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| 1 | Numerical simulation and experimental investigation of natural convection heat transfer of molten salt around fine wire显示文摘In order to get the natural convection heat transfer mechanism of molten salt, the experimental investigation of natural convective heat transfer of LiNO3was studied after it was simulated by numerical calculation. Experiment was carried out on the nat-ural convection heat transfer of air and water around the fine wire using the method of Joule heating. The results showed that the natural convection heat transfer of air and water around the fine wire agreed well with Fand's correlation. Based on the aforementioned experiment, the natural convection heat transfer of molten salt LiNO3was studied by experiment and the same results were got. Therefore, the natural convection heat transfer of molten salt can be calculated by Fand's correlation, which takes into consideration the effect of viscosity dissipation. | LU YuanWei LI XiaoLi LI Qiang WU YuTing MA ChongFang | 2013 | Science China(Technological Sciences)2013，56，7： | 13 |
| 2 | 3D bioprinting: an emerging technology full of opportunities and challenges显示文摘 | Bin Zhang Yichen Luo Liang Ma Lei Gao Yuting Li Qian Xue Huayong Yang Zhanfeng Cui | 2018 | Bio-Design and Manufacturing2018，1，1： | 13 |
| 3 | Surface ozone monitoring and background characteristics at Zhongshan Station over Antarctica显示文摘Seasonal variation in surface ozone and the relationship between the background ozone concentration and wind were evaluated at Zhongshan Station,Antarctica using 2008 data.The wind frequency from the station area was only 2%,while the prevailing wind frequency was much larger (79.2%).This indicates that the surface ozone observations were not affected by the human activities at the station,and therefore could be counted as background concentrations of surface ozone along Antarctic coast.The concentration of surface ozone shows a distinct annual variation with the yearly mean of 25.0 nmol mol-1 and the maximum in winter,the minimum in summer.The surface ozone concentration had a strong negative correlation with ultraviolet radiation,and the mean values during polar night were one to two times higher than those in summer.These results imply that photochemical destruction of ozone dominates over Antarctica.The ozone depletion events at Zhongshan Station were obviously related to lower temperatures and higher BrO concentrations.Backward trajectory analysis reveals that the ozone depletion events are predominately caused by the high BrO concentrations. | WANG YuTing BIAN LinGen MA YongFeng TANG Jie ZHANG DongQi ZHENG XiangDong | 2011 | Chinese Science Bulletin2011，56，10： | 7 |
| 4 | Natural convection heat transfer of molten salt in a single energy storage tank显示文摘在在一辆柱体坦克的熔融的盐的热转移经由模拟和实验被学习在一辆单个精力存储坦克获得它的自然传送对流热转移。模拟和在一辆柱体坦克的水的自然传送对流热转移与 Garons 关联适合很好的试验性的结果表演。然而,当因为它的高粘性和低热电导率, Garons 关联被用来预言熔融的盐的自然传送对流热转移时,重要偏差发生。然而,熔融的盐的自然传送对流热转移的模仿的数据试验性的结果与那些适合很好。因此,考虑可变物理性质的效果的关联在这研究被建议预言熔融的盐的自然传送对流热转移。从建议关联的现在的数据的偏差是不到 d 控制模拟。在 summe 枼 ? 枼期间?? | LU YuanWei YU Qiang DU WenBin WU YuTing MA ChongFang | 2016 | Science China(Technological Sciences)2016，59，8： | 7 |
| 5 | Effects of Straw Incorporation Methods on Nitrous Oxide and Methane Emissions from a Wheat-Rice Rotation System显示文摘The incorporation of straw with a microbial inoculant(a mixture of bacteria and fungi, designed to accelerate straw decomposition)is being increasingly adopted within the agricultural sector in China. However, its effects on N and C trace gas emissions remain unclear.We conducted a field experiment to investigate the effects of different straw incorporation methods(with and without microbial inoculant) in the wheat season on nitrous oxide(N_2O) and methane(CH_4) emissions from a wheat-rice rotation system in China.The treatments comprised N, P, and K fertilizers only(NPK), NPK plus rice straw(NPKS), NPKS plus Ruilaite microbial inoculant(NPKSR), and NPKS plus Jinkuizi microbial inoculant(NPKSJ). Rice straw incorporation before wheat sowing significantly decreased N_2O emissions during the wheat season and stimulated N_2O and CH_4 emissions during the subsequent rice season. Compared with the NPKS treatment, the NPKSR and NPKSJ treatments decreased N_2O emissions during the wheat season, but had no effect on N_2O or CH_4 emissions during the subsequent rice season. Annually, the two treatments were comparable regarding N_2O emissions.Although