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| 1 | Occult hepatitis B virus infection among Egyptian blood donors显示文摘AIM:To identify blood donors with occult hepatitis B virus(HBV) infection(OBI) to promote safe blood donation.METHODS:Descriptive cross sectional study was conducted on 3167 blood donors negative for hepatitis B surface antigen(HBsAg),hepatitis C antibody(HCV Ab) and human immunodeficiency virus Ab.They were subjected to the detection of alanine aminotransferase(ALT) and aspartate transaminase(AST) and screening for anti-HBV core antibodies(total) by two different techniques;[Monoliza antibodies to hepatitis B core(Anti-HBc) Plus-Bio-Rad] and(ARC-HBc total-ABBOT).Positive samples were subjected to quantitative detection of antibodies to hepatitis B surface(anti-HBs)(ETI-AB-AUK-3,Dia Sorin-Italy).Serum anti-HBs titers > 10 IU/L was considered positive.Quantitative HBV DNA by real time polymerase chain reaction(PCR)(QIAGEN-Germany) with 3.8 IU/mL detection limit was estimated for blood units with negative serum anti-HBs and also for 32 whose anti-HBs serum titers were > 1000 IU/L.Also,265 recipients were included,34 of whom were followed up for 3-6 mo.Recipients were investigated for ALT and AST,HBV serological markers:HBsAg(ETI-MAK-4,Dia Sorin-Italy),anti-HBc,quantitative detection of anti-HBs and HBV-DNA.RESULTS:525/3167(16.6%) of blood units were positive for total anti-HBc,64% of those were antiHBs positive.Confirmation by ARCHITECT anti-HBc assay were carried out for 498/525 anti-HBc positive samples,where 451(90.6%) confirmed positive.Reactivity for anti-HBc was considered confirmed only if two positive results were obtained for each sample,giving an overall prevalence of 451/3167(14.2%) for total anti-HBc.HBV DNA was quantified by real time PCR in 52/303(17.2%) of anti-HBc positive blood donors(viral load range:5 to 3.5 x 105 IU/mL) with a median of 200 IU/mL(mean:1.8 x 104 ± 5.1 x 104 IU/mL).AntiHBc was the only marker in 68.6% of donors.Univariate and multivariate logistic analysis for identifying risk factors associated with anti-HBc and HBV-DNA positivity among blood donors showed that age above thirty and marriage were the most significant risk factors for prediction of anti-HBc positivity with AOR 1.8(1.4-2.4) and 1.4(1.0-1.9) respectively.Other risk factors as gender,history of blood transfusion,diabetes mellitus,frequent injections,tattooing,previous surgery,hospitalization,Bilharziasis or positive family history of HBV or HCV infections were not found to be associated with positive anti-HBc antibodies.Among anti-HBc positive blood donors,age below thirty was the most significant risk factor for prediction of HBV-DNA positivity with AOR 3.8(1.8-7.9).According to HBV-DNA concentration,positive samples were divided in two groups;group one with HBV-DNA ≥ 200 IU/mL(n = 27) and group two with HBV-DNA < 200 IU/mL(n = 26).No significant difference was detected between both groups as regards mean age,gender,liver enzymes or HBV markers.Serological profiles of all followed up blood recipients showed that,all were negative for the studied HBV markers.Also,HBV DNA was not detected among studied recipients,none developed post-transfusion hepatitis(PTH) and the clinical outcome was good.CONCLUSION:OBI is prevalent among blood donors.Nucleic acid amplification/HBV anti core screening should be considered for high risk recipients to eliminate risk of unsafe blood donation. | Zeinab N Said Manal H El Sayed Iman I Salama Enas K Aboel-Magd Magda H Mahmoud Maged El Setouhy Faten Mouftah Manal B Azzab Heidi Goubran Amal Bassili Gamal E Esmat | 2013 | World Journal of Hepatology2013，5，2： | 4 |
| 2 | Minimal electro-diagnostic criteria for chronic inflammatory demyelinating polyneuropathy (CIDP)显示文摘 | Magda P Latov N Brannagan TH | | 0，，： | 1 |
