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| 1 | Non-invasive diagnosis of liver fibrosis and cirrhosis显示文摘The evaluation and follow up of liver fibrosis and cirrhosis have been traditionally performed by liver biopsy. However, during the last 20 years, it has become evident that this 'gold-standard' is imperfect; even according to its proponents, it is only 'the best' among available methods. Attempts at uncovering non-invasive diagnostic tools have yielded multiple scores, formulae, and imaging modalities. All are better tolerated, safer, more acceptable to the patient, and can be repeated essentially as often as required. Most are much less expensive than liver biopsy. Consequently, their use is growing, and in some countries the number of biopsies performed, at least for routine evaluation of hepatitis B and C, has declined sharply. However, the accuracy and diagnostic value of most, if not all, of these methods remains controversial. In this review for the practicing physician, we analyze established and novel biomarkers and physical techniques. We may be witnessing in recent years the beginning of the end of the first phase for the development of non-invasive markers. Early evidence suggests that they might be at least as good as liver biopsy. Novel experimental markers and imaging techniques could produce a dramatic change in diagnosis in the near future. | Yoav Lurie Muriel Webb Ruth Cytter-Kuint Shimon Shteingart Gerardo Z Lederkremer | 2015 | World Journal of Gastroenterology2015，21，41： | 36 |
| 2 | 下肢浅静脉治疗术后的加压疗法:美国静脉论坛血管、外科学会、美国静脉学会、血管医学学会和国际静脉联盟的临床实践指南显示文摘一、指南的由来下肢浅静脉治疗术后应用压力治疗的方式是几代血管外科医师多年临床经验积累所得,现主要应用于大隐静脉剥脱术、下肢静脉点状剥脱术及静脉硬化治疗等。目前单就静脉硬化治疗而言,术后压力治疗的推荐也是基于相关文献及实验验证[1],但对于其他术式,尤其是对于大隐静脉的热消融术,目前还没有形成规范统一的建议,这也使得当前的压力治疗具有很大的临床差异性。 | Lurie F Lal BK Antignani PL Blebea J Bush R Caprini J Davies A Forrestal M Jacobowitz G Kalodiki E Killewich L Lohr J Ma H Mosti G Partsch H Rooke T Wakefield T 李丹(译) 陈程浩(译) 牛传强(译) 张靖(译) 黄建忠(译) | 2020 | 中华介入放射学电子杂志2020，8，4： | 16 |
| 3 | Assessing adequacy of emergency provider documentation among interhospital transferred patients with acute aortic dissection显示文摘BACKGROUND: Acute aortic dissection(AoD) is a hypertensive emergency often requiring the transfer of patients to higher care hospitals; thus, clinical care documentation and compliance with the Emergency Medical Treatment and Active Labor Act(EMTALA) is crucial. The study assessed emergency providers(EP) documentation of clinical care and EMTALA compliance among interhospital transferred AoD patients.METHODS: This retrospective study examined adult patients transferred directly from a referring emergency department(ED) to a quaternary academic center between January 1, 2011 and September 30, 2015. The primary outcome was the percentage of records with adequate documentation of clinical care(ADoCC). The secondary outcome was the percentage of records with adequate documentation of EMTALA compliance(ADoEMTALA). RESULTS: There were 563 electronically