the global warming potentials of the NPKSR and NPKSJ treatments were lower than that of the NPKS treatment during the wheat season, no significant differences were observed during the subsequent rice season, or over the entire rotation cycle. The annual greenhouse gas intensity was slightly lower in the NPKSR and NPKSJ treatments than in the NPKS treatment. Overall, these results suggest that the incorporation of rice straw with a microbial inoculant in the wheat season was the best strategy tested for managing straw resources within the wheat-rice rotation system. | LIU Gang MA Jing YANG Yuting YU Haiyang ZHANG Guangbin XU Hua | 2019 | Pedosphere2019，29，2： | 7 |
| 6 | Variations of Stable Carbon Isotopes of CH4 Emission from Three Typical Rice Fields in China显示文摘Little is known about the stable carbon isotopes of methane(CH4) emitted(δ^(13)CH_(4emitted)) from permanently flooded rice fields and double rice-cropping fields.The CH4 emission and corresponding δ^(13)CH_(4emitted) under various field managements(mulching,water regime,tillage,and nitrogen(N) fertilization) were simultaneously measured in three typical Chinese rice fields,a permanently flooded rice field in Ziyang City,Sichuan Province,Southwest China,a double-rice cropping field in Yingtan City,Jiangxi Province,Southeast China,and a rice-wheat rotation field in Jurong City,Jiangsu Province,East China,from 2010 to 2012.Results showed different seasonal variations of δ^(13)CH_(4emitted) among the three fields during the rice-growing season.The values of δ^(13)CH_(4emitted) were negatively correlated with corresponding CH4 emissions in seasonal variation and mean,indicating the importance of CH_4 production,oxidation,and transport associated with isotopic fractionation effects to the δ^(13)CH_(4emitted).Seasonal variations of δ^(13)CH_(4emitted) were slightly impacted by mulching cultivation,tillage,and N application,but highly controlled by drainage.Meanwhile,tillage,N application,and especially mulching cultivation had important effects on seasonal mean CH4 emissions and corresponding δ^(13)CH_(4emitted) with low emissions accompanied by high values of δ^(13)CH_(4emitted).Seasonal mean values of δ^(13)CH_(4emitted) from the three fields were similar,mostly ranging from —60‰ to — 50‰,which are well in agreement with previously published data.These demonstrated that seasonal variations of δ^(13)CH_(4emitted) mainly depended on the changes in CH4 emission from rice fields and further indicated the important effects of methanogenic pathways,CH4 oxidation,and CH4 transport associated with isotope fractionation effects influenced by field managements on δ^(13)CH_(4emitted). | ZHANG Guangbin MA Jing YANG Yuting YU Haiyang SHI Yaping XU Hua | 2017 | Pedosphere2017，27，1： | 6 |
| 7 | Genome-and transcriptome-wide association studies provide insights into the genetic basis of natural variation of seed oil content in Brassica napus显示文摘Seed oil content(SOC)is a highly important and complex trait in oil crops.Here,we decipher the genetic basis of natural variation in SOC of Brassica napus by genome-and transcriptome-wide association studies using 505 inbred lines.We mapped reliable quantitative trait loci(QTLs)that control SOC in eight environments,evaluated the effect of each QTL on SOC,and analyzed selection in QTL regions during breeding.Six-hundred and ninety-two genes and four gene modules significantly associated with SOC were identified by analyzing population transcriptomes from seeds.A gene prioritization framework,POCKET(prioritizing the candidate genes by incorporating information on knowledge-based gene sets,effects of variants,genome-wide association studies,and transcriptome-wide association studies),was implemented to determine the causal genes in the QTL regions based on multi-omic datasets.A pair of homologous genes,BnPMT6s,in two QTLs were identified and experimentally demonstrated to negatively regulate SOC.This study provides rich genetic resources for improving SOC and valuable insights toward understanding the complex machinery that directs oil accumulation in the seeds of B.napus and other oil crops. | Shan Tang Hu Zhao Shaoping Lu Liangqian Yu Guofang Zhang Yuting Zhang Qing-Yong Yang Yongming Zhou Xuemin Wang Wei Ma Weibo Xie Liang Guo | 2021 | Molecular Plant2021，14，3： | 6 |
