.With this model,the current distribution and temperature distribution over a MOV sample are simulated and analysed by the finite element method(FEM).The simulation results show good agreement with the experimental measurement and inherent feature of MOV. | Qibin Zhou Hongxiang Yang Xin Huang Manyu Wang Xin Ren | 2021 | High Voltage2021，6，4： | 1 |
| 18 | Polymermonolith microextraction online coupled to hydrophilicinteraction chromatography/mass spectrometry for a-nalysis ofβ2-agonist in human urine显示文摘 | Zheng Mingming Zhang Manyu Feng Yuqi | 2009 | J Sep Sci2009，32，11： | 1 |
| 19 | The effect of LyPRP/collagen composite hydrogel on osteogenic differentiation of rBMSCs显示文摘Although platelet-rich plasma(PRP)plays a significant role in the orthopedic clinical application,it still faces two major problems,namely,uncontrollable factors release,frequent preparation and extraction processes as well as the inconvenient form of usage.To overcome these shortcomings,freeze-dried PRP(LyPRP)was encapsulated into bioactive Col I hydrogel to induce osteogenic dif-ferentiation of rabbit bone marrow mesenchymal stem cells(rBMSCs).And PRP/Col I composite hydrogel was prepared as a control.Compared with Col I hydrogel,the introduction of platelets significantly improved the mechanical properties of hydrogels.Meanwhile,platelets were evenly distributed in the composite hydrogels network.The sustainable release of related factors in the composite hydrogels could last for more than 14days to maintain its long-term biological activity.Further cell experiments confirmed that PRP and LyPRP could effectively alleviate the contraction of collagen hydrogel in vitro,and promote the adhesion,proliferation and osteogenesis differentia-tion of rBMSCs.The results of osteogenic gene expression indicated that the 10%LyPRP/Col I composite hydrogel could facilitate the early expression of BMP-2 and late osteogenic associated protein formation with higher expression of alkaline phosphatase and Osteocalcin(OCN).These results might provide new insights for the clinical application of 10%LyPRP/Col I composite hydro-gel as practical bone repair injection. | Manyu Chen Quanying Liu Yang Xu Yuxiang Wang Xiaowen Han Zhe Wang Jie Liang Yong Sun Yujiang Fan Xingdong Zhang | 2021 | Regenerative Biomaterials2021，8，1： | 1 |
| 20 | MAPK regulates cell cycle progression in pig oocytes and fertilized eggs显示文摘Oocytes collected from prepubertal gilt ovaries were matured in vitro (IVM), and fertilized in vitro (IVF) or electrically activated. Phosphorylation of mitogen-activated protein kinase (MAPK) was detected with SDS-PAGE and Western blotting, and translocation of ERK2 was observed with immunofluorescent cytochemistry. We found that the quantity of MAPK kept unchanged during oocyte maturation. There was no phosphorylated MAPK in porcine oocytes at the germinal vesicle (GV) stage; a little MAPK was phosphorylated at 20 h of IVM; a high level phosphory-lation was detected at 30 h, while MAPK phosphorylation decreased at 36 h; and then MAPK phosphorylation increased again to the peak level from 40 to 60 h. ERK2 translocated from the peripheral cytoplasm to inner cytoplasm and nuclear area during oocyte maturation. There was nearly no phosphorylated MAPK at 18 and 20 h of electrically activated oocytes, but phosphorylation increased at 22 h. There was no phosphorylated MAPK at 12 h of IVF, while | LI Manyu FAN Hengyu TONG Chao CHEN Dayuan XIA Guoliang SUN Qingyuan | 2002 | Chinese Science Bulletin2002，47，10： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员