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| 1 | Combination of corticosteroids and 5-aminosalicylates or corticosteroids alone for patients with moderate-severe active ulcerative colitis:A global survey of physicians'practice显示文摘AIM To examine treatment decisions of gastroenterologists regarding the choice of prescribing 5-aminosalycilates(5ASA) with corticosteroids(CS) versus corticosteroids alone for patients with active ulcerative colitis(UC). METHODS A cross-sectional questionnaire exploring physicians' attitude toward 5ASA + CS combination therapy vs CS alone was developed and validated. The questionnaire was distributed to gastroenterology experts in twelve countries in five continents. Respondents' agreement with stated treatment choices were assessed by standardized Likert scale. Background professional characteristics of respondents were analyzed for correlation with responses. RESULTS Six hundred and sixty-four questionnaires were distributed and 349 received(52.6% response rate). Of 340 eligible respondents, 221(65%) would continue 5ASA in a patient hospitalized for intravenous CS treatment due to a moderate-severe UC flare, while 108(32%) would stop the 5ASA(P < 0.001), and 11(3%) are undecided. Similarly, 62% would continue 5ASA in an out-patient starting oral CS. However, only 140/340(41%) would proactively start 5ASA in a hospitalized patient not receiving 5ASA before admission. Most(94%) physicians consider the safety profile of 5ASA as very good. Only 52% consider them inexpensive, 35% perceive them to be expensive and 12% are undecided. On multi-variable analysis, less years of practice and perception of a plausible additive mechanistic effect of 5ASA + CS were positively associated with the decision to continue 5ASA with CS. CONCLUSION Despite the absence of data supporting its benefit, most gastroenterologists endorse combination of 5ASA + CS for patients with active moderate-to-severe UC. Randomized controlled trials are needed to assess if 5ASA confer any benefit for these patients. | Shomron Ben-Horin Jane M Andrews Konstantinos H Katsanos Florian Rieder Flavio Steinwurz Konstantinos Karmiris Jae Hee Cheon Gordon William Moran Monica Cesarini Christian D Stone Doron Schwartz Marijana Protic Xavier Roblin Giulia Roda Min-Hu Chen Ofir Har-Noy Charles N Bernstein | 2017 | World Journal of Gastroenterology2017，23，16： | 3 |
| 2 | Testing for HCV Infection: An Update of Guidance for Clinicians and Laboratorians显示文摘 | Getchell Jane P Wroblewski Kelly E DeMaria Alfred Bean Christine L Parker Monica M Pandori Mark Dufour D Robert Busch Michael P Brecher Mark E Meyer William A Pesano Rick L Teo Chong-Gee Beckett Geoffrey A Araujo Aufra C Branson Bernard M D | 2013 | MMWR. Morbidity and Mortality Weekly Report2013，，18： | 3 |
| 3 | Short- Versus Long-Term Duration of Dual-Antiplatelet Therapy After Coronary Stenting: A Randomized Multicenter Trial显示文摘 | Marco Valgimigli Gianluca Campo Monia Monti Pascal Vranckx Gianfranco Percoco Carlo Tumscitz Fausto Castriota Federico Colombo Matteo Tebaldi Giuseppe Fucà Moh?d Kubbajeh Elisa Cangiano Monica Minarelli Antonella Scalone Caterina Cavazza Alice Frangione M | 2012 | Circulation2012，，16： | 1 |
| 4 | Performance comparison of Gaussian-based filters using information measures显示文摘 | MAHESH V MONICA F B Petar M D | 2007 | IEEE Signal Processing Letters2007，14，12： | 1 |
| 5 | Missing OH reactivity in a forest : evidence for unknown reactive biogenic VOCs 显示文摘 | Piero D C William H B Monica M | 2004 | Science2004，304，5671： | 1 |