| 8 | Integrated genomic analysis identifies deregulated JAK/STAT-MYC-biosynthesis axis in aggressive NK-cell leukemia显示文摘好攻击的 NK 房间白血病(ANKL ) 是在从亚洲的人之中是更流行的 NK 房间瘤的一种稀罕形式并且中央并且南美洲。病人们通常在天以内死到月,甚至在收到迅速的治疗学的管理以后。这里,我们由集成整个染色体执行了 ANKL 的第一全面研究, transcriptome 并且定序指向,象功能的试金一样的 cytokine 数组。在 JAK-STAT 小径的变化在 48% 被识别(14/29 ) ANKL 病人,当细胞外的 STAT3 激发器 IL10 被 56 褶层的一般水准提高时(P < 0.0001 ) 在检查的所有病人的血浆。另外的经常变异的基因包括的 TP53 (34%) , TET2 (28%) , CREBBP (21%) 和 MLL2 (21%) 。耐心的 NK 白血病房间在多重新陈代谢的小径显示出 STAT3 phosphorylation, MYC 表示和 transcriptional 活动的突出的激活。机能上地, STAT3 激活和 MYC 表示为 ANKL 房间的增长和幸存是批评的。发信号的 STAT 调整了发信号的 MYC 抄写节目,和两 STAT, MYC 抄写被要求维持核苷酸合成和 glycolysis 的激活。一起, JAK-STAT 小径在 ANKL 为 genomic 改变和 IL10 刺激代表一个主要目标。这最新发现的 JAK/STAT-MYC-biosynthesis 轴可以在对待白血病的这种子类型为新奇治疗学的策略的发展提供机会。 | Liang Huang Dan Liu Na Wang Shaoping Ling Yuting Tang Jun Wu Lingtong Hao Hui Luo Xuelian Hu Lingshuang Sheng Lijun Zhu Di Wang Yi Luo Zhen Shang Min Xiao Xia Mao Kuangguo Zhou Lihua Cao Lili Dong Xinchang Zheng Pinpin Sui Jianlin He Shanlan Mo Jin Yan Qilin Ao Lugui Qiu Hongsheng Zhou Qifa Liu Hongyu Zhang Jianyong Li Jie Jin Li Fu Weili Zhao Jieping Chen Xin Du Guoliang Qing Hudan Liu Xin Liu Gang Huang Ding Ma Jianfeng Zhou Qian-fei Wang | 2018 | Cell Research2018，28，2： | 5 |
| 9 | Experimental study of viscosity characteristics of hightemperature heat transfer molten salts显示文摘In this paper several kinds of high temperature molten salts were investigated experimentally on viscosity-temperature characteristics with high-temperature viscometer.The viscosities of the molten salts were measured and compared with those from references to verify the reliability of the viscometer and measuring methods,and a good agreement was observed from the comparisons.Then,two new high-temperature molten salts were made from the HITEC salt by some additives and the viscosity-temperature profiles of them were obtained by experiments.The results show that the new molten salts have much lower viscosities,thus suitable for reducing the flow resistance in transportation system of high-temperature solar thermal power generation. | CHEN YongChang WU YuTing REN Nan MA ChongFang | 2011 | Science China(Technological Sciences)2011，54，11： | 5 |
| 10 | Chemical formation and source apportionment of PM_(2.5) at an urban site at the southern foot of the Taihang mountains显示文摘The region along the Taihang Mountains in the North China Plain(NCP) is characterized by serious fine particle pollution. To clarify the formation mechanism and controlling factors, an observational study was conducted to investigate the physical and chemical properties of the fine particulate matter in Jiaozuo city, China. Mass concentrations of the water-soluble ions(WSIs) in PM_(2.5) and gaseous pollutant precursors were measured on an hourly basis from December 1, 2017, to February 27, 2018. The positive matrix factorization(PMF) method and the FLEXible PARTicle(FLEXPART) model were employed to identify the sources of PM_(2.5). The results showed that the average mass concentration of PM_(2.5) was 111 μg/m^(3) during the observation period. Among the major WSIs, sulfate, nitrate, and ammonium(SNA) constituted 62% of the total PM_(2.5) mass, and NO_(3)^(-) ranked the highest with an average contribution of 24.6%. NH_(4)^(+) was abundant in most cases in Jiaozuo. According to chemical balance analysis, SO_(2)-4, NO_(3)^(-), and Cl^(-) might be present in the form of(NH_4)_(2)SO_4, NH_4NO_3, NH_4Cl, and KCl. The liquid-phase oxidation of SO_(2) and NO_(2) was severe during the haze period. The relative humidity and pH were the key factors influencing SO_(4)^(2-) formation. We found that NO_(3)^(-) mainly stemmed from homogeneous gas-phase reactions in the daytime and originated from the hydrolysis of N_(2)O_5 in the nighttime, which was inconsistent with previous studies. The PMF model identified five sources of PM_(2.5) : secondary origin(37.8%), vehicular emissions(34.7%), biomass burning(11.5%), coal combustion(9.4%), and crustal dust(6.6%). | Xiaoyong Liu Mingshi Wang Xiaole Pan Xiyue Wang Xiaolong Yue Donghui Zhang Zhigang Ma Yu Tian Hang Liu Shandong Lei Yuting Zhang Qi Liao Baozhu Ge Dawei Wang Jie Li Yele Sun Pingqing Fu Zifa Wang Hong He | 2021 | Journal of Environmental Sciences2021，33，5： | 5 |