identified patients with 287 included in the final analysis. One hundred and five(36.6%) patients had ADoCC while 166(57.8%) patients had ADoEMTALA. Patients with inadequate documentation of EMTALA(IDoEMTALA) were associated with a higher likelihood of not meeting the American Heart Association(AHA) ED Departure SBP guideline(OR 1.8, 95% CI 1.03–3.2, P=0.04). Male gender, handwritten type of documentation, and transport by air were associated with an increased risk of inadequate documentation of clinical care(IDoCC), while receiving continuous infusion was associated with higher risk of IDoEMTALA.CONCLUSION: Documentation of clinical care and EMTALA compliance by Emergency Providers is poor. Inadequate EMTALA documentation was associated with a higher likelihood of patients not meeting the AHA ED Departure SBP guideline. Therefore, Emergency Providers should thoroughly document clinical care and EMTALA compliance among this critically ill group before transfer. | Mark Rose Carina Newton Benchaa Boualam Nancy Bogne Adam Ketchum Umang Shah Jordan Mitchell Safura Tanveer Tucker Lurie Walesia Robinson Rebecca Duncan Stephen Thom Quincy Khoi Tran | 2019 | World Journal of Emergency Medicine2019，10，2： | 5 |
| 4 | FibroSURE^(TM) and FibroScan~ in relation to treatment response in chronic hepatitis C virus显示文摘AIM:To compare histological endpoint assessment using noninvasive alternatives to biopsy during treatment in a chronic hepatitis C virus(HCV)cohort.METHODS:Patients with chronic HCV were randomized to receive interferon-based therapy for 24(genotypes 2/3)or 48(genotype 1)wk.FibroSURE~TM(FS)was assessed at baseline and at week-12 post-treatment follow-up.Baseline biopsy for METAVIR was assessed by a single pathologist.FibroScan~ transient elastogra-phy(TE)was performed during treatment in a patient subset.RESULTS:Two thousand and sixty patients(n = 253 in Asia)were classif ied as METAVIR F0-1(n = 1682)or F2-4(n = 378).For F2-4,FS(n = 2055)had sensitiv-ity and specif icity of 0.87 and 0.61,respectively,with area under the receiver-operating curve of 0.82;corre-sponding values for TE(n = 214)and combined FS/TE(n = 209)were 0.77,0.88 and 0.88,and 0.93,0.68 and 0.88.Overall FS/TE agreement for F2-4 was 71%(κ = 0.41)and higher in Asians vs non-Asians(κ = 0.86 vs 0.35;P < 0.001).Combined FS/TE had 97% accuracy in Asians(n = 33).Baseline FS(0.38 vs 0.51,P < 0.001)and TE(8.0 kPa vs 11.9 kPa,P = 0.006)scores were lower in patients with sustained virological response than in nonresponders,and were maintained through follow-up.CONCLUSION:FS and TE may reliably differentiate mild from moderate-advanced disease,with a potential for high diagnostic accuracy in Asians with chronic HCV. | Keyur Patel Mireen Friedrich-Rust Yoav Lurie Mircea Grigorescu Carol Stanciu Chuan-Mo Lee Eugene R Schiff Dieter Hussinger Michael P Manns Guido Gerken Isabelle Colle Michael Torbenson Erik Pulkstenis G Mani Subramanian John G McHutchison Stefan Zeuzem | 2011 | World Journal of Gastroenterology2011，17，41： | 4 |