| 6 | Synthesis and characterization of Ti1-2xNbxNixO2-x/2 solid solutions显示文摘 | Monica M Beatriz J Hakim D | 2007 | Journal of Solid State Chemistry2007，，180： | 1 |
| 7 | Effect of human chorionic gonadctrophin supplementation during different culture periods on in viro maturation of canine oocytes显示文摘 | Monica D R Johanna D L Pedro M | 2005 | Theriogenology2005，64，： | 1 |
| 8 | Shape and size of micelles in the sodium dodecyl sul fate-formamide system显示文摘 | CEGLIE A COLAFEMMINA G MONICA M D | 1993 | Langmuir1993，9，： | 1 |
| 9 | Electrochemical and Spectroscopic Studies of Cytoehrome c Immoblized in Polypyrrole Films显示文摘 | Caselli M Monica M D Portacci M | 1991 | Journal of Electroanalytical Chemistry1991，319，12： | 1 |
| 10 | Synthesis and characterization of CdS nanoclusters in a quarternary mieroemulsion: The role of the eosurfaetant 显示文摘 | CURRI M L AGOSTIANO A MANNA L MONICA M D CATALANO M CHINARARONA L SPAGNOLO V LUGARA M | 2000 | J Phys Chem B2000，104，： | 1 |
| 11 | ISBAR for clear communica- tion:one hospital's experience spreading the message显示文摘 | Monica A F Stuart D M Brendan T F | 2010 | Australian Health Review2010，34，4： | 1 |
| 12 | Shape and size of micelles in the sodium dodecyl sulfate-formamide system显示文摘 | CEGLIE A COLAFEMMINA G MONICA M D | 1993 | Langmuir1993，9，： | 1 |
| 13 | Ward IFN-γ Is the Only Anti-rotavirus Cytokine Found after In Vitro Stimulation of Memory CD4^+ T Cells from Mice Immunized with a Chimeric VP6 Protein显示文摘 | Monica M McNeal Susan C Stone Mitali Basu John D | 2007 | Viral Immunology2007，6，2： | 1 |
| 14 | Screening for anthocyanins using high- performance liquid chromatography coupled to electrospray ionization tandem mass spectrometry with precursor-ion analysis, product- ion analysis, common- neutral- loss analysis, and selected reaction monitoring 显示文摘 | Tian Q G Monica Giusti M Stoner G D | 2005 | Journal of Chromatography A2005，1091，： | 1 |
| 15 | Degradation of procyanidins by Aspergillus fumigatus: Identification of a novel aromatic ring cleavage product 显示文摘 | Monica C D Sylvain G Nathalie M | 2006 | Biochimie2006，88，12： | 1 |
| 16 | Combination of Gefitinib and?Pemetrexed?Prevents the Acquisition of TKI Resistance in NSCLC Cell Lines Carrying EGFR-Activating Mutation显示文摘 | La Monica S Madeddu D Tiseo M | 2016 | Thorac Oncol2016，，16： | 1 |
| 17 | A novel two bases deletion in the albumin gene causes analbuminaemia in a young Turkish man显示文摘 | Gianluca C Monica D Marco D D Filiz A Gungor B Fatih B Kadir D Asli O Suut G Kivanc C Sukru O Sukru P Monica C Monica G Lorenzo M | | 0，，9： | 1 |
| 18 | The Molecular Basis for the Evolution of the Metazoan Bodyplan: Extracellular Matrix-Mediated Morphogenesis in Marine Demosponges显示文摘 | Matthias Wiens Alfonso Mangoni Monica D’Esposito Ernesto Fattorusso Natalia Korchagina Heinz C. Schr?der Vladislav A. Grebenjuk Anatoli Krasko Renato Batel Isabel M. Müller Werner E. G. Müller | 2003 | Journal of Molecular Evolution2003，，1： | 1 |
| 19 | Water tolerance and ethanol concentration in ethanol-gasoline fuels at three temperatures 显示文摘 | Monica B Gramajo de D Carlos M B | 2004 | Energy & Fuels2004，18，： | 1 |
| 20 | Effect of human chorionic gonadotrophin supplementation during different culture periods on in vitro maturation of canine oocytes显示文摘 | Monica D R Johanna D L Pedro M | 2005 | Theriogenology2005，64，： | 1 |
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