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| 1 | Endoscopic management of gastrointestinal perforations, leaks and fistulas显示文摘Gastrointestinal perforations, leaks and fistulas may be serious and life-threatening. The increasing number of endoscopic procedures with a high risk of perforation and the increasing incidence of leakage associated with bariatric operations call for a minimally invasive treatment for these complications. The therapeutic approach can vary greatly depending on the size,location, and timing of gastrointestinal wall defect recognition. Some asymptomatic patients can be treated conservatively, while patients with septic symptoms or cardio-pulmonary insufficiency may require intensive care and urgent surgical treatment.However, most gastrointestinal wall defects can be satisfactorily treated by endoscopy. Although the initial endoscopic closure rates of chronic fistulas is very high, the long-term results of these treatments remain a clinical problem. The efficacy of endoscopic therapy depends on several factors and the best mode of treatment will depend on a precise localization of the site, the extent of the leak and the endoscopic appearance of the lesion. Many endoscopic tools for effective closure of gastrointestinal wall defects are currently available. In this review, we summarized the basic principles of the management of acute iatrogenic perforations, as well as of postoperative leaks and chronic fistulas of the gastrointestinal tract. We also described the effectiveness of various endoscopic methods based on current research and our experience. | Pawel Rogalski Jaroslaw Daniluk Andrzej Baniukiewicz Eugeniusz Wroblewski Andrzej Dabrowski | 2015 | World Journal of Gastroenterology2015，21，37： | 8 |
| 2 | Testing for HCV Infection: An Update of Guidance for Clinicians and Laboratorians显示文摘 | Getchell Jane P Wroblewski Kelly E DeMaria Alfred Bean Christine L Parker Monica M Pandori Mark Dufour D Robert Busch Michael P Brecher Mark E Meyer William A Pesano Rick L Teo Chong-Gee Beckett Geoffrey A Araujo Aufra C Branson Bernard M D | 2013 | MMWR. Morbidity and Mortality Weekly Report2013，，18： | 3 |
| 3 | Mutations in the human retinal degeneration slow (RDS) gene can cause either retinitis pigmentosa or macular dystrophy显示文摘 | Wroblewski J Keen J | 1993 | Nat Genet1993，3，： | 1 |
| 4 | Differential effects of oral losartan and enalapril on local venous and systemic pressor responses to angiotenain Ⅰ and Ⅱ in healthy men显示文摘 | Goldberg MR DE Mey C Wroblewski JM | 1996 | Clin Pharmacol Ther1996，59，： | 1 |
| 5 | The recognition of beer with flow-through sensor array based on miniaturized solidstate electrodes显示文摘 | P Ciosek W Wroblewski | 2006 | Talanta2006，69，： | 1 |
| 6 | Application of platelet-rich plasma to enhance tissue repair显示文摘 | Wroblewski AP Mejia HA Wright VJ | 2010 | Oper Tech Orthop2010，20，2： | 1 |
| 7 | Pegaptanib sodium for macular edema secondary to central retinal vein occlusion显示文摘 | Wroblewski JJ Wells JA 3 rd Adamis AP | | 0，，： | 1 |
| 8 | Optimization of Agrobacte- rium-mediated transient assays of gene expression in lettuce,toma- to and Arabidopsis显示文摘 | WROBLEWSKI T MICHELMORE R | 2005 | Plant Biotechnology Journal2005，3，2： | 1 |
| 9 | Characterization of human non-small cell lung cancer (NSCLC) cell lines for expression of MHC,co-stimulatory molecules and tumor-associated antigens显示文摘 | Wroblewski JM Bixby DL Borowski C | 2001 | Lung Cancer2001，33，23： | 1 |
| 10 | A brief survey of patients' first impression afterCPAP titration predicts future CPAP adherence:a pi-lot study显示文摘 | BALACHANDRAN J S YU X WROBLEWSKI K etal | 2013 | Clin Sleep Med2013，9，： | 1 |
| 11 | Characterization of human non-small cell lung cancer (NSCLC) cell lines for expres- sion of MHC, co-stimulatory molecules and tumor-associated anti- gens显示文摘 | Wroblewski JM Bixby DL Borowski C | 2001 | Lung Cancer2001，33，23： | 1 |
| 12 | Computer-aided de-tection of artificial pulmonary nodules using an ex vivo lung phan-tom: influence of exposure parameters and iterative reconstruction显示文摘 | Wielpiitz MO Wroblewski J Lederlin M | 2015 | Eur J Radiol2015，84，： | 1 |
| 13 | p120 and Kaiso regulate Helicobacter pylori - induced expression of matrix metallo- proteinase -7显示文摘 | Ogden SR Wroblewski LE Weydig C | 2008 | Mol Biol Cell2008，19，10： | 1 |
| 14 | Multiple requirements for Hes 1 during early eye formation 显示文摘 | Lee HY Wroblewski E Philips GT Stair CN Conley K Reedy M | 2005 | Dev Biol2005，284，2： | 1 |
| 15 | Trans - specific gene silencing betiveen host and parasitic plants 显示文摘 | Tomilov A A Tomilova N B Wroblewski T | 2008 | The Plant Journal2008，56，3： | 1 |
| 16 | Determining optimal surface roughness of Ti02 blasted titanium implant material for attachment, proliferation and differentiation of cells derived from human mandibular alveolar bone 显示文摘 | Mustafa K Wennerberg A Wroblewski J | 2001 | Clin Oral Implants Res2001，12，5： | 1 |
| 17 | Macular dystrophy associated with mutations at codon 172 in the human retinal degeneration slow gene显示文摘 | Wells JA Eckstein A | 1994 | Ophthalmology1994，101，： | 1 |
| 18 | One-stage revision of infected total hip replacements with discharging sinuses显示文摘 | Raut VV Siney PD Wroblewski BM | 1994 | J Bone Joint Surg[Br]1994，76，： | 1 |
| 19 | Binding of insulinlike growth factor-1 ( IGF-1 ) to primary cultures of chondrocytes from rats rib growth cartilage 显示文摘 | Makower A M Skotter A Wroblewski J | 1989 | Cell Biol Int Rep1989，13，5： | 1 |
| 20 | Fatal pulmonary em- bolism and mortality after revision of failed total hip arthroplasties 显示文摘 | Wroblewski BM Siney PD Fleming PA | 2000 | J Arthroplasty2000，15，4： | 1 |
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