| 5 | Fundamental aspects of postharvest heat treatments显示文摘Heat treatments have been investigated for use in many aspects of postharvest storage.They have been developed for insect control,prevention of fungal development and prevention of postharvest storage disorders including chilling injury.The treatment times and temperature range vary widely,from days at 356C to 396C in hot air,to up to 636C for less than a minute in hot water.Much of the research has been performed to develop solutions to a particular problem,and less investigation has been conducted on the responses of the commodity to the treatment.However,since the turn of the century,a number of groups have been active in examining the molecular responses and changes that occur in commodities during and after the heat treatment.This review examines the changes at the level of transcriptome,proteome and metabolome that occur in response to the different heat treatments. | Susan Lurie Romina Pedreschi | 2014 | Horticulture Research2014，1，1： | 4 |
| 6 | Constant serum levels of secreted asialoglycoprotein receptor sH2a and decrease with cirrhosis显示文摘AIM: To investigate the existence and levels of sH2a, a soluble secreted form of the asialoglycoprotein receptor in human serum. METHODS: Production of recombinant sH2a and development of a monoclonal antibody and an enzyme-linked immunosorbent assay (ELISA). This assay was used to determine the presence and concentration of sH2a in human sera of individuals of both sexes and a wide range of ages. RESULTS: The recombinant protein was produced successfully and a specific ELISA assay was developed. The levels of sH2a in sera from 62 healthy individuals variedminimally (147 ± 19 ng/mL). In contrast, 5 hepatitis C patients with cirrhosis showed much decreased sH2a levels (50 ± 9 ng/mL). CONCLUSION: Constant sH2a levels suggest constitutive secretion from hepatocytes in healthy individuals. This constant level and the decrease with cirrhosis suggest a diagnostic potential. | Ron Benyair Maria Kondratyev Elena Veselkin Sandra Tol-chinsky Marina Shenkman Yoav Lurie Gerardo Z Lederkremer | 2011 | World Journal of Gastroenterology2011，17，48： | 3 |
| 7 | Long-Term Treatment With Entecavir Induces Reversal of Advanced Fibrosis or Cirrhosis in Patients With Chronic Hepatitis B显示文摘 | Eugene R. Schiff Samuel S. Lee You–Chen Chao Seung Kew Yoon Fernando Bessone Shun–Sheng Wu Wieslaw Kryczka Yoav Lurie Adrian Gadano George Kitis Suzanne Beebe Dong Xu Hong Tang Uchenna Iloeje | 2011 | Clinical Gastroenterology and Hepatology2011，，3： | 3 |
| 8 | 贮前热处理对苹果贮后品质的影响显示文摘为了寻求代替现行苹果贮前二苯胺处理(已限制使用)的方法,以前我们曾研究了热处理的效应,并指出供试的几个苹果品种的果实,在冷藏前置38℃下处理4天,增进了其贮后品质。但这样的热处理,能量消耗较大,商业上难以接受。本报告是关于贮前用高于38℃温度对苹果进行较短时间热处理,既降低了消耗又提高了其贮后品质的试验结果。 | Joshua D.klein Susan Lurie 萧韵琴 | 1993 | 北方果树1993，，2： | 3 |
| 9 | 儿童扩张型心肌病的发病率、病因及预后显示文摘背景:扩张型心肌病(dilated cardiomyopathy,DCM)是儿童心肌病最常见的类型,也是小儿心脏移植最常见的原因。但是,目前尚不清楚儿童DCM的流行病学特点和临床过程。
目的:详细描述儿童DCM的发病率、病因、预后及相关危险因素。