| 11 | Development and experimental study of a miniature vapor compression refrigeration equipment显示文摘A miniature vapor compression refrigeration equipment prototype was developed for a range of microclimate control applications, including man portable cooling and distributed space conditioning. The miniature refrigeration equipment has dimensions of 260 mm × 250 mm × 120 mm, and weighs approximately 2.85 kg. The optimal motor and its transmission ratio, the optimal dimension of capillary tube and the optimal quantity of refrigerant charge were obtained by matching and operating performance experimental study. Experimental results show that the miniature refrigeration equipment can provide 300 W cooling, and its COPc is above 2.0. | ZHONG XiaoHui GOU YuJun WU YuTing MA ChongFang | 2008 | Science China(Technological Sciences)2008，51，5： | 4 |
| 12 | Generation of obese rat model by transcription activator-like effector nucleases targeting the leptin receptor gene显示文摘The laboratory rat is a valuable mammalian model organism for basic research and drug discovery. Here we demonstrate an efficient methodology by applying transcription activator-like effector nucleases(TALENs) technology to generate Leptin receptor(Lepr) knockout rats on the Sprague Dawley(SD) genetic background. Through direct injection of in vitro transcribed m RNA of TALEN pairs into SD rat zygotes, somatic mutations were induced in two of three resulting pups. One of the founders carrying bi-allelic mutation exhibited early onset of obesity and infertility. The other founder carried a chimeric mutation which was efficiently transmitted to the progenies. Through phenotyping of the resulting three lines of rats bearing distinct mutations in the Lepr locus, we found that the strains with a frame-shifted or premature stop codon mutation led to obesity and metabolic disorders. However, no obvious defect was observed in a strain with an in-frame 57 bp deletion in the extracellular domain of Lepr. This suggests the deleted amino acids do not significantly affect Lepr structure and function. This is the first report of generating the Lepr mutant obese rat model in SD strain through a reverse genetic approach. This suggests that TALEN is an efficient and powerful gene editing technology for the generation of disease models. | Yuting Chen Wenqing Lu Na Gao Yi Long Yanjiao Shao Meizhen Liu Huaqing Chen Shixin Ye Xueyun Ma Mingyao Liu Dali Li | 2017 | Science China(Life Sciences)2017，60，2： | 4 |
| 13 | Performance study on three-stage power system of compressed air vehicle based on single-screw expander显示文摘A new compressed-air engine system based on three-stage single screw expander was proposed to improve the performance of power system.Three different structure styles were presented,and the studies on the power performance and the distribution of expansion ratios between stages were carried out by programming and mathematical modeling of each style.Research results indicated that the best matches of expansion ratios with equal heat temperature for the air tank of pressure 30 MPa were seven-five-three for'first-stage heating'style,eight-five-three for'two-stage heating'style and five-five-four for'three-stage heating'style,respectively.Results also showed that heating up inlet air or increasing the expander efficiency might improve the power performance.The output power of the'two-stage heating'style is far higher than that of'first-stage heating'style and is a little lower than that of'three-stage heating'style.The new system showed good structure and power performances. | HE Wei,WU YuTing ,MA ChongFang&MA GuoYuan Key Laboratory of Enhanced Heat Transfer and Energy Conservation,Ministry of Education,and Key Laboratory of Heat Transfer and Energy Conversion,Beijing Municipality,College of Environmental and Energy Engineering,Beijing University of Technology,Beijing 100124,China | 2010 | Science China(Technological Sciences)2010，53，8： | 3 |
| 14 | Efficient base editing in G/C-rich regions to model androgen insensitivity syndrome显示文摘Dear Editor, Most disease-associated genomic mutations are base substitutions and approximately half of pathogenic human single nucleotide polymorphisms (SNPs)are related to C-to-T substitutions in the ClinVar database.Base editors (BEs),which combine Casg-DIOA nickase and APOBEC (apolipoprotein B mRNA editing enzyme,catalytic polypeptide-like)or AID (activation-induced deaminase)cytidine deaminase family members, have been successfully applied to mediate C-to-T conversion in vitro and in vivo, providing a powerful tool to model or repair diseaserelated human SNPs. | Jianan Li Zhen Liu Shisheng Huang Xiao Wang Guanglei Li Yuting Xu Wenxia Yu Shanshan Chen Yu Zhang Hanhui Ma Zunfu Ke Jia Chen Qiang Sun Xingxu Huang | 2019 | Cell Research2019，29，2： | 3 |