| 3 | Multifocal acquired sensory and motor neuropathy:electrodiagnostic features显示文摘 | Magda P Latov N Brannagan TH 3rd | 2005 | J Clin Neuromuscul Dis2005，7，1： | 1 |
| 4 | Quantitative sensory testing: high sensitivity in small fiber neuropathy with normal NCS/EMG显示文摘 | MAGDA P LATOV N RENARD M V | 2002 | J Peripher Nerv Syst2002，7，4： | 1 |
| 5 | Flagella and motility in Actinobacillus pleuropneumoniae 显示文摘 | ERASMO N A MAGDA E R ROSA M G | 2003 | Bacterioilogy2003，185，2： | 1 |
| 6 | Micellar properties of non-ionic surfactants in relation to their solubility parameters显示文摘 | Magda W S Viviane F N | 1988 | International Journal of Pharmaceutics1988，42，13： | 1 |
| 7 | Outlines for the definition of halotolerance/halophily in yeasts: Candida versatilis(haloph/la) CBS4019 as the archetype? 显示文摘 | Magda Silva-Graca Luisa N Candida L | 2003 | FEMS Yeast Research2003，3，4： | 1 |
| 8 | The effects of exchange rate fluctuations on economic activity in Turkey 显示文摘 | Kandil Magda Berument Hakan Dincer N Nergiz | 2007 | Journal of Asian Economics2007，18，3： | 1 |
| 9 | The effect of 'green' messages on brand purchase and brand rejection显示文摘 | Meagan W Anne S Magda N | 2013 | Aus- tralasian Marketing Journal2013，21，10： | 1 |
| 10 | Using Transient Elastography to Detect Chronic Liver Diseases in a Primary Care Nurse Consultancy显示文摘 | Núria Fabrellas Magda Alemany Marta Urquizu Concepció Bartres Guillem Pera Eulália Juvé Lluís Rodríguez Pere Torán Lloren? Caballería | 2013 | Nursing Research2013，，6： | 1 |
| 11 | Allogeneic adipose stem cell therapy in acute myocardial infarction显示文摘 | Montserrat Rigol Núria Solanes Santiago Roura Mercè Roqué Laura Novensà Ana Paula Dantas Jaume Martorell Marta Sitges José Ramírez Antoni Bayés‐Genís Magda Heras | 2014 | Eur J Clin Invest2014，，1： | 1 |
| 12 | High response rate and acceptable toxicity of a combination of rituximab, vinorelbine, ifosfamide, mitoxantrone and prednisone for the treatment of diffuse large B ‐cell lymphoma in first relapse: results of the R ‐ NIMP GOELAMS study显示文摘 | Emmanuel Gyan Diane Damotte Stéphane Courby Delphine Sénécal Philippe Quittet Aline Schmidt‐Tanguy Anne Banos Steven Gouill Thierry Lamy Jean Fontan Hervé Maisonneuve Magda Alexis Francois Dreyfus Olivier Tournilhac Kamel Laribi Philippe Solal‐Céligny Nin | 2013 | Br J Haematol2013，，2： | 1 |
| 13 | Evolution of the Socio-cognitive Structure of Knowledge Management(1986–2015): An Author Co-citation Analysis显示文摘Purpose: The evolution of the socio-cognitive structure of the field of knowledge management(KM) during the period 1986–2015 is described. Design/methodology/approach: Records retrieved from Web of Science were submitted to author co-citation analysis(ACA) following a longitudinal perspective as of the following time slices: 1986–1996, 1997–2006, and 2007–2015. The top 10% of most cited first authors by sub-periods were mapped in bibliometric networks in order to interpret the communities formed and their relationships.Findings: KM is a homogeneous field as indicated by networks results. Nine classical authors are identified since they are highly co-cited in each sub-period, highlighting Ikujiro Nonaka as the most influential authors in the field. The most significant communities in KM are devoted to strategic management, KM foundations, organisational learning and behaviour, and organisational theories. Major trends in the evolution of the intellectual structure of KM evidence a technological influence in 1986–1996, a strategic influence in 1997–2006, and finally a sociological influence in 2007–2015.Research limitations: Describing a field from a single database can offer biases in terms of output