设计及地点:本项以人群为基础的前瞻性纵向队列研究入选1996年1月至2003年2月在89个儿科心脏中心诊断为DCM的儿童以及1990年1月至1995年12月在北美大型三级治疗中心诊断的患儿。
参试者:共入选1426例来自美国和加拿大的18岁以下DCM患儿。通过严格的超声心动图和/或病理学标准来诊断原发性DCM。因内分泌、免疫、药物中毒及其他原因患病者除外。
主要观测指标:每年每10万儿童的发病率、死亡率和心脏移植率。
结果:18岁以下儿童DCM每年的总发病率为0.57/10万,男孩的年发病率高于女孩(分别为0.66/10万和0.47/10万;P〈0.001),黑人的年发病率高于白人(分别为0.98/10万和0.46/10万;P〈0.001),婴儿(〈1岁)的年发病率高于儿童(分别为4.40/10万和0.34/10万;P〈0.001)。绝大部分属特发性,最常见的病因为心肌炎(46%)和神经肌肉性疾病(26%)。1年和5年死亡/移植率分别为31%和46%。死亡/移植的独立危险因素包括患儿诊断DCM时年龄较大、伴有充血性心力衰竭、左室收缩期Z评分较低以及DCM的病因(P均〈0.001)。
结论:儿童DCM有其多样性。患儿预后主要取决于病因、年龄和心力衰竭状况。人种、性别和年龄对发病率有一定影响。大部分患儿无明确病因,限制了特异性治疗。 | Jeffrey A. Towbin April M. Lowe Steven D. Colan Lynn A. Sleeper E. John Orav Sarah Clunie Jane Messere Gerald F. Cox Paul R. Lurie Daphne Hsu Charles Canter James D. Wilkinson Steven E. Lipshultz 康俊萍(译) 马长生(校) | 2007 | 美国医学会杂志(中文版)2007，26，4： | 3 |
| 10 | Developing Predictive Models of Health Literacy显示文摘 | Laurie T. Martin Teague Ruder José J. Escarce Bonnie Ghosh-Dastidar Daniel Sherman Marc Elliott Chloe E. Bird Allen Fremont Charles Gasper Arthur Culbert Nicole Lurie | 2009 | Journal of General Internal Medicine2009，，11： | 3 |
| 11 | Network Characteristics and the Value of Collaborative User-Generated Content显示文摘 | Sam Ransbotham Gerald C. Kane Nicholas H. Lurie | 2012 | Marketing Science2012，，3： | 2 |
| 12 | Effect of 1-methylcyclopropene on ripening of ‘Canino’ apricots and ‘Royal Zee’ plums显示文摘 | Li Dong Susan Lurie Hong-Wei Zhou | 2002 | Postharvest Biology and Technology2002，，2： | 2 |
| 13 | Ankle Fractures in the Elderly: What You Get Depends on Where You Live and Who You See显示文摘 | Kenneth J Koval Jon Lurie Weiping Zhou Michael B Sparks Robert V Cantu Scott M Sporer James Weinstein | 2005 | Journal of Orthopaedic Trauma2005，，9： | 2 |
| 14 | 贮藏前热处理延迟“澳洲青苹”苹果虎皮病的发生显示文摘'澳洲青苹'苹果在0℃的常规气体贮藏之前,于38℃下热处理4天,其虎皮病的发生得到抑制.热处理后的苹果贮藏三个月,其虎皮病的程度与二苯胺浸过的苹果相似,而未处理的对照苹果都有虎皮病。贮藏5或6个月后,贮藏前热处理的这种抑制作用降低了.贮前热处理抑制了贮藏期苹果表皮中α-法呢烯和共轭三烯的积累,而二苯胺只抑制了α-法呢烯的氧化.这种处理方法可代替预防虎皮病的化学处理不仅适用于短期贮藏的'澳洲青苹'苹果,而且可能还适用于其它易得虎皮病的品种. | Lurie 李丽萍 韩涛 关军锋 | 1991 | 国外农学(果树)1991，，3： | 2 |
| 15 | 宣教循证视频辅助决策对患者选择脊柱手术的影响显示文摘面对多个临床治疗方案,病人常常难以选择。决策辅助可增强患者对于疾病的认识,对减少决策冲突,提高患者在决策中的积极性有重要意义。 | Lurie JD Spratt KF Blood EA 陈旭琼 尹庆水 | 2011 | 中国骨科临床与基础研究杂志2011，3，3： | 2 |
| 16 | Postharvest heat treatment and fruit quality显示文摘 | Klein J D Lurie S | 1991 | Postharv News Info1991，2，1： | 1 |
| 17 | Subendometrial vasopressin to control intractable placental bleeding 显示文摘 | Lurie S Appelman Z Katz Z | 1997 | Lancet1997，349，9053： | 1 |
| 18 | Surgical management of deep venous reflux显示文摘 | Lurie F Kestner RL Eklof B | 2002 | Semin Vasc Surg2002，15，1： | 1 |
| 19 | Surgicalversus nonoperative treatment for lumbar spinal stenosis four-yearresults of the spine patient outcomes research trial显示文摘 | WE INSTEIN JN TOSTESON TD LURIE JD | 2010 | Spine2010，35，14： | 1 |
| 20 | The outcomes of elective laparoscopic and open cholecystectomies显示文摘 | Kane RL Lurie N Borbas C | 1995 | J Am Coil Surg1995，180，2： | 1 |
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