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| 1 | 利用洋底地震资料估算进入马里亚纳俯冲带的水通量显示文摘俯冲带水迁移是地表水进入地球深部的主要方式。但是,通过板块俯冲到底能够带入深部地幔多少水受到多种因素影响,包括俯冲带板片年龄、俯冲带几何性质、俯冲带热结构、板块汇聚速率等。目前关于俯;中带的水循环仍知之甚少。最近,华盛顿大学地球与行星科学系的Cai C博士等人收集和分析了马里亚纳海沟中心周围宽频洋底瑞利面波地震数据,估算了通过板块俯冲输入地球深部的水通量。他们的研究结果表明:板块俯冲带入深部地幔的水通量是以前估算的4.3倍,而且远大于目前对地幔输出水通量的估计。由于大量的长期净水流入地球深处与地质记录中的海平面稳定性不一致;同时也没有迹象表明马里亚纳俯冲带的板块弯曲区在形态和断裂强度与其它古俯冲带的对应区域对比有很大的不同。 | Cai C Wiens D A Shen W Eimer M 张宝华 | 2018 | 矿物岩石地球化学通报2018，37，6： | 13 |
| 2 | Missing data and the accuracy of Bayesian phylogenetics显示文摘The effect of missing data on phylogenetic methods is a potentially important issue in our attempts to reconstruct the Tree of Life. If missing data are truly problematic, then it may be unwise to include species in an analysis that lack data for some characters (incomplete taxa) or to include characters that lack data for some species. Given the difficulty of obtaining data from all characters for all taxa (e.g., fossils), missing data might seriously impede efforts to reconstruct a comprehensive phylogeny that includes all species. Fortunately, recent simulations and empirical analyses suggest that missing data cells are not themselves problematic, and that in-complete taxa can be accurately placed as long as the overall number of characters in the analysis is large. How-ever, these studies have so far only been conducted on parsimony, likelihood, and neighbor-joining methods. Although Bayesian phylogenetic methods have become widely used in recent years, the effects of missing data on Bayesian analysis have not been adequately studied. Here, we conduct simulations to test whether Bayesian analyses can accurately place incomplete taxa despite extensive missing data. In agreement with previous studies of other methods, we find that Bayesian analyses can accurately reconstruct the position of highly incomplete taxa (i.e., 95% missing data), as long as the overall number of characters in the analysis is large. These results suggest that highly incomplete taxa can be safely included in many Bayesian phylogenetic analyses. | John J. WIENS Daniel S. MOEN | 2008 | 植物分类学报2008，46，3： | 2 |
| 3 | Ambrisentan for the Treatment of Pulmonary Arterial Hypertension: Results of the Ambrisentan in Pulmonary Arterial Hypertension, Randomized, Double-Blind, Placebo-Controlled, Multicenter, Efficacy (ARIES) Study 1 and 2显示文摘 | Nazzareno Galiè Horst Olschewski Ronald J. Oudiz Fernando Torres Adaani Frost Hossein A. Ghofrani David B. Badesch Michael D. McGoon Vallerie V. McLaughlin Ellen B. Roecker Michael J. Gerber Christopher Dufton Brian L. Wiens Lewis J. Rubin | 2008 | Circulation2008，，23： | 2 |
| 4 | Helium isotope diffusion in natural diamonds 显示文摘 | Wiens R C | 1994 | Geochim Cosmochim Acta1994，58，： | 2 |
| 5 | High water solubility and fold in amphipols of proteins with large hydrophobic regions: Oleosins and caleosin from seed lipid bodies显示文摘 | Yann Gohon Jean-David Vindigni Agnès Pallier Frank Wien Hervé Celia Alexandre Giuliani Christophe Tribet Thierry Chardot Pierre Briozzo | 2010 | BBA - Biomembranes2010，，3： | 2 |
| 6 | 高速连铸用新型浸入式水口显示文摘连铸机结晶器内钢液的流动状态严重影响连铸坯的质量,尤其在弯月面处,钢液与结晶器保护渣直接接触,结晶器内弯月面不稳定引起的卷渣,是导致产品产生缺陷的主要原因之一,如冷轧薄板的线状缺陷和厚板的表面缺陷。在结晶器润滑不均匀时,还会增加漏钢危险。弯月面液面波动主要是由于浸入式水口吐出孔钢液剧烈的湍流和瞬态行为引起的。最近,在一台连铸机上浇注不同钢种已成为全世界钢铁生产商努力的一个主要方向。为了满足所有钢种的质量要求,对每个钢种都要求一定的浇注速度。对常规的浸入式水口而言,确保结晶器内有利的流动条件是一个难题。因此,比以往更需要一种新型浸入式水口,通过保持最佳的结晶器内钢液流动状态,以各种浇注速度浇注出多规格铸坯。介绍了测试新型浸入式水口流动性能的数值模型和物理模型的试验。采用URANS方法瞬态CFD模拟表明,新型浸入式水口流出的钢液瞬态行为稳定,因而弯月面以下钢液流速较慢,其效果还通过水模拟得到了验证。现场试验是在中国台湾的中钢公司进行的,试验结果表明,通过优化结晶器内钢液的流动行为,结晶器液面波动明显减小,从而提高了产品质量。 | Shung Sheng Kao Hsin Chin Kua Oliver Wiens Wolfgang Mo?ner Markus Reifferscheid Nobert Vogl Gernot Hackl Gerald Nitzl 潘秀兰 | 2014 | 世界钢铁2014，，1： | 2 |
| 7 | Factors associated with 5-year survival of combined hepatocellular and cholangiocarcinoma显示文摘BACKGROUND Combined hepatocellular and cholangiocarcinoma(HCC/CC)is a rare primary hepatic malignancy which carries a poor prognosis due to its aggressive nature.Few centers have enough cases to draw definitive conclusions and there is limited understanding of prognosis.Given the rarity of HCC/CC,an analysis of large national cancer database was needed to obtain larger number of HCC/CC cases.AIM To identify associated factors for 5-year survival of HCC/CC.METHODS We conducted a retrospective study of The Surveillance,Epidemiology,and End Results(SEER)database obtained from SEER*Stat 8.3.6 software.Previously defined histology code 8180 for the