coverage. Likewise, the conference proceedings and books were not used and the analysis was only based on first authors. However, the results obtained can be very useful to understand the evolution of KM research.Practical implications: These results might be useful for managers and academicians to understand the evolution of KM field and to(re)define research activities and organisational projects.Originality/value: The novelty of this paper lies in considering ACA as a bibliometric technique to study KM research. In addition, our investigation has a wider time coverage than earlier articles. | Carlos Luis González-Valiente Magda León Santos Ricardo Arencibia-Jorge | 2019 | Journal of Data and Information Science2019，4，2： | 0 |
| 14 | Systemic Inflammation Response Index and weight loss as prognostic factors in metastatic pancreatic cancer: A concept study from the PANTHEIA-SEOM trial显示文摘BACKGROUND The prognostic value of the Systemic Inflammation Response Index(SIRI)in advanced pancreatic cancer is recognized,but its correlation with patients´nutritional status and outcomes remains unexplored.AIM To study the prognostic significance of SIRI and weight loss in metastatic pancreatic cancer.METHODS The PANTHEIA-Spanish Society of Medical Oncology(SEOM)study is a multicentric(16 Spanish hospitals),observational,longitudinal,non-interventional initiative,promoted by the SEOM Real World-Evidence work group.This pilot study sought to analyze the association between weight loss and inflammatory status as defined by SIRI.The cohort stems from a proof-of-concept pilot study conducted at one of the coordinating centers.Patients with pathologically confirmed metastatic pancreatic adenocarcinoma,treated from January 2020 to January 2023,were included.The index was calculated using the product of neutrophil and monocyte counts,divided by lymphocyte counts,obtained within 15 days before initiation chemotherapy.This study evaluated associations between overall survival(OS),SIRI and weight loss.RESULTS A total of 50 patients were included.66%of these patients were male and the median age was 66 years.Metastasis sites:36%liver,12%peritoneal carcinomatosis,10%lung,and 42%multiple locations.Regarding the first line palliative chemotherapy treatments:50%received gemcitabine plus nab-paclitaxel;28%,modified fluorouracil,leucovorin,irinotecan and oxaliplatin,and 16%were administered gemcitabine.42%had a weight loss>5%in the three months(mo)preceding diagnosis.21 patients with a SIRI≥2.3×10^(3)/L exhibited a trend towards a lower median OS compared to those with a SIRI<2.3×10^(3)/L(4 vs 18 mo;P<0.000).Among 21 patients with>5%weight loss before diagnosis,the median OS was 6 mo,in contrast to 19 mo for those who did not experience such weight loss(P=0.003).Patients with a weight loss>5%showed higher SIRI levels.This difference was statistically significant(P<0.000).For patients with a SIRI<2.3×10^(3)/L,those who did not lose>5%of their weight had an OS of 20 mo,compared to 11 mo for those who did(P<0.001).No association was found between carbohydrate antigen 19-9 levels≥1000 U/mL and weight loss.CONCLUSION A higher SIRI was correlated with decreased survival rates in patients with metastatic pancreatic cancer and associated with weight loss.An elevated SIRI is suggested as a predictor of survival,emphasizing the need for prospective validation in the upcoming PANTHEIA-SEOM study. | Vilma Pacheco-Barcia Sara Custodio-Cabello Fatima Carrasco-Valero Magda Palka-Kotlowska Axel Mariño-Mendez Alberto Carmona-Bayonas Javier Gallego A J Muñoz Martín Paula Jimenez-Fonseca Luis Cabezon-Gutierrez | 2024 | World Journal of Gastrointestinal Oncology2024，16，2： | 0 |
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