| 15 | Domain Adaptation Network Based on Autoencoder显示文摘The domain adaptation uses labeled source domain data to train a classifier to be used in the target domain with no or small amount of labeled data. Usually there exists discrepancy in terms of marginal and conditional distributions for both source and target domains,which is of critical importance to minimize the distribution discrepancy between domains. As a classical model in deep learning, the autoencoder is capable of realizing distribution matching and enhancing classification accuracy by extracting more abstract and effective features from data. A Domain adaptation network based on autoencoder(DANA) is proposed. The DANA structure consists of a couple of encoding layers: a feature extraction layer and a classification layer. For the feature extraction layer,the marginal distributions of source and target domains are matched by using the nonparametric maximum mean discrepancy measurement. For the classification layer, the softmax regression model is applied to encode the label information of source domains meanwhile to match the conditional distribution. Experimental results on ImageNet,Corel and Leaves datasets have shown the enhanced classification accuracy by our proposed algorithm compared with the classical methods. | WANG Xuesong MA Yuting CHENG Yuhu | 2018 | Chinese Journal of Electronics2018，27，6： | 3 |
| 16 | Dissipative particle dynamics thermostat: a novel thermostat for molecular dynamics simulation of liquid crystals with Gay–Berne potential显示文摘The Gay–Berne(GB) model has been proved to be highly successful in the simulation of liquid crystal phases via both molecular dynamics(MD) and nonequilibrium molecular dynamics(NEMD). However, the conventional thermostats used in the simulations of GB systems, such as Nosé–Hoover and Langevin thermostats, have serious shortcomings especially in NEMD simulations. Recently, dissipative particle dynamics(DPD) has established itself as a useful thermostat for soft matter simulations, whereas the application of DPD thermostat in(NE)MD simulations is limited to the spherically isotropic potential models, such as the Lennard–Jones model. Considering the virtues of the DPD thermostat, that is, local, momentum conserved, and Galilean invariant, we extend the DPD thermostat to the non-spherical GB model. It is interesting to find that the translational DPD and rotational DPD thermostats can be used in the GB system independently and both can achieve the thermostatting effects. Also, we compared the performance of the DPD thermostat with other commonly used thermostats in NEMD simulations by investigating the streaming velocity profiles and the dynamics of phase separation in a typical but simple binary GB mixture under shear field. It is revealed that the known virtues of DPD thermostats, such as Galilean invariant, shear velocity profile-unbiased, and unscreened hydrodynamic interactions, are still intact when applying to GB systems. Finally, the appropriate parameters for the DPD thermostat in the GB system are identified for future investigations. | Yuting Ouyang Liang Hao Yanping Ma Hongxia Guo | 2015 | Science China Chemistry2015，58，4： | 3 |
| 17 | Erratum to:High-throughput fast full-color digital pathology based on Fourier ptychographic microscopy via color transfer [Sci. China-Phys. Mech. Astron. 64(11), 114211 (2021)]显示文摘In this paper[1],Figure 5(a)is mistakenly used with the figure of ground truth,which is taken and stitched by 10×/0.3NA objective and the operations have been detailed in the main text.The correction is as follows(Figure 1).This error does not affect the conclusion of this paper.The authors have also checked other figures such as Figure 6,and they are used correctly. | Yuting Gao Jiurun Chen Aiye Wang An Pan Caiwen Ma Baoli Yao | 2021 | Science China(Physics,Mechanics & Astronomy)2021，64，12： | 3 |