International Classification of Disease for Oncology,3rd edition was used to identify HCC/CC cases from 2004 to 2015.We collected demographics,American Joint Committee on Cancer(AJCC)stage,treatment,tumor size,and survival data.These data were converted to categorical variables.The Shapiro-Wilk normality test was used to assess normal distribution.Mann-Whitney U test was used to compare continuous variables without normal distribution,and t-test was used to compare continuous variables with a normal distribution.The Kaplan-Meier survival curve analyzed 5-year survival.Univariate and multivariate logistic regression model was used to analyze factors associated with 5-year survival.Multivariate Cox proportional hazard regression was done on 5-year survival.We defined P<0.05 was statistically significant.RESULTS We identified 497 patients with the following characteristics:Mean age 62.4 years(SD:11.3),149(30.0%)were female,racial distribution was:276(55.5%)white,53(10.7%)black,84(16.9%)Asian and Pacific Islander(API),77(15.5%)Hispanic,and 7(1.4%)others or unknown.Stage I/II disease occurred in 41.5%and tumor size<50 mm was seen in 35.6%of patients.Twenty-four(4.8%)received locoregional therapy(LRT),119(23.9%)underwent resection,and 50(10.1%)underwent liver transplantation.The overall median survival was 6 mo[Interquartile range(IQR):1-22].After multivariate logistic regression,tumor size<50 mm[Odds ratios(OR):2.415,P=0.05],resection(OR:12.849,P<0.01),and transplant(OR:27.129,P<0.01)showed significance for 5-year survival.Age>60,sex,race,AJCC stages,metastasis,and LRT were not significant.However,API vs white showed significant OR of 2.793(CI:1.120-6.967).Cox proportional hazard regression showed AJCC stages,tumor size<50 mm,LRT,resection,and transplant showed significant hazard ratio.CONCLUSION HCC/CC patients with tumor size<50 mm,resection,and transplant were associated with an increase in 5-year survival.API showed advantageous OR and hazard ratios over white,black. | Tomoki Sempokuya Eric A Wien Robert J Pattison Jihyun Ma Linda L Wong | 2020 | World Journal of Hepatology2020，12，11： | 2 |
| 8 | Cerebellar hemorrhage and cerebellar infarct:Retrospective study of 125 cases显示文摘 | Wien M Landers R J Koffa M | 1993 | Wochenschr1993，143，6： | 1 |
| 9 | Partial ordering of life distributions with respect to their aging properties显示文摘 | Kochar S C Wiens D P | 1987 | Naval Research Logistics Quarterly1987，34，： | 1 |
| 10 | Local and regional-scale responses of ant diversity to a semiarid biome transition zone 显示文摘 | Bestelmeyer B T Wiens J A | 2001 | Ecography2001，24，： | 1 |
| 11 | A fixed sequence Bonferroni procedure for testing multiple endpoints 显示文摘 | WIENS BL | 2003 | Pharm Statis2003，2，3： | 1 |
| 12 | Treatment of lower urinary tract infection caused by multidrug-resistant extended-spectrum-β-lactamase-producing Escherichia coli with amoxicillin/clavulanate:case report and characterization of the isolate显示文摘 | Lagacé-Wiens PR Nichol KA Nicolle LE | 2006 | J Antimicrob Chemother2006，57，： | 1 |
| 13 | Methylmercury in aquatic insects from an experimental reservoir显示文摘 | Hall B D Rosenberg D M Wiens A P | 1998 | Can J Fish Aquat Sci1998，55，： | 1 |
| 14 | Early effects on endothelial function of atorvastatin 40 mg twice daily and its withdrawal显示文摘 | Taneva E Borucki K Wiens L | 2006 | Am J Cardiol2006，97，7： | 1 |
| 15 | Monoclonal antibodies to the E2 protein of a new genotype of bovine viral virus define three antigenic domains involved in neutralization显示文摘 | Deregt D van Rijn P A Wiens T Y | 1998 | Virus Res1998，57，： | 1 |
| 16 | Isoprenoid-mediated changes in the glycerophospholipid molecular species of the sterol auxotrophic fungus Lagenidium giganteum显示文摘 | Kerwin JL Tuininga AR Wiens AM | 1995 | Microbiology1995，141，2： | 1 |
| 17 | Patterns of fine root mass and distribution along a disturbance gradient in a tropical montane forest,central Sulawesi(Indonesia)显示文摘 | Leuschner C Wiens M Harteveld M | 2006 | Plant and Soil2006，283，： | 1 |
| 18 | Spatial scaling in ecology显示文摘 | | 1989 | Functional Ecology1989，3，： | 1 |
| 19 | Comparison of nonlinear height-diameter functions for major Alberta tree species 显示文摘 | Huang S Titus S J Wiens D P | 1992 | Canadian Journal of Forest Research1992，22，： | 1 |
| 20 | Validation of FLT uptake as a measure of thymidine kinase-I activity in A549 carcinoma ceils 显示文摘 | Rasey JS Grierson JR Wiens LW | 2002 | JNuclMed2002，43，9： | 1 |
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