| 18 | Effects of Angelica sinensis extracts on lipid oxidation in fish feeds and growth performance of juvenile Jian carp(Cyprinus carpio var. Jian)显示文摘The study was to explore the effect of the extracts of Angelica sinensis(EAs) on lipid oxidation in fish feeds compared with ethoxyquin(EQ) and the effect of dietary EAs on growth performance of carp(Cyprinus carpio var. Jian). Firstly, fish feeds were respectively added with EQ, and ethyl ether extract ethyl acetate extract(EAE), acetone extract, ethanol extract(EE) and aqueous extract(AQE) of Angelica sinensis, except for the control. The results showed that EAs and EQ inhibited lipid oxidation in fish feed(P < 0.05). Of all of the examined EAs, EAE showed the strongest protective effects against lipid oxidation(P < 0.05). Moreover, EAE at high concentrations showed a stronger effect on lipid oxidation compared with EQ(P < 0.05). Then, 7 experimental diets respectively supplemented with 0.0, 1.0, 2.0, 3.0, 4.0, 5.0 and 6.0 g/kg of EAE were fed to the respective treatment groups for 30 d. Four replicates were performed for each treatment group; 20 carp(mean weight: 12.10 ± 0.13 g) were in each replicate. The result indicated that dietary EAE improved the growth performance in carp(P < 0.05). The appropriate con centration of EAE for carp growth was estimated to be 3.643 g/kg diet. Thus, EAE could be used as a natural antioxidant in feeds for Jian carp. | Huatao Li Dandan Yang Zhihao Li Mingquan He Fengyi Li Jun Jiang Siyi Tang Peiyuan Peng Wenhao Du Yuting Ma Ying Liu | 2019 | Animal Nutrition2019，，1： | 2 |
| 19 | Study of establishing disease-syndrome combined with animal model for immune thrombocytopenic purpura without additional conditions显示文摘Objective:To explore the feasibility of establishing the disease-syndrome combined animal model for immune thrombocytopenic purpura(ITP)without additional conditions.Methods:Three batches of data related to the ITP model mice obtained by replication at different time were analyzed,and whether the APS-injected model mice replicated through the passive immune modeling method could simulate the pathogenesis and clinical characteristics of human ITP was evaluated according to the differentiation criteria for diseasesyndrome combined model.Results:The APS-injected replicated ITP model mice possessed the following traits:(1)Compared with the normal group,the platelet count was significantly decreased,and coagulation time was significantly increased in the model group(P<.01).(2)Compared with the normal group,the medullary thrombocytogenous megakaryocytes were significantly decreased(P<.05,.01,.001).(3)The APS-injected sites and other parts of the model mice had spontaneous hemorrhage.(4)Behavioral changing signs were observed 1 week after the modeling(i.e.low activity,delayed activity,poor appetite,skin petechia/hemorrhage and spontaneous hemorrhage at the injected sites or other parts),and were getting more and more severe.Conclusion:According to the syndrome differentiation criteria for disease-syndrome combined model of ITP,the APS-injected animal model of ITP replicated through the passive immune modeling method without additional conditions possesses the characteristics of disease-syndrome combined model.It provides an ideal tool for the development of traditional Chinese medicine pharmacology experiment. | Haiyan Lang Ming Guo Yuting Chu Wei Ma Yayue Zhang Ling Zhang Xinyi Chen | 2016 | Journal of Traditional Chinese Medical Sciences2016，3，3： | 2 |
| 20 | Interactions between commensal bacteria and viral infection:insights for viral disease control in farmed animals显示文摘Viral diseases cause serious economic loss in farmed animals industry.However,the efficacy of remedies for viral infection in farmed animals is limited,and treatment strategies are generally lacking for aquatic animals.Interactions of commensal microbiota and viral infection have been studied in recent years,demonstrating a third player in the interaction between hosts and viruses.Here,we discuss recent developments in the research of interactions between commensal bacteria and viral infection,including both promotion and inhibition effect of commensal bacteria on viral pathogenesis,as well as the impact of viral infection on commensal microbiota.The antiviral effect of commensal bacteria is mostly achieved through priming or regulation of the host immune responses,involving differential microbial components and host signaling pathways,and gives rise to various antiviral probiotics.Moreover,we summarize studies related to the interaction between commensal bacteria and viral infection in farmed animals,including pigs,chickens,fish and invertebrate species.Further studies in this area will deepen our understanding of antiviral immunity of farmed animals in the context of commensal microbiota,and promote the development of novel strategies for treatment of viral diseases in farmed animals. | Chao Ran Yu Li Xufa Ma Yadong Xie Mingxu Xie Yuting Zhang Wei Zhou Yalin Yang Zhen Zhang Li Zhou Kaijian Wei Zhigang Zhou | 2021 | Science China(Life Sciences)2021，64，9： | 2 |
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